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  1. Article ; Online: Implementation of Robotic Exoscope in Minimally Invasive Corpectomy at Thoracolumbar Junction for the Treatment of Traumatic Spinal Cord Compression.

    Giorgi, Pietro Domenico / Legrenzi, Simona / Sacchi, Lorenzo / Boeris, Davide / Villa, Fabio Giuseppe / Bove, Federico / Puglia, Francesco / Schirò, Giuseppe Rosario

    World neurosurgery

    2024  Volume 184, Page(s) 23–28

    Abstract: The development and diffusion of minimally invasive (MI) approaches have coincided with improvements in magnification systems. The exoscope will probably open a new era in new technologies in spinal surgery. This study reports a retrospective series of ... ...

    Abstract The development and diffusion of minimally invasive (MI) approaches have coincided with improvements in magnification systems. The exoscope will probably open a new era in new technologies in spinal surgery. This study reports a retrospective series of 19 thoracolumbar (T11-L2) burst fractures with anterior column failure and cord compression, treated with MI corpectomy and spinal decompression assisted by a three-dimensional high-definition exoscope (Video 1). Exclusion criteria were pathologic or osteoporotic fractures, multilevel fractures, and previous surgery at the site of the fracture. Three key indicators were recorded: surgical time, blood loss, and intraoperative complications. A questionnaire was administered to assess the users' exoscope experience with ergonomics, preparation, magnification, image definition, illumination, and user-friendliness, compared with the operative microscope. To the best of our knowledge, this is the first study reporting on exoscope-assisted MI corpectomy. This procedure permitted low blood loss and less surgical time without intraoperative complications. The exoscope offers clear advantages in terms of ergonomics, definition, and user-friendliness. Moreover, it is a suitable instrument for training and education, providing an opportunity for better interaction with other members of the surgical staff.
    MeSH term(s) Humans ; Spinal Cord Compression/etiology ; Spinal Cord Compression/surgery ; Retrospective Studies ; Robotic Surgical Procedures ; Neurosurgical Procedures/methods ; Spinal Fractures/surgery ; Intraoperative Complications/surgery ; Lumbar Vertebrae/surgery ; Lumbar Vertebrae/injuries ; Minimally Invasive Surgical Procedures/methods ; Thoracic Vertebrae/surgery ; Thoracic Vertebrae/injuries
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Video-Audio Media
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.12.163
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
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  2. Article ; Online: Spinal cord compression in dialysis-related upper cervical amyloidoma - a case report.

    Giorgi, Pietro Domenico / Pallotta, Maria Ludovica / Legrenzi, Simona / Schirò, Giuseppe Rosario

    Spinal cord series and cases

    2021  Volume 7, Issue 1, Page(s) 40

    Abstract: Introduction: Dialysis-related amyloidosis (DRA) can lead to various degenerative conditions but rarely involves the spine with a spinal cord compression.: Case report: The authors describe a progressive tetraparesis (AIS-B) in a 57-year-old woman ... ...

    Abstract Introduction: Dialysis-related amyloidosis (DRA) can lead to various degenerative conditions but rarely involves the spine with a spinal cord compression.
    Case report: The authors describe a progressive tetraparesis (AIS-B) in a 57-year-old woman with upper cervical dialysis-related amyloidoma. Magnetic resonance imaging (MRI) showed a solid focal mass lesion at the C2-odotoid level with severe spinal cord compression. Computed tomography (CT) outlined multiple lytic lesions in C1 lateral masses and odontoid process. The patient underwent urgent surgical treatment. A posterior C1-C2 spinal cord decompression with biopsy followed by occipito-cervical posterior fixation was performed. Histopathological examination revealed amyloid deposits representing DRA. An immediately postoperative neurological improvement was observed.
    Discussion: Even if the spinal amyloidoma is extremely rare, this condition has to be suspected in a long-term hemodialysis patient suffering from progressive neurological deficits. Differential diagnosis is mandatory between infections, rheumatologic and neoplastic lesions. Imaging evaluation with CT and MRI is recommended in order to assess the characteristics of the pathological mass, the extension of lytic lesions and the entity of neurological compression. Surgical treatment is mandatory if clinical evidence of root or spinal cord compression is present.
    MeSH term(s) Amyloidosis/diagnosis ; Amyloidosis/etiology ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Female ; Humans ; Middle Aged ; Odontoid Process ; Renal Dialysis/adverse effects ; Spinal Cord Compression/diagnosis ; Spinal Cord Compression/etiology ; Spinal Cord Compression/surgery
    Language English
    Publishing date 2021-05-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 2058-6124
    ISSN (online) 2058-6124
    DOI 10.1038/s41394-021-00409-2
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  3. Article ; Online: Spinal cord compression in thoracolumbar burst fractures: application of high-definition three-dimensional exoscope in minimally invasive lateral surgery.

    Giorgi, Pietro Domenico / Pallotta, Maria Ludovica / Legrenzi, Simona / Nardi, Michele / Andrea, Manzoni / Schirò, Giuseppe Rosario

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2022  Volume 33, Issue 5, Page(s) 2173–2177

    Abstract: Study design: Spinal cord decompression in thoracolumbar burst fractures is challenging. Development of minimally invasive approaches and the improvement in new magnification technologies allowed a better and safer surgical treatment for these complex ... ...

    Abstract Study design: Spinal cord decompression in thoracolumbar burst fractures is challenging. Development of minimally invasive approaches and the improvement in new magnification technologies allowed a better and safer surgical treatment for these complex spinal injuries. We reported our experience in the minimally invasive surgical treatment of thoracolumbar burst fractures with spinal cord compression supported by high-definition (HD) three-dimensional (3D) Video-assisted telescope operating monitor (VITOM) or exoscope.
    Objectives: To assess the role and potential advantages of exoscope in the minimally invasive surgery of traumatic thoracolumbar spinal cord compression comparing traditional magnification systems.
    Setting: The study was conducted in a Northern Italy Spinal Trauma Center.
    Methods: We reported 10 consecutive thoracolumbar (T11-L2) burst fractures associated with spinal cord compression treated with minimally invasive corpectomy and exoscope-assisted spinal decompression. Three main indicators were retrospectively analyzed: surgical time, blood loss, and intraoperative complications. The data were compared with those obtained from an equal sample of 10 procedures performed by the same surgeon with the same technique, but traditional microscope assisted. User impressions in terms of ergonomics, magnification, and image quality were rated differently.
    Results: A small reduction of surgical time and blood loss were observed in the exoscope assisted group. There were no intraoperative complications attributed to visualization mode or conversion to the traditional microscope in any procedure. In our experience the exoscope allowed a better magnification and image definition with better ergonomics and user-friendliness.
    Conclusions: In our preliminary experience the exoscope new technology is a safe and effective tool for spinal cord minimally invasive decompression in thoracolumbar burst fractures. The stereoscopic vision provided by 3D images seems to be crucial in hand eye coordination. There are clear advantages in terms of maneuverability, wide field of view, deep focus, and more comfortable posture for the spinal surgeon.
    MeSH term(s) Humans ; Spinal Cord Compression/etiology ; Spinal Cord Compression/surgery ; Retrospective Studies ; Laminectomy ; Decompression, Surgical/methods ; Minimally Invasive Surgical Procedures ; Spinal Fractures/surgery
    Language English
    Publishing date 2022-07-26
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-022-03319-7
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    Zs.A 3479: Show issues Location:
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  4. Article: Integrated spine trauma team protocol: Combined neurosurgical and orthopedic experience for the management of traumatic spinal injuries.

    Giorgi, Pietro Domenico / Villa, Fabio Giuseppe / Cenzato, Marco / Capitani, Dario / Antonio, D'Aliberti Giuseppe / Legrenzi, Simona / Puglia, Francesco / Picano, Marco / Boeris, Davide / Debernardi, Alberto / Schirò, Giuseppe Rosario

    Journal of neurosciences in rural practice

    2023  Volume 14, Issue 3, Page(s) 459–464

    Abstract: Objectives: During the last decades, spine surgery has grown exponentially. In spite of that, it remains a surgical specialty without a well-defined own certification. It is usually carried out, separately, by neurosurgeons and orthopedic surgeons, even ...

    Abstract Objectives: During the last decades, spine surgery has grown exponentially. In spite of that, it remains a surgical specialty without a well-defined own certification. It is usually carried out, separately, by neurosurgeons and orthopedic surgeons, even if there is an overlapping of competence and skills.
    Materials and methods: In our hospital, from January 2019, a systematic protocol called integrated spine trauma team protocol (ISTTP) was implemented to improve the management of traumatic spinal injuries in a multidisciplinary way. It is characterized by a specific algorithm from diagnosis to postoperative care. According to the new protocol, orthopedic spinal surgeons and neurosurgeons work together as an integrated spine trauma team. The authors analyzed, retrospectively, the results obtained by comparing patients treated before and after the application of the ISTTP.
    Results: The new protocol allowed a statistically significant reduction in waiting time before surgery and complication rate. Moreover, early discharge of patients was recorded. To the best of our knowledge, this is the first study that described a specific algorithm for a standardized multidisciplinary management of the spinal trauma with combined orthopedic and neurosurgeon expertise.
    Conclusion: Our preliminary results suggest that the application of our ISTTP leads to better results for treating traumatic spinal injury (TSI).
    Language English
    Publishing date 2023-06-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2601242-X
    ISSN 0976-3155 ; 0976-3147
    ISSN (online) 0976-3155
    ISSN 0976-3147
    DOI 10.25259/JNRP_52_2022
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  5. Article ; Online: Spinal injury in major trauma: Epidemiology of 1104 cases from an Italian first level trauma center.

    Spota, Andrea / Giorgi, Pietro Domenico / Cioffi, Stefano Piero Bernardo / Altomare, Michele / Schirò, Giuseppe Rosario / Legrenzi, Simona / Villa, Fabio Giuseppe / Chiara, Osvaldo / Cimbanassi, Stefania

    Injury

    2023  Volume 54, Issue 4, Page(s) 1144–1150

    Abstract: Introduction: Traumatic spinal injuries are frequent and their management is debated, especially in major trauma patients. This study aims to describe a large population of major trauma patients with vertebral fractures to improve prevention measures ... ...

    Abstract Introduction: Traumatic spinal injuries are frequent and their management is debated, especially in major trauma patients. This study aims to describe a large population of major trauma patients with vertebral fractures to improve prevention measures and fracture management.
    Patients and methods: Retrospective analysis of 6274 trauma patients prospectively collected between October 2010 and October 2020. Collected data include demographics, mechanism of trauma, type of imaging, fracture morphology, associated injuries, injury severity score (ISS), survival, and death timing. The statistical analysis focused on mechanism of trauma and the search of predictive factors for critical fractures.
    Results: Patients showed a mean age of 47 years and 72.5% were males. Trauma included 59.9% of road accidents and 35.1% of falls. 30.7% patients had at least a severe fracture, while 17.2% had fractures in multiple spinal regions. 13.7% fractures were complicated by spinal cord injury (SCI). The mean ISS of the total population was 26.4 (SD 16.3), with 70.7% patients having an ISS≥16. There is a higher rate of severe fractures in fall cases (40.1%) compared to RA (21.9% to 26.3%). The probability of a severe fracture increased by 164% in the case of fall and by 77% in presence of AIS≥3 associated injury of head/neck while reduced by 34% in presence of extremities associated injuries. Multiple level injuries increased with ISS rise and in the case of extremities associated injuries. The probability of a severe upper cervical fracture increased by 5.95 times in the presence of facial associated injuries. The mean length of stay was 24.7 days and 9.6% of patients died.
    Conclusions: In Italy, road accidents are still the most frequent trauma mechanism and cause more cervico-thoracic fractures, while falls cause more lumbar fractures. Spinal cord injuries represent an indicator of more severe trauma. In motorcyclists or fallers/jumpers, there is a higher risk of severe fractures. When a spinal injury is diagnosed, the probability of a second vertebral fracture is consistent. These data could help the decisional workflow in the management of major trauma patients with vertebral injury.
    MeSH term(s) Male ; Humans ; Middle Aged ; Female ; Trauma Centers ; Retrospective Studies ; Spinal Injuries/complications ; Fractures, Bone/complications ; Spinal Fractures/epidemiology ; Spinal Fractures/complications ; Spinal Cord Injuries/epidemiology ; Spinal Cord Injuries/complications ; Injury Severity Score ; Multiple Trauma/complications ; Facial Injuries
    Language English
    Publishing date 2023-02-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2023.02.039
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    Zs.A 778: Show issues Location:
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    Zs.MO 10: Show issues

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  6. Article ; Online: Severe adolescent idiopathic scoliosis: posterior staged correction using a temporary magnetically-controlled growing rod.

    Di Silvestre, Mario / Zanirato, Andrea / Greggi, Tiziana / Scarale, Antonio / Formica, Matteo / Vallerga, Davide / Legrenzi, Simona / Felli, Lamberto

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

    2020  Volume 29, Issue 8, Page(s) 2046–2053

    Abstract: Purpose: A two-staged posterior correction, using a temporary magnetically controlled growing rod (MCGR), was employed to gradually and safely correct severe adolescent idiopathic scoliosis (AIS). The aim of the study is illustrating the results of this ...

    Abstract Purpose: A two-staged posterior correction, using a temporary magnetically controlled growing rod (MCGR), was employed to gradually and safely correct severe adolescent idiopathic scoliosis (AIS). The aim of the study is illustrating the results of this procedure.
    Methods: A retrospective review of a consecutive series of 17 severe AIS. The first surgery was a posterior release (multiple Ponte osteotomies) with implant of pedicle screws and MCGR on the concave side of the curve. In post-operative days, a distraction was applied with MCGR, which allowed to obtain a total mean lengthening of 2 cm in about 2 weeks, with no complications arising. In the second posterior surgery, MCGR was removed and the definitive rods were applied for final fusion. The mean pedicle screws density was 93.3% (85-100). The extension of the final posterior fusion-instrumentation was of 13.8 levels (12-15).
    Results: At an average follow-up (FU) of 2.9 years, the main scoliosis curves from average pre-operative Cobb angle of 98.2° (91°-138°) bent down to 38.3° (35°-76°) after definitive fusion (p < 0.05); at last FU, the overall correction was 58.7% (50.4-71.2), with an average correction loss of 2.1° (1.5°-3.1°). At last FU, no complications were reported.
    Conclusions: Gradual traction with MCGR in severe AIS proved to be a safe method to achieve progressive curve correction before posterior final fusion, with no neurologic complications associated to more aggressive one-stage surgeries. In a staged approach, MCGR appears as an alternative to halo traction, avoiding frequent traction-related complications.
    MeSH term(s) Adolescent ; Humans ; Kyphosis ; Pedicle Screws ; Retrospective Studies ; Scoliosis/diagnostic imaging ; Scoliosis/surgery ; Spinal Fusion ; Treatment Outcome
    Language English
    Publishing date 2020-06-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1115375-1
    ISSN 1432-0932 ; 0940-6719
    ISSN (online) 1432-0932
    ISSN 0940-6719
    DOI 10.1007/s00586-020-06483-8
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    Zs.A 3437: Show issues Location:
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  7. Article ; Online: Relationship between lumbar lordosis, pelvic parameters, PI-LL mismatch and outcome after short fusion surgery for lumbar degenerative disease. Literature review, rational and presentation of public study protocol: RELApSE study (registry for evaluation of lumbar artrodesis sagittal alignEment).

    Tartara, Fulvio / Garbossa, Diego / Armocida, Daniele / Di Perna, Giuseppe / Ajello, Marco / Marengo, Nicola / Bozzaro, Marco / Petrone, Salvatore / Giorgi, Pietro Domenico / Schirò, Giuseppe Rosario / Legrenzi, Simona / Boeris, Davide / Piazzolla, Andrea / Passarelli, Anna Claudia / Longo, Alessandro / Ducati, Alessandro / Penner, Federica / Tancioni, Flavio / Bona, Alberto /
    Paternò, Giovanni / Tassorelli, Cristina / De Icco, Roberto / Lamaida, Giovanni Andrea / Gallazzi, Enrico / Pilloni, Giulia / Colombo, Elena Virginia / Gaetani, Paolo / Aimar, Enrico / Zoia, Cesare / Stefini, Roberto / Rusconi, Angelo / Querenghi, Amos M / Brembilla, Carlo / Bernucci, Claudio / Fanti, Andrea / Frati, Alessandro / Manelli, Antonio / Muzii, Vitaliano / Sedia, Mattia / Romano, Alberto / Baram, Ali / Figini, Silvia / Ballante, Elena / Gioia, Giuseppe / Locatelli, Marco / Pluderi, Mauro / Morselli, Carlotta / Bassani, Roberto / Costa, Francesco / Cofano, Fabio

    World neurosurgery: X

    2023  Volume 18, Page(s) 100162

    Abstract: Background: Vertebral arthrodesis for degenerative pathology of the lumbar spine still remains burdened by clinical problems with significant negative results. The introduction of the sagittal balance assessment with the evaluation of the meaning of ... ...

    Abstract Background: Vertebral arthrodesis for degenerative pathology of the lumbar spine still remains burdened by clinical problems with significant negative results. The introduction of the sagittal balance assessment with the evaluation of the meaning of pelvic parameters and spinopelvic (PI-LL) mismatch offered new evaluation criteria for this widespread pathology, but there is a lack of consistent evidence on long-term outcome.
    Methods: The authors performed an extensive systematic review of literature, with the aim to identify all potentially relevant studies about the role and usefulness of the restoration or the assessment of Sagittal balance in lumbar degenerative disease. They present the study protocol RELApSE (NCT05448092 ID) and discuss the rationale through a comprehensive literature review.
    Results: From the 237 papers on this topic, a total of 176 articles were selected in this review. The analysis of these literature data shows sparse and variable evidence. There are no observations or guidelines about the value of lordosis restoration or PI-LL mismatch. Most of the works in the literature are retrospective, monocentric, based on small populations, and often address the topic evaluation partially.
    Conclusions: The RELApSE study is based on the possibility of comparing a heterogeneous population by pathology and different surgical technical options on some homogeneous clinical and anatomic-radiological measures aiming to understanding the value that global lumbar and segmental lordosis, distribution of lordosis, pelvic tilt, and PI-LL mismatch may have on clinical outcome in lumbar degenerative pathology and on the occurrence of adjacent segment disease.
    Language English
    Publishing date 2023-01-27
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2590-1397
    ISSN (online) 2590-1397
    DOI 10.1016/j.wnsx.2023.100162
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