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  1. Article ; Online: Shared grey matter correlates of reading and attention.

    Lee, Marissa M / Drury, Brianne C / McGrath, Lauren M / Stoodley, Catherine J

    Brain and language

    2023  Volume 237, Page(s) 105230

    Abstract: Disorders of reading (developmental dyslexia) and attention (ADHD) have a high rate of comorbidity (25-40%), yet little is known about the neural underpinnings of this phenomenon. The current study investigated the shared and unique neural correlates of ... ...

    Abstract Disorders of reading (developmental dyslexia) and attention (ADHD) have a high rate of comorbidity (25-40%), yet little is known about the neural underpinnings of this phenomenon. The current study investigated the shared and unique neural correlates of reading and attention in 330 typically developing children ages 8-18 from the Philadelphia Neurodevelopmental Cohort. Multiple regression analyses were used to identify regions of the brain where grey matter (GM) volume was associated with reading or attention scores (p < 0.001, cluster FDR p < 0.05). Better attention scores correlated with increased GM in the precuneus and higher reading scores were associated with greater thalamic GM. An exploratory conjunction analysis (p < 0.05, k > 239) found that GM in the caudate and precuneus correlated with both reading and attention scores. These results are consistent with a recent meta-analysis which identified GM reductions in the caudate in both dyslexia and ADHD and reveal potential shared neural correlates of reading and attention.
    MeSH term(s) Child ; Humans ; Adolescent ; Gray Matter/diagnostic imaging ; Reading ; Magnetic Resonance Imaging/methods ; Attention Deficit Disorder with Hyperactivity/diagnostic imaging ; Dyslexia/diagnostic imaging
    Language English
    Publishing date 2023-02-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 7448-2
    ISSN 1090-2155 ; 0093-934X
    ISSN (online) 1090-2155
    ISSN 0093-934X
    DOI 10.1016/j.bandl.2023.105230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical Reasoning: A neonate with micrognathia and hypotonia.

    Vawter-Lee, Marissa M / Seals, Shannon S / Thomas, Cameron W / Venkatesan, Charu

    Neurology

    2016  Volume 86, Issue 8, Page(s) e80–4

    MeSH term(s) Adult ; Diagnosis, Differential ; Female ; Humans ; Infant, Newborn ; Micrognathism/complications ; Micrognathism/diagnosis ; Muscle Hypotonia/complications ; Muscle Hypotonia/diagnosis
    Language English
    Publishing date 2016-02-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000002397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Outcome of Isolated Absent Septum Pellucidum Diagnosed by Fetal Magnetic Resonance Imaging (MRI) Scan.

    Vawter-Lee, Marissa M / Wasserman, Halley / Thomas, Cameron W / Nichols, Beatrice / Nagaraj, Usha D / Schapiro, Mark / Venkatesan, Charu

    Journal of child neurology

    2018  Volume 33, Issue 11, Page(s) 693–699

    Abstract: Improved fetal imaging has resulted in increased diagnosis of isolated absent septum pellucidum without other intracranial abnormalities. There is little literature regarding outcomes for these fetuses. This study hypothesized the majority of infants ... ...

    Abstract Improved fetal imaging has resulted in increased diagnosis of isolated absent septum pellucidum without other intracranial abnormalities. There is little literature regarding outcomes for these fetuses. This study hypothesized the majority of infants diagnosed by fetal magnetic resonance imaging (MRI) with isolated absent septum pellucidum would retain this diagnosis postnatally. Specifically, in the absence of postnatal endocrine or ophthalmologic abnormalities, postnatal imaging would find no additional related findings, and fetuses would be at low risk for developmental delay. Two of 8 subjects met postnatal criteria for septo-optic dysplasia; remaining subjects had normal postnatal endocrine and ophthalmologic evaluations and no significant related findings on postnatal MRI. One subject without septo-optic dysplasia had delays on developmental screening; all others had normal screening (range of follow-up 8-72 months). Our study questions the necessity of postnatal imaging for prenatally diagnosed isolated absent septum pellucidum. Majority of fetuses with isolated absent septum pellucidum retained this diagnosis postnatally.
    MeSH term(s) Child ; Child, Preschool ; Cohort Studies ; Female ; Fetus ; Gestational Age ; Humans ; Image Processing, Computer-Assisted ; Infant ; Magnetic Resonance Imaging ; Male ; Maternal Age ; Pregnancy ; Septo-Optic Dysplasia/diagnostic imaging
    Language English
    Publishing date 2018-06-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639288-x
    ISSN 1708-8283 ; 0883-0738
    ISSN (online) 1708-8283
    ISSN 0883-0738
    DOI 10.1177/0883073818783460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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