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  1. AU="Lee, Kristen"
  2. AU="Gentile, Giulia"
  3. AU="Shoben, Abigail B."
  4. AU="Rowe, Elizabeth"
  5. AU="Pandemic Response COVID-19 Research Collaboration Platform for HCQ/CQ Pooled Analyses"
  6. AU="Rahali, Anwar"
  7. AU="Zhang, Zhuang-Wei"
  8. AU="Townsend, Elizabeth C"
  9. AU="Lange, Mona V"
  10. AU="Bruner, Brenda G"
  11. AU="Michael Craigen"
  12. AU="Lambard, G."
  13. AU="Dempsey, Connor P"
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  1. Article ; Online: Educational attainment and emotional well-being in adolescence and adulthood.

    Lee, Kristen Schultz / Yang, Yulin

    SSM. Mental health

    2022  Volume 2

    Abstract: Education has been conceptualized as a causal factor leading to emotional well-being. However, it is also possible that some of the effect of education may be due to selection factors. Analyzing data from the National Longitudinal Study of Adolescent to ... ...

    Abstract Education has been conceptualized as a causal factor leading to emotional well-being. However, it is also possible that some of the effect of education may be due to selection factors. Analyzing data from the National Longitudinal Study of Adolescent to Adult Health (n = 10,908), we asked: to what extent does educational attainment increase emotional well-being once stable observed and unobserved individual characteristics are accounted for? Findings from fixed effects models showed that attaining a college degree was associated with greater emotional well-being. However, interactions with gender indicate that the positive association with emotional well-being is primarily for women, although a small negative association between completing college and depressive affect was found for men. These findings point to unmeasured confounding factors as motivating some of the association between educational attainment and emotional well-being among adolescents and adults.
    Language English
    Publishing date 2022-08-06
    Publishing country England
    Document type Journal Article
    ISSN 2666-5603
    ISSN (online) 2666-5603
    DOI 10.1016/j.ssmmh.2022.100138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Measuring context-response associations that drive habits.

    Labrecque, Jennifer S / Lee, Kristen M / Wood, Wendy

    Journal of the experimental analysis of behavior

    2023  Volume 121, Issue 1, Page(s) 62–73

    Abstract: People achieve important life outcomes of health, financial security, and productivity by repeating operant behavior. To identify whether such operants reflect goal pursuit or habit, the present research introduces a new paradigm that yields objective ... ...

    Abstract People achieve important life outcomes of health, financial security, and productivity by repeating operant behavior. To identify whether such operants reflect goal pursuit or habit, the present research introduces a new paradigm that yields objective measures of learning and controls for the motivations of goal pursuit. In two experiments, participants practiced a sequential task of making sushi and then completed a test of the strength of cue-response (habit) associations in memory. Finally, they repeated the sushi task without instructions while under cognitive load (designed to impede deliberation about goals). As predicted, greater task practice yielded stronger cue-response associations, which in turn promoted task success. Practice did not improve performance by enhancing goal intentions or other task motivations. We conclude that repetition facilitates performance by creating mental associations that automatically activate practiced, habitual responses upon perception of recurring context cues.
    MeSH term(s) Humans ; Motivation ; Cues ; Habits
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219405-3
    ISSN 1938-3711 ; 0022-5002
    ISSN (online) 1938-3711
    ISSN 0022-5002
    DOI 10.1002/jeab.893
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  3. Article ; Online: Different roles of interpersonal trust and institutional trust in motivating older adults to receive COVID-19 vaccines in Singapore.

    Yuan, Yaqi / Yeo, Shun Yuan / Lee, Kristen Schultz

    Social science & medicine (1982)

    2023  Volume 340, Page(s) 116475

    Abstract: Since the approvals of several vaccines against COVID-19 by the World Health Organization, a large body of research has studied the determinants of individuals' intention to be vaccinated against COVID-19 in a variety of societies. Vaccine intention is a ...

    Abstract Since the approvals of several vaccines against COVID-19 by the World Health Organization, a large body of research has studied the determinants of individuals' intention to be vaccinated against COVID-19 in a variety of societies. Vaccine intention is a complex construct rooted in the social context that informs the decision-making process. The underlying reasons for older adults' intention to receive the vaccination is even more important to health authorities in societies with large proportions of older adults. In this paper, we interview 27 women over age 55 in Singapore about their COVID-19 vaccine decision-making. Using a social-ecological framework of trust, we identify factors at both individual and institutional levels that build or undermine trust and underlie older women's decisions to receive COVID-19 vaccinations in an authoritarian regime. Findings show that both interpersonal trust and institutional trust contribute to vaccine uptake, however, trust can also contribute to delays in vaccination. Moreover, a sizable minority of respondents report that they were vaccinated not because of institutional trust, but because they felt compelled to do so. The results shed light on directions for future vaccination campaigns.
    MeSH term(s) Female ; Humans ; Aged ; Middle Aged ; COVID-19 Vaccines/therapeutic use ; COVID-19/epidemiology ; COVID-19/prevention & control ; Singapore ; Trust ; Authoritarianism ; Intention ; Vaccination ; Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2023-12-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2023.116475
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    Zs.A 625: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Adult Children's Educational Attainment and Parent Health in Mid- and Later-Life.

    Dennison, Christopher R / Lee, Kristen Schultz

    The journals of gerontology. Series B, Psychological sciences and social sciences

    2021  Volume 76, Issue 9, Page(s) 1857–1869

    Abstract: Objectives: Intergenerational models of adult health contend that children's educational attainments influence the health and well-being of their parents. However, it is unclear how much of this association is confounded by background characteristics ... ...

    Abstract Objectives: Intergenerational models of adult health contend that children's educational attainments influence the health and well-being of their parents. However, it is unclear how much of this association is confounded by background characteristics that predict both children's educational attainments and parents' subsequent health, particularly in the United States.
    Methods: Data from the National Longitudinal Study of Adolescent to Adult Health Parent Study are used to examine how having no children who completed college influences parents' self-rated health and depressive symptoms. We rely on propensity score methods to more squarely assess this relationship net of potential confounding bias and to test for heterogeneity in the consequences associated with having no children who completed college.
    Results: Having no children who completed college is negatively associated with parents' self-rated health and positively associated with depressive symptoms. After statistically balancing differences in background characteristics between groups, these associations remain, though the magnitude of the coefficients is attenuated. Supplemental matching analyses suggest that while the association between children's education and self-rated health might be spurious, the association with depressive symptoms is more robust. Additionally, among parents with the highest propensity for having no children who complete college, the consequences on depressive symptoms are greatest.
    Discussion: This study pays particular attention to selection-related concerns surrounding the association between offspring educational attainment and parent well-being in the United States. These findings are important given the call for investments in children's educational opportunities as promoting both the well-being of adult children and their parents.
    MeSH term(s) Adult ; Adult Children ; Aged ; Aged, 80 and over ; Depression/epidemiology ; Educational Status ; Female ; Health Inequities ; Health Status ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Parents ; United States/epidemiology
    Language English
    Publishing date 2021-06-16
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1223664-0
    ISSN 1758-5368 ; 1079-5014
    ISSN (online) 1758-5368
    ISSN 1079-5014
    DOI 10.1093/geronb/gbab109
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  5. Article ; Online: A locomotor neural circuit persists and functions similarly in larvae and adult

    Lee, Kristen / Doe, Chris Q

    eLife

    2021  Volume 10

    Abstract: Individual neurons can undergo drastic structural changes, known as neuronal remodeling or structural plasticity. One example of this is in response to hormones, such as during puberty in mammals or metamorphosis in insects. However, in each of these ... ...

    Abstract Individual neurons can undergo drastic structural changes, known as neuronal remodeling or structural plasticity. One example of this is in response to hormones, such as during puberty in mammals or metamorphosis in insects. However, in each of these examples, it remains unclear whether the remodeled neuron resumes prior patterns of connectivity, and if so, whether the persistent circuits drive similar behaviors. Here, we utilize a well-characterized neural circuit in the
    MeSH term(s) Animals ; Drosophila/physiology ; Drosophila melanogaster/physiology ; Interneurons ; Larva/physiology ; Locomotion/physiology ; Metamorphosis, Biological/physiology ; Motor Neurons/physiology ; Neuronal Plasticity ; Optogenetics ; Synapses
    Language English
    Publishing date 2021-07-14
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.69767
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  6. Article ; Online: Developmental origin of the Pair1 descending interneuron.

    Linskens, Amanda / Doe, Chris / Lee, Kristen

    microPublication biology

    2022  Volume 2022

    Abstract: Pair1 is part of ... ...

    Abstract Pair1 is part of a
    Language English
    Publishing date 2022-12-16
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000707
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  7. Article ; Online: Hunchback activates Bicoid in Pair1 neurons to regulate synapse number and locomotor circuit function.

    Lee, Kristen M / Linskens, Amanda M / Doe, Chris Q

    Current biology : CB

    2022  Volume 32, Issue 11, Page(s) 2430–2441.e3

    Abstract: Neural circuit function underlies cognition, sensation, and behavior. Proper circuit assembly depends on the identity of the neurons in the circuit (gene expression, morphology, synapse targeting, and biophysical properties). Neuronal identity is ... ...

    Abstract Neural circuit function underlies cognition, sensation, and behavior. Proper circuit assembly depends on the identity of the neurons in the circuit (gene expression, morphology, synapse targeting, and biophysical properties). Neuronal identity is established by spatial and temporal patterning mechanisms, but little is known about how these mechanisms drive circuit formation in postmitotic neurons. Temporal patterning involves the sequential expression of transcription factors (TFs) in neural progenitors to diversify neuronal identity, in part through the initial expression of homeodomain TF combinations. Here, we address the role of the Drosophila temporal TF Hunchback and the homeodomain TF Bicoid in the assembly of the Pair1 (SEZ_DN1) descending neuron locomotor circuit, which promotes larval pausing and head casting. We find that both Hunchback and Bicoid are expressed in larval Pair1 neurons, Hunchback activates Bicoid in Pair1 (opposite of their embryonic relationship), and the loss of Hunchback function or Bicoid function from Pair1 leads to ectopic presynapse numbers in Pair1 axons and an increase in Pair1-induced pausing behavior. These phenotypes are highly specific, as the loss of Bicoid or Hunchback has no effect on Pair1 neurotransmitter identity, dendrite morphology, or axonal morphology. Importantly, the loss of Hunchback or Bicoid in Pair1 leads to the addition of new circuit partners that may underlie the exaggerated locomotor pausing behavior. These data are the first to show a role for Bicoid outside of embryonic patterning and the first to demonstrate a cell-autonomous role for Hunchback and Bicoid in interneuron synapse targeting and locomotor behavior.
    MeSH term(s) Animals ; Drosophila/physiology ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Gene Expression Regulation, Developmental ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Larva/metabolism ; Neurons/metabolism ; Synapses/metabolism
    Chemical Substances Drosophila Proteins ; Homeodomain Proteins
    Language English
    Publishing date 2022-05-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2022.04.025
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    Zs.A 3208: Show issues Location:
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  8. Article ; Online: Conflicting views on elder care responsibility in Japan.

    Lee, Kristen Schultz

    Social science research

    2016  Volume 57, Page(s) 133–147

    Abstract: I examine the attitudinal ambivalence created by conflicting social expectations regarding parent-child devotion, filial obligation and family membership, and gender norms in a national population of Japanese adults. I ask: in a context of rapidly ... ...

    Abstract I examine the attitudinal ambivalence created by conflicting social expectations regarding parent-child devotion, filial obligation and family membership, and gender norms in a national population of Japanese adults. I ask: in a context of rapidly changing family and elder care norms, how do different beliefs and attitudes overlap and conflict and how are they related to elder care preferences? I analyze data from the 2006 Japanese General Social Survey and use Latent Class Analysis to identify latent groups in the population defined by their beliefs and examine the relationship between class membership and elder care preferences. I found variation in the population with respect to the measured beliefs as well as a relationship between patterns of beliefs and choice of elder caregiver. I found conflicting expectations regarding elder care responsibility in one latent class and this class also expressed elder care preferences that conflict with at least some of their strongly held beliefs.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Attitude ; Caregivers ; Culture ; Female ; Gender Identity ; Humans ; Intergenerational Relations ; Japan ; Male ; Middle Aged ; Parent-Child Relations ; Social Behavior ; Social Norms ; Social Responsibility ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2016-05
    Publishing country United States
    Document type Journal Article
    ISSN 1096-0317
    ISSN (online) 1096-0317
    DOI 10.1016/j.ssresearch.2016.01.003
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  9. Article ; Online: Utilizing Telemedicine and Modified Fibrosis Staging Protocols to Maintain Treatment Initiation and Adherence Among Hepatitis C Patients During the COVID-19 Pandemic.

    O'Brien, Matthew / Daws, Rachel / Amin, Pooja / Lee, Kristen

    Journal of primary care & community health

    2022  Volume 13, Page(s) 21501319221108000

    Abstract: The COVID-19 pandemic exacerbated the decline in Hepatitis C Virus (HCV) screening and treatment globally in part due to lockdowns and restrictions at healthcare centers. The goal of this retrospective cohort study was to assess the effectiveness of an ... ...

    Abstract The COVID-19 pandemic exacerbated the decline in Hepatitis C Virus (HCV) screening and treatment globally in part due to lockdowns and restrictions at healthcare centers. The goal of this retrospective cohort study was to assess the effectiveness of an updated workflow implemented at Boston Medical Center (BMC) HCV clinics. Revised workflow incorporated appointments via telemedicine, transitioning to blood test-based fibrosis scoring, and delivering medication by mail to mitigate the lack of in-person services. We compared 2 cohorts of patients who attended at least the initial intake appointment at BMCHCV clinics: 170 before the pandemic and 133 after the pandemic. Outcome variables included treatment starts, fibrosis lab tests completed, appointment attendance, and SVR achievement. Proportions for outcome variables were compared between groups by use of χ
    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19 ; Communicable Disease Control ; Fibrosis ; Hepacivirus ; Hepatitis C/diagnosis ; Hepatitis C/drug therapy ; Humans ; Pandemics ; Retrospective Studies ; Telemedicine
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2022-07-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2550221-9
    ISSN 2150-1327 ; 2150-1319
    ISSN (online) 2150-1327
    ISSN 2150-1319
    DOI 10.1177/21501319221108000
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  10. Article ; Online: Infrarenal Aortic Aneurysm in a Patient with Remote History of Liver Transplant with Aorto-Hepatic Conduit.

    McGevna, Moira A / Pierce, Anne / Lu, James Y / Borole, Aryan / Lee, Kristen / Beckerman, William E

    Journal of vascular surgery

    2024  

    Language English
    Publishing date 2024-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2024.04.065
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