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  1. Article: [Design and application of a warming fixation device for premature infants].

    Li, Huixian

    Zhonghua wei zhong bing ji jiu yi xue

    2024  Volume 36, Issue 2, Page(s) 205–207

    Abstract: Objective: A warming fixation device for premature infants was made and its clinical application effect was discussed.: Methods: The warming fixation device for premature infants was designed and used in clinic. Sixty premature infants admitted to ... ...

    Abstract Objective: A warming fixation device for premature infants was made and its clinical application effect was discussed.
    Methods: The warming fixation device for premature infants was designed and used in clinic. Sixty premature infants admitted to the neonatal ward of Baoding Hospital, Beijing Children's Hospital, Capital Medical University from January to June 2022 were selected as the control group, and 60 premature infants admitted from July to December 2022 were selected as the experimental group. In the control group, umbilical vein catheterization or central vein catheterization were performed using Astro Boy heating box, restraint band or artificial restraint. The preterm infants in the experimental group were radiated into the Astro Boy warm box with self-designed preterm warming fixation device for catheterization. The time of catheterization, the number of limb protrusion, the number of participants in catheterization operation, and the body temperature from 20 minutes of catheterization operation to the end of catheterization operation were recorded in the two groups. The frequency of hypothermia (< 36.5 centigrade) was calculated, and the differences in various indexes between the two groups were compared.
    Results: (1) The warming fixation device for premature babies consists of two parts: warm sleeping bag and soft pad. The warm sleeping bag includes 4 parts: head, arm, chest and abdomen, and lower limbs. The chest and abdomen were designed with rectangular covering cloth, which can be opened to facilitate umbilical vein puncture for premature infants. There were 3 groups of restraint belts on the rectangular soft pad, which can respectively fix the arms, chest and abdomen of the warm sleeping bag and the lower limbs. During the catheterization operation, use Velcro to secure the warm sleeping bag to the cushioned surface, and select the area of exposed skin according to the piercing site. (2) There were no significant differences in gender, body weight and gestational age between the experimental group and the control group [male: 48.3% vs. 46.7%, body weight (kg): 1.86±0.06 vs. 1.82±0.06, gestational age (weeks): 31.33±0.31 vs. 32.25±0.34, all P > 0.05]. Compared with the control group, the catheterization time of experimental group was significantly shortened (minutes: 21.30±0.43 vs. 30.02±0.64, P < 0.01), the number of limb protrusion was significantly reduced (0 time: 70.0% vs. 33.3%, 1 time: 26.7% vs. 50.0%, P < 0.01), and the number of participants in catheterization operation was significantly reduced (people: 1.77±0.06 vs. 2.37±0.06, P < 0.01). The frequency of hypothermia in experimental group was significantly lower than that in the control group [6.12% (6/98) vs. 26.50% (31/117), χ2 = 15.536, P < 0.01].
    Conclusions: The warming fixation device for premature infants is convenient to use, which can effectively shorten the tube placement time, save human resources, and reduce the incidence of hypothermia in premature infants.
    MeSH term(s) Infant, Newborn ; Infant ; Child ; Humans ; Male ; Infant, Premature ; Hypothermia ; Gestational Age ; Body Temperature ; Body Weight
    Language Chinese
    Publishing date 2024-03-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 2095-4352
    ISSN 2095-4352
    DOI 10.3760/cma.j.cn121430-20230505-00332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Dialectical Thinking Is Linked With Smaller Left Nucleus Accumbens and Right Amygdala.

    Li, Hui-Xian / Hu, Xiaomeng

    Frontiers in psychology

    2022  Volume 13, Page(s) 760489

    Abstract: Our current work examined the interface between thinking style and emotional experience at both the behavioral and neuropsychological levels. Thirty-nine Chinese participants completed the triad task, and we calculated the rate of individually selected ... ...

    Abstract Our current work examined the interface between thinking style and emotional experience at both the behavioral and neuropsychological levels. Thirty-nine Chinese participants completed the triad task, and we calculated the rate of individually selected relationship pairings to overall selections to represent their holistic thinking tendencies. In addition, participants in the top one-third of the ratio score were classified into the high holistic thinking group, while those in the bottom one-third of the ratio score were classified into the low holistic thinking group. We used the sensitivity to punishment and sensitivity to reward questionnaire (SPSRQ) to examine how people elicit positive and negative affective behaviors. Additionally, we examined the volume of the amygdala and nucleus accumbens and their functional connectivity in the resting-state. We found that high holistic thinkers were much less sensitive to rewards than low holistic thinkers. In other words, individuals with high holistic thinking are less likely to pursue behaviors that have positive emotional outcomes. Furthermore, their bilateral nucleus accumbens and right amygdala volumes were smaller than those of low holistic thinkers. Hierarchical regression analysis showed that holistic thinking tendency can negatively predict the volume of the left nucleus accumbens and right amygdala. Finally, resting-state functional connectivity results showed increased functional connectivity FC between left nucleus accumbens and bilateral amygdala in high holistic thinkers. These findings provide emotion-related manifestations of thinking styles at the behavioral and neural levels.
    Language English
    Publishing date 2022-02-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.760489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Amiodarone Advances the Apoptosis of Cardiomyocytes by Repressing Sigmar1 Expression and Blocking KCNH2-related Potassium Channels.

    Liang, Huiqing / Li, Huixian / Li, Fangjiang / Xiong, Xiaobo / Gao, Yang

    Current molecular medicine

    2024  

    Abstract: Background: Heart failure (HF) is the ultimate transformation result of various cardiovascular diseases. Mitochondria-mediated cardiomyocyte apoptosis has been uncovered to be associated with this disorder.: Objective: This study mainly delves into ... ...

    Abstract Background: Heart failure (HF) is the ultimate transformation result of various cardiovascular diseases. Mitochondria-mediated cardiomyocyte apoptosis has been uncovered to be associated with this disorder.
    Objective: This study mainly delves into the mechanism of the anti-arrhythmic drug amiodarone on mitochondrial toxicity of cardiomyocytes.
    Methods: The viability of H9c2 cells treated with amiodarone at 0.5, 1, 2, 3, and 4 μM was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and Sigmar1 expression was examined by quantitative real-time PCR (qRTPCR). After transfection, the viability, apoptosis, reactive oxygen species (ROS) level, mitochondrial membrane potential (MMP), and potassium voltage-gated channel subfamily H member 2 (KCNH2) expression in H9c2 cells were assessed by MTT, flow cytometry, ROS assay kit, mitochondria staining kit, and Western blot.
    Results: Amiodarone at 1-4 μM notably weakened H9c2 cell viability with IC50 value of 2.62 ± 0.43 μM. Amiodarone at 0.5-4 μM also evidently suppressed the Sigmar1 level in H9c2 cells. Amiodarone repressed H9c2 cell viability and KCNH2 level and triggered apoptosis, ROS production and mitochondrial depolarization, while Sigmar1 upregulation reversed its effects. Moreover, KCNH2 silencing neutralized the combined modulation of amiodarone and Sigmar1 up-regulation on H9c2 cell viability, apoptosis, and ROS production.
    Conclusion: Amiodarone facilitates the apoptosis of H9c2 cells by restraining Sigmar1 expression and blocking KCNH2-related potassium channels.
    Language English
    Publishing date 2024-01-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2064873-X
    ISSN 1875-5666 ; 1566-5240
    ISSN (online) 1875-5666
    ISSN 1566-5240
    DOI 10.2174/0115665240265771231129105108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Verrucous Granular Parakeratosis on the Groin: A Case Report.

    Li, Huixian / Li, Hui / Tian, Qinghua / Fang, Xiangang

    Clinical, cosmetic and investigational dermatology

    2023  Volume 16, Page(s) 853–857

    Abstract: Granular parakeratosis is a rare dermatosis characterized by erythematous scaly patches or papules, and plaques, often involving intertriginous areas. In this work, a 73-year-old Chinese male patient presented with a 6-month history of pruritic verrucous ...

    Abstract Granular parakeratosis is a rare dermatosis characterized by erythematous scaly patches or papules, and plaques, often involving intertriginous areas. In this work, a 73-year-old Chinese male patient presented with a 6-month history of pruritic verrucous papules on the bilateral groin. A skin biopsy was performed and revealed the following: the horny layer showed highly compact hyperkeratosis and parakeratosis with basophilic granules; the epidermis showed obvious acanthosis with psoriasiform hyperplasia. The final diagnosis was verrucous granular parakeratosis. We also reviewed the progress in nomenclature, etiology, clinical manifestations, differential diagnosis and treatment. Different clinical manifestations may represent different clinical entities. Dermatologists should differentiate it from other diseases to make a correct diagnosis. Treatment options should be based on the variable etiologies and clinical manifestations.
    Language English
    Publishing date 2023-04-01
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S401799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Toxicity of antimony to Daphnia magna: Influence of environmental factors, development of biotic ligand approach and biochemical response at environmental relevant concentrations.

    Li, Yue / Li, Huixian / Zhang, Ruiqing / Bing, Xiaojie

    Journal of hazardous materials

    2023  Volume 462, Page(s) 132738

    Abstract: Acute toxicity of antimony pentavalent to neonatal Daphnia magna and the influence of water quality parameters were investigated, and enzymatic activities of organisms at environmentally relevant levels of antimony were determined. ... ...

    Abstract Acute toxicity of antimony pentavalent to neonatal Daphnia magna and the influence of water quality parameters were investigated, and enzymatic activities of organisms at environmentally relevant levels of antimony were determined. EC
    MeSH term(s) Animals ; Models, Biological ; Daphnia ; Antimony/toxicity ; Ligands ; Cations/pharmacology ; Water Pollutants, Chemical/toxicity
    Chemical Substances Antimony (9IT35J3UV3) ; Ligands ; Cations ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-10-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.132738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Up-regulation of GPR139 in the medial septum ameliorates cognitive impairment in two mouse models of Alzheimer's disease.

    Mu, Ronghao / Hou, Xiaoying / Liu, Qi / Wang, Wan / Qin, Chi / Li, Huixian

    International immunopharmacology

    2024  Volume 130, Page(s) 111786

    Abstract: G-protein coupled receptors (GPCRs) constitute the largest class of cell surface receptors and present prominent drug targets. GPR139 is an orphan GPCR detected in the septum of the brain. However, its roles in cognition are still unclear. Here we first ... ...

    Abstract G-protein coupled receptors (GPCRs) constitute the largest class of cell surface receptors and present prominent drug targets. GPR139 is an orphan GPCR detected in the septum of the brain. However, its roles in cognition are still unclear. Here we first established a mouse model of cognitive impairment by a single intracerebroventricular injection of aggregated amyloid-beta peptide 1-42 (Aβ
    MeSH term(s) Animals ; Mice ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Cognitive Dysfunction/metabolism ; Disease Models, Animal ; Hippocampus/metabolism ; Mice, Transgenic ; Up-Regulation ; Nerve Tissue Proteins/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Septum of Brain/metabolism ; Mice, Inbred C57BL
    Chemical Substances Amyloid beta-Peptides ; Gpr139 protein, mouse ; Nerve Tissue Proteins ; Receptors, G-Protein-Coupled
    Language English
    Publishing date 2024-03-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2024.111786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Acute toxicity of cerium to neonatal Daphnia magna: Responses of antioxidant systems, influence of environmental factors and development of a biotic ligand model.

    Zhang, Kaibo / Zhang, Ruiqing / Liu, Shuai / Li, Yue / Guo, Guanghui / Li, Huixian / Shao, Shuai

    The Science of the total environment

    2024  Volume 917, Page(s) 170441

    Abstract: The bioavailability of cerium (Ce) and its toxic effects on aquatic organisms are still unclear, which limits the toxicity prediction and pollution control for this element. Here, the acute toxicity of Ce to Daphnia magna neonates and the responses of ... ...

    Abstract The bioavailability of cerium (Ce) and its toxic effects on aquatic organisms are still unclear, which limits the toxicity prediction and pollution control for this element. Here, the acute toxicity of Ce to Daphnia magna neonates and the responses of the antioxidant system were investigated, and the quantitative relationships between the toxicity of Ce and environmental factors were determined. The 24 and 48 h EC50
    MeSH term(s) Animals ; Daphnia magna ; Antioxidants/metabolism ; Cerium/metabolism ; Ligands ; Hydrogen Peroxide/pharmacology ; Daphnia ; Sodium/chemistry ; Water Pollutants, Chemical/metabolism
    Chemical Substances Antioxidants ; Cerium (30K4522N6T) ; Ligands ; Hydrogen Peroxide (BBX060AN9V) ; Sodium (9NEZ333N27) ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-01-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.170441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of tire-road wear particles on the adsorption of tetracycline by aquatic sediments.

    Fan, Xiulei / Cao, Binwen / Wang, Shenpeng / Li, Huixian / Zhu, Mingxian / Sha, Haidi / Yang, Yangyang

    Environmental science and pollution research international

    2024  Volume 31, Issue 20, Page(s) 29232–29245

    Abstract: Tire-road wear particles (TRWPs) are formed by friction between the tire and the road. TRWPs are ubiquitous across the globe, especially in sediments. However, the possible effects of TRWPs on tetracycline (TC) in aquatic sediments are unknown. To ... ...

    Abstract Tire-road wear particles (TRWPs) are formed by friction between the tire and the road. TRWPs are ubiquitous across the globe, especially in sediments. However, the possible effects of TRWPs on tetracycline (TC) in aquatic sediments are unknown. To investigate the potential role of TRWPs as carriers of co-pollutants, this study investigated the pore surface properties and TC adsorption behavior of TRWP-contaminated sediments and explored the TC behavior in water sediments, as well as the role of aging processes and TRWPs abundance. The results showed that the surface morphology of TRWP-contaminated sediments changed and the adsorption capacity of sediments to TC increased. The TC adsorption capacity of sediments contaminated by 2% TRWPs increased from 3.15 to 3.48 mg/g. Moreover, the surface physical and chemical properties of TRWPs after UV aging changed, which further increased the TC adsorption capacity. The TC adsorption capacity of the sediments contaminated by aged TRWPs increased from 3.48 to 3.65 mg/g. Changing the proportion of aged TRWPs, we found that the adsorption capacity of sediments contaminated by different proportions of TRWPs for TC was 2% > 1% > 0.5% > 4% > blank sediment. These results may contribute to predicting the potential environmental risks of TRWPs in aquatic sediments.
    MeSH term(s) Adsorption ; Tetracycline/chemistry ; Geologic Sediments/chemistry ; Water Pollutants, Chemical/chemistry
    Chemical Substances Tetracycline (F8VB5M810T) ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-04-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-33132-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Mapping the neural mechanism that distinguishes between holistic thinking and analytic thinking.

    Teng, Yue / Li, Hui-Xian / Chen, Sylvia Xiaohua / Castellanos, Francisco Xavier / Yan, Chao-Gan / Hu, Xiaomeng

    NeuroImage

    2024  Volume 294, Page(s) 120627

    Abstract: Holistic and analytic thinking are two distinct modes of thinking used to interpret the world with relative preferences varying across cultures. While most research on these thinking styles has focused on behavioral and cognitive aspects, a few studies ... ...

    Abstract Holistic and analytic thinking are two distinct modes of thinking used to interpret the world with relative preferences varying across cultures. While most research on these thinking styles has focused on behavioral and cognitive aspects, a few studies have utilized functional magnetic resonance imaging (fMRI) to explore the correlations between brain metrics and self-reported scale scores. Other fMRI studies used single holistic and analytic thinking tasks. As a single task may involve processing in spurious low-level regions, we used two different holistic and analytic thinking tasks, namely the frame-line task and the triad task, to seek convergent brain regions to distinguish holistic and analytic thinking using multivariate pattern analysis (MVPA). Results showed that brain regions fundamental to distinguish holistic and analytic thinking include the bilateral frontal lobes, bilateral parietal lobes, bilateral precentral and postcentral gyrus, bilateral supplementary motor areas, bilateral fusiform, bilateral insula, bilateral angular gyrus, left cuneus, and precuneus, left olfactory cortex, cingulate gyrus, right caudate and putamen. Our study maps brain regions that distinguish between holistic and analytic thinking and provides a new approach to explore the neural representation of cultural constructs. We provide initial evidence connecting culture-related brain regions with language function to explain the origins of cultural differences in cognitive styles.
    Language English
    Publishing date 2024-05-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1147767-2
    ISSN 1095-9572 ; 1053-8119
    ISSN (online) 1095-9572
    ISSN 1053-8119
    DOI 10.1016/j.neuroimage.2024.120627
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Heat treatment induces chemical changes and silica sol penetration in wood for properties improvement: hydrophobicity, thermal stability, and surface hardness

    Jiang, Jun / Li, Huixian / Pang, Jinhui / Mei, Changtong

    Journal of wood chemistry and technology. 2022 Mar. 1, v. 42, no. 2

    2022  

    Abstract: Thermal modification could act as pretreatment for promoting silica sol impregnation in wood. It could create extra available channels and spaces for silica transportation and deposition owing to the presence of micro-cracks and enlarged pore size. The ... ...

    Abstract Thermal modification could act as pretreatment for promoting silica sol impregnation in wood. It could create extra available channels and spaces for silica transportation and deposition owing to the presence of micro-cracks and enlarged pore size. The significant improvements on anti-hygroscopicity, hydrophobicity, and dimensional stability of treated wood were attributed to the degradation of cell wall polymer (hemicellulose, cellulose, and lignin) and filling effect of silica in wood. The synergistic effect contained the reduction on –OH concentration owing to thermal degradation, and consumption of –OH groups via the interaction (Si–O–Si cross linked networks and Si–O–C covalent bonds) between silica and wood matrix. Furthermore, the degradation of cell wall polymers resulted in the increase of crystallinity in wood. However, the crystallinity turned to decrease due to the amorphous silica impregnation. The silica impregnation could compensate the mass loss caused by thermal degradation, leading to various weight percentage gains (WPGs) that depended on treatment temperature. Moreover, owing to the coverage and penetration of mineral silica in wood, acting as a thermal barrier, the thermal stability and surface hardness of treated wood improved prominently.
    Keywords cell walls ; cellulose ; crystal structure ; dimensional stability ; heat treatment ; hemicellulose ; hydrophobicity ; lignin ; porosity ; silica ; synergism ; temperature ; thermal degradation ; thermal stability ; wood ; wood chemistry
    Language English
    Dates of publication 2022-0301
    Size p. 104-113.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2043250-1
    ISSN 1532-2319 ; 0277-3813
    ISSN (online) 1532-2319
    ISSN 0277-3813
    DOI 10.1080/02773813.2022.2036193
    Database NAL-Catalogue (AGRICOLA)

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