Article: Aging reduces motivation through decreased
bioRxiv : the preprint server for biology
2023
Abstract: Age-associated reduced motivation is a hallmark of neuropsychiatric disorders in the elderly. In our rapidly aging societies, it is critical to keep motivation levels high enough to promote healthspan and lifespan. However, how motivation is reduced ... ...
| Abstract | Age-associated reduced motivation is a hallmark of neuropsychiatric disorders in the elderly. In our rapidly aging societies, it is critical to keep motivation levels high enough to promote healthspan and lifespan. However, how motivation is reduced during aging remains unknown. Here, we used multiple mouse models to evaluate motivation and related affective states in young and old mice. We also compared the effect of social isolation, a common stressor, to those of aging. We found that both social isolation and aging decreased motivation in mice, but that |
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| Language | English |
| Publishing date | 2023-01-24 |
| Publishing country | United States |
| Document type | Preprint |
| DOI | 10.1101/2023.01.19.524624 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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