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  1. Article: Factors influencing pharmacists and pharmaceutical scientists' membership in professional organisations: an international survey.

    Sullivan, Louisa / Ho, Jun Ni / Lee, You Zhuan / Khalid, Garba Mohammed / Sandhu, Anisha Kaur / Meilianti, Sherly / Aqqad, Farah / Lim, Renly

    Journal of pharmaceutical policy and practice

    2023  Volume 16, Issue 1, Page(s) 105

    Abstract: Background: Professional organisations exist as international or national organisations, with each country establishing at least one national professional association. There remains a knowledge gap about factors that influence professional ... ...

    Abstract Background: Professional organisations exist as international or national organisations, with each country establishing at least one national professional association. There remains a knowledge gap about factors that influence professional organisational involvement of pharmacists and pharmaceutical scientists. This study aims to explore the motivators and barriers of pharmacy professionals holding organisation membership from a global perspective.
    Methods: An online questionnaire was developed and disseminated between May and July 2021. The survey was open to all pharmacists and pharmaceutical scientists. The survey consisted of four sections; demographic information, questions about professional organisations, about the International Pharmaceutical Federation (FIP) and its impact on the members. Data were analysed descriptively.
    Results: A total of 1033 complete survey responses were received and included in the analysis. Of all respondents, 761 (73.7%) respondents were current members of a professional organisation and 272 (26.3%) were not members of any professional organisation. Overall, findings demonstrated networking, education, training and professional development opportunities as the main interests and anticipated activities, while the lack of clarity or need to join organisation, time, and financial constraints as the main barriers of pharmacy professionals holding membership. The majority of FIP members are satisfied with current FIP activities, and anticipate further networking opportunities, educational resources and grants made available to members.
    Conclusions: Understanding the perceptions and needs, as well as factors that influence engagement of pharmacists and pharmaceutical scientists is the key to enhancing membership. Professional organisations are highly encouraged to strengthen and target activities according to the identified motivators and barriers.
    Language English
    Publishing date 2023-09-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2734772-2
    ISSN 2052-3211
    ISSN 2052-3211
    DOI 10.1186/s40545-023-00620-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Formulation and In Vivo Evaluation of a Solid Self-Emulsifying Drug Delivery System Using Oily Liquid Tocotrienols as Model Active Substance.

    Lee, You Zhuan / Seow, Eng Kwong / Lim, Sheau Chin / Yuen, Kah Hay / Abdul Karim Khan, Nurzalina

    Pharmaceutics

    2021  Volume 13, Issue 11

    Abstract: Self-emulsifying drug delivery systems (SEDDS) can improve the oral bioavailability of poorly water-soluble drugs. Solid self-emulsifying drug delivery systems (s-SEDDS) offer several advantages including improved drug stability, ease of administration, ... ...

    Abstract Self-emulsifying drug delivery systems (SEDDS) can improve the oral bioavailability of poorly water-soluble drugs. Solid self-emulsifying drug delivery systems (s-SEDDS) offer several advantages including improved drug stability, ease of administration, and production. Most compounds employed in developing s-SEDDS are solid in nature, with a high amount of surfactants added. The aim of this study was to develop an s-SEDDS using a tocotrienol-rich fraction (TRF) as the model liquid active substance via a simple adsorption method. The solid formulation was developed using magnesium aluminosilicate as the carrier with 70% TRF and 30% surfactants (poloxamer and Labrasol
    Language English
    Publishing date 2021-10-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics13111777
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pharmacokinetic and anti-colon cancer properties of curcumin-containing chitosan-pectinate composite nanoparticles.

    Alkhader, Enas / Roberts, Clive J / Rosli, Rozita / Yuen, Kah Hay / Seow, Eng Kwong / Lee, You Zhuan / Billa, Nashiru

    Journal of biomaterials science. Polymer edition

    2018  Volume 29, Issue 18, Page(s) 2281–2298

    Abstract: Curcumin, the active ingredient of the rhizome curcuma longa has been extensively studied as an anticancer agent for various types of tumours. However, its efficacy as an anticancer agent is restricted due to poor absorption from the gastrointestinal ... ...

    Abstract Curcumin, the active ingredient of the rhizome curcuma longa has been extensively studied as an anticancer agent for various types of tumours. However, its efficacy as an anticancer agent is restricted due to poor absorption from the gastrointestinal tract, rapid metabolism and degradation in acidic medium. In the present study, we encapsulated curcumin in chitosan-pectinate nanoparticulate system (CUR-CS-PEC-NPs) for deployment of curcumin to the colon, whereby curcumin is protected against degradative effects in the upper digestive tract, and hence, maintaining its anticancer properties until colon arrival. The CUR-CS-PEC-NPs was taken up by HT-29 colorectal cancer cells which ultimately resulted in a significant reduction in cancer cell propagation. The anti-proliferative effect of the encapsulated curcumin was similar to that of free curcumin at equivalent doses which confirms that the encapsulation process did not impede the anticancer activity of curcumin. The oral bioavailability (C
    MeSH term(s) Animals ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Line ; Cell Survival/drug effects ; Chitosan/chemistry ; Colonic Neoplasms/drug therapy ; Curcumin/pharmacokinetics ; Curcumin/pharmacology ; Drug Carriers ; Drug Liberation ; Drug Stability ; Humans ; Male ; Nanoparticles/chemistry ; Pectins/chemistry ; Rats, Sprague-Dawley
    Chemical Substances Antineoplastic Agents ; Drug Carriers ; Pectins (89NA02M4RX) ; Chitosan (9012-76-4) ; Curcumin (IT942ZTH98)
    Language English
    Publishing date 2018-12-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1014190-x
    ISSN 1568-5624 ; 1568-5616 ; 0920-5063
    ISSN (online) 1568-5624 ; 1568-5616
    ISSN 0920-5063
    DOI 10.1080/09205063.2018.1541500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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