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  1. Book ; Thesis: Untersuchungen zur Bedeutung einer Mutation im Calreticulin-Gen für die Differentialdiagnose und Prognose von Patienten mit einer Myeloproliferativen Neoplasie (MPN)

    Stadler, Julia-Christina / Lehmann, Ulrich

    2017  

    Institution Medizinische Hochschule Hannover
    Medizinische Hochschule Hannover / Institut für Pathologie
    Author's details vorgelegt von Julia-Christina Stadler aus Minden ; aus dem Institut für Pathologie der Medizinischen Hochschule Hannover ; Wissenschaftliche Betreuung: Prof. Dr. rer. nat. Ulrich Lehmann-Mühlenhoff
    Language German
    Size 3 ungezählte Blätter, 125 Blätter, Illustrationen, Diagramme
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2018
    HBZ-ID HT020078953
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 E 466 order for loan Magazin

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  2. Article ; Online: Der Biomarker PIK3CA in der Tumorpathologie.

    Lehmann, Ulrich / Stenzinger, Albrecht

    Pathologie (Heidelberg, Germany)

    2023  Volume 44, Issue 4, Page(s) 259–260

    Title translation The biomarker PIK3CA in tumor pathology.
    MeSH term(s) Humans ; Neoplasms/diagnosis ; Class I Phosphatidylinositol 3-Kinases/genetics
    Chemical Substances Class I Phosphatidylinositol 3-Kinases (EC 2.7.1.137) ; PIK3CA protein, human (EC 2.7.1.137)
    Language German
    Publishing date 2023-03-17
    Publishing country Germany
    Document type Journal Article
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-023-01190-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Der Biomarker POLE in der Tumorpathologie.

    Lehmann, Ulrich / Stenzinger, Albrecht

    Pathologie (Heidelberg, Germany)

    2023  Volume 45, Issue 1, Page(s) 67–68

    Title translation The biomarker POLE in tumor pathology.
    MeSH term(s) Humans ; Biomarkers ; Mutation ; Neoplasms/diagnosis
    Chemical Substances Biomarkers
    Language German
    Publishing date 2023-12-05
    Publishing country Germany
    Document type Journal Article
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-023-01284-4
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  4. Article ; Online: Der Biomarker IDH1/2 in der Tumorpathologie.

    Lehmann, Ulrich / Stenzinger, Albrecht

    Pathologie (Heidelberg, Germany)

    2023  Volume 44, Issue 5, Page(s) 318–319

    Title translation The IDH1/2 biomarker in tumor pathology.
    MeSH term(s) Humans ; Biomarkers, Tumor/genetics ; Neoplasms/diagnosis ; Isocitrate Dehydrogenase/genetics
    Chemical Substances Biomarkers, Tumor ; Isocitrate Dehydrogenase (EC 1.1.1.41) ; IDH1 protein, human (EC 1.1.1.42.)
    Language German
    Publishing date 2023-05-30
    Publishing country Germany
    Document type Journal Article
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-023-01199-0
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  5. Article: CDH1

    Bücker, Lara / Lehmann, Ulrich

    Cancers

    2022  Volume 14, Issue 18

    Abstract: Epigenetic inactivation of a tumor suppressor gene by aberrant DNA methylation is a well-established defect in human tumor cells, complementing genetic inactivation by mutation (germline or somatic). In human breast cancer, aberrant gene methylation has ... ...

    Abstract Epigenetic inactivation of a tumor suppressor gene by aberrant DNA methylation is a well-established defect in human tumor cells, complementing genetic inactivation by mutation (germline or somatic). In human breast cancer, aberrant gene methylation has diagnostic, prognostic, and predictive potential. A prominent example is the hypermethylation of the
    Language English
    Publishing date 2022-09-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14184377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Das molekularpathologische Brevier: was heißt: „hybrid capture“,„anchored multiplex PCR“ und amplikonbasiert?

    Lehmann, Ulrich / Stenzinger, Albrecht

    Der Pathologe

    2022  Volume 43, Issue 3, Page(s) 229–230

    Title translation The molecular pathology breviary: what do hybrid capture, anchored multiplex PCR and amplicon-based mean?
    MeSH term(s) High-Throughput Nucleotide Sequencing ; Multiplex Polymerase Chain Reaction ; Pathology, Molecular
    Language German
    Publishing date 2022-01-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 135954-x
    ISSN 1432-1963 ; 0172-8113
    ISSN (online) 1432-1963
    ISSN 0172-8113
    DOI 10.1007/s00292-021-01036-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1543: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Das molekularpathologische Brevier: Was heißt: „WGS, WES, Transkriptom, RNAseq“?

    Lehmann, Ulrich / Stenzinger, Albrecht

    Pathologie (Heidelberg, Germany)

    2022  Volume 43, Issue 4, Page(s) 317–318

    Title translation The molecular pathology breviary: What do "WGS, WES, transcriptome, RNAseq" mean?
    MeSH term(s) Exome ; Pathology, Molecular ; Transcriptome/genetics ; Whole Exome Sequencing
    Language German
    Publishing date 2022-03-08
    Publishing country Germany
    Document type Journal Article
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-022-01058-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Weiterentwicklung der Prognoseverfahren der Verkehrslärmschutzverordnung (16. BlmSchV)

    Maire, Wolf / Lehmann, Ulrich

    besonders überwachtes Gleis (BüG), feste Fahrbahnen ; Forschungsbericht 29854266

    (Texte / Umweltbundesamt ; [20]03,60 ; Umweltforschungsplan des Bundesministeriums für Umwelt, Naturschutz und Reaktorsicherheit)

    2003  

    Author's details von Wolfgang Maire ; Ulrich Lehmann. Umweltbundesamt. [Durchführende Inst. Ingenieurgemeinschaft Bonk-Maire-Hoppmann GbR. Red.: Fachgebiet I 3.4]
    Series title Texte / Umweltbundesamt ; [20]03,60
    Umweltforschungsplan des Bundesministeriums für Umwelt, Naturschutz und Reaktorsicherheit
    Collection
    Language German
    Size 350 S. in getr. Zählung : Ill., graph. Darst., 30 cm
    Publisher Umweltbundesamt
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT014028026
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    044/486 available for loan (reading room) Freihandmagazin (U1)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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  9. Article ; Online: Das molekularpathologische Brevier: Lesetiefe und Coverage in der NGS-Analytik.

    Lehmann, Ulrich / Stenzinger, Albrecht

    Der Pathologe

    2021  Volume 43, Issue 1, Page(s) 65–66

    Title translation The molecular pathology breviary: read depth and coverage in NGS analysis.
    MeSH term(s) Genomics ; High-Throughput Nucleotide Sequencing ; Pathology, Molecular ; Sequence Analysis, DNA
    Language German
    Publishing date 2021-10-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 135954-x
    ISSN 1432-1963 ; 0172-8113
    ISSN (online) 1432-1963
    ISSN 0172-8113
    DOI 10.1007/s00292-021-01009-5
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1543: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Next Generation Sequencing in der Pathologie : Anwendungen und methodische Herausforderungen.

    Lehmann, Ulrich / Jung, Andreas

    Der Pathologe

    2021  Volume 42, Issue 4, Page(s) 363–368

    Abstract: The enormous increase in sequencing capacity due to the development of next generation sequencing technologies opens up new opportunities in the fields of histopathology, research, and diagnostics, but also poses huge challenges.The identification of ... ...

    Title translation Next generation sequencing in histopathology : Applications and methodological challenges.
    Abstract The enormous increase in sequencing capacity due to the development of next generation sequencing technologies opens up new opportunities in the fields of histopathology, research, and diagnostics, but also poses huge challenges.The identification of genomic aberrations (point mutations, small insertions and deletions, fusion transcripts, and tumor mutation burden (TMB)) have already become a reliable part of routine molecular diagnostics. This will be supplemented by additional applications, namely gene amplifications, microsatellite instability, genomic signatures like homologous recombination deficiency (HRD), mRNA expression patterns, B‑ and T‑cell clonality, and DNA methylation. Challenges in preanalytics and the evaluation of assay sensitivity and specificity as well as proper curation of identified aberrations, which requires a new type of specialist, are presented and discussed.
    MeSH term(s) Biomarkers, Tumor ; Gene Amplification ; High-Throughput Nucleotide Sequencing ; Humans ; Microsatellite Instability ; Mutation
    Chemical Substances Biomarkers, Tumor
    Language German
    Publishing date 2021-06-25
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 135954-x
    ISSN 1432-1963 ; 0172-8113
    ISSN (online) 1432-1963
    ISSN 0172-8113
    DOI 10.1007/s00292-021-00953-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1543: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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