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  1. Article ; Online: Correction.

    Legault, Geoffrey / Kingsolver, Joel G

    The American naturalist

    2021  Volume 198, Issue 3, Page(s) 437

    Language English
    Publishing date 2021-06-14
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 207092-3
    ISSN 1537-5323 ; 0003-0147
    ISSN (online) 1537-5323
    ISSN 0003-0147
    DOI 10.1086/715152
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  2. Article: Predicting age and mass at maturity from feeding behavior and diet in

    Parker, Anna L / Albright, Anna / Kingsolver, Joel G / Legault, Geoffrey

    Ecology and evolution

    2023  Volume 13, Issue 2, Page(s) e9848

    Abstract: Feeding for most animals involves bouts of active ingestion alternating with bouts of no ingestion. In insects, the temporal patterning of bouts varies widely with resource quality and is known to affect growth, development time, and fitness. However, ... ...

    Abstract Feeding for most animals involves bouts of active ingestion alternating with bouts of no ingestion. In insects, the temporal patterning of bouts varies widely with resource quality and is known to affect growth, development time, and fitness. However, the precise impacts of resource quality and feeding behavior on insect life history traits are poorly understood. To explore and better understand the connections between feeding behavior, resource quality, and insect life history traits, we combined laboratory experiments with a recently proposed mechanistic model of insect growth and development for a larval herbivore,
    Language English
    Publishing date 2023-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.9848
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  3. Article ; Online: Métis health in Canada: a scoping review of Métis-specific health literature.

    Gmitroski, Krysta-Leigh / Hastings, Katherine G / Legault, Gabrielle / Barbic, Skye

    CMAJ open

    2023  Volume 11, Issue 5, Page(s) E884–E893

    Abstract: Background: Métis are a culturally unique and distinct population, yet little research has evaluated their health separate from the broader Indigenous population. We sought to explore current literature regarding the health of Métis Peoples in Canada ... ...

    Abstract Background: Métis are a culturally unique and distinct population, yet little research has evaluated their health separate from the broader Indigenous population. We sought to explore current literature regarding the health of Métis Peoples in Canada and identify potential trends and gaps.
    Methods: Using the Arksey-O'Malley, 5-stage, scoping review method, we searched PubMed, MEDLINE, iPortal Indigenous Articles Portal Research Tool and pertinent reference lists using the terms "Métis," "health" and "Canada." Two reviewers conducted the initial searches independently, including English articles from 2012 to 2022, and focused on only Métis populations' health within Canada. We described characteristics of the articles and themes for discussion.
    Results: Of the 572 articles we identified, we included a total of 28 articles in this scoping review, of which 16 were quantitative, 9 were qualitative and 3 used mixed methods. Thirteen articles used consultation with Métis communities as part of their methods, and 8 extracted data from national surveys. One article focused on children, while all other articles focused on adults. Nine articles used data from across Canada, 6 were based in Ontario, 5 in Alberta and 4 each in British Columbia and Manitoba. Themes included health, well-being and spirituality; mental health and substance use; health conditions and risk factors; access to adequate health resources; and experiences in health care.
    Interpretation: Métis-specific health research is lacking in Canada, with a gap in volume, subject matter and diversity in the demographics studied. This review illustrates the need for more research with strong community engagement to further explore Métis health and health service needs.
    Language English
    Publishing date 2023-10-03
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2701622-5
    ISSN 2291-0026 ; 2291-0026
    ISSN (online) 2291-0026
    ISSN 2291-0026
    DOI 10.9778/cmajo.20230006
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  4. Article ; Online: Data Sciences and Visual Health Disparities.

    Legault, Gary / Nwanyanwu, Kristen / Baxter, Sally L

    Ophthalmology

    2022  Volume 129, Issue 10, Page(s) 1085–1086

    MeSH term(s) Data Science ; Health Status Disparities ; Healthcare Disparities ; Humans
    Language English
    Publishing date 2022-09-01
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2022.06.032
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  5. Article ; Online: A Stochastic Model for Predicting Age and Mass at Maturity of Insects.

    Legault, Geoffrey / Kingsolver, Joel G

    The American naturalist

    2020  Volume 196, Issue 2, Page(s) 227–240

    Abstract: Variation in age and mass at maturity is commonly observed in populations, even among individuals with the same genetic and environmental backgrounds. Accounting for such individual variation with a stochastic model is important for estimating optimal ... ...

    Abstract Variation in age and mass at maturity is commonly observed in populations, even among individuals with the same genetic and environmental backgrounds. Accounting for such individual variation with a stochastic model is important for estimating optimal evolutionary strategies and for understanding potential trade-offs among life-history traits. However, most studies employ stochastic models that are either phenomenological or account for variation in only one life-history trait. We propose a model based on the developmental biology of the moth
    MeSH term(s) Aging ; Animal Nutritional Physiological Phenomena ; Animals ; Body Weight ; Larva/growth & development ; Larva/physiology ; Life History Traits ; Manduca/growth & development ; Manduca/physiology ; Models, Statistical ; Stochastic Processes
    Language English
    Publishing date 2020-06-15
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 207092-3
    ISSN 1537-5323 ; 0003-0147
    ISSN (online) 1537-5323
    ISSN 0003-0147
    DOI 10.1086/709503
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  6. Article ; Online: Brief report: Refractive surgery trends at tri-service refractive surgery centers and the impact of the COVID-19 pandemic, fiscal years 2000-2020.

    Sellers, Brandon / Townley, J Richard / Ropp, Corby / Legault, Gary

    MSMR

    2022  Volume 29, Issue 3, Page(s) 17–19

    MeSH term(s) COVID-19/epidemiology ; Humans ; Military Personnel ; Ophthalmology ; Pandemics ; Refractive Surgical Procedures
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2623409-9
    ISSN 2152-8217 ; 2152-8217
    ISSN (online) 2152-8217
    ISSN 2152-8217
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  7. Article ; Online: Data Sources for Evaluating Health Disparities in Ophthalmology: Where We Are and Where We Need to Go.

    Baxter, Sally L / Nwanyanwu, Kristen / Legault, Gary / Lee, Aaron Y

    Ophthalmology

    2022  Volume 129, Issue 10, Page(s) e146–e149

    Abstract: Data provide an opportunity to discover disparities and inequities that may otherwise be unrecognized. Within the American Academy of Ophthalmology (AAO) Task Force on Disparities in Eye Care, the Leveraging Data Sub-task Force was charged with ... ...

    Abstract Data provide an opportunity to discover disparities and inequities that may otherwise be unrecognized. Within the American Academy of Ophthalmology (AAO) Task Force on Disparities in Eye Care, the Leveraging Data Sub-task Force was charged with identifying data sources to study health disparities in eye care and to leverage data to advance health equity. We evaluated large data sources to determine their strengths, deficiencies, and relative accessibility in relation to the likelihood of identifying eye care disparities. We highlight the current challenges with these data sources and review key recommendations for improving future sources for studying health disparities in eye care.
    MeSH term(s) Academies and Institutes ; Healthcare Disparities ; Humans ; Information Storage and Retrieval ; Ophthalmology ; United States
    Language English
    Publishing date 2022-09-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2022.06.035
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  8. Article ; Online: Advances in pediatric gliomas: from molecular characterization to personalized treatments.

    Sathyakumar, Sayanthen / Martinez, Matthew / Perreault, Sébastien / Legault, Geneviève / Bouffet, Eric / Jabado, Nada / Larouche, Valérie / Renzi, Samuele

    European journal of pediatrics

    2024  

    Abstract: Pediatric gliomas, consisting of both pediatric low-grade (pLGG) and high-grade gliomas (pHGG), are the most frequently occurring brain tumors in children. Over the last decade, several milestone advancements in treatments have been achieved as a result ... ...

    Abstract Pediatric gliomas, consisting of both pediatric low-grade (pLGG) and high-grade gliomas (pHGG), are the most frequently occurring brain tumors in children. Over the last decade, several milestone advancements in treatments have been achieved as a result of stronger understanding of the molecular biology behind these tumors. This review provides an overview of pLGG and pHGG highlighting their clinical presentation, molecular characteristics, and latest advancements in therapeutic treatments.  Conclusion: The increasing understanding of the molecular biology characterizing pediatric low and high grade gliomas has revolutionized treatment options for these patients, especially in pLGG. The implementation of next generation sequencing techniques for these tumors is crucial in obtaining less toxic and more efficacious treatments. What is Known: • Pediatric Gliomas are the most common brain tumour in children. They are responsible for significant morbidity and mortality in this population. What is New: • Over the last two decades, there has been a significant increase in our global understanding of the molecular background of pediatric low and high grade gliomas. • The implementation of next generation sequencing techniques for these tumors is crucial in obtaining less toxic and more efficacious treatments, with the ultimate goal of improving both the survival and the quality of life of these patients.
    Language English
    Publishing date 2024-04-01
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-024-05540-4
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  9. Article ; Online: Retrospective review of Duke men's basketball eye care: annual screenings and traumatic injuries.

    Wisely, C Ellis / Legault, Gary / Kim, Terry

    The Physician and sportsmedicine

    2020  Volume 49, Issue 3, Page(s) 337–341

    Abstract: Objectives: 1) To assess the utility of performing eye screenings for healthy basketball players. 2) To describe the traumatic injuries sustained by competitive college basketball players.: Methods: The eye screening examinations of the Duke ... ...

    Abstract Objectives: 1) To assess the utility of performing eye screenings for healthy basketball players. 2) To describe the traumatic injuries sustained by competitive college basketball players.
    Methods: The eye screening examinations of the Duke University Men's Basketball players over six seasons were reviewed retrospectively. Traumatic basketball-related eye injuries amongst Duke University Men's Basketball players over 16 seasons were also reviewed and described.
    Results: Forty-four total players underwent screening examinations. Thirteen (29.5%) of athletes had uncorrected or under-corrected refractive errors. One athlete was found to have a severe monocular visual deficit secondary to a traumatic injury in childhood, which was significantly mitigated by a contact lens referral. Eight traumatic ocular injuries in eight different athletes, 8.6% of the total roster players in this interval, required ophthalmologic consultation. Most injuries, 7/8, resulted in no permanent visual impairment. However, two severe episodes of injury required operative intervention, and one episode involving a giant retinal dialysis and traumatic optic nerve head avulsion caused severe, permanent visual loss. Most injuries did not result in significant competition time loss, with a median time loss of 5 days (range 0 to 240 days).
    Conclusion: Screening eye examinations in healthy athletes are beneficial for the identification and treatment of refractive errors. Traumatic basketball-related eye injuries are common and result in a wide array of injuries. Although most basketball-related eye injuries do no result in permanent visual loss, given the potential for severe injury, many basketball-related eye injuries require expert ophthalmic consultation.
    MeSH term(s) Athletes ; Athletic Injuries/diagnosis ; Athletic Injuries/therapy ; Basketball/injuries ; Diagnostic Techniques, Ophthalmological ; Eye Injuries/diagnosis ; Eye Injuries/therapy ; Humans ; Incidence ; Male ; North Carolina ; Retrospective Studies ; Universities
    Language English
    Publishing date 2020-10-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 753046-8
    ISSN 2326-3660 ; 0091-3847
    ISSN (online) 2326-3660
    ISSN 0091-3847
    DOI 10.1080/00913847.2020.1835137
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  10. Article ; Online: Initial abundance and stochasticity influence competitive outcome in communities.

    Dallas, Tad / Melbourne, Brett A / Legault, Geoffrey / Hastings, Alan

    The Journal of animal ecology

    2021  Volume 90, Issue 7, Page(s) 1691–1700

    Abstract: Predicting competitive outcomes in communities frequently involves inferences based on deterministic population models since these provide clear criteria for exclusion (e.g. R* rule) or long-term coexistence (e.g. mutual invasibility). However, ... ...

    Abstract Predicting competitive outcomes in communities frequently involves inferences based on deterministic population models since these provide clear criteria for exclusion (e.g. R* rule) or long-term coexistence (e.g. mutual invasibility). However, incorporating stochasticity into population- or community-level processes into models is necessary if the goal is to explain variation in natural systems, which are inherently stochastic. Similarly, in systems with demographic or environmental stochasticity, weaker competitors have the potential to exclude superior competitors, contributing to what is known as 'competitive indeterminacy'. The importance of such effects for natural communities is unknown, in part because it is difficult to demonstrate that multiple forms of stochasticity are present in these communities. Moreover, the effects of multiple forms of stochasticity on competitive outcomes are largely untested, even in theory. Here, we address these issues by examining the role of stochasticity in replicated communities of flour beetles (Tribolium sp.). To do so, we developed a set of two-species stochastic Ricker models incorporating four distinct forms of stochasticity: environmental stochasticity, demographic stochasticity, demographic heterogeneity and stochastic sex determination. By fitting models to experimental data, and simulating fit models to examine long- term behaviour, we found that both the duration of transient coexistence and the degree of competitive indeterminacy were sensitive to the forms of stochasticity included in our models. These findings suggest the current estimates of extinction risk, coexistence and time until competitive exclusion in communities may not be accurate when based on models that exclude relevant forms of stochasticity.
    MeSH term(s) Animals ; Coleoptera ; Ecosystem ; Models, Biological ; Population Dynamics ; Stochastic Processes ; Tribolium
    Language English
    Publishing date 2021-04-30
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 3024-7
    ISSN 1365-2656 ; 0021-8790
    ISSN (online) 1365-2656
    ISSN 0021-8790
    DOI 10.1111/1365-2656.13485
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