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  1. Book ; Online ; E-Book: Eyelid reconstruction

    Freitag, Suzanne K. / Lee, N. Grace / Lefebvre, Daniel R. / Yoon, Michael K.

    2020  

    Author's details Suzanne K. Freitag, N. Grace Lee, Daniel R. Lefebvre, Michael K. Yoon
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (ix, 120 Seiten), Illustrationen
    Publisher Thieme
    Publishing place New York
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020355332
    ISBN 978-1-62623-824-4 ; 9781626238237 ; 1-62623-824-3 ; 1626238235
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Ophthalmic plastic surgery

    Freitag, Suzanne K. / Lee, N. Grace / Lefebvre, Daniel R. / Yoon, Michael K.

    tricks of the trade

    2020  

    Author's details Suzanne K. Freitag, N. Grace Lee, Daniel R. Lefebvre, Michael K. Yoon
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xvi, 288 Seiten), Illustrationen
    Publisher Thieme
    Publishing place New York
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020431745
    ISBN 978-1-62623-898-5 ; 9781626238978 ; 1-62623-898-7 ; 1626238979
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Orbital Penetrating Injuries: A Review on Evaluation and Management.

    Lin, Lisa Y / Lefebvre, Daniel R

    International ophthalmology clinics

    2024  Volume 64, Issue 2, Page(s) 11–29

    MeSH term(s) Humans ; Orbit/injuries ; Orbital Diseases ; Eye Injuries, Penetrating/diagnosis ; Eye Injuries, Penetrating/surgery
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0000000000000503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: "Demodicosis" Mimicking PreSeptal Cellulitis: Severe Periocular and Facial Inflammation Caused by "Normal" Skin Flora.

    Desire, Galaxy M / Stagner, Anna M / Lin, Li-Wei / Lefebvre, Daniel R

    Ophthalmic plastic and reconstructive surgery

    2024  Volume 40, Issue 3, Page(s) e72–e74

    Abstract: Due to their relatively high prevalence and commensalism, the pathogenicity of Demodex mites has been debated. Recent data, however, show Demodex to be associated with skin and ocular surface diseases such as rosacea, blepharitis, and keratitis. Here the ...

    Abstract Due to their relatively high prevalence and commensalism, the pathogenicity of Demodex mites has been debated. Recent data, however, show Demodex to be associated with skin and ocular surface diseases such as rosacea, blepharitis, and keratitis. Here the authors report the first known case, to the best of the their knowledge, of Demodex infestation mimicking preseptal cellulitis in an adult human. A 29-year-old male bilaterally blind from advanced retinopathy of prematurity presented with a 2-month history of right-greater-than-left upper eyelid and periocular/cheek swelling, redness, and ocular discharge that did not resolve with oral antibiotics or oral steroids. Based on MRI findings, biopsies of the right lacrimal gland, right orbital fat, and right upper eyelid preseptal skin were obtained which revealed marked intrafollicular Demodex mite density and budding yeasts in the upper eyelid skin. This case serves to alert clinicians to this entity that may not otherwise be usually considered in ophthalmic clinical practice.
    MeSH term(s) Humans ; Male ; Adult ; Mite Infestations/diagnosis ; Eye Infections, Parasitic/diagnosis ; Eye Infections, Parasitic/parasitology ; Diagnosis, Differential ; Cellulitis/diagnosis ; Cellulitis/microbiology ; Animals ; Mites ; Eyelid Diseases/diagnosis ; Eyelid Diseases/parasitology ; Eyelid Diseases/drug therapy ; Eyelids/parasitology ; Eyelids/pathology ; Magnetic Resonance Imaging ; Biopsy ; Orbital Cellulitis/diagnosis ; Orbital Cellulitis/microbiology
    Language English
    Publishing date 2024-05-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: A Rapidly Expanding Hemorrhagic BRAF-Mutant Orbital Atypical Glomus Tumor.

    Chang, Enchi K / Chiou, Carolina A / Lefebvre, Daniel R / Stagner, Anna M

    Ophthalmic plastic and reconstructive surgery

    2023  Volume 40, Issue 1, Page(s) e11–e14

    Abstract: A healthy 32-year-old woman presented with the acute onset of left sided eye pain, upper eyelid fullness, and binocular diplopia during light weightlifting. Examination elevated intraocular pressure, proptosis, upper eyelid ptosis, and motility deficits. ...

    Abstract A healthy 32-year-old woman presented with the acute onset of left sided eye pain, upper eyelid fullness, and binocular diplopia during light weightlifting. Examination elevated intraocular pressure, proptosis, upper eyelid ptosis, and motility deficits. CT demonstrated a well-circumscribed, homogeneous-appearing extraconal mass in the superior left orbit. The patient underwent an urgent orbitotomy with the excision of a hemorrhagic mass. Histopathology showed a glomus tumor with atypical features and hemorrhagic infarction, best classified as having uncertain malignant potential. A B-Raf proto-oncogene V600E mutation was detected with immunohistochemistry, which suggests a more aggressive tumor behavior yet presents an opportunity for targeted primary or adjunctive therapy. This is the first reported case of a B-Raf proto-oncogene-mutant atypical glomus tumor arising in the orbit.
    MeSH term(s) Female ; Humans ; Adult ; Proto-Oncogene Proteins B-raf/genetics ; Glomus Tumor/diagnosis ; Glomus Tumor/genetics ; Glomus Tumor/pathology ; Orbital Neoplasms/diagnosis ; Orbital Neoplasms/genetics ; Orbital Neoplasms/pathology ; Orbit/pathology ; Exophthalmos/diagnosis
    Chemical Substances Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; BRAF protein, human (EC 2.7.11.1)
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Periorbital necrotizing sweet syndrome: A report of two cases mimicking necrotizing soft tissue infections.

    Vongsachang, Hursuong / Chiou, Carolina A / Azad, Amee D / Lin, Lisa Y / Yoon, Michael K / Lefebvre, Daniel R / Stagner, Anna M

    American journal of ophthalmology case reports

    2024  Volume 34, Page(s) 102033

    Abstract: Purpose: Two cases are described of necrotizing Sweet syndrome (nSS), a rare variant of acute febrile neutrophilic dermatosis that mimics necrotizing soft tissue infections.: Observation: A 74-year-old female with myelodysplastic syndrome (MDS) ... ...

    Abstract Purpose: Two cases are described of necrotizing Sweet syndrome (nSS), a rare variant of acute febrile neutrophilic dermatosis that mimics necrotizing soft tissue infections.
    Observation: A 74-year-old female with myelodysplastic syndrome (MDS) presented with isolated periorbital nSS that closely mimicked necrotizing fasciitis (NF); she displayed pathergy to debridement, was exquisitely responsive to corticosteroids, and underwent successful first-stage reconstruction of the eyelid with full-thickness skin grafting. A second 40-year-old female patient with relapsed acute myelogenous leukemia (AML) presented with multifocal nSS most prominently involving the eyelid. Positive herpes zoster virus (HSV) PCR and bacterial superinfection complicated the diagnosis. She improved with chemotherapy for AML and corticosteroid therapy.
    Conclusion: nSS is rare and a high level of clinical suspicion as well as an understanding of its distinguishing features is necessary to avoid undue morbidity. Identification of pathergy, histopathology, microbiology, and clinical context are critical to avoid misdiagnosis of infection.
    Language English
    Publishing date 2024-03-02
    Publishing country United States
    Document type Case Reports
    ISSN 2451-9936
    ISSN (online) 2451-9936
    DOI 10.1016/j.ajoc.2024.102033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Perceived change in age after functional upper blepharoplasty.

    Lu, Jonathan E / Wolkow, Natalie / Lee, N Grace / Lefebvre, Daniel R / Freitag, Suzanne K / Yoon, Michael K

    Orbit (Amsterdam, Netherlands)

    2023  Volume 43, Issue 2, Page(s) 165–167

    Abstract: Purpose: To evaluate the perceived age of patients before and after functional upper blepharoplasty.: Methods: Retrospective chart review of patients who underwent upper blepharoplasty by a single surgeon at an academic center. The inclusion ... ...

    Abstract Purpose: To evaluate the perceived age of patients before and after functional upper blepharoplasty.
    Methods: Retrospective chart review of patients who underwent upper blepharoplasty by a single surgeon at an academic center. The inclusion criterion was having external photographs before and after blepharoplasty. Exclusion criteria included any other concurrent eyelid or facial surgery. Primary endpoint: perceived change in age after surgery as judged by the American Society of Ophthalmic Plastic & Reconstructive Surgery (ASOPRS) surgeons.
    Results: Sixty-seven patients (14 men, 53 women) were included. Mean pre-operative age was 66.9 years (range 37.8-89.4) and mean post-operative age was 67.4 years (range 38.6-89). The mean perceived age pre-operatively was 68.9 years, and the mean perceived age post-operatively was 67.1 years, a change of 1.8 years (
    Discussion: Functional upper blepharoplasty by an experienced ASOPRS surgeon was shown to reduce the perceived age of a patient by an average of 1.8 years.
    MeSH term(s) Male ; Humans ; Female ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Infant ; Blepharoplasty ; Retrospective Studies ; Reproducibility of Results ; Eyelids/surgery ; Face/surgery
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.1080/01676830.2023.2214940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1735: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Antibiotic utilization in endoscopic dacryocystorhinostomy: a multi-institutional study and review of the literature.

    Boal, Nina S / Chiou, Carolina A / Sadlak, Natalie / Sarmiento, V Adrian / Lefebvre, Daniel R / Distefano, Alberto G

    Orbit (Amsterdam, Netherlands)

    2023  Volume 43, Issue 2, Page(s) 183–189

    Abstract: Purpose: Utilization of antibiotics for endoscopic dacryocystorhinostomy (endo-DCR) is largely dependent on individual surgeon preference. This study aimed to investigate prescribing practices of pre-, peri-, and postoperative antibiotics and effects on ...

    Abstract Purpose: Utilization of antibiotics for endoscopic dacryocystorhinostomy (endo-DCR) is largely dependent on individual surgeon preference. This study aimed to investigate prescribing practices of pre-, peri-, and postoperative antibiotics and effects on postoperative infection rates in patients who underwent endo-DCR.
    Methods: A retrospective chart review of institutional data at two academic centers of endo-DCR cases from 2015-2020 was performed. Postoperative infection rates for patients who received pre-, peri-, and postoperative antibiotics, individually or in combination, and those who did not, were compared via odds ratio and ANOVA linear regression.
    Results: 331 endo-DCR cases were included; 22 cases (6.6%) had a postoperative infection. There was no significant difference in the infection rates between patients without an active preoperative dacryocystitis who received different permutations of peri- and postoperative antibiotics. Patients who received preoperative antibiotics within two weeks of surgery for preexisting acute dacryocystitis, but did not receive peri- or postoperative antibiotics, had a higher rate of postoperative infections (
    Conclusions: Our data suggest antibiotics may be beneficial only when patients have a recent or active dacryocystitis prior to surgery. Otherwise, our data do not support the routine use of antibiotic prophylaxis in endo-DCR.
    MeSH term(s) Humans ; Dacryocystorhinostomy ; Anti-Bacterial Agents/therapeutic use ; Nasolacrimal Duct/surgery ; Retrospective Studies ; Endoscopy ; Dacryocystitis/drug therapy ; Dacryocystitis/surgery ; Postoperative Complications/surgery ; Treatment Outcome ; Multicenter Studies as Topic
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.1080/01676830.2023.2227705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Orbital Involvement by Biphenotypic Sinonasal Sarcoma With a Literature Review.

    Hanbazazh, Mehenaz / Jakobiec, Frederick A / Curtin, Hugh D / Lefebvre, Daniel R

    Ophthalmic plastic and reconstructive surgery

    2020  Volume 37, Issue 4, Page(s) 305–311

    Abstract: Purpose: To document a case of a biphenotypic sinonasal sarcoma that impinged on the orbit via a tumor-induced mucocele and review the previous literature devoted to this condition.: Methods: A clinicopathologic case report with detailed ... ...

    Abstract Purpose: To document a case of a biphenotypic sinonasal sarcoma that impinged on the orbit via a tumor-induced mucocele and review the previous literature devoted to this condition.
    Methods: A clinicopathologic case report with detailed histopathologic, immunohistochemical, and radiological studies with tabulations of previously reported cases and immunohistochemical stains for ruling out mimicking lesions.
    Results: A biphenotypic sinonasal sarcoma arose from the ethmoid sinus in a middle-aged man. The tumor induced a mucocele that bowed the medial orbital lamina papyracea into the orbit and caused diplopia and mild proptosis. The biopsy's dual positivity for S100 and smooth muscle actin together with positive paired box 3 immunohistochemical staining established the diagnosis of biphenotypic sinonasal sarcoma.
    Conclusion: Biphenotypic sinonasal sarcoma, which can involve the orbit in 25% of cases, is a rare head and neck malignancy that has only recently been described. Biphenotypic sinonasal sarcoma is a low-grade, locally aggressive, nonmetastasizing sarcoma displaying both neural and muscle differentiation. It is further characterized by rearrangements of the PAX3 gene with multiple fusion partners, most commonly MAML3 (Mastermind like transcriptional coactivator 3). It occurs predominantly in middle-aged women and exclusively in the sinonasal tract. However, it can spread throughout the central facial structures to invade the brain if not detected early. Ophthalmologists should be aware of this new entity to avoid delays in diagnosis and treatment. The previous literature devoted to this condition was reviewed and analyzed for clinical, radiological, histopathological, and immunohistochemical features. In circumstances where molecular testing is not available, paired box 3 immunohistochemical staining can be used as an alternative diagnostic marker. The current case is most unusual because the orbital findings were induced by a mucocele caused by the tumor that obstructed the sinus ostium. This produced diplopia without direct tumor invasion into the orbital fat.
    MeSH term(s) Biomarkers, Tumor ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; PAX3 Transcription Factor ; Paranasal Sinus Neoplasms/diagnosis ; Sarcoma
    Chemical Substances Biomarkers, Tumor ; PAX3 Transcription Factor
    Language English
    Publishing date 2020-10-06
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000001839
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2159: Show issues Location:
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  10. Article ; Online: Adult-onset asthma and periocular xanthogranuloma - A rare infiltrative disease of the orbit and eyelid.

    Green, Michael B / Daly, Mary K / Laver, Nora M V / Lefebvre, Daniel R

    American journal of ophthalmology case reports

    2021  Volume 22, Page(s) 101043

    Abstract: Purpose: To present a case of adult onset asthma with periocular xanthogranuloma (AAPOX), and discuss existing literature on adult orbital xanthogranulomatous diseases (AOXGDs) and their treatment.: Observations: A 63 year old male presented with ... ...

    Abstract Purpose: To present a case of adult onset asthma with periocular xanthogranuloma (AAPOX), and discuss existing literature on adult orbital xanthogranulomatous diseases (AOXGDs) and their treatment.
    Observations: A 63 year old male presented with progressive bilateral eyelid swelling with overlying yellow plaques associated with asthma. CT scan showed periorbital swelling with enlargement of the superior and lateral rectus muscles bilaterally. Biopsy demonstrated orbital xanthogranulomatous disease with increased IgG4 plasma cells. The patient was treated with intralesional triamcinolone, oral prednisone, and cyclophosphamide without significant improvement. Surgical debulking was eventually performed which improved his external symptoms until he was lost to follow up 15 months later.
    Conclusions and importance: AOXGDs are a group of rare infiltrative diseases of the eyelids and orbit that can be associated with significant systemic morbidities. While they all have similar underlying histopathologic features, appreciating the clinical difference between these diseases is important in understanding patient prognosis and ensuring appropriate clinical monitoring. There is also growing research demonstrating that AAPOX, along with other AOXGDs, may represent part of a continuum of IgG4 related disease, similar to what is seen in this case. There is currently no reliably effective treatment for AOXGDs, and additional research into the management of these diseases is necessary.
    Language English
    Publishing date 2021-03-21
    Publishing country United States
    Document type Case Reports
    ISSN 2451-9936
    ISSN (online) 2451-9936
    DOI 10.1016/j.ajoc.2021.101043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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