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  1. Article: A case of type A insulin resistance syndrome in a 14-year-old adolescent girl without common clinical features.

    Lee, Na Won / Jeong, Ji Eun / Kim, Young Hwan / Ki, Chang Seok / Kim, Jin Kyung

    Annals of pediatric endocrinology & metabolism

    2023  Volume 28, Issue Suppl 1, Page(s) S17–S19

    Language English
    Publishing date 2023-02-01
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2800460-7
    ISSN 2287-1292 ; 2287-1012
    ISSN (online) 2287-1292
    ISSN 2287-1012
    DOI 10.6065/apem.2244106.053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Optimization of the enzymatic production of 20(S)-ginsenoside Rg(3) from white ginseng extract using response surface methodology.

    Chang, Kyung-Hoon / Jee, Hee Sook / Lee, Na-Kyoung / Park, Se-Ho / Lee, Na-Won / Paik, Hyun-Dong

    New biotechnology

    2009  Volume 26, Issue 3-4, Page(s) 181–186

    Abstract: The optimization of the conversion of ginseng saponin glycosides to 20(S)-ginsenoside Rg(3) by enzymatic transformation was carried out using response surface methodology (RSM) based on a 2(3) factorial central composite design. The production of 20(S)- ... ...

    Abstract The optimization of the conversion of ginseng saponin glycosides to 20(S)-ginsenoside Rg(3) by enzymatic transformation was carried out using response surface methodology (RSM) based on a 2(3) factorial central composite design. The production of 20(S)-ginsenoside Rg(3) using several commercial enzymes indicated that the enzyme Cellulase-12T was the most efficient at producing 20(S)-ginsenoside Rg(3). To optimize the enzymatic production of 20(S)-ginsenoside Rg(3), response surface methodology was applied to determine the ideal amount of white ginseng extract, Cellulase-12T and reaction time. These results indicate that white ginseng extract (1.67%) treated with Celluase-12T (3.67%) for 72 hours had 4 times the quantity of 20(S)-ginsenoside Rg(3) compared to commercial white ginseng extract.
    MeSH term(s) Biotechnology/methods ; Cellulase/metabolism ; Chromatography, High Pressure Liquid ; Ginsenosides/biosynthesis ; Ginsenosides/chemistry ; Least-Squares Analysis ; Panax/chemistry ; Plant Extracts/metabolism ; Regression Analysis ; Spectrometry, Mass, Electrospray Ionization ; Time Factors
    Chemical Substances Ginsenosides ; Plant Extracts ; ginsenoside Rg3 (227D367Y57) ; Cellulase (EC 3.2.1.4)
    Language English
    Publishing date 2009-10-31
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2400836-9
    ISSN 1876-4347 ; 1871-6784
    ISSN (online) 1876-4347
    ISSN 1871-6784
    DOI 10.1016/j.nbt.2009.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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