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Article: [Experimental study on the effect of tooth movement with thin and thick aligners in rabbits].

Li, Guang-Hui / Pan, Xiao-Gang

Shanghai kou qiang yi xue = Shanghai journal of stomatology

2021 Volume 30, Issue 1, Page(s) 38–43

Abstract: Purpose: To explore the effect of tooth movement on lower incisors of rabbits with thin and thick aligners.: Methods: A group of 6 male New Zealand rabbits were randomly divided into 2 groups, the experimental group(n=3) was designed to move the ... ...

Abstract	Purpose: To explore the effect of tooth movement on lower incisors of rabbits with thin and thick aligners. Methods: A group of 6 male New Zealand rabbits were randomly divided into 2 groups, the experimental group(n=3) was designed to move the lower incisors distally by 3 steps with thin and thick aligners(0.625 and 0.75 mm)，0.33 mm each；the control group (n=3) was designed to move the teeth by 3 steps with aligner of conventional thickness (0.75 mm), 0.20 mm each. Polyvinyl siloxane impressions were taken before and after aligner placement. The data of tooth movement were measured. SPSS 19.0 software package was used for statistical analysis. Results: The accuracy of tooth movement expression in both groups decreased gradually from the incisal part to the gingival part. The rate of tooth movement in the experimental group was significantly higher than that of the control group（P<0.001）. Conclusions: The tooth movement of rabbit mandibular central incisor was tipping with the clear aligner. The rate of tooth movement was increased by applying thin and thick aligners，but the accuracy of tooth movement was decreased.
MeSH term(s)	Animals ; Incisor ; Male ; Rabbits ; Tooth Movement Techniques
Language	Chinese
Publishing date	2021-04-19
Publishing country	China
Document type	Journal Article
ZDB-ID	2269714-7
ISSN	1006-7248
ISSN	1006-7248
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Article: [Remediation of Cd Contaminated Acidic Rice Fields Using the Combined Application of Lime and Organic Matter].

Li, Guang-Hui / Cheng, Qing / Chen, Hong

Huan jing ke xue= Huanjing kexue

2021 Volume 42, Issue 2, Page(s) 925–931

Abstract: Using an in-situ experiment in Cd contaminated paddy fields in Chongqing, the absorption and distribution of Cd in rice plants was examined following the combined application of lime and organic matter, and the mechanisms driving changes in Cd fractions ... ...

Abstract	Using an in-situ experiment in Cd contaminated paddy fields in Chongqing, the absorption and distribution of Cd in rice plants was examined following the combined application of lime and organic matter, and the mechanisms driving changes in Cd fractions in soil were also studied. The results showed that pH, OM content, and CEC in the soil were significantly enhanced, and OM and CEC were significantly positively correlated, as pH showed a significant positive correlation; pH and CEC was mainly associated with a change in Cd from the acidic extractable fraction to the reducible, oxidable, and residual fractions. The percentage of acidic extractable Cd dropped by 22.92%-31.25% with the application of the amendments, thus reducing the accumulation of Cd in rice plants in the followed order:CK (control group)≫B6 (lime and maize straw)≈B4 (lime and biochar)≈B3 (lime and activated humic acidic fertilizer) > B2 (lime and humic acidic fertilizer)≈B1 (lime) > B5 (lime and oil cake). On the other hand, for both the treatments and control conditions (CK), the Cd content of brown rice was higher than Chinese standard (GB 2762-2017), while that of polished (white) rice was lower than the Chinese standard after treatment. Overall, treatment using all of the remediation agents offers some benefit for the safe utilization of agricultural contaminated soil and safe food production. The combined application of lime and oil cake proved the best measure for treating Cd contaminated acidic rice fields, yielding a reduction in acidic extractable Cd (31.25%), a reduction in the Cd content of rice plants (33.32%), and the lowest Cd content (0.13 mg·kg
Language	Chinese
Publishing date	2021-03-20
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	0250-3301
ISSN	0250-3301
DOI	10.13227/j.hjkx.202007237
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Article ; Online: MicroRNA-16 functions as a tumor-suppressor gene in oral squamous cell carcinoma by targeting AKT3 and BCL2L2.

Wang, Xi / Li, Guang-Hui

Journal of cellular physiology

2018 Volume 233, Issue 12, Page(s) 9447–9457

Abstract: Aberrant expressions of microRNAs have been reported to be strongly associated with the progression and prognosis of various tumors, including oral squamous cell carcinoma (OSCC). Recent studies on miRNA expression profiling have suggested that microRNA- ... ...

Abstract	Aberrant expressions of microRNAs have been reported to be strongly associated with the progression and prognosis of various tumors, including oral squamous cell carcinoma (OSCC). Recent studies on miRNA expression profiling have suggested that microRNA-16 (miR-16) may be dysregulated in OSCC. However, the tumorigenic roles and mechanisms of miR-16 in OSCC are still largely unknown. In this study, we demonstrated that miR-16 was specifically downregulated in both OSCC patients and cancer cell lines. In addition, functional roles of miR-16 in vitro suggested that the miR-16 mimic inhibited cell proliferation and induced apoptosis, whereas miR-16 inhibitor displayed the opposite effects. Luciferase reporter assay and correlation analysis showed that AKT3 and BCL2L2 were directly targeted by miR-16 and were inversely expressed with miR-16 in OSCC. Moreover, restoration of AKT3 and BCL2L2 expression could partially reverse the cell proliferation inhibition and apoptosis induction caused by miR-16. In xenograft nude mice, miR-16 mimics decreased the expression of AKT3 and BCL2L2 and reduced the tumors volumes and weights, whereas the miR-16 inhibitor exhibited adverse effects in the derived xenografts. In conclusion, the findings suggested that miR-16 functions as a tumor suppressor miRNA to inhibit cell proliferation and induce apoptosis in OSCC through decreasing the oncogenes AKT3 and BCL2L2 and that miR-16 could be a potential therapeutic target for OSCC.
MeSH term(s)	3' Untranslated Regions/genetics ; Animals ; Apoptosis/genetics ; Apoptosis Regulatory Proteins/metabolism ; Base Sequence ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Down-Regulation ; Gene Expression Regulation, Neoplastic ; Genes, Tumor Suppressor ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Models, Biological ; Mouth Neoplasms/genetics ; Mouth Neoplasms/pathology ; Proto-Oncogene Proteins c-akt/metabolism ; Xenograft Model Antitumor Assays
Chemical Substances	3' Untranslated Regions ; Apoptosis Regulatory Proteins ; BCL2L2 protein, human ; MIRN16 microRNA, human ; MicroRNAs ; AKT3 protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
Language	English
Publishing date	2018-08-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3116-1
ISSN	1097-4652 ; 0021-9541
ISSN (online)	1097-4652
ISSN	0021-9541
DOI	10.1002/jcp.26833
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Article: Pharmacokinetics of Danofloxacin in Gushi Chickens after Single Oral and Intravenous Administration.

Chen, Jun-Cheng / Yang, Fang / Li, Guang-Hui / Duan, Ming-Hui / Li, Ze-En / Dai, Yan / Zhang, Mei / Yang, Fan

Metabolites

2023 Volume 13, Issue 8

Abstract: This study aimed to determine the pharmacokinetics of danofloxacin in Gushi chickens after a single oral (PO) and intravenous (IV) dose at 5 mg/kg body weight (BW). Thirty-two Gushi chickens, aged 20 weeks, were selected and divided into two groups at ... ...

Abstract	This study aimed to determine the pharmacokinetics of danofloxacin in Gushi chickens after a single oral (PO) and intravenous (IV) dose at 5 mg/kg body weight (BW). Thirty-two Gushi chickens, aged 20 weeks, were selected and divided into two groups at random, with each group consisting of 16 chickens, evenly distributed between males and females. Following danofloxacin administration, blood samples were taken at predetermined time intervals and the plasma was separated. The concentrations of danofloxacin in plasma were quantified by HPLC with a fluorescence detector. Then the concentrations versus time data were subjected to non-compartmental analysis (NCA) using Phoenix software (version: 8.1.0). After administering danofloxacin orally at a dose of 5 mg/kg BW to Gushi chickens, our results demonstrated that the peak concentration reached 0.53 μg/mL at 4 h. The half-life of absorption (t
Language	English
Publishing date	2023-08-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662251-8
ISSN	2218-1989
ISSN	2218-1989
DOI	10.3390/metabo13080906
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Article ; Online: Depletion of tilmicosin residue in Gushi chickens following oral administration via drinking water.

Zhang, Mei / Qian, Kun / Li, Guang-Hui / Duan, Ming-Hui / Li, Ze-En / Dai, Yan / Chen, Jun-Cheng / Yang, Fan

Journal of veterinary pharmacology and therapeutics

2023 Volume 47, Issue 2, Page(s) 114–120

Abstract: This study aimed to examine the depletion of tilmicosin residues in Gushi chickens following the administration at a concentration of 75 mg/L in their drinking water for three consecutive days. Plasma, liver, kidney, lung, muscle, and skin + fat samples ... ...

Abstract	This study aimed to examine the depletion of tilmicosin residues in Gushi chickens following the administration at a concentration of 75 mg/L in their drinking water for three consecutive days. Plasma, liver, kidney, lung, muscle, and skin + fat samples were collected from 6 chickens at 6 h, 1, 3, 5, and 7 days after the treatment. Tilmicosin concentrations in the samples were determined using a high-performance liquid chromatography (HPLC) method. The findings revealed that the highest tilmicosin residues were detected in the liver, followed by the kidney, lung, skin + fat, muscle, and plasma. Notably, at 7 days post-treatment, no drug residue was detected in all samples except for the liver and kidney. The non-compartmental model was employed to calculate relevant pharmacokinetic parameters. The elimination half-lives (t
MeSH term(s)	Animals ; Anti-Bacterial Agents ; Drinking Water ; Chickens ; Administration, Oral ; Tylosin/analogs & derivatives
Chemical Substances	tilmicosin (XL4103X2E3) ; Anti-Bacterial Agents ; Drinking Water ; Tylosin (YEF4JXN031)
Language	English
Publishing date	2023-11-10
Publishing country	England
Document type	Journal Article
ZDB-ID	435216-6
ISSN	1365-2885 ; 0140-7783
ISSN (online)	1365-2885
ISSN	0140-7783
DOI	10.1111/jvp.13416
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Article ; Online: Long non-coding RNA CCAT1 is a prognostic biomarker for the progression of oral squamous cell carcinoma via miR-181a-mediated Wnt/β-catenin signaling pathway.

Li, Guang-Hui / Ma, Zhong-Hui / Wang, Xi

Cell cycle (Georgetown, Tex.)

2019 Volume 18, Issue 21, Page(s) 2902–2913

Abstract: Oral squamous cell carcinoma (OSCC) ranks as the sixth most common carcinoma worldwide, and the third most common carcinoma in developing countries as well. Recently, the aberrant expression of lncRNA CCAT1 has been revealed to play an important role in ... ...

Abstract	Oral squamous cell carcinoma (OSCC) ranks as the sixth most common carcinoma worldwide, and the third most common carcinoma in developing countries as well. Recently, the aberrant expression of lncRNA CCAT1 has been revealed to play an important role in the development of several cancers. However, its role in OSCC remains unknown. The expression levels of CCAT1 and miR-181a were determined in 15 paired primary OSCC tissues and their adjacent noncancerous tissues and cell lines with qPCR. shRNA against CCAT1 was employed to investigate the impact of CCAT1 on proliferation and metastasis. Then dual luciferase reporter and RIP assays were utilized to study the interaction between CCAT1 and miR-181a. Cells transfected with sh-CCAT1 or treated with miR-181a inhibitor were subjected to western blot to investigate the role of Wnt/β-catenin signaling in CCAT1-mediated proliferation and metastasis. Finally, the role of CCAT1 in OSCC was confirmed with tumor xenografts mice model. CCAT1 was upregulated in OSCC tissues and cell lines. Knockdown of CCAT1 inhibited the proliferation, migration and invasion of OSCC cells, while the cell apoptosis was enhanced. Luciferase and RIP assays revealed that miR-181a was a direct target of CCAT1. Inhibition of miR-181a partially reversed the efficacy of sh-CCAT1. Moreover, sh-CCAT1 inhibited OSCC tissues growth through inhibiting Wnt signaling in a miR-181a-dependent manner
MeSH term(s)	Animals ; Apoptosis/genetics ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; Mouth Neoplasms/genetics ; Mouth Neoplasms/pathology ; Neoplasm Metastasis/genetics ; Neoplasm Transplantation ; RNA Interference ; RNA, Long Noncoding/genetics ; RNA, Small Interfering/genetics ; Transplantation, Heterologous ; Wnt Proteins/metabolism ; Wnt Signaling Pathway/genetics ; beta Catenin/metabolism
Chemical Substances	CCAT1 long noncoding RNA, human ; MIrn181 microRNA, human ; MicroRNAs ; RNA, Long Noncoding ; RNA, Small Interfering ; Wnt Proteins ; beta Catenin
Language	English
Publishing date	2019-09-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2146183-1
ISSN	1551-4005 ; 1538-4101 ; 1554-8627
ISSN (online)	1551-4005
ISSN	1538-4101 ; 1554-8627
DOI	10.1080/15384101.2019.1662257
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Article ; Online: Outlier Detection in Wireless Sensor Networks Using Model Selection-Based Support Vector Data Descriptions.

Huan, Zhan / Wei, Chang / Li, Guang-Hui

Sensors (Basel, Switzerland)

2018 Volume 18, Issue 12

Abstract: Wireless sensor networks (WSNs) are often deployed in harsh and unattended environments, which may cause the generation of abnormal or low quality data. The inaccurate and unreliable sensor data may increase generation of false alarms and erroneous ... ...

Abstract	Wireless sensor networks (WSNs) are often deployed in harsh and unattended environments, which may cause the generation of abnormal or low quality data. The inaccurate and unreliable sensor data may increase generation of false alarms and erroneous decisions, so it's very important to detect outliers in sensor data efficiently and accurately to ensure sound scientific decision-making. In this paper, an outlier detection algorithm (TSVDD) using model selection-based support vector data description (SVDD) is proposed. Firstly, the Toeplitz matrix random feature mapping is used to reduce the time and space complexity of outlier detection. Secondly, a novel model selection strategy is realized to keep the algorithm stable under the low feature dimensions, this strategy can select a relatively optimal decision model and avoid both under-fitting and overfitting phenomena. The simulation results on SensorScope and IBRL datasets demonstrate that, TSVDD achieves higher accuracy and lower time complexity for outlier detection in WSNs compared with existing methods.
Language	English
Publishing date	2018-12-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s18124328
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Article ; Online: Influencing Factors of Eco-Environmental Safety of Mines and Their Green Development

Wei Xiao Gang, Liu Hui Li , Li Guang Hui

Nature Environment and Pollution Technology, Vol 19, Iss 2, Pp 831-

A Case Study of Taoshan Coal Mine in Heilongjiang Province, China

2020 Volume 838

Abstract: The demand for mineral resources is continuously increasing due to the accelerated industrialization and urbanization progress. However, most mines in China have backward mining technology, enormous destruction and waste, too low recycling proportion, ... ...

Abstract	The demand for mineral resources is continuously increasing due to the accelerated industrialization and urbanization progress. However, most mines in China have backward mining technology, enormous destruction and waste, too low recycling proportion, unstable mineral market, and low management efficiency. Thus, the eco-environmental safety of mines has various difficulties. Identifying the influencing factors of eco-environmental safety of mines, which are typical ecologically vulnerable areas, is important. The green development of mines is a clean production mode that will not generate any harmful effect on human social and natural environments and will be important to realizing sustainable development of mines. In this study, a retrospective analysis of considerable foreign literature on ecoenvironmental safety management of mines in developed countries was conducted. An index system of the influencing factors of eco-environmental safety of Taoshan Coal Mine in Heilongjiang Province, China was established. ISM model (Interpretative Structural Modeling) was used to analyze the influencing factors of eco-environmental safety, and corresponding countermeasures for critical factors were proposed. Results indicate that studies on resource development and utilization and environmental protection of mines in some developed countries, such as America, Australia, and the UK, have been considerably mature. The influencing factors in ISM (Interpretative Structural Modeling) can be divided into three layers, among which the completeness of institution setting for environmental protection supervision is a factor with the most significant influence on mine eco-environmental safety. Input into eco-environmental protection and ecological protection laws and systems of mines are also important factors. The study results are important in determining the most critical influencing factors of mine eco-environmental safety, innovating the new industrial development pattern featured by conservation and intensive and comprehensive ...
Keywords	Environmental effects of industries and plants ; TD194-195 ; Science (General) ; Q1-390
Subject code	690
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	Technoscience Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Vulnerability Measurement of Groundwater Inrush Channel in Mining Areas and Environmental Governance Measures – A Case Study on Taoshan Mine, China

Wei Xiao Gang, Dai Jun Wu, Li Guang Hui, Hu Zhi Kai and Qin Sai

Nature Environment and Pollution Technology, Vol 20, Iss 2, Pp 785-

2021 Volume 791

Abstract: The unrestricted resource behaviour of mines has caused considerable geological environmental problems. Specifically, the increasing water-induced accidents in mines affect safety production and environmental safety in coal mines. To further decrease ... ...

Abstract	The unrestricted resource behaviour of mines has caused considerable geological environmental problems. Specifically, the increasing water-induced accidents in mines affect safety production and environmental safety in coal mines. To further decrease water inrush disasters to the maximum extent, vulnerability assessment of groundwater inrush channel in coal mines has become a primary problem of chain-cutting disaster mitigation. In this study, first, influencing factors against formation and project of water inrush channel in coals were analyzed comprehensively. Second, 14 indexes, which influence the vulnerability of the water inrush channel, were selected from three perspectives of coal seam features, coal quality features, and hydrogeological features. A case study based on data of 56# coal seam and 68 coal seam of Taoshan Mine, China was carried out. The vulnerability of the groundwater inrush channel in the Taoshan Mine was estimated by analytic hierarchy process (AHP) and fuzzy comprehensive evaluation. Results demonstrate that coal quality features, hydrogeological features, and coal seam features are major factors that influence the vulnerability of the water inrush channel. Among them, coal quality features contribute 48.36% of explanations to the vulnerability of the water inrush channel. According to the vulnerability grade evaluation results of fuzzy mathematics, the membership degree of belonging to “III” was 0.3731, which was the highest. This finding indicates that the vulnerability of the water inrush channel in Taoshan Mine belongs to grade III, which is a moderate state. Research conclusions have important references to perfect the evaluation index system for the vulnerability of water inrush channel in coal mines, provide early warning analysis of water inrush disasters in coal mines, and realize the mining–environmental protection coordinated development.
Keywords	underground coal mines ; water inrush channel ; vulnerability measurement ; environmental governance ; taoshan mine ; Environmental effects of industries and plants ; TD194-195 ; Science (General) ; Q1-390
Subject code	550
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	Technoscience Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Interactions between 7S/11S soybean globulins and wheat proteins during dough making

Gao, Xue-Li / Chen, Fu-Sheng / Wang, Yong-Hui / He, Sheng-Hua / Guo, Wei-Yun / Li, Guang-Hui

Journal of food measurement & characterization. 2021 Dec., v. 15, no. 6

2021

Abstract: Attributing the nutritional effect of soybean protein, supplementation of wheat flour with soy flour has gained more and more attentions. The interactions between soybean protein and wheat gluten were believed to influences the dough making properties of ...

Abstract	Attributing the nutritional effect of soybean protein, supplementation of wheat flour with soy flour has gained more and more attentions. The interactions between soybean protein and wheat gluten were believed to influences the dough making properties of wheat flour. Interactions between glycinin/β-conglycinin (11S/7S) and wheat proteins during dough making were explored in this study. Size exclusion-high-performance liquid chromatography (SE-HPLC) and electrophoresis were used to characterize these interactions. The results showed that 7S/11S interacted with wheat proteins during dough making, forming high molecular weight polymers. Addition of 11S (3% or 4%) resulted in a higher percentage of unextractable polymeric proteins (UPP) in total polymeric proteins (34% or 30% UPP) than addition of 7S (26% or 24% UPP) at the same conditions. Electrophoresis showed that the interactions between 11S and wheat protein were disulfide bonds and that the interactions for 7S and wheat protein were non-covalent bonds.
Keywords	disulfides ; dough ; electrophoresis ; measurement ; molecular weight ; polymers ; soy flour ; soy protein ; soybeans ; wheat ; wheat flour ; wheat gluten ; wheat protein
Language	English
Dates of publication	2021-12
Size	p. 4939-4945.
Publishing place	Springer US
Document type	Article
ZDB-ID	2754612-3
ISSN	2193-4134 ; 2193-4126
ISSN (online)	2193-4134
ISSN	2193-4126
DOI	10.1007/s11694-021-01069-4
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