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  1. Book ; Online ; Conference proceedings: Nutrition, Gut Microbiota and Immunity: Therapeutic Targets for IBD

    Lewis, J.D.

    79th Nestlé Nutrition Institute Workshop, New York, N.Y., September 2013

    (Nestlé Nutrition Institute Workshop Series ; Vol.79)

    2014  

    Series title Nestlé Nutrition Institute Workshop Series ; Vol.79
    Keywords Gastroenterology ; Nutrition ; Immunology
    Language English
    Size 1 Online-Ressource (XIV + 166 S.)
    Publisher S. Karger
    Publishing place Basel
    Document type Book ; Online ; Conference proceedings
    Note A comprehensive review
    HBZ-ID HT019543343
    ISBN 978-3-318-02670-2 ; 3-318-02670-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Contraction-associated maternal heart rate decelerations ameliorated by phenylephrine infusion in a hypovolemic but fluid-restricted patient with pneumonia and pericardial effusion.

    Lewis, J D / Archer, T L

    International journal of obstetric anesthesia

    2021  Volume 50, Page(s) 103250

    MeSH term(s) Deceleration ; Heart Rate ; Humans ; Hypovolemia ; Pericardial Effusion/therapy ; Phenylephrine/therapeutic use ; Pneumonia
    Chemical Substances Phenylephrine (1WS297W6MV)
    Language English
    Publishing date 2021-12-30
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1086024-1
    ISSN 1532-3374 ; 0959-289X
    ISSN (online) 1532-3374
    ISSN 0959-289X
    DOI 10.1016/j.ijoa.2021.103250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Preferential associations of soil fungal taxa under mixed compositions of eastern American tree species.

    Kutos, Steve / Barnes, Elle M / Bhutada, Arnav / Lewis, J D

    FEMS microbiology ecology

    2022  Volume 98, Issue 6

    Abstract: Soil fungi are vital to forest ecosystem function, in part through their role mediating tree responses to environmental factors, as well as directly through effects on resource cycling. While the distribution of soil fungi can vary with abiotic factors, ... ...

    Abstract Soil fungi are vital to forest ecosystem function, in part through their role mediating tree responses to environmental factors, as well as directly through effects on resource cycling. While the distribution of soil fungi can vary with abiotic factors, plant species identity is also known to affect community composition. However, the particular influence that a plant will have on its soil microbiota remains difficult to predict. Here, we paired amplicon sequencing and enzymatic assays to assess soil fungal composition and function under three tree species, Quercus rubra, Betula nigra, and Acer rubrum, planted individually and in all combinations in a greenhouse. We observed that fungal communities differed between each of the individual planted trees, suggesting at least some fungal taxa may associate preferentially with these tree species. Additionally, fungal community composition under mixed-tree plantings broadly differed from the individual planted trees, suggesting mixing of these distinct soil fungal communities. The data also suggest that there were larger enzymatic activities in the individual plantings as compared to all mixed-tree plantings which may be due to variations in fungal community composition. This study provides further evidence of the importance of tree identity on soil microbiota and functional changes to forest soils.
    MeSH term(s) Ecosystem ; Forests ; Fungi/classification ; Fungi/genetics ; Fungi/metabolism ; Microbiota/physiology ; Plants/metabolism ; Plants/microbiology ; Soil/chemistry ; Soil Microbiology ; Symbiosis/physiology ; Trees/microbiology
    Chemical Substances Soil
    Language English
    Publishing date 2022-05-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 283722-5
    ISSN 1574-6941 ; 0168-6496
    ISSN (online) 1574-6941
    ISSN 0168-6496
    DOI 10.1093/femsec/fiac056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Letter: the safety of herpes zoster vaccination for patients with inflammatory bowel disease being treated with anti-TNF medications-authors' reply.

    Khan, N / Lewis, J D

    Alimentary pharmacology & therapeutics

    2018  Volume 47, Issue 3, Page(s) 448

    MeSH term(s) Herpes Zoster ; Humans ; Inflammatory Bowel Diseases ; Tumor Necrosis Factor-alpha ; Vaccination
    Chemical Substances Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2018-01-31
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.14460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Predicting Microbiome Function Across Space Is Confounded by Strain-Level Differences and Functional Redundancy Across Taxa.

    Barnes, Elle M / Carter, Erin L / Lewis, J D

    Frontiers in microbiology

    2020  Volume 11, Page(s) 101

    Abstract: Variation in the microbiome among individual organisms may play a critical role in the relative susceptibility of those organisms to infection, disease, and death. However, predicting microbiome function is difficult because of spatial and temporal ... ...

    Abstract Variation in the microbiome among individual organisms may play a critical role in the relative susceptibility of those organisms to infection, disease, and death. However, predicting microbiome function is difficult because of spatial and temporal variation in microbial diversity, and taxonomic diversity is not predictive of microbiome functional diversity. Addressing this issue may be particularly important when addressing pandemic diseases, such as the global amphibian die-off associated with
    Language English
    Publishing date 2020-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2020.00101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Assembly of the amphibian microbiome is influenced by the effects of land‐use change on environmental reservoirs

    Barnes, Elle M. / Kutos, Steve / Naghshineh, Nina / Mesko, Marissa / You, Qing / Lewis, J. D.

    Environmental microbiology. 2021 Aug., v. 23, no. 8

    2021  

    Abstract: A growing focus in microbial ecology is understanding how beneficial microbiome function is created and maintained through various assembly mechanisms. This study explores the role of both the environment and disease in regulating the composition of ... ...

    Abstract A growing focus in microbial ecology is understanding how beneficial microbiome function is created and maintained through various assembly mechanisms. This study explores the role of both the environment and disease in regulating the composition of microbial species in the soil and on amphibian hosts. We compared the microbial communities of Plethodon cinereus salamanders along a land‐use gradient in the New York metropolitan area and paired these with associated soil cores. Additionally, we characterized the diversity of bacterial and fungal symbionts that putatively inhibit the pathogenic fungus Batrachochytrium dendrobatidis. We predicted that variation in skin microbial community composition would correlate with changes seen in the soil which functions as the regional species pool. We found that salamanders and soil share many microbial taxa but that these two communities exhibit differences in the relative abundances of the bacterial phyla Acidobacteria, Actinobacteria, and Proteobacteria and the fungal phyla Ascomycota and genus Basidiobolus. Microbial community composition varies with changes in land‐use associated factors creating site‐specific compositions. By employing a quantitative, null‐based assembly model, we identified that dispersal limitation, variable selection, and drift guide assembly of microbes onto their skin, creating high dissimilarity between individuals with likely consequences in disease preventative function.
    Keywords Acidobacteria ; Actinobacteria ; Ascomycota ; Basidiobolus ; Batrachochytrium dendrobatidis ; Plethodon cinereus ; Proteobacteria ; community structure ; fungi ; land use change ; metropolitan areas ; microbial communities ; microbiome ; models ; soil ; symbionts ; virulent strains ; New York
    Language English
    Dates of publication 2021-08
    Size p. 4595-4611.
    Publishing place John Wiley & Sons, Inc.
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2020213-1
    ISSN 1462-2920 ; 1462-2912
    ISSN (online) 1462-2920
    ISSN 1462-2912
    DOI 10.1111/1462-2920.15653
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Assembly of the amphibian microbiome is influenced by the effects of land-use change on environmental reservoirs.

    Barnes, Elle M / Kutos, Steve / Naghshineh, Nina / Mesko, Marissa / You, Qing / Lewis, J D

    Environmental microbiology

    2021  Volume 23, Issue 8, Page(s) 4595–4611

    Abstract: A growing focus in microbial ecology is understanding how beneficial microbiome function is created and maintained through various assembly mechanisms. This study explores the role of both the environment and disease in regulating the composition of ... ...

    Abstract A growing focus in microbial ecology is understanding how beneficial microbiome function is created and maintained through various assembly mechanisms. This study explores the role of both the environment and disease in regulating the composition of microbial species in the soil and on amphibian hosts. We compared the microbial communities of Plethodon cinereus salamanders along a land-use gradient in the New York metropolitan area and paired these with associated soil cores. Additionally, we characterized the diversity of bacterial and fungal symbionts that putatively inhibit the pathogenic fungus Batrachochytrium dendrobatidis. We predicted that variation in skin microbial community composition would correlate with changes seen in the soil which functions as the regional species pool. We found that salamanders and soil share many microbial taxa but that these two communities exhibit differences in the relative abundances of the bacterial phyla Acidobacteria, Actinobacteria, and Proteobacteria and the fungal phyla Ascomycota and genus Basidiobolus. Microbial community composition varies with changes in land-use associated factors creating site-specific compositions. By employing a quantitative, null-based assembly model, we identified that dispersal limitation, variable selection, and drift guide assembly of microbes onto their skin, creating high dissimilarity between individuals with likely consequences in disease preventative function.
    MeSH term(s) Amphibians ; Animals ; Bacteria/genetics ; Fungi/genetics ; Humans ; Microbiota ; Soil Microbiology
    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020213-1
    ISSN 1462-2920 ; 1462-2912
    ISSN (online) 1462-2920
    ISSN 1462-2912
    DOI 10.1111/1462-2920.15653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comparison of risk factors and outcomes of daptomycin-susceptible and -nonsusceptible vancomycin-resistant Enterococcus faecium infections in liver transplant recipients.

    Lewis, J D / Barros, A J / Sifri, C D

    Transplant infectious disease : an official journal of the Transplantation Society

    2018  Volume 20, Issue 3, Page(s) e12856

    Abstract: Background: Vancomycin-resistant Enterococcus faecium (VRE) infections are common in liver transplant recipients (LTRs). Daptomycin (DAP) is an important treatment for such infections; however, DAP-nonsusceptible VRE (DNS-VRE) are increasingly frequent. ...

    Abstract Background: Vancomycin-resistant Enterococcus faecium (VRE) infections are common in liver transplant recipients (LTRs). Daptomycin (DAP) is an important treatment for such infections; however, DAP-nonsusceptible VRE (DNS-VRE) are increasingly frequent. The purpose of this study was to compare clinical characteristics and outcomes of LTRs with infections due to DNS-VRE and DAP-susceptible VRE (DS-VRE).
    Methods: A single center, retrospective review of patients who underwent liver transplantation between January 1, 2010 and December 31, 2015 and developed infections due to DS-VRE or DNS-VRE post transplant was performed. Patients with DNS-VRE and DS-VRE infections were compared using univariate and logistic regression analysis.
    Results: Fourteen LTRs developed DNS-VRE and 20 LTRs developed DS-VRE infection post-transplantation. No significant differences were observed in demographics, model for end-stage liver disease (MELD) scores, causes of end-stage liver disease, or rate of pre-transplant perirectal VRE colonization between groups. Bleeding complications and renal replacement therapy were more common in the DNS-VRE group than in the DS-VRE group. The duration of transplant hospitalization and post-transplant intensive care unit (ICU) admission was longer in the DNS-VRE group than in the DS-VRE group. The 30-day and 6-month mortality rate associated with DNS-VRE infection was similar to that associated with DS-VRE infection.
    Conclusions: Liver transplant recipients who develop DNS-VRE infection have higher bleeding complications and longer, more complex hospitalizations compared to those who develop DS-VRE infection post transplantation; however, mortality at 30 days and 6 months is not significantly worse. Further study is needed to determine optimal strategies for the prevention and treatment of DNS-VRE infections in LTRs.
    MeSH term(s) Adult ; Aged ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Daptomycin/pharmacology ; Daptomycin/therapeutic use ; Enterococcus faecium/drug effects ; Female ; Gram-Positive Bacterial Infections/drug therapy ; Gram-Positive Bacterial Infections/epidemiology ; Gram-Positive Bacterial Infections/etiology ; Humans ; Liver/drug effects ; Liver Transplantation/adverse effects ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Vancomycin/pharmacology ; Vancomycin/therapeutic use ; Vancomycin-Resistant Enterococci/drug effects ; Vancomycin-Resistant Enterococci/isolation & purification ; Vancomycin-Resistant Enterococci/physiology
    Chemical Substances Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU) ; Daptomycin (NWQ5N31VKK)
    Language English
    Publishing date 2018-04-16
    Publishing country Denmark
    Document type Comparative Study ; Journal Article
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.12856
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Introduced and native plant species composition of vacant unmanaged green roofs in New York City

    Aloisio, Jason M / Palmer, Matthew I / Tuininga, Amy R / Lewis, J. D

    Urban ecosystems. 2020 Dec., v. 23, no. 6

    2020  

    Abstract: Vacant spaces, such as unplanted, unmanaged, or infrequently accessed green roofs, may play a critical role in sustaining biodiversity in cities. Initial plant composition of these spaces likely is contingent on seed dispersal and growing medium, yet no ... ...

    Abstract Vacant spaces, such as unplanted, unmanaged, or infrequently accessed green roofs, may play a critical role in sustaining biodiversity in cities. Initial plant composition of these spaces likely is contingent on seed dispersal and growing medium, yet no studies have directly characterized the effects of location or growing medium depth on plant diversity of unplanted green roofs. To address this gap, we studied first-year community composition of five unplanted green roofs in New York City (NY, USA). On each roof, 12 plots were established with media depths ranging from 5 to 13 cm. Four months after installation, all plants were harvested. We observed 29 species across locations; five species were found on all five roofs, while 13 species each were observed on a single roof. Introduced species accounted for 14 of the 29 species found across roofs. Species richness and composition differed among roofs, while functional richness varied within, but not among, roofs. About 80% of the variation in species richness was accounted for by total green space in the neighborhoods within 100 to 200 m of each roof. Functional richness and plant cover increased with increased growing medium depth, as did the relative abundance of annual and forb species. Our results suggest both location and growing medium depth will affect initial community composition of unmanaged green roofs, but with differential effects on community assembly. These results also highlight the potential role of unmanaged vacant roofs as reservoirs of plant diversity, both native and invasive, in urban spaces.
    Keywords community structure ; forbs ; indigenous species ; introduced species ; seed dispersal ; species richness ; New York
    Language English
    Dates of publication 2020-12
    Size p. 1227-1238.
    Publishing place Springer US
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2019257-5
    ISSN 1573-1642 ; 1083-8155
    ISSN (online) 1573-1642
    ISSN 1083-8155
    DOI 10.1007/s11252-020-00992-6
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: A Rapid Seedling Resistance Assay Identifies Wild Tomato Lines That Are Resistant to Pseudomonas syringae pv. tomato Race 1.

    Hassan, J A / Zhou, Y J / Lewis, J D

    Molecular plant-microbe interactions : MPMI

    2017  Volume 30, Issue 9, Page(s) 701–709

    Abstract: Bacterial speck caused by Pseudomonas syringae has historically been controlled by the Pto/Prf gene cluster. Emerging strains like P. syringae pv. tomato race 1 overcome resistance conferred by Pto/Prf, and can cause serious crop loss under appropriate ... ...

    Abstract Bacterial speck caused by Pseudomonas syringae has historically been controlled by the Pto/Prf gene cluster. Emerging strains like P. syringae pv. tomato race 1 overcome resistance conferred by Pto/Prf, and can cause serious crop loss under appropriate environmental conditions. We developed a rapid assay to screen wild tomato seedlings for resistance to P. syringae pv. tomato race 1. We established the seedling resistance assay using the well-characterized P. syringae pv. tomato race 0 strain, DC3000, which is recognized in tomato cultivars carrying Pto/Prf (PtoR) and causes disease in isogenic lines lacking this cluster (PtoS). We optimized infectious conditions for P. syringae on tomato seedlings and demonstrated that tomato seedlings respond like adult tomato plants in critical measures of susceptibility and immunity, including the hypersensitive response, rapid ion leakage, restricted bacterial proliferation, and phenotypic resistance. After establishing infectious conditions for P. syringae pv. tomato race 1 on tomato seedlings, we screened 96 wild accessions and identified two accessions with strong P. syringae pv. tomato race 1 resistance, Solanum neorickii LA1329 and S. habrochaites LA1253, which are also resistant to bacterial infection as adult plants. This rapid high throughput seedling assay has many advantages, including reduced plant growth time and large sample sizes, and will allow for large-scale screening of resistance in tomato.
    Language English
    Publishing date 2017-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 743331-1
    ISSN 1943-7706 ; 0894-0282
    ISSN (online) 1943-7706
    ISSN 0894-0282
    DOI 10.1094/MPMI-11-16-0247-R
    Database MEDical Literature Analysis and Retrieval System OnLINE

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