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  1. Article: Diagnostic value of integrated

    Zeng, Yuping / Leng, Xiaoming / Liao, Hengbin / Jiang, Guihua / Chen, Ping

    Prostate international

    2022  Volume 10, Issue 2, Page(s) 108–116

    Abstract: Objective: To assess the diagnostic value of fluorine 18 (: Materials and methods: The study enrolled 29 patients with suspected PCa preoperatively who underwent : Results: Of the 48 suspected PCa lesions in 29 patients, 38 were pathologically ... ...

    Abstract Objective: To assess the diagnostic value of fluorine 18 (
    Materials and methods: The study enrolled 29 patients with suspected PCa preoperatively who underwent
    Results: Of the 48 suspected PCa lesions in 29 patients, 38 were pathologically diagnosed with clinically significant PCa and 10 with nonprostate cancer (non-PCa) lesions. Compared with the pathological results,
    Conclusion: The diagnostic value of
    Language English
    Publishing date 2022-03-28
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2711928-2
    ISSN 2287-903X ; 2287-8882
    ISSN (online) 2287-903X
    ISSN 2287-8882
    DOI 10.1016/j.prnil.2022.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pelvic Plexiform Schwannoma on 18F-FDG PET/MRI.

    Zeng, Yuping / Luo, Jiandong / Nie, Jieyu / Leng, Xiaoming

    Clinical nuclear medicine

    2021  Volume 47, Issue 1, Page(s) 63–65

    Abstract: Abstract: Plexiform schwannoma (PS), a subtype of schwannoma, is a rare benign nerve sheath tumor characterized by a multinodular plexiform growth pattern. It is usually confined to the head and neck or skin. Pelvic PS is an extremely rare occurrence ... ...

    Abstract Abstract: Plexiform schwannoma (PS), a subtype of schwannoma, is a rare benign nerve sheath tumor characterized by a multinodular plexiform growth pattern. It is usually confined to the head and neck or skin. Pelvic PS is an extremely rare occurrence and signifies a challenge for the imaging diagnosis. In this work, we present a 42-year-old woman with pelvic PS, who was initially suspected of malignant tumor on 18F-FDG PET/MRI but confirmed as PS by postoperative pathology. We consider that this case would contribute to the literature and provide a further insight into diagnosing this kind of rare tumor.
    MeSH term(s) Adult ; Female ; Fluorodeoxyglucose F18 ; Humans ; Magnetic Resonance Imaging ; Nerve Sheath Neoplasms ; Neurilemmoma/diagnostic imaging ; Positron-Emission Tomography
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1276: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Imaging Diagnosis of Epithelioid Hemangioendothelioma in Thoracic Vertebrae and Liver.

    Zeng, Yuping / Leng, Xiaoming / Chen, Ping / Luo, Jiandong / Zhou, Zhiyang

    The Annals of thoracic surgery

    2019  Volume 109, Issue 6, Page(s) e407–e410

    Abstract: Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor of uncertain biologic behavior. Most cases come out as a single lesion of the soft tissue but also may appear in the lung, liver, and other locations. EHE in bone, especially in thoracic ... ...

    Abstract Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor of uncertain biologic behavior. Most cases come out as a single lesion of the soft tissue but also may appear in the lung, liver, and other locations. EHE in bone, especially in thoracic vertebrae, is an extremely rare occurrence and signifies a challenge for the imaging diagnosis. This paper presents a rare case of EHE occurring in thoracic vertebrae and liver revealed by fluoride-18-fluorodeoxyglucose-positron emission tomography and magnetic resonance imaging to provide a better understanding of its clinical application and further insight into diagnosing a rare thoracic tumor.
    MeSH term(s) Adult ; Diagnosis, Differential ; Hemangioendothelioma, Epithelioid/diagnosis ; Humans ; Liver ; Magnetic Resonance Imaging ; Male ; Neoplasms, Vascular Tissue/diagnosis ; Positron Emission Tomography Computed Tomography/methods ; Rare Diseases ; Thoracic Vertebrae
    Language English
    Publishing date 2019-11-30
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2019.10.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 252: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture.

    Han, Xiaorui / Leng, Xiaoming / Zhao, Man / Wu, Mei / Chen, Amei / Hong, Guoju / Sun, Ping

    Bioscience reports

    2017  Volume 37, Issue 6

    Abstract: Disc nucleus pulposus (NP) matrix homeostasis is important for normal disc function. Mechanical overloading seriously decreases matrix synthesis and increases matrix degradation. The present study aims to investigate the effects of resveratrol on disc NP ...

    Abstract Disc nucleus pulposus (NP) matrix homeostasis is important for normal disc function. Mechanical overloading seriously decreases matrix synthesis and increases matrix degradation. The present study aims to investigate the effects of resveratrol on disc NP matrix homeostasis under a relatively high-magnitude mechanical compression and the potential mechanism underlying this process. Porcine discs were perfusion-cultured and subjected to a relatively high-magnitude mechanical compression (1.3 MPa at a frequency of 1.0 Hz for 2 h once per day) for 7 days in a mechanically active bioreactor. The non-compressed discs were used as controls. Resveratrol was added along with culture medium to observe the effects of resveratrol on NP matrix synthesis under mechanical load respectively. NP matrix synthesis was evaluated by histology, biochemical content (glycosaminoglycan (GAG) and hydroxyproline (HYP)), and expression of matrix macromolecules (aggrecan and collagen II). Results showed that this high-magnitude mechanical compression significantly decreased NP matrix content, indicated by the decreased staining intensity of Alcian Blue and biochemical content (GAG and HYP), and the down-regulated expression of NP matrix macromolecules (aggrecan and collagen II). Further analysis indicated that resveratrol partly stimulated NP matrix synthesis and increased activity of the PI3K/Akt pathway in a dose-dependent manner under mechanical compression. Together, resveratrol is beneficial for disc NP matrix synthesis under mechanical overloading, and the activation of the PI3K/Akt pathway may participate in this regulatory process. Resveratrol may be promising to regenerate mechanical overloading-induced disc degeneration.
    MeSH term(s) Aggrecans/genetics ; Aggrecans/metabolism ; Animals ; Collagen/genetics ; Collagen/metabolism ; Culture Media ; Dose-Response Relationship, Drug ; Glycosaminoglycans/analysis ; Humans ; Hydroxyproline/analysis ; Intervertebral Disc/drug effects ; Intervertebral Disc/physiology ; Male ; Nucleus Pulposus/drug effects ; Organ Culture Techniques ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Regeneration ; Stilbenes/pharmacology ; Stress, Mechanical ; Swine
    Chemical Substances Aggrecans ; Culture Media ; Glycosaminoglycans ; Stilbenes ; Collagen (9007-34-5) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; resveratrol (Q369O8926L) ; Hydroxyproline (RMB44WO89X)
    Language English
    Publishing date 2017-12-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 764946-0
    ISSN 1573-4935 ; 0144-8463
    ISSN (online) 1573-4935
    ISSN 0144-8463
    DOI 10.1042/BSR20171319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1676: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Conference proceedings: T1rho/T2 mapping in MRI: a novel radiographic technology for determination of articular cartilage denaturalization with osteonecrosis of femoral head

    Han, Xiaorui / Hong, Guoju / Zhao, Man / Chen, Leilei / Leng, Xiaoming

    2017  , Page(s) IN12–1194

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2017
    Keywords Medizin, Gesundheit ; T1rho/T2 mapping ; osteonecrosis ; cartilage denaturalization ; ARCO stage
    Publishing date 2017-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/17dkou015
    Database German Medical Science

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  6. Conference proceedings: Early cartilage denaturalization with bone marrow edema in osteonecrosis of femoral head: evaluation by T1rho and T2 mapping MRI imaging-a pilot study

    Han, Xiaorui / Hong, Guoju / Zhao, Man / Liu, Yu / Leng, Xiaoming

    2017  , Page(s) IN14–1465

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2017
    Keywords Medizin, Gesundheit ; T1rho/T2 mapping ; bone marrow edema ; osteonecrosis ; cartilage denaturalization ; ARCO stage
    Publishing date 2017-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/17dkou039
    Database German Medical Science

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  7. Article ; Online: T

    Han, Xiaorui / Hong, Guoju / Chen, Leilei / Zhao, Man / Guo, Yuan / Xu, Ling / Wu, Mei / Leng, Xiaoming / Sun, Ping

    Journal of magnetic resonance imaging : JMRI

    2018  Volume 49, Issue 3, Page(s) 760–767

    Abstract: Background: In the future, biochemical MRI might provide a valuable noninvasive quantitative analysis of the biochemical composition of cartilage in osteonecrosis of the femoral head (ONFH).: Purpose: To investigate the diagnostic performance of T: ...

    Abstract Background: In the future, biochemical MRI might provide a valuable noninvasive quantitative analysis of the biochemical composition of cartilage in osteonecrosis of the femoral head (ONFH).
    Purpose: To investigate the diagnostic performance of T
    Study type: Prospective.
    Subjects: Forty-seven patients with ONFH (stage I to III according to the ARCO criteria) and 24 volunteers (control group) were recruited for the prospective study.
    Sequence: Conventional MRI, multiple echo recalled gradient echo (MERGE), and T
    Assessment: Pseudocolor images and MERGE images were combined in the AW4.5 workstation. The region of interest (ROI) of the hip cartilage was 4-6 mm². The sagittal T
    Statistical tests: One-way analysis of variance (ANOVA), LSD t-tests, Pearson correlation analysis, and receiver operator characteristic (ROC) curves. The significance level was set at P < 0.05.
    Results: The T
    Data conclusion: Both T
    Level of evidence: 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:760-767.
    MeSH term(s) Adolescent ; Adult ; Algorithms ; Cartilage, Articular/pathology ; Case-Control Studies ; Female ; Femur Head/diagnostic imaging ; Humans ; Image Processing, Computer-Assisted/methods ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Osteonecrosis/diagnostic imaging ; Prospective Studies ; ROC Curve ; Reproducibility of Results ; Young Adult
    Language English
    Publishing date 2018-11-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.26267
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    Zs.A 3648: Show issues Location:
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    Zs.MO 236: Show issues

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  8. Conference proceedings: T1rho/T2 mapping MRI and 3D intraoperative micro-CT for investigating relationship between cartilage degeneration and trabecular structure in osteonecrosis of femoral head

    Han, Xiaorui / Hong, Guoju / Chen, Leilei / Zhao, Man / Liu, Yu / Leng, Xiaoming

    2017  , Page(s) IN12–1162

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2017
    Keywords Medizin, Gesundheit ; T1rho/T2 mapping ; microCT ; osteonecrosis ; cartilage degeneration ; trabecular structure
    Publishing date 2017-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/17dkou017
    Database German Medical Science

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  9. Conference proceedings: Evaluation parameters of microcirculation and fat quality in osteonecrosis of femoral head by using intra-voxel incoherent motion and etry/the least-squares estimation: a prospective pilot study

    Han, Xiaorui / Hong, Guoju / Zhao, Man / Liu, Yu / He, Wei / Leng, Xiaoming

    2017  , Page(s) IN12–1169

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2017
    Keywords Medizin, Gesundheit ; microcirculation ; fat quality ; osteonecrosis ; IVIM ; IDEAL
    Publishing date 2017-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/17dkou014
    Database German Medical Science

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