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  1. Article ; Online: Radiographic case report of a heart transplanted patient suffering from COVID-19

    Leona S. Alizadeh / Moritz H. Albrecht / Christian Booz

    Heliyon, Vol 7, Iss 4, Pp e06688- (2021)

    2021  

    Abstract: In context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients with certain comorbidities and high age, as well as male sex are considered to represent the risk group for severe course of disease. Corona-virus disease 2019 (COVID-19) ...

    Abstract In context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients with certain comorbidities and high age, as well as male sex are considered to represent the risk group for severe course of disease. Corona-virus disease 2019 (COVID-19) typical CT-patterns include bilateral, peripheral ground glass opacity (GGO), septal thickening, bronchiectasis, consolidation as well as associated pleural effusion. We report a 77-year-old heart transplanted patient with confirmed COVID-19 infection and coronary heart disease, diabetes type II and other risk factors. Notably, only slight clinical symptoms were reported and repeated computed tomography (CT) scans showed an atypical course of CT findings during his hospitalization.
    Keywords COVID-19 ; Heart transplantation ; Thorax ; Multidetector computed tomography ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Case report of rare congenital cardiovascular anomalies associated with truncus arteriosus type 2

    Leona S. Alizadeh / Vitali Koch / Leon D. Grünewald / Ibrahim Yel / Daniel Mathies / Dominic Rauschning / Thomas J. Vogl / Christian Booz

    Heliyon, Vol 8, Iss 10, Pp e11033- (2022)

    2022  

    Abstract: Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to ...

    Abstract Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to be surgically treated. Thus, it is of high importance to understand this congenital cardiovascular disease and associated complications, to improve life expectancy and outcome of these patients. We recently came across a newborn female patient with a rare complex case of persistent TA type 2 associated with further complex cardiovascular anomalies, who received a contrast enhanced CT scan on the 3 rd day post-partum, showing complex cardiovascular abnormalities that were ultimately incompatible with life.
    Keywords Truncus arteriosus ; Fetal heart ; Cardiovascular diseases ; Heart defects ; Congenital ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 616
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Diagnosis of Uric Acid-Based Urine Sedimentation in the Bladder Using Dual-Energy CT

    Christian Booz / Ibrahim Yel / Julian L. Wichmann / Simon S. Martin / Vitali Koch / Leon D. Gruenewald / Leona S. Alizadeh / Thomas J. Vogl / Tommaso D’Angelo

    Diagnostics, Vol 13, Iss 542, p

    2023  Volume 542

    Abstract: Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for ... ...

    Abstract Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for urinary stones. Depending on the composition, urine sedimentation and stones can be treated medically by alkalinisation of the urine with potassium sodium hydrogen citrate in the case of uric acid-based sedimentation/stones. Due to technical developments and improved material differentiation and characterisation in CT imaging, dual-energy CT allows for differentiation of uric acid from calcium, which can be used for sedimentation/stone composition analysis. Subsequently, treatment decisions can be made based on the findings in dual-energy CT.
    Keywords dual energy CT ; urine sedimenation ; uric acid ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Dual-Energy CT in Cardiothoracic Imaging

    Leona S. Alizadeh / Thomas J. Vogl / Stephan S. Waldeck / Daniel Overhoff / Tommaso D’Angelo / Simon S. Martin / Ibrahim Yel / Leon D. Gruenewald / Vitali Koch / Florian Fulisch / Christian Booz

    Diagnostics, Vol 13, Iss 2116, p

    Current Developments

    2023  Volume 2116

    Abstract: This article describes the technical principles and clinical applications of dual-energy computed tomography (DECT) in the context of cardiothoracic imaging with a focus on current developments and techniques. Since the introduction of DECT, different ... ...

    Abstract This article describes the technical principles and clinical applications of dual-energy computed tomography (DECT) in the context of cardiothoracic imaging with a focus on current developments and techniques. Since the introduction of DECT, different vendors developed distinct hard and software approaches for generating multi-energy datasets and multiple DECT applications that were developed and clinically investigated for different fields of interest. Benefits for various clinical settings, such as oncology, trauma and emergency radiology, as well as musculoskeletal and cardiovascular imaging, were recently reported in the literature. State-of-the-art applications, such as virtual monoenergetic imaging (VMI), material decomposition, perfused blood volume imaging, virtual non-contrast imaging (VNC), plaque removal, and virtual non-calcium (VNCa) imaging, can significantly improve cardiothoracic CT image workflows and have a high potential for improvement of diagnostic accuracy and patient safety.
    Keywords multidetector computed tomography ; cardiovascular imaging ; cardiac Imaging ; dual-energy X-ray absorptiometry ; dual-energy computed tomography ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  5. Article ; Online: A case of myocarditis after COVID-19 vaccination

    Leona S. Alizadeh / Vitali Koch / Ibrahim Yel / Leon D. Grünewald / Daniel Mathies / Simon Martin / Thomas J. Vogl / Dominic Rauschning / Christian Booz

    Heliyon, Vol 8, Iss 6, Pp e09537- (2022)

    incidental or consequential?

    2022  

    Abstract: Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart ... ...

    Abstract Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart failure. We report a case of a 29-year-old man who presented with fever and retrosternal pain after receiving SARS-CoV-2 vaccine. Cardiac magnetic resonance imaging and laboratory data revealed typical findings of acute myocarditis.
    Keywords Myocarditis ; Vaccination ; COVID-19 ; MRI ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  6. Article ; Online: Accuracy and precision of volumetric bone mineral density assessment using dual-source dual-energy versus quantitative CT

    Vitali Koch / Nils Große Hokamp / Moritz H. Albrecht / Leon D. Gruenewald / Ibrahim Yel / Jan Borggrefe / Stefan Wesarg / Katrin Eichler / Iris Burck / Tatjana Gruber-Rouh / Lukas Lenga / Thomas J. Vogl / Simon S. Martin / Julian L. Wichmann / Renate M. Hammerstingl / Leona S. Alizadeh / Christoph Mader / Nicole A. Huizinga / Tommaso D’Angelo /
    Giorgio Ascenti / Silvio Mazziotti / Christian Booz

    European Radiology Experimental, Vol 5, Iss 1, Pp 1-

    a phantom study

    2021  Volume 10

    Abstract: Abstract Background Dual-source dual-energy computed tomography (DECT) offers the potential for opportunistic osteoporosis screening by enabling phantomless bone mineral density (BMD) quantification. This study sought to assess the accuracy and precision ...

    Abstract Abstract Background Dual-source dual-energy computed tomography (DECT) offers the potential for opportunistic osteoporosis screening by enabling phantomless bone mineral density (BMD) quantification. This study sought to assess the accuracy and precision of volumetric BMD measurement using dual-source DECT in comparison to quantitative CT (QCT). Methods A validated spine phantom consisting of three lumbar vertebra equivalents with 50 (L1), 100 (L2), and 200 mg/cm3 (L3) calcium hydroxyapatite (HA) concentrations was scanned employing third-generation dual-source DECT and QCT. While BMD assessment based on QCT required an additional standardised bone density calibration phantom, the DECT technique operated by using a dedicated postprocessing software based on material decomposition without requiring calibration phantoms. Accuracy and precision of both modalities were compared by calculating measurement errors. In addition, correlation and agreement analyses were performed using Pearson correlation, linear regression, and Bland-Altman plots. Results DECT-derived BMD values differed significantly from those obtained by QCT (p < 0.001) and were found to be closer to true HA concentrations. Relative measurement errors were significantly smaller for DECT in comparison to QCT (L1, 0.94% versus 9.68%; L2, 0.28% versus 5.74%; L3, 0.24% versus 3.67%, respectively). DECT demonstrated better BMD measurement repeatability compared to QCT (coefficient of variance < 4.29% for DECT, < 6.74% for QCT). Both methods correlated well to each other (r = 0.9993; 95% confidence interval 0.9984–0.9997; p < 0.001) and revealed substantial agreement in Bland-Altman plots. Conclusions Phantomless dual-source DECT-based BMD assessment of lumbar vertebra equivalents using material decomposition showed higher diagnostic accuracy compared to QCT.
    Keywords Bone density ; Dual-energy computed tomography ; Osteoporosis ; Phantoms (imaging) ; Tomography (x-ray computed) ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 541
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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