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  1. Artikel ; Online: Triage and length of stay in emergency department visits due to alcohol intoxication: A retrospective chart review.

    Lee, Sunmi / Oh, Hyunjin

    Australasian emergency care

    2022  Band 26, Heft 1, Seite(n) 90–95

    Abstract: Background: Patients with alcohol intoxication are screened and treated at emergency departments (EDs), at the cost of alcohol-related ED visit resource consumption. The purposes of this study were to identify characteristics of patients with alcohol ... ...

    Abstract Background: Patients with alcohol intoxication are screened and treated at emergency departments (EDs), at the cost of alcohol-related ED visit resource consumption. The purposes of this study were to identify characteristics of patients with alcohol intoxication, in terms of triage, blood alcohol concentration (BAC), and ED length of stay (LOS) and to compare these characteristics by homelessness status.
    Methods: We conducted a retrospective chart review of all visits and referrals to one drunken center in an ED between January and December 2019. Adults aged over 18 years admitted to the drunken center with a blood alcohol concentration (BAC) of 100 mg/dl or higher were included.
    Results: Approximately 89 % were male, around 30.4 % of the patients with acute alcohol intoxication were homeless. Approximately 46 % of patients were Medicaid or non-insured. Approximately 74.2 % of the patients were classified as KTAS 4 (less urgent) and 5 (nonurgency) upon initial KTAS evaluation. Both BAC and ED LOS were significantly higher in the homeless group.
    Conclusions: About half of alcohol intoxicated patients who visited ED were vulnerable, and they visited the ED due to the problem of less urgent or non-urgent status of triage. Sobering places, not ED, and connecting patients with social work programs is important.
    Mesh-Begriff(e) Adult ; United States ; Humans ; Male ; Middle Aged ; Female ; Length of Stay ; Alcoholic Intoxication/complications ; Alcoholic Intoxication/epidemiology ; Alcoholic Intoxication/therapy ; Blood Alcohol Content ; Triage ; Retrospective Studies ; Emergency Service, Hospital
    Chemische Substanzen Blood Alcohol Content
    Sprache Englisch
    Erscheinungsdatum 2022-08-24
    Erscheinungsland Australia
    Dokumenttyp Journal Article
    ISSN 2588-994X
    ISSN (online) 2588-994X
    DOI 10.1016/j.auec.2022.08.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Age-specific risk factors for the prediction of obesity using a machine learning approach.

    Jeon, Junhwi / Lee, Sunmi / Oh, Chunyoung

    Frontiers in public health

    2023  Band 10, Seite(n) 998782

    Abstract: Machine Learning is a powerful tool to discover hidden information and relationships in various data-driven research fields. Obesity is an extremely complex topic, involving biological, physiological, psychological, and environmental factors. One ... ...

    Abstract Machine Learning is a powerful tool to discover hidden information and relationships in various data-driven research fields. Obesity is an extremely complex topic, involving biological, physiological, psychological, and environmental factors. One successful approach to the topic is machine learning frameworks, which can reveal complex and essential risk factors of obesity. Over the last two decades, the obese population (BMI of above 23) in Korea has grown. The purpose of this study is to identify risk factors that predict obesity using machine learning classifiers and identify the algorithm with the best accuracy among classifiers used for obesity prediction. This work will allow people to assess obesity risk from blood tests and blood pressure data based on the KNHANES, which used data constructed by the annual survey. Our data include a total of 21,100 participants (male 10,000 and female 11,100). We assess obesity prediction by utilizing six machine learning algorithms. We explore age- and gender-specific risk factors of obesity for adults (19-79 years old). Our results highlight the four most significant features in all age-gender groups for predicting obesity: triglycerides, ALT (SGPT), glycated hemoglobin, and uric acid. Our findings show that the risk factors for obesity are sensitive to age and gender under different machine learning algorithms. Performance is highest for the 19-39 age group of both genders, with over 70% accuracy and AUC, while the 60-79 age group shows around 65% accuracy and AUC. For the 40-59 age groups, the proposed algorithm achieved over 70% in AUC, but for the female participants, it achieved lower than 70% accuracy. For all classifiers and age groups, there is no big difference in the accuracy ratio when the number of features is more than six; however, the accuracy ratio decreased in the female 19-39 age group.
    Mesh-Begriff(e) Adult ; Humans ; Male ; Female ; Young Adult ; Middle Aged ; Aged ; Obesity/epidemiology ; Machine Learning ; Risk Factors ; Algorithms ; Age Factors
    Sprache Englisch
    Erscheinungsdatum 2023-01-17
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.998782
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Influences of Momentum Ratio on Transverse Dispersion for Intermediate-Field Mixing Downstream of Channel Confluence.

    Shin, Jaehyun / Lee, Sunmi / Park, Inhwan

    International journal of environmental research and public health

    2023  Band 20, Heft 4

    Abstract: This study aims to analyze the influences of momentum ratio ( ...

    Abstract This study aims to analyze the influences of momentum ratio (
    Mesh-Begriff(e) Computer Simulation ; Water Pollution ; Motion ; Hydrodynamics
    Sprache Englisch
    Erscheinungsdatum 2023-02-04
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20042776
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Occurrence of and dermal exposure to benzene, toluene and styrene in sunscreen products marketed in the United States.

    Pal, Vineet Kumar / Lee, Sunmi / Kannan, Kurunthachalam

    The Science of the total environment

    2023  Band 888, Seite(n) 164196

    Abstract: Occurrence of volatile organic compounds (VOCs) such as benzene in personal care products is a topic of public health concern. Sunscreen products are extensively used to protect skin and hair from UV radiation from sun light. Nevertheless, little is ... ...

    Abstract Occurrence of volatile organic compounds (VOCs) such as benzene in personal care products is a topic of public health concern. Sunscreen products are extensively used to protect skin and hair from UV radiation from sun light. Nevertheless, little is known about exposure doses and risks of VOCs present in sunscreens. In this study, we determined the concentrations of and exposure to three VOCs, namely benzene, toluene and styrene, in 50 sunscreen products marketed in the United States. Benzene, toluene and styrene were found in 80 %, 92 % and 58 %, respectively, of the samples analyzed at mean concentrations of 45.8 ng/g (range: 0.007-862), 89.0 ng/g (range: 0.006-470) and 161 ng/g (range: 0.006-1650), respectively. The mean dermal exposure doses (DEDs) to benzene, toluene and styrene of children/teenagers were 68.3, 133 and 441 ng/kg-bw/d, respectively, whereas those of adults were 48.7, 94.6 and 171 ng/kg-bw/d, respectively. The lifetime cancer risk from benzene concentrations present in 22 sunscreen products (44 % of the samples) for children/teenagers and 19 sunscreen products (38 %) for adults, exceeded the acceptable benchmark risk level (1.0 × 10
    Mesh-Begriff(e) Adult ; Child ; Adolescent ; United States ; Humans ; Toluene/analysis ; Benzene/analysis ; Sunscreening Agents ; Styrene ; Benzene Derivatives/analysis ; Volatile Organic Compounds/analysis ; Air Pollutants/analysis
    Chemische Substanzen Toluene (3FPU23BG52) ; Benzene (J64922108F) ; Sunscreening Agents ; Styrene (44LJ2U959V) ; Benzene Derivatives ; Volatile Organic Compounds ; Air Pollutants
    Sprache Englisch
    Erscheinungsdatum 2023-05-17
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.164196
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Heterogeneity is a key factor describing the initial outbreak of COVID-19.

    Kim, Sungchan / Abdulali, Arsen / Lee, Sunmi

    Applied mathematical modelling

    2023  Band 117, Seite(n) 714–725

    Abstract: Assessing the transmission potential of emerging infectious diseases, such as COVID-19, is crucial for implementing prompt and effective intervention policies. The basic reproduction number is widely used to measure the severity of the early stages of ... ...

    Abstract Assessing the transmission potential of emerging infectious diseases, such as COVID-19, is crucial for implementing prompt and effective intervention policies. The basic reproduction number is widely used to measure the severity of the early stages of disease outbreaks. The basic reproduction number of standard ordinary differential equation models is computed for homogeneous contact patterns; however, realistic contact patterns are far from homogeneous, specifically during the early stages of disease transmission. Heterogeneity of contact patterns can lead to superspreading events that show a significantly high level of heterogeneity in generating secondary infections. This is primarily due to the large variance in the contact patterns of complex human behaviours. Hence, in this work, we investigate the impacts of heterogeneity in contact patterns on the basic reproduction number by developing two distinct model frameworks: 1) an SEIR-Erlang ordinary differential equation model and 2) an SEIR stochastic agent-based model. Furthermore, we estimated the transmission probability of both models in the context of COVID-19 in South Korea. Our results highlighted the importance of heterogeneity in contact patterns and indicated that there should be more information than one quantity (the basic reproduction number as the mean quantity), such as a degree-specific basic reproduction number in the distributional sense when the contact pattern is highly heterogeneous.
    Sprache Englisch
    Erscheinungsdatum 2023-01-09
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2004151-2
    ISSN 0307-904X
    ISSN 0307-904X
    DOI 10.1016/j.apm.2023.01.005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Personality of Public Health Organizations' Instagram Accounts and According Differences in Photos at Content and Pixel Levels.

    Kim, Yunhwan / Lee, Sunmi

    International journal of environmental research and public health

    2021  Band 18, Heft 8

    Abstract: Organizations maintain social media accounts and upload posts to show their activities and communicate with the public, as individual users do. Thus, organizations' social media accounts can be examined from the same perspective of that of individual ... ...

    Abstract Organizations maintain social media accounts and upload posts to show their activities and communicate with the public, as individual users do. Thus, organizations' social media accounts can be examined from the same perspective of that of individual users' accounts, with personality being one of the perspectives. In line with previous studies that analyzed the personality of non-human objects such as products, stores, brands, and websites, this study analyzed the personality of Instagram accounts of public health organizations. It also extracted features at content and pixel levels from the photos uploaded on the organizations' accounts and examined how they were related to the personality traits of the accounts. The results suggested that the personality of public health organizations can be summarized as being high in openness and agreeableness but lower in extraversion and neuroticism. Openness and agreeableness were the personality traits associated the most with the content-level features, while extraversion and neuroticism were the ones associated the most with the pixel-level features. In addition, for each of the two traits associated the most with either the content- or pixel- level features, their associations tended to be in opposite directions with one another. The personality traits, except for neuroticism, were predicted from the photo features with an acceptable level of accuracy.
    Mesh-Begriff(e) Extraversion, Psychological ; Humans ; Personality ; Personality Disorders ; Personality Inventory ; Public Health
    Sprache Englisch
    Erscheinungsdatum 2021-04-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph18083903
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Variability in the serial interval of COVID-19 in South Korea: a comprehensive analysis of age and regional influences.

    Lee, Hyosun / Lee, Gira / Kim, Tobhin / Kim, Suhyeon / Kim, Hyoeun / Lee, Sunmi

    Frontiers in public health

    2024  Band 12, Seite(n) 1362909

    Abstract: Introduction: Quantifying the transmissibility over time, particularly by region and age, using parameters such as serial interval and time-varying reproduction number, helps in formulating targeted interventions. Moreover, considering the impact of ... ...

    Abstract Introduction: Quantifying the transmissibility over time, particularly by region and age, using parameters such as serial interval and time-varying reproduction number, helps in formulating targeted interventions. Moreover, considering the impact of geographical factors on transmission provides valuable insights into the effectiveness of control measures.
    Methods: Drawing on a comprehensive dataset of COVID-19 cases in South Korea, we analyzed transmission dynamics with a focus on age and regional variations. The dataset, compiled through the efforts of dedicated epidemiologists, includes information on symptom onset dates, enabling detailed investigations. The pandemic was divided into distinct phases, aligning with changes in policies, emergence of variants, and vaccination efforts. We analyzed various interventions such as social distancing, vaccination rates, school closures, and population density. Key parameters like serial interval, heatmaps, and time-varying reproduction numbers were used to quantify age and region-specific transmission trends.
    Results: Analysis of transmission pairs within age groups highlighted the significant impact of school closure policies on the spread among individuals aged 0-19. This analysis also shed light on transmission dynamics within familial and educational settings. Changes in confirmed cases over time revealed a decrease in spread among individuals aged 65 and older, attributed to higher vaccination rates. Conversely, densely populated metropolitan areas experienced an increase in confirmed cases. Examination of time-varying reproduction numbers by region uncovered heterogeneity in transmission patterns, with regions implementing strict social distancing measures showing both increased confirmed cases and delayed spread, indicating the effectiveness of these policies.
    Discussion: Our findings underscore the importance of evaluating and tailoring epidemic control policies based on key COVID-19 parameters. The analysis of social distancing measures, school closures, and vaccine impact provides valuable insights into controlling transmission. By quantifying the impact of these interventions on different age groups and regions, we contribute to the ongoing efforts to combat the COVID-19 pandemic effectively.
    Mesh-Begriff(e) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; Pandemics/prevention & control ; SARS-CoV-2 ; Republic of Korea/epidemiology ; Policy
    Sprache Englisch
    Erscheinungsdatum 2024-03-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1362909
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Unraveling the Intricacies of Autophagy and Mitophagy: Implications in Cancer Biology.

    Lee, Sunmi / Son, Ji-Yoon / Lee, Jinkyung / Cheong, Heesun

    Cells

    2023  Band 12, Heft 23

    Abstract: Autophagy is an essential lysosome-mediated degradation pathway that maintains cellular homeostasis and viability in response to various intra- and extracellular stresses. Mitophagy is a type of autophagy that is involved in the intricate removal of ... ...

    Abstract Autophagy is an essential lysosome-mediated degradation pathway that maintains cellular homeostasis and viability in response to various intra- and extracellular stresses. Mitophagy is a type of autophagy that is involved in the intricate removal of dysfunctional mitochondria during conditions of metabolic stress. In this review, we describe the multifaceted roles of autophagy and mitophagy in normal physiology and the field of cancer biology. Autophagy and mitophagy exhibit dual context-dependent roles in cancer development, acting as tumor suppressors and promoters. We also discuss the important role of autophagy and mitophagy within the cancer microenvironment and how autophagy and mitophagy influence tumor host-cell interactions to overcome metabolic deficiencies and sustain the activity of cancer-associated fibroblasts (CAFs) in a stromal environment. Finally, we explore the dynamic interplay between autophagy and the immune response in tumors, indicating their potential as immunomodulatory targets in cancer therapy. As the field of autophagy and mitophagy continues to evolve, this comprehensive review provides insights into their important roles in cancer and cancer microenvironment.
    Mesh-Begriff(e) Humans ; Mitophagy/physiology ; Autophagy/physiology ; Neoplasms/pathology ; Biology ; Tumor Microenvironment
    Sprache Englisch
    Erscheinungsdatum 2023-11-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12232742
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Enhanced adhesion of functional layers by controlled electrografting of ethylenediamine on ITO for electrochemical immunoassay in microfluidic channel.

    Lee, Sunmi / Lee, Haeyeon / Yeon, Song Yi / Chung, Taek Dong

    Biosensors & bioelectronics

    2023  Band 229, Seite(n) 115201

    Abstract: Two-electrode (2E) system of the interdigitated electrode array (IDA), which operates neither reference nor counter electrodes, has great potential to miniaturize multiplex immunoassay in a microfluidic chip for point-of-care testing. However, it is ... ...

    Abstract Two-electrode (2E) system of the interdigitated electrode array (IDA), which operates neither reference nor counter electrodes, has great potential to miniaturize multiplex immunoassay in a microfluidic chip for point-of-care testing. However, it is necessary to firmly immobilize the mediator layer on IDA made of indium tin oxide (ITO) which is chemically inert. It is important because the mediator determines the electrochemical potential in the 2E system, but the layer is easy to be detached during the washing processes of immunoassay. Here, we controlled the concentration of ethylenediamine (EDA) to generate a permeable and robust film to adhere to mediators on the ITO IDA chip. Electrooxidation of EDA yielded thin oligomeric ethyleneimine (OEI) film and it provided amine groups for immobilizing the mediator, poly(toluidine blue) (pTB), via common conjugation reaction. Despite repeated flows in the microchannel, which are essential for sensitive immunoassay, the pTB/OEI layer was hardly washed and still remained on the ITO IDA. Myoglobin was measured down to ∼ pg/mL level. Therefore, the ITO IDA modified with the OEI film in the 2E system constituted a stable platform that withstands washing steps for sensitive electrochemical detection in the miniaturized immunoassay.
    Mesh-Begriff(e) Microfluidics ; Biosensing Techniques ; Tin Compounds ; Immunoassay ; Electrodes ; Ethylenediamines
    Chemische Substanzen indium tin oxide (71243-84-0) ; Tin Compounds ; Ethylenediamines
    Sprache Englisch
    Erscheinungsdatum 2023-03-09
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2023.115201
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Uncovering COVID-19 Transmission Tree: Identifying Traced and Untraced Infections in an Infection Network

    Lee, Hyunwoo / Choi, Hayoung / Lee, Hyojung / Lee, Sunmi / Kim, Changhoon

    medRxiv

    Abstract: We present a comprehensive analysis of COVID19 transmission dynamics using an infection network derived from epidemiological data in South Korea, covering the period from January 3, 2020, to July 11, 2021. This network, illustrating infector infectee ... ...

    Abstract We present a comprehensive analysis of COVID19 transmission dynamics using an infection network derived from epidemiological data in South Korea, covering the period from January 3, 2020, to July 11, 2021. This network, illustrating infector infectee relationships, provides invaluable insights for managing and mitigating the spread of the disease. However, significant missing data hinder the conventional analysis of such networks from epidemiological surveillance. To address this challenge, our research suggests a novel approach for categorizing individuals into four distinct groups, based on the classification of their infector or infectee status as either traced or untraced cases among all confirmed cases. Furthermore, the study analyzes the changes in the infection networks among untraced and traced cases across five distinct periods. The four types of cases emphasize the impact of various factors, such as the implementation of public health strategies and the emergence of novel COVID19 variants, which contribute to the propagation of COVID19 transmission. One of the key findings of this study is the identification of notable transmission patterns in specific age groups, particularly in those aged 20 to 29, 40 to 69, and 09, based on the four type classifications. Moreover, we develop a novel real time indicator to assess the potential for infectious disease transmission more effectively. By analyzing the lengths of connected components, this indicator facilitates improved predictions and enables policymakers to proactively respond, thereby helping to mitigate the effects of the pandemic on global communities.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2024-05-03
    Verlag Cold Spring Harbor Laboratory Press
    Dokumenttyp Artikel ; Online
    DOI 10.1101/2024.05.01.24306730
    Datenquelle COVID19

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