LIVIVO - Search results -

Search results

Result 1 - 10 of total 371

Search options

Article ; Online: Global sensitivity analysis based on multi-objective optimization of rural tourism building performance

Wang, Binghua / Li, Jiwei

Journal of Cleaner Production. 20232023 Sept. 26, June 26, v. 417 p.137917-

2023

Abstract: Morphological design has significant impacts on the performance of rural tourism buildings (RTBs). Multi-objective optimization has been practiced for three prototypes of RTBs in Tianjin, China to explore the RTB design with better energy load, indoor ... ...

Abstract	Morphological design has significant impacts on the performance of rural tourism buildings (RTBs). Multi-objective optimization has been practiced for three prototypes of RTBs in Tianjin, China to explore the RTB design with better energy load, indoor daylighting and thermal comfort performance. However, making decisions from the solution set is still a challenging task for decision-makers. So post-optimization analysis is conducted in this study, and multi-objective optimization solution set of the three RTB types is investigated through global sensitivity analysis (GSA) on the platform of R studio. To begin with, correlation coefficients of the parameters are analyzed by Spearman and partial correlation coefficients methods, and strong correlation relationships are discovered among design parameters of RTBs. Afterwards, Genizi and random forest-based cforest methods are adopted for GSA towards different performance of RTBs, and comprehensive analysis is implemented for the results. Finally, it's found that the depth of frequently used space has significant impacts on annual, cooling and heating load, and daylighting of RTBs. Besides, the height of skylight is discovered to be key important parameter for both cooling and daylighting, and the width as well as the window to wall ratio of the heating space in winter have important influence on winter thermal comfort performance. Overall, the framework and methodology for GSA in post-optimization phase is put forward. The influential mechanism of morphological design parameters on energy load, daylighting and thermal comfort performance of RTBs is explored on basis of the multi-objective optimization solution set. This study not only supplies scientific suggestions for decision-making of RTBs in Tianjin, China, but also offers reference for RTB design and practice in similar regions of the world.
Keywords	cooling ; decision making ; energy ; rural tourism ; winter ; China ; Rural tourism buildings ; Performance ; Post-optimization ; Correlation coefficients ; Global sensitivity analysis
Language	English
Dates of publication	2023-0626
Publishing place	Elsevier Ltd
Document type	Article ; Online
ISSN	0959-6526
DOI	10.1016/j.jclepro.2023.137917
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

Article ; Online: Plasmablastic lymphoma: current knowledge and future directions.

Li, Ji-Wei / Peng, Hong-Ling / Zhou, Xiao-Yan / Wang, Jing-Jing

Frontiers in immunology

2024 Volume 15, Page(s) 1354604

Abstract: Plasmablastic lymphoma (PBL) is an aggressive non-Hodgkin lymphoma associated with HIV infection and immunodeficiency. However, PBL can also be seen immunocompetent individuals in recent studies. PBL was characterized by distinct clinical and ... ...

Abstract	Plasmablastic lymphoma (PBL) is an aggressive non-Hodgkin lymphoma associated with HIV infection and immunodeficiency. However, PBL can also be seen immunocompetent individuals in recent studies. PBL was characterized by distinct clinical and pathological features, such as plasmablastic morphology and universal expression of plasma cell markers. The clinicopathologic features were different between HIV-negative and HIV-positive patients. Gene expression analysis identified the unique molecular feature in PBL, including frequent c-
MeSH term(s)	Humans ; Plasmablastic Lymphoma/diagnosis ; Plasmablastic Lymphoma/genetics ; Plasmablastic Lymphoma/therapy ; HIV Infections/epidemiology ; HIV Infections/complications ; Prognosis ; Plasma Cells/pathology ; HIV Seropositivity
Language	English
Publishing date	2024-02-13
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2024.1354604
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: New insights into the role of macrophages in cancer immunotherapy.

Zhou, Li / Zhao, Tiantian / Zhang, Ruzhe / Chen, Chen / Li, Jiwei

Frontiers in immunology

2024 Volume 15, Page(s) 1381225

Abstract: Macrophages are the main component of the tumor microenvironment, which are differentiated from monocytes in the blood and play an important role in cancer development. Tumor-associated macrophages (TAMs) can promote tumor growth, invasion, metastasis, ... ...

Abstract	Macrophages are the main component of the tumor microenvironment, which are differentiated from monocytes in the blood and play an important role in cancer development. Tumor-associated macrophages (TAMs) can promote tumor growth, invasion, metastasis, and resistance to anti-programmed death receptor 1 therapy by regulating programmed cell death ligand 1 expression and interacting with other immune cells in the tumor microenvironment. However, when activated properly, macrophages can also play an anti-tumor role by enhancing the phagocytosis and cytotoxicity of tumor cells. TAM is associated with poor prognosis and drug resistance in patients treated with immunotherapy, indicating that macrophages are attractive targets for combined therapy in cancer treatment. Combination of targeting TAMs and immunotherapy overcomes the drug resistance and achieved excellent results in some cancers, which may be a promising strategy for cancer treatment in the future. Herein, we review the recent findings on the role of macrophages in tumor development, metastasis, and immunotherapy. We focus mainly on macrophage≥centered therapy, including strategies to deplete and reprogram TAMs, which represent the potential targets for improving tumor immunotherapy efficacy.
MeSH term(s)	Humans ; Macrophages ; Neoplasms ; Immunotherapy ; Phagocytosis ; Tumor Microenvironment
Language	English
Publishing date	2024-03-28
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2024.1381225
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: LncRNA H19 aggravates primary graft dysfunction after lung transplantation via KLF5-mediated activation of CCL28.

Li, Jiwei / Han, Zhijun / Zhu, Zibo / Wei, Li

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

2023 Volume 23, Issue 10, Page(s) 1536–1550

Abstract: The present study aims to elucidate the possible involvement of H19 in primary graft dysfunction (PGD) following lung transplantation (LT) and the underlying mechanism. The transcriptome data were obtained through high-throughput sequencing analysis, and ...

Abstract	The present study aims to elucidate the possible involvement of H19 in primary graft dysfunction (PGD) following lung transplantation (LT) and the underlying mechanism. The transcriptome data were obtained through high-throughput sequencing analysis, and the differential long noncoding RNAs and messenger RNAs were screened for coexpression analysis. The interaction among H19, KLF5 and CCL28 was analyzed. A hypoxia-induced human pulmonary microvascular endothelial cell injury model was established, in which H19 was knocked down to elucidate its effect on the lung function, inflammatory response, and cell apoptosis. An orthotopic left LT model was constructed for in vivo mechanistic validation. High-throughput transcriptome sequencing analysis revealed the involvement of the H19/KLF5/CCL28 signaling axis in PGD. Silencing of H19 reduced inflammatory response and thus improved PGD. CCL28 secreted by human pulmonary microvascular endothelial cells after LT recruited neutrophils and macrophages. Mechanistic investigations indicated that H19 augmented the expression of CCL28 by binding to the transcription factor KLF5. Abundant expression of CCL28 reversed the alleviating effect of H19 silencing on PGD. In conclusion, the results point out that H19 exerts a promoting effect on PGD through increasing KLF5 expression and the subsequent CCL28 expression. Our study provides a novel insight into the mechanism of action of H19.
MeSH term(s)	Humans ; RNA, Long Noncoding/genetics ; Endothelial Cells/metabolism ; Primary Graft Dysfunction/etiology ; Gene Expression Regulation ; Lung Transplantation/adverse effects ; MicroRNAs/genetics ; Chemokines, CC/genetics ; Chemokines, CC/metabolism ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism
Chemical Substances	RNA, Long Noncoding ; MicroRNAs ; CCL28 protein, human ; Chemokines, CC ; KLF5 protein, human ; Kruppel-Like Transcription Factors
Language	English
Publishing date	2023-06-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2060594-8
ISSN	1600-6143 ; 1600-6135
ISSN (online)	1600-6143
ISSN	1600-6135
DOI	10.1016/j.ajt.2023.06.015
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 5542: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Multi-layer CNN-LSTM network with self-attention mechanism for robust estimation of nonlinear uncertain systems.

Liu, Lin / Feng, Jun / Li, Jiwei / Chen, Wanxin / Mao, Zhizhong / Tan, Xiaowei

Frontiers in neuroscience

2024 Volume 18, Page(s) 1379495

Abstract: Introduction: With the help of robot technology, intelligent rehabilitation of patients with lower limb motor dysfunction caused by stroke can be realized. A key factor constraining the clinical application of rehabilitation robots is how to realize ... ...

Abstract	Introduction: With the help of robot technology, intelligent rehabilitation of patients with lower limb motor dysfunction caused by stroke can be realized. A key factor constraining the clinical application of rehabilitation robots is how to realize pattern recognition of human movement intentions by using the surface electromyography (sEMG) sensors to ensure unhindered human-robot interaction. Methods: A multilayer CNN-LSTM prediction network incorporating the self-attention mechanism (SAM) is proposed, in this paper, which can extract and learn the periodic and trend characteristics of the sEMG signals, and realize the accurate autoregressive prediction of the human motion information. Firstly, the multilayer CNN-LSTM network utilizes the CNN layer for initial feature extraction of data, and the LSTM network is used to improve the enhancement of the historical time-series features. Then, the SAM is used to improve the global feature extraction performance and parallel computation speed of the network. Results: In comparison with existing test is carried out using actual data from five healthy subjects as well as a clinical hemiplegic patient to verify the superiority and practicality of the proposed algorithm. The results show that most of the model's prediction Discussion: The main contribution of this paper is to realize continuous motion estimation of ankle joint for healthy and hemiplegic individuals under non-ideal conditions (weak sEMG signals, muscle fatigue, high muscle tension, etc.), which improves the pattern recognition accuracy and robustness of the sEMG sensor-based system.
Language	English
Publishing date	2024-04-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2024.1379495
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Association between electrocardiographic abnormalities and flood exposure among middle-aged and elderly people: A national longitudinal study in China.

Li, Pengfei / Wu, Jingyi / Li, Jiwei / Tong, Mingkun / Liu, Yuanli / Xue, Tao / Guan, Tianjia

Environment international

2024 Volume 185, Page(s) 108484

Abstract: Background: Flooding has become more frequent and intensive due to climate change, particularly in Asian countries. However, evidence on the long-term health effects of floods from large-scale studies on the vulnerable aged population in China is ... ...

Abstract	Background: Flooding has become more frequent and intensive due to climate change, particularly in Asian countries. However, evidence on the long-term health effects of floods from large-scale studies on the vulnerable aged population in China is insufficient. This study analyzed the long-term effects of exposure to flood on electrocardiographic (ECG) abnormalities, a commonly used indicator of cardiovascular disease (CVD) screening, in middle-aged and elderly people. Method: We evaluated the Chinese National Stroke Screening Survey data of 80,711 follow-up records from 38,375 participants aged > 40 years with two or more visits between 2013 and 2018 in this longitudinal study. Flood exposure was assessed as the presence of a satellite-detected flooded area within 500 m of the residence within 5 years before the survey date. The association between ECG abnormalities and flood exposure was analyzed using a random effects model with multiple adjustments. As age is an important CVD risk factor, a varying-coefficient function was derived to estimate the nonlinear modifying effect of age on the association between ECG abnormalities and flood exposure. The strata-specific associations between ECG abnormalities and flood exposure were applied to characterize vulnerability to flood. Results: The fully adjusted model suggested that flood exposure was associated with an increased risk for ECG abnormalities among the middle-aged and elderly population (odds ratio [OR] 1.74, 95 % confidence interval [CI] 1.49, 2.03). The ORs of flood exposure for ECG suggesting atrial fibrillation, ST depression, and left ventricular hypertrophy were 1.85 (95 % CI 1.16, 2.94), 6.92 (95 % CI 5.23, 9.16), and 1.55 (95 % CI 0.66, 3.65), respectively. These associations were generally robust in various subpopulations, while a sublinear curve for the negative modifying effect of age was observed on the population vulnerability to flood. Conclusion: Flood exposure was associated with an increased long-term risk for an ECG abnormality. The need for effective measures to mitigate vulnerability to flood is not negligible in China.
MeSH term(s)	Middle Aged ; Humans ; Aged ; Floods ; Longitudinal Studies ; Stroke ; Atrial Fibrillation/epidemiology ; China/epidemiology
Language	English
Publishing date	2024-02-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2024.108484
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3131: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Neonatal jaundice caused by compound mutations of SLC10A1 and a novel UGT1A1 gene.

Wang, Meifen / Chen, Tao / Chen, Rui / Bi, Zhongrui / Peng, Junchao / Shao, Qi / Li, Jiwei

Clinics and research in hepatology and gastroenterology

2024 Volume 48, Issue 5, Page(s) 102340

MeSH term(s)	Female ; Humans ; Glucuronosyltransferase/genetics ; Jaundice, Neonatal/genetics ; Mutation ; Organic Anion Transporters, Sodium-Dependent/genetics ; Symporters/genetics ; Infant
Chemical Substances	Glucuronosyltransferase (EC 2.4.1.17) ; Organic Anion Transporters, Sodium-Dependent ; sodium-bile acid cotransporter (145420-23-1) ; Symporters ; UGT1A1 enzyme (EC 2.4.1.-)
Language	English
Publishing date	2024-04-06
Publishing country	France
Document type	Letter ; Case Reports
ZDB-ID	2594333-9
ISSN	2210-741X ; 2210-7401
ISSN (online)	2210-741X
ISSN	2210-7401
DOI	10.1016/j.clinre.2024.102340
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: Sodium taurocholate cotransporter polypeptide deficiency from two pairs of twins with homozygous and heterozygous of p.Ser267Phe variant, respectively: Case report.

Wang, Meifen / Chen, Tao / Li, Meirui / Chen, Rui / Peng, Junchao / Li, Jiwei

Clinics and research in hepatology and gastroenterology

2024 Volume 48, Issue 3, Page(s) 102303

MeSH term(s)	Humans ; Homozygote ; Heterozygote ; Peptides ; Taurocholic Acid ; Symporters ; Organic Anion Transporters, Sodium-Dependent ; Bile Acids and Salts
Chemical Substances	Peptides ; Taurocholic Acid (5E090O0G3Z) ; Symporters ; Organic Anion Transporters, Sodium-Dependent ; Bile Acids and Salts
Language	English
Publishing date	2024-02-16
Publishing country	France
Document type	Case Reports ; Letter
ZDB-ID	2594333-9
ISSN	2210-741X ; 2210-7401
ISSN (online)	2210-741X
ISSN	2210-7401
DOI	10.1016/j.clinre.2024.102303
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: A new method of estimating soil water diffusivity based on variation in the wetting front position and on the principle of stationary action

Li, Jiwei / Jin, Hui / Wang, Chunling / Wang, Huabin

Journal of hydrology. 2022 Sept., v. 612

2022

Abstract: This paper presents a novel method for the estimation of soil water diffusivity that solves the nongravitational Richards equation using the variation in the boundary of the advancing wetting front. The solution is based on the principle of stationary ... ...

Abstract	This paper presents a novel method for the estimation of soil water diffusivity that solves the nongravitational Richards equation using the variation in the boundary of the advancing wetting front. The solution is based on the principle of stationary action. The position of the wetting front is determined from the continuity of water content at the wetting front interface, as the underlying physical principles of this area are well known and thus it can be described using relatively few assumptions. This also eliminates the need for the Boltzmann-transformation, which is commonly required in traditional methods. The Brooks-Corey empirical water diffusion function is used to analytically determine the significant parameters of diffusivity. The soil water diffusivities of 15 soil samples matched well with their measured soil–water diffusivities, thereby confirming the reliability of the method. All of the measurements required for using this method are rapidly and easily obtained, and the experimental apparatus is simple and inexpensive. Compared with other methods, this novel method is more accurate and convenient for use in laboratories for measuring the soil hydraulic properties.
Keywords	diffusivity ; equations ; soil water ; water content
Language	English
Dates of publication	2022-09
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1473173-3
ISSN	1879-2707 ; 0022-1694
ISSN (online)	1879-2707
ISSN	0022-1694
DOI	10.1016/j.jhydrol.2022.128290
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Free particulate organic carbon plays critical roles in carbon accumulations during grassland succession since grazing exclusion

Li, Jiwei / Shangguan, Zhouping / Deng, Lei

Soil & tillage research. 2022 Mar. 21,

2022

Abstract: Grazing exclusion is proposed as an effective strategy for to recover degraded grasslands and increase carbon accumulation. However, few studies have explored the response of soil organic carbon (SOC) and its components to grazing exclusion during long- ... ...

Abstract	Grazing exclusion is proposed as an effective strategy for to recover degraded grasslands and increase carbon accumulation. However, few studies have explored the response of soil organic carbon (SOC) and its components to grazing exclusion during long-term succession. In this study, we collected soils from sites with a chronosequence of ~33 years after grazing exclusion with randomized and replicated experiments in the temperate grasslands of the Loess Plateau, China. The contents of SOC, free particulate organic carbon (fPOC), occluded particulate organic carbon (oPOC), and mineral-associated organic carbon (MOC) and their key driving factors in the 0–60cm soil layer were examined in each grassland. The results showed that fPOC, oPOC, and MOC contents were significantly affected (P<0.05) by grazing exclusion duration and soil depth. Soil fPOC, oPOC, POC, and MOC contents increased with exclusion time, but decreased with soil depth. SOC content was significantly improved since grazing exclusion for more than 26 years compared with that for active grazing grasslands. The fPOC played critical roles in promoting the SOC formation within the entire soil profile (0–60cm depth). Across the sampled areas, we found a positive association between the concentrations of SOC and its fractions and the input of litter to the topsoil (0–40cm), and soil extracellular enzymes at greater depths (40–60cm). Our results indicate the potential of grazing exclusion for promoting SOC accumulation in semiarid regions, and highlight the need to understand soil carbon stabilization mechanisms in both top- and subsoil under future climate change scenarios.
Keywords	chronosequences ; climate change ; grasslands ; particulate organic carbon ; research ; soil depth ; soil organic carbon ; soil profiles ; subsoil ; tillage ; topsoil ; China
Language	English
Dates of publication	2022-0321
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ZDB-ID	406698-4
ISSN	0167-1987
ISSN	0167-1987
DOI	10.1016/j.still.2022.105380
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 3643: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

To top

Full text online

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED