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  1. Artikel: Comment j’explore. Innovations technologiques récentes en scintigraphie de perfusion myocardique et maladie coronarienne.

    Lejeune, Thomas / Derwael, Céline / Bernard, Claire / Letesson, Gaetan / Daenen, Frédéric / Hustinx, Roland

    Revue medicale de Liege

    2023  Band 78, Heft 10, Seite(n) 580–585

    Abstract: Cardiovascular diseases represent the first cause of mortality in the world. Various exploration methods exist to prevent and diagnose them. Among them, cardiac scintigraphy holds a predominant place. There are various equipments and procedures for its ... ...

    Titelübersetzung Myocardial perfusion imaging and coronary artery disease : recent technological innovations.
    Abstract Cardiovascular diseases represent the first cause of mortality in the world. Various exploration methods exist to prevent and diagnose them. Among them, cardiac scintigraphy holds a predominant place. There are various equipments and procedures for its realization. We compared the practical aspects of using a conventional Anger camera (Symbia, Siemens) according to a two-days examination protocol with a dedicated cardio CzT camera (D-Spect, Spectrum Dynamics) according to a two-days protocol and a 360°SPECT/CT CzT camera (Veriton, Spectrum Dynamics) according to a one-day protocol. The use of CzT detectors allows a reduction of the activity injected to the patient and of the acquisition time in order to make this examination faster and less irradiating for the patient.
    Mesh-Begriff(e) Humans ; Coronary Artery Disease/diagnostic imaging ; Myocardial Perfusion Imaging/methods ; Inventions ; Tomography, Emission-Computed, Single-Photon/methods ; Gamma Cameras
    Sprache Französisch
    Erscheinungsdatum 2023-10-13
    Erscheinungsland Belgium
    Dokumenttyp English Abstract ; Practice Guideline
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Clinical added-value of 18FDG PET in neuroendocrine-merkel cell carcinoma.

    Belhocine, Tarik / Pierard, Gerald E / Frühling, Janos / Letesson, Gaëtan / Bolle, Stephanie / Hustinx, Roland / Dargent, Jean-Louis / Flamen, Patrick / Rigo, Pierre

    Oncology reports

    2006  Band 16, Heft 2, Seite(n) 347–352

    Abstract: Merkel cell carcinoma (MCC) is a rare and highly malignant skin cancer with neuroendocrine differentiation. We studied the potential value of 18FDG PET in the management of MCC. Eleven patients with MCC were examined by 18FDG PET and PET-CT for staging ... ...

    Abstract Merkel cell carcinoma (MCC) is a rare and highly malignant skin cancer with neuroendocrine differentiation. We studied the potential value of 18FDG PET in the management of MCC. Eleven patients with MCC were examined by 18FDG PET and PET-CT for staging purpose (n=4) or for detection of recurrence (n=7). Qualitative and quantitative interpretation of PET studies was performed routinely. 18FDG PET observations were compared to clinical and radiological findings. In 6 patients, PET findings were also compared to histology. In 7 patients, the 18FDG tumor uptake was compared to the MCC proliferative activity expressed by the Ki-67 index. 18FDG PET was contributive in 10/11 MCC patients. In 7 patients, 18FDG PET detected focal lesions or a disseminated stage of the disease including dermal, nodal and visceral metastases. In 3 patients, a normal 18FDG PET confirmed complete remission of disease. Most MCC patients exhibited highly 18FDG-avid sites suggestive of increased glucose metabolism. This imaging pattern was related to a high proliferative activity (Ki-67 index >50%). In 1 patient with a weakly proliferative nodal MCC (Ki-67<10%), a false negative result was yielded by metabolic imaging. In 4/11 patients, 18FDG PET revealed an unsuspected second neoplasm in addition to MCC. It is concluded that whole-body 18FDG PET may be useful in the management of MCC patients. However, a normal 18FDG PET aspect cannot rule out MCC with low proliferative activity.
    Mesh-Begriff(e) Aged ; Carcinoma, Merkel Cell/diagnostic imaging ; Carcinoma, Merkel Cell/pathology ; Cell Proliferation ; Female ; Fluorodeoxyglucose F18 ; Humans ; Ki-67 Antigen/analysis ; Male ; Middle Aged ; Neuroendocrine Tumors/diagnostic imaging ; Neuroendocrine Tumors/pathology ; Positron-Emission Tomography/methods ; Skin Neoplasms/diagnostic imaging ; Skin Neoplasms/pathology
    Chemische Substanzen Ki-67 Antigen ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Sprache Englisch
    Erscheinungsdatum 2006-08
    Erscheinungsland Greece
    Dokumenttyp Evaluation Studies ; Journal Article
    ZDB-ID 1222484-4
    ISSN 1791-2431 ; 1021-335X
    ISSN (online) 1791-2431
    ISSN 1021-335X
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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