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  1. Article ; Online: Investigation and assessment of natural radioactivity in commercial animal feeds in Texas.

    Lee, Kyung-Min / Herrman, Timothy J

    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

    2024  Volume 41, Issue 1, Page(s) 33–44

    Abstract: Commercial animal feed in Texas was characterized by determining natural gamma emitters ... ...

    Abstract Commercial animal feed in Texas was characterized by determining natural gamma emitters including
    MeSH term(s) Animals ; Cattle ; Radioactivity ; Texas ; Lead ; Cesium Radioisotopes/analysis ; Animal Feed/analysis ; Minerals ; Vitamins ; Soil Pollutants, Radioactive/analysis
    Chemical Substances Lead (2P299V784P) ; Cesium-137 (4T2E65IAR7) ; Cesium Radioisotopes ; Minerals ; Vitamins ; Soil Pollutants, Radioactive
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2462951-0
    ISSN 1944-0057 ; 1944-0049
    ISSN (online) 1944-0057
    ISSN 1944-0049
    DOI 10.1080/19440049.2023.2289132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ddRAD Sequencing and DNA Barcoding.

    Ivanov, Vladislav / Lee, Kyung Min / Mutanen, Marko

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2744, Page(s) 213–221

    Abstract: Double-digest restriction site-associated DNA sequencing is a library preparation protocol that enables capturing variable sites across the genome including single-nucleotide polymorphisms (SNPs). These SNPs can be utilized to gain evolutionary insights ... ...

    Abstract Double-digest restriction site-associated DNA sequencing is a library preparation protocol that enables capturing variable sites across the genome including single-nucleotide polymorphisms (SNPs). These SNPs can be utilized to gain evolutionary insights into patterns observed in DNA barcodes, to infer population structure and phylogenies, to detect gene flow and introgression, and to perform species delimitation analyses. The protocol includes chemically shearing genomic DNA with restriction enzymes, unique tagging, size selection, and amplification of the resulting DNA fragments. Here we provide a detailed description of each step of the protocol, as well as information on essential equipment and common issues encountered during laboratory work.
    MeSH term(s) DNA Barcoding, Taxonomic/methods ; Polymorphism, Single Nucleotide ; Sequence Analysis, DNA/methods ; High-Throughput Nucleotide Sequencing/methods ; DNA/genetics ; Gene Library ; Humans
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3581-0_13
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: ECM1 is associated with endocrine resistance in ER

    Lee, Tae Won / Lee, Kyung-Min

    Animal cells and systems

    2022  Volume 26, Issue 3, Page(s) 99–107

    Abstract: Extracellular matrix protein 1 (ECM1) is associated with a poor prognosis of breast cancers. However, the role of ECM1 with endocrine resistance in estrogen receptor-positive ( ... ...

    Abstract Extracellular matrix protein 1 (ECM1) is associated with a poor prognosis of breast cancers. However, the role of ECM1 with endocrine resistance in estrogen receptor-positive (ER
    Language English
    Publishing date 2022-06-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2562988-8
    ISSN 2151-2485 ; 1976-8354
    ISSN (online) 2151-2485
    ISSN 1976-8354
    DOI 10.1080/19768354.2022.2083235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Determination of Mouth Width for Facial Reconstruction Based on Statistical Regression Model.

    Zhang, MeiLing / Xu, Huiming / Biao, Yan / Lee, KyungMin Clara

    The Journal of craniofacial surgery

    2024  

    Abstract: Introduction: It is important to generate predictable statistical models by increasing the number of variables on the human skeletal and soft tissue structures on the face to increase the accuracy of human facial reconstructions. The purpose of this ... ...

    Abstract Introduction: It is important to generate predictable statistical models by increasing the number of variables on the human skeletal and soft tissue structures on the face to increase the accuracy of human facial reconstructions. The purpose of this study was to determine mouth width 3-dimensionally based on statistical regression model.
    Material and methods: Cone-beam computed tomography scan data from 130 individuals were used to measure the horizontal and vertical dimensions of orbital and nasal structures and intercanine width. The correlation between these hard tissue variables and the mouth width was evaluated using the statistical regression model.
    Results: Orbital width, nasal width, and intercanine width were found to be strong predictors of the mouth width determination and were used to generate the regression formulae to find the most approximate position of the mouth.
    Conclusion: These specific variables may contribute to improving the accuracy of mouth width determination for oral and maxillofacial reconstructions.
    Language English
    Publishing date 2024-05-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000010191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3761: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 175: Show issues

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  5. Article ; Online: Differences between DNA vaccine and single-cycle viral vaccine in the ability of cross-protection against viral hemorrhagic septicemia virus (VHSV) and infectious hematopoietic necrosis virus (IHNV).

    Kim, So Yeon / Lee, Kyung Min / Kim, Ki Hong

    Vaccine

    2023  Volume 41, Issue 38, Page(s) 5580–5586

    Abstract: Vaccination procedures can be stressful for fish and can bring severe side effects. Therefore, vaccines that can minimize the number of administrations and maximize cross-protection against multiple serotypes, genotypes, or even different species would ... ...

    Abstract Vaccination procedures can be stressful for fish and can bring severe side effects. Therefore, vaccines that can minimize the number of administrations and maximize cross-protection against multiple serotypes, genotypes, or even different species would be highly advantageous. In the present study, we investigated the cross-protective ability of two types of vaccines - viral hemorrhagic septicemia virus (VHSV) G protein-expressing DNA vaccine and G gene-deleted single-cycle VHSV genotype IVa (rVHSV-ΔG) vaccine - against both VHSV genotype Ia and infectious hematopoietic necrosis virus (IHNV) in rainbow trout (Oncorhynchus mykiss). The results showed that rainbow trout immunized with VHSV genotype Ia G gene- or IVa G gene-expressing DNA vaccine were significantly protected against VHSV genotype Ia, but were not protected against IHNV. In contrast to the DNA vaccine, the single-cycle VHSV IVa vaccine induced significant protection against not only VHSV Ia but also IHNV. Considering no significant increase in ELISA titer and serum neutralization activity against IHNV in fish immunized with single-cycle VHSV IVa, the protection might be independent of humoral adaptive immunity. The scarcity of cytotoxic T cell epitopes between VHSV and IHNV suggested that the possibility of involvement of cytotoxic T cell-mediated cellular adaptive immunity would be low. The role of trained immunity (innate immune memory) in cross-protection should be further investigated.
    MeSH term(s) Animals ; Infectious hematopoietic necrosis virus/genetics ; Vaccines, DNA ; Viral Vaccines ; Novirhabdovirus/genetics ; Immunization ; Oncorhynchus mykiss ; Fish Diseases ; Hemorrhagic Septicemia, Viral/prevention & control ; Rhabdoviridae Infections/prevention & control ; Rhabdoviridae Infections/veterinary
    Chemical Substances Vaccines, DNA ; Viral Vaccines
    Language English
    Publishing date 2023-07-29
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.07.058
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1930: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 458: Show issues

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  6. Article ; Online: Comparison of two intraoral scanners based on three-dimensional surface analysis.

    Lee, Kyung-Min

    Progress in orthodontics

    2018  Volume 19, Issue 1, Page(s) 6

    Abstract: Background: This in vivo study evaluated the difference of two well-known intraoral scanners used in dentistry, namely iTero (Align Technology) and TRIOS (3Shape).: Methods: Thirty-two participants underwent intraoral scans with TRIOS and iTero ... ...

    Abstract Background: This in vivo study evaluated the difference of two well-known intraoral scanners used in dentistry, namely iTero (Align Technology) and TRIOS (3Shape).
    Methods: Thirty-two participants underwent intraoral scans with TRIOS and iTero scanners, as well as conventional alginate impressions. The scans obtained with the two intraoral scanners were compared with each other and were also compared with the corresponding model scans by means of three-dimensional surface analysis. The average differences between the two intraoral scans on the surfaces were evaluated by color-mapping. The average differences in the three-dimensional direction between each intraoral scans and its corresponding model scan were calculated at all points on the surfaces.
    Results: The average differences between the two intraoral scanners were 0.057 mm at the maxilla and 0.069 mm at the mandible. Color histograms showed that local deviations between the two scanners occurred in the posterior area. As for difference in the three-dimensional direction, there was no statistically significant difference between two scanners.
    Conclusions: Although there were some deviations in visible inspection, there was no statistical significance between the two intraoral scanners.
    MeSH term(s) Computer-Aided Design ; Dental Impression Materials ; Dental Impression Technique ; Dental Models ; Dimensional Measurement Accuracy ; Humans ; Image Processing, Computer-Assisted/instrumentation ; Imaging, Three-Dimensional/instrumentation
    Chemical Substances Dental Impression Materials
    Language English
    Publishing date 2018-02-12
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 2040711-7
    ISSN 2196-1042 ; 1600-9975 ; 1723-7785 ; 1399-7513
    ISSN (online) 2196-1042 ; 1600-9975
    ISSN 1723-7785 ; 1399-7513
    DOI 10.1186/s40510-018-0205-5
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5560: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The incidence of the healthcare costs of chronic conditions.

    Lee, Kyung Min / Jeung, Chanup

    International journal of health economics and management

    2021  Volume 21, Issue 4, Page(s) 473–493

    Abstract: Who pays for the costs of chronic conditions? In this paper, we examine whether 50-64-year old workers covered by employer-sponsored insurance bear healthcare costs of chronic conditions in the form of lower wages. Using a difference-in-differences ... ...

    Abstract Who pays for the costs of chronic conditions? In this paper, we examine whether 50-64-year old workers covered by employer-sponsored insurance bear healthcare costs of chronic conditions in the form of lower wages. Using a difference-in-differences approach with data from the Health and Retirement Study, we find that workers with chronic diseases receive significantly lower wages than healthy workers when they are covered by employer-sponsored insurance. Our findings suggest that higher healthcare costs of chronic conditions can explain the substantial part of the wage gap between workers with and without chronic diseases.
    MeSH term(s) Chronic Disease ; Employer Health Costs ; Humans ; Incidence ; Insurance ; Middle Aged ; Salaries and Fringe Benefits
    Language English
    Publishing date 2021-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2817492-6
    ISSN 2199-9031 ; 2199-9023
    ISSN (online) 2199-9031
    ISSN 2199-9023
    DOI 10.1007/s10754-021-09305-6
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  8. Article: Enhanced Skin Permeation of 5-Fluorouracil through Drug-in-Adhesive Topical Patches.

    Kim, Sangseo / Youssef, Souha H / Lee, Kyung Min Kirsten / Song, Yunmei / Vaidya, Sachin / Garg, Sanjay

    Pharmaceutics

    2024  Volume 16, Issue 3

    Abstract: 5-fluorouracil (5-FU), commercially available as a topical product, is approved for non-melanoma skin cancer (NMSC) treatment with several clinical limitations. This work aimed to develop 5-FU-loaded topical patches as a potential alternative to overcome ...

    Abstract 5-fluorouracil (5-FU), commercially available as a topical product, is approved for non-melanoma skin cancer (NMSC) treatment with several clinical limitations. This work aimed to develop 5-FU-loaded topical patches as a potential alternative to overcome such drawbacks. The patches offer accurate dosing, controlled drug release and improved patient compliance. Our study highlights the development of Eudragit
    Language English
    Publishing date 2024-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics16030379
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  9. Article: ECM1 is associated with endocrine resistance in ER⁺ breast cancers

    Lee, Tae Won / Lee, Kyung-min

    Animal cells and systems. 2022 May 04, v. 26, no. 3

    2022  

    Abstract: Extracellular matrix protein 1 (ECM1) is associated with a poor prognosis of breast cancers. However, the role of ECM1 with endocrine resistance in estrogen receptor-positive (ER⁺) breast cancers has not been elucidated yet. We show that ECM1 promotes ... ...

    Abstract Extracellular matrix protein 1 (ECM1) is associated with a poor prognosis of breast cancers. However, the role of ECM1 with endocrine resistance in estrogen receptor-positive (ER⁺) breast cancers has not been elucidated yet. We show that ECM1 promotes endocrine resistance in ER⁺ breast cancers. ECM1 is overexpressed in luminal breast cancer patients compared to the basal type of breast cancer. Significantly, higher expression of ECM1 is associated with poor response to endocrine therapies in luminal B breast cancer patients. We found that ECM1 is upregulated in CAMA1 and MDA-MB-361 cells grown in long-term estrogen-deprived (LTED) conditions. Moreover, the ablation of ECM1 significantly inhibited the proliferation of CAMA1 LTED and MDA-MB-361 LTED cells. Finally, an interrogation of a dataset containing transcriptome and proteome of breast cancer cell lines revealed that the level of ECM1 mRNA is positively correlated with that of phosphorylated Src. Based on these findings, we strongly suggest that ECM1 significantly contributes to the acquisition of endocrine resistance in ER⁺ breast cancers by the activation of Src.
    Keywords animals ; breast neoplasms ; breasts ; data collection ; estrogens ; extracellular matrix ; neoplasm cells ; prognosis ; proteome ; transcriptome
    Language English
    Dates of publication 2022-0504
    Size p. 99-107.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2562988-8
    ISSN 2151-2485 ; 1976-8354
    ISSN (online) 2151-2485
    ISSN 1976-8354
    DOI 10.1080/19768354.2022.2083235
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Special Issue: Resistance to Targeted Therapies in Human Cancer.

    Lee, Tae-Won / Choi, Hee-Joo / Lee, Kyung-Min / Lee, Jeong-Yeon

    Biomedicines

    2023  Volume 11, Issue 2

    Abstract: Cancer is the second leading cause of death worldwide, accounting for approximately 10 million deaths in 2020 [ ... ]. ...

    Abstract Cancer is the second leading cause of death worldwide, accounting for approximately 10 million deaths in 2020 [...].
    Language English
    Publishing date 2023-01-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11020414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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