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  1. Book ; Online ; Thesis: The influence of R2R3-MYB transcription factors in Campanula medium and Petunia hybrida

    Li, Guo [Verfasser]

    2023  

    Author's details Guo Li
    Keywords Pflanzen (Botanik) ; Plants (Botany)
    Subject code sg580
    Language English
    Publisher Gottfried Wilhelm Leibniz Universität
    Publishing place Hannover
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Article ; Online: Natural nematicidal metabolites and advances in their biocontrol capacity on plant parasitic nematodes.

    Li, Guo-Hong / Zhang, Ke-Qin

    Natural product reports

    2023  Volume 40, Issue 3, Page(s) 646–675

    Abstract: Covering: 2010 to 2021Natural nematicidal metabolites are important sources of nematode control. This review covers the isolation and structural determination of nematicidal metabolites from 2010 to 2021. We summarise chemical structures, bioactivity, ... ...

    Abstract Covering: 2010 to 2021Natural nematicidal metabolites are important sources of nematode control. This review covers the isolation and structural determination of nematicidal metabolites from 2010 to 2021. We summarise chemical structures, bioactivity, metabolic regulation and biosynthesis of potential nematocides, and structure-activity relationship and application potentiality of natural metabolites in plant parasitic nematodes' biocontrol. In doing so, we aim to provide a comprehensive overview of the potential roles that natural metabolites can play in anti-nematode strategies.
    MeSH term(s) Animals ; Antinematodal Agents/pharmacology ; Antinematodal Agents/metabolism ; Nematoda ; Plants/metabolism
    Chemical Substances Antinematodal Agents
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d2np00074a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Improving Report of the ADAURA Trial by Distinguishing Treatment-Related Adverse Events From Treatment-Emergent Adverse Events and Assessing Independence of Censoring in Final Disease-Free Survival Analyses.

    Wu, Danna / Li, Guo-Fu

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 41, Issue 26, Page(s) 4317–4318

    MeSH term(s) Humans ; Disease-Free Survival ; Clinical Trials as Topic
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.00604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1847: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 650: Show issues

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  4. Article ; Online: DNA mismatch repair in cancer immunotherapy.

    Guan, Junhong / Li, Guo-Min

    NAR cancer

    2023  Volume 5, Issue 3, Page(s) zcad031

    Abstract: Tumors defective in DNA mismatch repair (dMMR) exhibit microsatellite instability (MSI). Currently, patients with dMMR tumors are benefitted from anti-PD-1/PDL1-based immune checkpoint inhibitor (ICI) therapy. Over the past several years, great progress ... ...

    Abstract Tumors defective in DNA mismatch repair (dMMR) exhibit microsatellite instability (MSI). Currently, patients with dMMR tumors are benefitted from anti-PD-1/PDL1-based immune checkpoint inhibitor (ICI) therapy. Over the past several years, great progress has been made in understanding the mechanisms by which dMMR tumors respond to ICI, including the identification of mutator phenotype-generated neoantigens, cytosolic DNA-mediated activation of the cGAS-STING pathway, type-I interferon signaling and high tumor-infiltration of lymphocytes in dMMR tumors. Although ICI therapy shows great clinical benefits, ∼50% of dMMR tumors are eventually not responsive. Here we review the discovery, development and molecular basis of dMMR-mediated immunotherapy, as well as tumor resistant problems and potential therapeutic interventions to overcome the resistance.
    Language English
    Publishing date 2023-06-13
    Publishing country England
    Document type Journal Article
    ISSN 2632-8674
    ISSN (online) 2632-8674
    DOI 10.1093/narcan/zcad031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Letter to the Editor Regarding "Clinical Utility of Routine Postprocedural Computed Tomography of the Head Following Elective Neuroendovascular Interventions".

    Li, Guo / Hu, Qin

    World neurosurgery

    2023  Volume 173, Page(s) 299

    MeSH term(s) Humans ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.02.069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Drug-induced Liver Injury With Ritonavir-Boosted Nirmatrelvir: Evidence From Coronavirus Disease 2019 Emergency Use Authorization Adverse Event Reporting System.

    Li, Guo-Fu / Yu, Guo

    Gastroenterology

    2023  Volume 165, Issue 1, Page(s) 305–306

    MeSH term(s) Humans ; Ritonavir/adverse effects ; COVID-19 ; COVID-19 Drug Treatment ; Chemical and Drug Induced Liver Injury/diagnosis ; Chemical and Drug Induced Liver Injury/epidemiology ; Chemical and Drug Induced Liver Injury/etiology ; Antiviral Agents/adverse effects
    Chemical Substances nirmatrelvir (7R9A5P7H32) ; Ritonavir (O3J8G9O825) ; Antiviral Agents
    Language English
    Publishing date 2023-02-18
    Publishing country United States
    Document type Letter
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2023.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.44: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 572: Show issues

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  7. Article ; Online: A systematic review and meta-analysis for platelet-rich plasma in treatment of knee osteoarthritis

    Rong Xie / Li-Guo Zhu

    Journal of Hainan Medical University, Vol 28, Iss 4, Pp 29-

    2022  Volume 36

    Abstract: Objective: To systematically evaluate the efficacy and safety of platelet-rich plasma in patients with knee osteoarthritis. Methods: The Pubmed, Cochrane Library, Embase,and Medline were investigated from 2005 through May 2020.All randomized double-blind ...

    Abstract Objective: To systematically evaluate the efficacy and safety of platelet-rich plasma in patients with knee osteoarthritis. Methods: The Pubmed, Cochrane Library, Embase,and Medline were investigated from 2005 through May 2020.All randomized double-blind controlled trials were included the effect of PRP injections for KOA. Literature screening and data extraction were carried out independently by two researchers, and the quality of the included randomized controlled trials was evaluated one by one according to the Cochrane collaboration standards. Meta-statistical analysis was performed for the studies that met the inclusion standards using RevMan5.3. Results: In this study,(1)Seven studies met the eligibility criteria, including 250 patients in the experiment (PRP)group and 230patients in the control(no PRP)group.(2)Metaanalysis results showed that the WOMAC Scores was differed significantly between the PRP and no PRP groups at the 6 months follow-up(MD=9.63,95%CI:3.29 to 15.96,P=0.003),and 12 months follow-up(MD=3.85,95%CI:2.66 to 5.04,P<0.00001)(P<0.05).In a comparison of KOOS function scores at the 6 months follow-up, PRP improved knee function scores more than no PRP(MD=8.63,95%CI:0.85 to 16.42,P=0.03) (P<0.05).PRP injections reduced pain more effectively than no PRP injections in patients with KOA at 3,6 months of follow-up, and the VAS pain score showed a significant difference(SMD=0.88,95%CI:0.13 to 1.62,P=0.02) (SMD=0.85,95%CI:0.11 to 1.59,P=0.002)(P<0.05). However, Adverse Events (AEs) were all not significantly different(RR=0.96,95%CI:0.65 to 1.40,P=0.82)(P>0.05).(3)Results showed that PRP has significant advantages in pain relief and functional improvement. Conclusions: In improving knee function and relieving pain, PRP showed superiority to other non-surgical treatments in long-term follow-up from well-designed double-blind trials. Due to the limited quality and data, more high-quality multi-center studies are required.
    Keywords platelet-rich plasma ; knee osteoarthritis ; pain ; function ; double-blind controlled trials ; systematic review ; meta-analysis ; Medicine ; R
    Subject code 630
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The reconstruction on the game networks with binary-state and multi-state dynamics.

    Junfang Wang / Jin-Li Guo

    PLoS ONE, Vol 17, Iss 2, p e

    2022  Volume 0263939

    Abstract: Reconstruction of network is to infer the relationship among nodes using observation data, which is helpful to reveal properties and functions of complex systems. In view of the low reconstruction accuracy based on small data and the subjectivity of ... ...

    Abstract Reconstruction of network is to infer the relationship among nodes using observation data, which is helpful to reveal properties and functions of complex systems. In view of the low reconstruction accuracy based on small data and the subjectivity of threshold to infer adjacency matrix, the paper proposes two models: the quadratic compressive sensing (QCS) and integer compressive sensing (ICS). Then a combined method (CCS) is given based on QCS and ICS, which can be used on binary-state and multi-state dynamics. It is found that CCS is usually a superior method comparing with compressive sensing, LASSO on several networks with different structures and scales. And it can infer larger node correctly than the other two methods. The paper is conducive to reveal the hidden relationship with small data so that to understand, predicate and control a vast intricate system.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Research on quantitative evaluation of digital economy policy in China based on the PMC index model.

    Hong, Shuai / Wang, Tianzun / Fu, Xiaoyi / Li, Guo

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0298312

    Abstract: The development of digital economy is a strategic choice to grasp the revolution of new science and technology and the new opportunities of industrial reform. The development of digital economy depends on the good support of policy and theoretical system. ...

    Abstract The development of digital economy is a strategic choice to grasp the revolution of new science and technology and the new opportunities of industrial reform. The development of digital economy depends on the good support of policy and theoretical system. Therefore, the quantitative evaluation of policy texts provides the basis of decision-making and the suggestions of path optimization for the formulation and improvement of digital economy policy of China. By selecting the text of digital economy policy issued by China government, the paper constructs a quantitative evaluation model of digital economy policy using the methods of content analysis and text mining. The empirical research results show that the overall design evaluation of the selected policy is relatively reasonable. Six policies were evaluated as excellent and two as acceptable. In view of the problems such as lack of predictive policy in the policy type, lack of specific policy in the policy timeliness, imbalance in the use of policy guarantee, and lack of comprehensive coverage in the policy objectives, the paper puts forward corresponding countermeasures and suggestions.
    MeSH term(s) China ; Data Mining ; Government ; Industry ; Policy ; Economic Development
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Strategic significance of constructing a Chinese medicine prevention and control system for the implementation of the bone health program].

    Zhu, Li-Guo / Wei, Xu / Zhang, Yi-Li

    Zhongguo gu shang = China journal of orthopaedics and traumatology

    2024  Volume 37, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Medicine, Chinese Traditional ; Bone Density ; Drugs, Chinese Herbal ; China
    Chemical Substances Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2024-01-29
    Publishing country China
    Document type Journal Article
    ISSN 1003-0034
    ISSN 1003-0034
    DOI 10.12200/j.issn.1003-0034.20240068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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