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Article ; Online: Clinical Efficacy of 1% CHX Gluconate Gel and 0.12% CHX Solution: A Randomized Controlled Trial.

Lee, Su-Young / Nam, Eun-Joo

International journal of environmental research and public health

2022 Volume 19, Issue 15

Abstract: Chlorhexidine (CHX) is an effective antibacterial agent and is used in dental treatment in several formulations. The aim of this study was to compare the effectiveness of CHX solution and CHX gel on dental plaque inhibition and gingivitis relief by a ... ...

Abstract	Chlorhexidine (CHX) is an effective antibacterial agent and is used in dental treatment in several formulations. The aim of this study was to compare the effectiveness of CHX solution and CHX gel on dental plaque inhibition and gingivitis relief by a randomized clinical trial. Thirty-eight participants were randomly divided into two groups: control group (0.12% CHX solution) and test group (1% CHX gel). Participants were provided with CHX products and were instructed to use each product in the morning and evening for 1 week. Clinical results were evaluated by analyzing the collected data of Turesky et al. the modified Quigley-Hein Plaque Index (TQHPI), gingival index (GI) and the BANA test. Measurements were conducted 4 weeks and 8 weeks after using chlorhexidine products. The results were analyzed using repeated measured ANOVA and paired t-test. TQHPI and GI were significantly different after treatments in both groups (p < 0.001). The GI decreased more in the test group compared to the control group 4 weeks and 8 weeks later. In both groups, the BANA score also significantly decreased (p < 0.001) after 8 weeks, though the BANA score decreased relatively more in the CHX gel group than the CHX solution group. These results suggest that 1% CHX gel is more effective in reducing gingivitis and bacteria of periodontal disease than the 0.12% CHX solution. Therefore, the 1% CHX gel is expected to be actively used for non-surgical treatment of periodontal disease patients.
MeSH term(s)	Anti-Infective Agents, Local/therapeutic use ; Chlorhexidine/therapeutic use ; Gingivitis/drug therapy ; Gingivitis/prevention & control ; Gluconates ; Humans ; Mouthwashes/therapeutic use ; Treatment Outcome
Chemical Substances	Anti-Infective Agents, Local ; Gluconates ; Mouthwashes ; Chlorhexidine (R4KO0DY52L)
Language	English
Publishing date	2022-07-30
Publishing country	Switzerland
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19159358
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Article ; Online: Associations between obstructive sleep apnea and dental pain and chewing discomfort in Korean adults: a nationwide cross-sectional study.

Lee, Jae-Hyun / Han, Kyungdo / Lee, Su Young

Scientific reports

2023 Volume 13, Issue 1, Page(s) 12768

Abstract: Obstructive sleep apnea (OSA) may be linked with oral health issues. This study evaluated the associations between OSA, dental pain, and chewing discomfort. Big data from a nationwide survey involving 6984 participants aged ≥ 40 years were analyzed. The ... ...

Abstract	Obstructive sleep apnea (OSA) may be linked with oral health issues. This study evaluated the associations between OSA, dental pain, and chewing discomfort. Big data from a nationwide survey involving 6984 participants aged ≥ 40 years were analyzed. The STOP-Bang questionnaire was used to assess the OSA risk, categorizing the participants into low-, intermediate-, and high-risk groups. The associations of OSA risk with dental pain and chewing discomfort were evaluated using multivariate logistic regression analyses (α = 0.05). Results revealed that 50.33%, 37.50%, and 12.17% of the population belonged to the low-, intermediate-, and high-risk groups, respectively. After adjusting for covariates, a significant association emerged between OSA risk and dental pain, with adjusted odds ratios (95% confidence intervals) of 1 (reference), 1.208 (1.003-1.455), and 1.472 (1.131-1.916) for the low-, intermediate-, and high-risk groups, respectively (p = 0.0156). The adjusted odds ratio for chewing discomfort in the high-risk OSA group was 1.307 (0.977-1.748), although not significantly different from that of the low-risk group (p > 0.05). A high risk of OSA was associated with 1.472-fold increased risk of dental pain compared to those at low risk, implicating OSA as a potential risk indicator of poor oral health.
MeSH term(s)	Adult ; Humans ; Cross-Sectional Studies ; Mastication ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Surveys and Questionnaires ; Republic of Korea/epidemiology ; Pain/complications
Language	English
Publishing date	2023-08-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-40055-2
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Article: Successful New Dental Implant Installation in a Healed Site of Medication-Related Osteonecrosis of the Jaw: A Case Report.

Lee, Ju-Young / Park, Je-Uk / Lee, Su Young

The Journal of oral implantology

2023 Volume 49, Issue 2, Page(s) 117–123

Abstract: The purpose of this case report was to present a rare clinical case of successful new dental implant installation in the site of previously healed medication-related osteonecrosis of the jaw (MRONJ). An 80-year-old female patient with history of oral ... ...

Abstract	The purpose of this case report was to present a rare clinical case of successful new dental implant installation in the site of previously healed medication-related osteonecrosis of the jaw (MRONJ). An 80-year-old female patient with history of oral bisphosphonate (BP) therapy presented with pain and swelling of gingiva in the right posterior mandible. One of the 3 implants placed 15 years ago in the right mandibular posterior area was removed 6 months before the visit to our hospital, which led to worsening of the symptoms. After clinical and radiographic examination, the patient was diagnosed with stage 2 MRONJ. Along with antibiotic therapy, the patient underwent surgical intervention via sequestrectomy and removal of the remaining 2 implants. Adequate soft and hard tissue healing without any complications and signs of recurrence was confirmed, and implant installation with simultaneous bone grafting and prosthesis fabrication were done in the explantation sites of MRONJ. By the 7-year follow-up, no implant failure has been observed, and installation of implants was successful in the previously healed MRONJ site. Dental implant installation is possible in a patient with history of failed implant due to MRONJ. However, a careful treatment planning is needed before implantation in a previously healed site of MRONJ to reduce the potential risks of MRONJ recurrence and implant failure.
MeSH term(s)	Female ; Humans ; Aged, 80 and over ; Dental Implants ; Bisphosphonate-Associated Osteonecrosis of the Jaw/diagnostic imaging ; Bisphosphonate-Associated Osteonecrosis of the Jaw/surgery ; Mandible ; Prosthesis Implantation/adverse effects ; Wound Healing ; Bone Density Conservation Agents/adverse effects ; Diphosphonates
Chemical Substances	Dental Implants ; Bone Density Conservation Agents ; Diphosphonates
Language	English
Publishing date	2023-04-06
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	448462-9
ISSN	1548-1336 ; 0160-6972
ISSN (online)	1548-1336
ISSN	0160-6972
DOI	10.1563/aaid-joi-D-20-00295
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Article ; Online: Activity of novel β-lactam/β-lactamase inhibitor combinations against serine carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa.

Lee, Su Young / Gill, Christian M / Nicolau, David P

The Journal of antimicrobial chemotherapy

2023 Volume 78, Issue 12, Page(s) 2795–2800

Abstract: Background: Antimicrobial resistance in Pseudomonas aeruginosa is complex and multifaceted. While the novel β-lactamase inhibitors (BLIs) avibactam, relebactam and vaborbactam inhibit serine-based β-lactamases, the comparative potency of the novel β- ... ...

Abstract	Background: Antimicrobial resistance in Pseudomonas aeruginosa is complex and multifaceted. While the novel β-lactamase inhibitors (BLIs) avibactam, relebactam and vaborbactam inhibit serine-based β-lactamases, the comparative potency of the novel β-lactam (BL)/BLI combinations against serine carbapenemase-producing P. aeruginosa is unknown. Objectives: To compare the in vitro activity of ceftazidime/avibactam, ceftazidime, imipenem/relebactam, imipenem, meropenem/vaborbactam and meropenem against serine β-lactamase-producing P. aeruginosa. Methods: Carbapenem-resistant P. aeruginosa were collated through the Enhancing Rational Antimicrobials against Carbapenem-resistant P. aeruginosa (ERACE-PA) Global Surveillance. Isolates positive for serine-based carbapenemases were assessed. MICs were determined by broth microdilution to each novel BL/BLI and BL alone. Results: GES was the most common carbapenemase identified (n = 59) followed by KPC (n = 8). Ceftazidime/avibactam had MIC50/MIC90 values of 4/8 mg/L and 91% of isolates were susceptible. Conversely, ceftazidime alone was active against only 3% of isolates. The MIC50/MIC90 of imipenem/relebactam were 16/>16 mg/L and 13% of all isolates were defined as susceptible. Of the KPC-producing isolates, 38% were susceptible to imipenem/relebactam, compared with 0% to imipenem. The meropenem/vaborbactam MIC50/MIC90 were >16/>16 mg/L, and 6% of isolates were susceptible, which was similar to meropenem alone (MIC50/90, >8/>8 mg/L; 3% susceptible) suggesting the addition of vaborbactam cannot overcome co-expressed, non-enzymatic resistance mechanisms. Conclusions: Among the novel BL/BLIs, ceftazidime/avibactam displayed better in vitro activity and thus is a rational treatment option for serine carbapenemase-harbouring P. aeruginosa. While imipenem/relebactam displayed some activity, particularly against isolates with blaKPC, meropenem/vaborbactam exhibited poor activity, with MICs similar to meropenem alone.
MeSH term(s)	Meropenem/pharmacology ; Ceftazidime/pharmacology ; Carbapenems/pharmacology ; beta-Lactamase Inhibitors/pharmacology ; Pseudomonas aeruginosa ; Lactams ; Azabicyclo Compounds/pharmacology ; Anti-Bacterial Agents/pharmacology ; beta-Lactamases ; Imipenem/pharmacology ; Drug Combinations ; Microbial Sensitivity Tests
Chemical Substances	relebactam (Y1MYA2UHFL) ; Meropenem (FV9J3JU8B1) ; Ceftazidime (9M416Z9QNR) ; Carbapenems ; carbapenemase (EC 3.5.2.6) ; beta-Lactamase Inhibitors ; avibactam (7352665165) ; vaborbactam (1C75676F8V) ; Lactams ; Azabicyclo Compounds ; Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6) ; Imipenem (71OTZ9ZE0A) ; Drug Combinations
Language	English
Publishing date	2023-02-25
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	191709-2
ISSN	1460-2091 ; 0305-7453
ISSN (online)	1460-2091
ISSN	0305-7453
DOI	10.1093/jac/dkad225
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Zs.A 1197: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Effect of dental caries management using 'CAMBRA-kids' mobile application for children under 5 years old.

Yeo, An-Na / Lee, Su-Young

International journal of dental hygiene

2021 Volume 20, Issue 3, Page(s) 443–452

Abstract: Objective: To determine effects of dental caries management using 'CAMBRA-kids' mobile application for children under 5 years old for a period of a year.: Methods: This study was conducted on 119 preschoolers and parents. Parents downloaded 'CAMBRA- ... ...

Abstract	Objective: To determine effects of dental caries management using 'CAMBRA-kids' mobile application for children under 5 years old for a period of a year. Methods: This study was conducted on 119 preschoolers and parents. Parents downloaded 'CAMBRA-kids' mobile application and entered risk factors and protective factors for children. Clinician entered disease indicators after clinical examination of children. Based on the input, the caries risk group was automatically determined by the 'CAMBRA-kids' application. According to the caries risk level, caries management was conducted for 12 months according to guidelines. Results: Children's caries risk level changed after conducting caries management for 1 year. In the change of CRA (Caries risk assessment) by factor, risk factors decreased in all risk groups, whereas protective factors increased in all risk groups. Disease indicators increased after 12 months in the extreme high-risk group and the high-risk group, but decreased in the low-risk group. Conclusion: This study evaluated the effect of systematic dental caries management using 'CAMBRA-kids' mobile application for preschool children. As a result, dental caries management had effects on children, especially for the extreme high-risk group and the high-risk group. Thus, it is expected to be used in a variety of areas for caries management of preschoolers.
MeSH term(s)	Child, Preschool ; Dental Caries/etiology ; Dental Caries/prevention & control ; Dental Caries Susceptibility ; Humans ; Mobile Applications ; Risk Assessment ; Risk Factors
Language	English
Publishing date	2021-12-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2252118-5
ISSN	1601-5037 ; 1601-5029
ISSN (online)	1601-5037
ISSN	1601-5029
DOI	10.1111/idh.12565
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Zs.A 6768: Show issues

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Article ; Online: Accuracy of Impression Techniques for Dental Implants Placed in Five Different Orientations.

Kim, Hyo-Seon / Lee, Jae-Hyun / Lee, Su Young

The International journal of oral & maxillofacial implants

2022 Volume 37, Issue 5, Page(s) 997–1002

Abstract: Purpose: The purpose of this study was to evaluate the impression accuracy of two implants placed in different orientations and compare the impression accuracy obtained with the dual-arch impression technique using hybrid impression copings and the ... ...

Abstract	Purpose: The purpose of this study was to evaluate the impression accuracy of two implants placed in different orientations and compare the impression accuracy obtained with the dual-arch impression technique using hybrid impression copings and the conventional open-tray impression technique. Materials and methods: Five mandibular dentiform models were prepared by placing implants in the second premolar and second molar regions in the following different orientations: parallel to each other; 15-degree mesiodistal angulation; 30-degree mesiodistal angulation; 15-degree buccolingual angulation; and 30-degree buccolingual angulation. After making 10 impressions for each model with the open-tray impression technique and dual-arch impression technique with hybrid impression copings, cast models were fabricated for each impression (n = 10). Scan bodies were mounted on the five dentiform models and the fabricated 100 cast models were scanned using a desktop scanner. The three-dimensional deviation of the scan bodies on the cast models was calculated and compared to the reference data from the dentiform models. A two-way analysis of variance was conducted (α = .05). Results: The root mean square deviation values obtained from the implants placed with 30-degree mesiodistal angulation were 93.05 ± 6.21 μm with the open-tray impression technique and 104.01 ± 8.89 μm with the dual-arch impression technique, which were the largest deviation values for both techniques (P < .001). Compared to the open-tray impression technique, the dual-arch impression technique with the hybrid impression copings showed significantly lower accuracy when the angulation between the implants was 15 degrees mesiodistally (P < .001), 30 degrees mesiodistally (P = .016), or 30 degrees buccolingually (P < .001). However, there was no significant difference between the accuracy of the two impression techniques for parallel implants (P = .74). Conclusion: When the two implants were inclined 30 degrees mesiodistally, both implant impression techniques showed the largest deviation and the dual-arch impression technique showed lower accuracy compared to the conventional open-tray impression technique. Parallel placement of implants may improve impression accuracy and enable use of the dual-arch impression technique.
MeSH term(s)	Dental Implants ; Dental Impression Materials ; Dental Impression Technique ; Models, Dental
Chemical Substances	Dental Implants ; Dental Impression Materials
Language	English
Publishing date	2022-09-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	632880-5
ISSN	1942-4434 ; 0882-2786
ISSN (online)	1942-4434
ISSN	0882-2786
DOI	10.11607/jomi.9441
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Article ; Online: Application of CAD in Landscape Grid Space Design and Drawing.

Qiao, Shuang / Liu, Yanbin / Lee, SuYoung

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 5800183

Abstract: CAD technology has brought great convenience and effect to the design. This paper proposes to update the comparative analysis of the basic classical landscape grid space structure by constructing a landscape grid space design. According to the actual ... ...

Abstract	CAD technology has brought great convenience and effect to the design. This paper proposes to update the comparative analysis of the basic classical landscape grid space structure by constructing a landscape grid space design. According to the actual situation of domestic landscape grid space design and drawing, this paper highlights the role of CAD technology in landscape grid space design and drawing and provides an important basis for the subsequent application of CAD software in landscape grid space design.
MeSH term(s)	Computer Systems ; Software
Language	English
Publishing date	2022-04-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/5800183
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Article: Cognitive impairments in patients with subacute coronavirus disease: Initial experiences in a post-coronavirus disease clinic.

Chang, Jhin Goo / Ha, Eun-Hye / Lee, Wangjun / Lee, Su Young

Frontiers in aging neuroscience

2022 Volume 14, Page(s) 994331

Abstract: Background: A significant number of patients experience persistent cognitive impairment after coronavirus disease (COVID-19). This study aimed to investigate the cognitive function of patients in the subacute phase of COVID-19 and to identify the ... ...

Abstract	Background: A significant number of patients experience persistent cognitive impairment after coronavirus disease (COVID-19). This study aimed to investigate the cognitive function of patients in the subacute phase of COVID-19 and to identify the clinical factors associated with cognitive sequelae. Materials and methods: Data from patients who visited the psychiatric department of our post-COVID clinic between March and May 2022 were analyzed. The results of neuropsychiatric function tests, including the digit span forward (attention/processing speed) and backward (working memory) tests, the trail making test part A (attention/processing speed) and part B (executive functioning), and the Stroop word color interference test (executive functioning), as well as clinical data from 40 patients in the subacute phase of COVID-19 were analyzed. We calculated the frequency of impairments in each cognitive measure, defined as a z-score of ≤-1.5 standard deviations below measure-specific age- and sex-adjusted norms. Results: Of the participants, 72.5% ( Conclusion: Regular examination of cognitive function is needed, especially in elderly individuals, regardless of the subjective symptom manifestations.
Language	English
Publishing date	2022-11-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2558898-9
ISSN	1663-4365
ISSN	1663-4365
DOI	10.3389/fnagi.2022.994331
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Article ; Online: Trueness of digital implant impressions based on implant angulation and scan body materials.

Lee, Jae-Hyun / Bae, Jae-Hwi / Lee, Su Young

Scientific reports

2021 Volume 11, Issue 1, Page(s) 21892

Abstract: Effects of implant angulation on digital implant impression accuracy remain controversial. Therefore, this in vitro study aimed to compare the digital implant impression trueness among models with different implant angulations and scan body materials. ... ...

Abstract	Effects of implant angulation on digital implant impression accuracy remain controversial. Therefore, this in vitro study aimed to compare the digital implant impression trueness among models with different implant angulations and scan body materials. Six partially edentulous mandibular models with dental implants on the right second premolar and second molar areas were categorized according to the implant angulation of the distal implant (parallel, or 15° mesially or lingually tilted compared to the mesial implant) and scan body materials (polyetheretherketone or titanium). After scanning each model with intraoral scanners, the root mean square and within-tolerance values were calculated with respect to the reference, and nonparametric statistical tests were performed (α = .05). Scan data from models with the mesially tilted distal implant showed better trueness than the corresponding parallel and lingually tilted groups in terms of root mean square values (p < .017). The root mean square value in the titanium scan body group was lower than that in the polyetheretherketone scan body group (p < .001). However, the percentage within a tolerance of ± .1 mm was higher in the polyetheretherketone scan body group than in the titanium scan body group (p = .001). Intraoral scan data of models where the terminal implant was mesially tilted showed better trueness.
Language	English
Publishing date	2021-11-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-01442-9
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Article: Finite Element Analysis of Dental Implants with Zirconia Crown Restorations: Conventional Cement-Retained vs. Cementless Screw-Retained.

Lee, Jae-Hyun / Jang, Ho Yeol / Lee, Su Young

Materials (Basel, Switzerland)

2021 Volume 14, Issue 10

Abstract: The present study was designed to compare the stress distributions in two restoration types of implants and the surrounding bone. The first restoration type was a conventional cement-retained zirconia crown, and the second was a novel cementless screw- ... ...

Abstract	The present study was designed to compare the stress distributions in two restoration types of implants and the surrounding bone. The first restoration type was a conventional cement-retained zirconia crown, and the second was a novel cementless screw-retained zirconia crown with a base abutment. A three-dimensional finite element method was used to model the implants, restorations, and supporting bone. A comparative study of the two implants was performed under two masticatory loads: a vertical load of 100 N and a 30-degree oblique load of 100 N. Under both loading conditions, the maximum von Mises stress and strain values in the implant and supporting bone were higher in the conventional cement-retained restoration model than in the cementless screw-retained model. In terms of stress distribution, the cementless screw-retained zirconia crown with base abutment may be considered a superior restoration option compared to the conventional cement-retained zirconia crown.
Language	English
Publishing date	2021-05-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma14102666
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