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  1. Article ; Online: Editorial: the prevalence of Helicobacter pylori infection worldwide-knowns and unknowns.

    Tsipotis, E / Leontiadis, G I

    Alimentary pharmacology & therapeutics

    2018  Volume 47, Issue 9, Page(s) 1330–1331

    MeSH term(s) Helicobacter Infections ; Helicobacter pylori ; Humans ; Prevalence
    Language English
    Publishing date 2018-04-05
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.14609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The Canadian Association of Gastroenterology's New Climate Change Committee.

    Leddin, Desmond / Singh, Harminder / Armstrong, David / Cheyne, Kelsey / Galts, Ciaran / Igoe, John / Leontiadis, Grigorios / McGrath, Jerry / Pray, Cara / Sadowski, Daniel / Shahidi, Neal / Sinclair, Paul / Tse, Frances / Yanofsky, Russell

    Journal of the Canadian Association of Gastroenterology

    2024  Volume 7, Issue 2, Page(s) 135–136

    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Editorial
    ZDB-ID 2940642-0
    ISSN 2515-2092 ; 2515-2084
    ISSN (online) 2515-2092
    ISSN 2515-2084
    DOI 10.1093/jcag/gwae006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19

    Tse, Frances / Borgaonkar, Mark / Leontiadis, Grigorios

    Journal of the Canadian Association of Gastroenterology, 3(3):147-149

    Advice from the Canadian Association of Gastroenterology for Endoscopy Facilities, as of March 16, 2020

    2020  

    Abstract: The above guidance (Figure 1) reflects the current limited evidence available, but further guidance may be required as the situation rapidly evolves.CAG would like to highlight an important article by Repici et al. who had first hand experience with ... ...

    Abstract The above guidance (Figure 1) reflects the current limited evidence available, but further guidance may be required as the situation rapidly evolves.CAG would like to highlight an important article by Repici et al. who had first hand experience with performing endoscopic procedures during this outbreak.1 This article discussed measures, with specific focus on patient management and risk stratification based on procedural types and patient-related risk factors, personal protection equipment (PPE) and process for wearing and removing PPE, which have been implemented in their hospitals to reduce dissemination of COVID-19 infection. It is important to note that the proposed measures are based on current limited understanding of the incubation period, mechanisms of transmission, clinical course and the duration of infectivity. As well, the evidence supporting the use of these measures is largely based on prior experience from other coronaviruses (e.g., SARS-CoV and MERS-CoV). Figure 1 summarizes CAG guidance on infection prevention and control for COVID-19 when performing endoscopic procedures (as of March 16, 2020).
    Keywords COVID-19 ; covid19
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: PPI co-therapy did not adversely affect outcomes in clopidogrel users.

    Leontiadis, G I / Howden, C W

    Alimentary pharmacology & therapeutics

    2012  Volume 35, Issue 2, Page(s) 313–314

    MeSH term(s) Cytochrome P-450 Enzyme Inhibitors ; Female ; Gastroesophageal Reflux/drug therapy ; Humans ; Male ; Myocardial Infarction/chemically induced ; Platelet Aggregation Inhibitors/adverse effects ; Proton Pump Inhibitors/adverse effects ; Ticlopidine/analogs & derivatives
    Chemical Substances Cytochrome P-450 Enzyme Inhibitors ; Platelet Aggregation Inhibitors ; Proton Pump Inhibitors ; Ticlopidine (OM90ZUW7M1)
    Language English
    Publishing date 2012-01
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/j.1365-2036.2011.04935.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: Sequential therapy--more studies are still required.

    Merali, A / Leontiadis, G I

    Alimentary pharmacology & therapeutics

    2012  Volume 35, Issue 1, Page(s) 194–5; discussion 195–6

    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Female ; Helicobacter Infections/drug therapy ; Humans ; Male ; Proton Pump Inhibitors/administration & dosage
    Chemical Substances Anti-Bacterial Agents ; Proton Pump Inhibitors
    Language English
    Publishing date 2012-01
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/j.1365-2036.2011.04894.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Commentary: What is the optimal PPI dosing following endoscopic haemostasis in acute ulcer bleeding?

    Leontiadis, G I / Barkun, A N

    Alimentary pharmacology & therapeutics

    2012  Volume 35, Issue 11, Page(s) 1351–2; author reply 1352

    MeSH term(s) 2-Pyridinylmethylsulfinylbenzimidazoles/administration & dosage ; Female ; Hemostasis, Endoscopic/methods ; Humans ; Male ; Peptic Ulcer Hemorrhage/prevention & control ; Proton Pump Inhibitors/administration & dosage ; Vasoconstrictor Agents/therapeutic use
    Chemical Substances 2-Pyridinylmethylsulfinylbenzimidazoles ; Proton Pump Inhibitors ; Vasoconstrictor Agents
    Language English
    Publishing date 2012-06
    Publishing country England
    Document type Comment ; Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/j.1365-2036.2012.05087.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Interventions to improve the quality of screening-related colonoscopy: protocol for a systematic review and network meta-analysis of randomised controlled trials.

    Khan, Rishad / Vaska, Marcus / Ruan, Yibing / Bansal, Rishi / Gimpaya, Nikko / Scaffidi, Michael A / Brenner, Darren / Leontiadis, G I / Grover, Samir C / Forbes, Nauzer

    BMJ open

    2022  Volume 12, Issue 11, Page(s) e061855

    Abstract: Introduction: Colonoscopy quality can vary depending on endoscopist-related factors. Quality indicators, such as adenoma detection rate (ADR), have been adopted to reduce variations in care. Several interventions aim to improve ADR, but these fall into ... ...

    Abstract Introduction: Colonoscopy quality can vary depending on endoscopist-related factors. Quality indicators, such as adenoma detection rate (ADR), have been adopted to reduce variations in care. Several interventions aim to improve ADR, but these fall into several domains that have traditionally been difficult to compare. We will conduct a systematic review and network meta-analysis of randomised controlled trials evaluating the efficacies of interventions to improve colonoscopy quality and report our findings according to clinically relevant interventional domains.
    Methods and analysis: We will search MEDLINE (Ovid), PubMed, EMBASE, CINAHL, Web of Science, Scopus and Evidence-Based Medicine from inception to September 2022. Four reviewers will screen for eligibility and abstract data in parallel, with two accordant entries establishing agreement and with any discrepancies resolved by consensus. The primary outcome will be ADR. Two authors will independently conduct risk of bias assessments. The analyses of the network will be conducted under a Bayesian random-effects model using Markov-chain Monte-Carlo simulation, with 10 000 burn-ins and 100 000 iterations. We will calculate the ORs and corresponding 95% credible intervals of network estimates with a consistency model. We will report the impact of specific interventions within each domain against standard colonoscopy. We will perform a Bayesian random-effects pairwise meta-analysis to assess heterogeneity based on the I
    Ethics and dissemination: Our study does not require research ethics approval given the lack of patient-specific data being collected. The results will be disseminated at national and international gastroenterology conferences and peer-reviewed journals.
    Prospero registration number: CRD42021291814.
    MeSH term(s) Humans ; Network Meta-Analysis ; Bayes Theorem ; Colonoscopy ; Bias ; Markov Chains ; Systematic Reviews as Topic ; Meta-Analysis as Topic
    Language English
    Publishing date 2022-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-061855
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  8. Article ; Online: Night-time intra-oesophageal bile and acid exposure in GERD patients failing PPI therapy.

    Leontiadis, G I / Tse, F

    Alimentary pharmacology & therapeutics

    2011  Volume 33, Issue 9, Page(s) 1068–9; author reply 1069

    MeSH term(s) Bile Reflux ; Circadian Rhythm ; Gastric Acid/physiology ; Gastroesophageal Reflux/drug therapy ; Humans ; Proton Pump Inhibitors/therapeutic use ; Research Design
    Chemical Substances Proton Pump Inhibitors
    Language English
    Publishing date 2011-05
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/j.1365-2036.2011.04623.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Systematic review of the symptom burden, quality of life impairment and costs associated with peptic ulcer disease.

    Barkun, Alan / Leontiadis, Grigorios

    The American journal of medicine

    2010  Volume 123, Issue 4, Page(s) 358–66.e2

    Abstract: Background: Management of peptic ulcer disease has improved over the past few decades. However, the widespread use of nonsteroidal anti-inflammatory drugs and low-dose acetylsalicylic acid means that the burden of peptic ulcer disease remains a relevant ...

    Abstract Background: Management of peptic ulcer disease has improved over the past few decades. However, the widespread use of nonsteroidal anti-inflammatory drugs and low-dose acetylsalicylic acid means that the burden of peptic ulcer disease remains a relevant issue.
    Methods: We systematically searched PubMed and EMBASE for articles published 1966-2007 that reported symptoms, impairment of well-being or health-related quality of life, and costs associated with peptic ulcer disease.
    Results: Thirty studies reported the prevalence of patient-reported gastrointestinal symptoms in individuals with endoscopically diagnosed symptomatic peptic ulcer disease. Average prevalence estimates, weighted by sample size, were 81% (95% confidence interval [CI], 77%-85%) for abdominal pain (11 studies), 81% (95% CI, 76%-85%) for pain specifically of epigastric origin (14 studies), and 46% (95% CI, 42%-50%) for heartburn or acid regurgitation (11 studies). On average, 29% (95% CI, 25%-34%) of patients with peptic ulcer disease presented with bleeding, often as the initial symptom (11 studies). Patients with peptic ulcer disease had significantly lower health-related quality of life than the general population, as measured by the Psychological General Well-Being index (P <.05; 7 studies) and the Short-Form-36 questionnaire (P <.05; 2 studies). Direct medical costs of peptic ulcer disease based on national estimates from several countries were USD163-866 per patient. The most costly aspects of peptic ulcer disease management were hospitalization and medication. Complicated peptic ulcer disease is particularly costly, estimated to be USD1883-25,444 per patient.
    Conclusion: Peptic ulcer disease significantly impairs well-being and aspects of health-related quality of life, and is associated with high costs for employers and health care systems.
    MeSH term(s) Humans ; Peptic Ulcer/chemically induced ; Peptic Ulcer/complications ; Peptic Ulcer/economics ; Quality of Life
    Language English
    Publishing date 2010-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2009.09.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: American Gastroenterological Association Institute Guideline on the Role of Upper Gastrointestinal Biopsy to Evaluate Dyspepsia in the Adult Patient in the Absence of Visible Mucosal Lesions.

    Yang, Yu-Xiao / Brill, Joel / Krishnan, Prashant / Leontiadis, Grigorios

    Gastroenterology

    2015  Volume 149, Issue 4, Page(s) 1082–1087

    MeSH term(s) Adult ; Age Factors ; Biopsy/standards ; Dyspepsia/etiology ; Dyspepsia/immunology ; Dyspepsia/pathology ; Dyspepsia/therapy ; Endoscopy, Gastrointestinal/standards ; Gastroenterology/standards ; Humans ; Immunocompromised Host ; Mucous Membrane/pathology ; Patient Selection ; Predictive Value of Tests ; Prognosis ; Reproducibility of Results ; Risk Factors ; Upper Gastrointestinal Tract/immunology ; Upper Gastrointestinal Tract/pathology ; Young Adult
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Journal Article ; Practice Guideline ; Review
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2015.07.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 572: Show issues

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