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  1. Article: [Clinical effects of free descending branch tissue flap of lateral circumflex femoral artery in repairing Wagner grade 3 or 4 diabetic foot wounds].

    Yang, L / Li, K L / Pang, Y X / Zhou, W C

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2023  Volume 38, Issue 12, Page(s) 1148–1155

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Female ; Humans ; Plastic Surgery Procedures ; Wound Healing ; Cicatrix/surgery ; Femoral Artery/surgery ; Diabetic Foot/surgery ; Blood Glucose ; Soft Tissue Injuries/surgery ; Skin Transplantation ; Free Tissue Flaps ; Treatment Outcome ; Perforator Flap/blood supply ; Diabetes Mellitus
    Chemical Substances Blood Glucose
    Language Chinese
    Publishing date 2023-01-19
    Publishing country China
    Document type Observational Study ; English Abstract ; Journal Article
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501225-20220321-00076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [The effect of OSAHS on middle ear and inner ear vestibule function advances].

    Li, K L / Li, J R

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2018  Volume 30, Issue 10, Page(s) 841–844

    Abstract: Obstructive sleep apnea hypopnea syndrome(OSAHS) as a common frequentlyoccurring disease, it can cause repeated episodes of hypoxaemia and hypercapnia during sleep. With long period of hypoxaemia, obvious pathological changes and dysfunction emerged in ... ...

    Abstract Obstructive sleep apnea hypopnea syndrome(OSAHS) as a common frequentlyoccurring disease, it can cause repeated episodes of hypoxaemia and hypercapnia during sleep. With long period of hypoxaemia, obvious pathological changes and dysfunction emerged in heart，brain and lung then all kinds of clinical symptoms appear. Because of the middle ear and inner ear themselves anatomical characteristics and blood supply of regulating mechanism， they often has been damaged before the other important organ damage. As scholars have indepth study of the auditory system complications in patients with OSAHS, various influence of OSAHS on the middle ear，inner ear also gradually be known.This paper will review the effect of OSAHS on middle ear， inner ear and vestibule function, hope to have some application value for clinical work.
    MeSH term(s) Ear, Middle ; Humans ; Hypercapnia/etiology ; Hypoxia/etiology ; Sleep Apnea, Obstructive/complications ; Vestibule, Labyrinth
    Language Chinese
    Publishing date 2018-09-26
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1001-1781
    ISSN 1001-1781
    DOI 10.13201/j.issn.1001-1781.2016.10.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Analysis of the vaccination status of enterovirus type 71 inactivated vaccine in China from 2017 to 2021].

    Zhang, L / Cao, L / Li, Y / Hu, Y X / Tang, L / Li, K L / Yin, Z D / An, Z J

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2023  Volume 44, Issue 4, Page(s) 561–567

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Enterovirus A, Human ; Hand, Foot and Mouth Disease/epidemiology ; Hand, Foot and Mouth Disease/prevention & control ; Vaccines, Inactivated ; Viral Vaccines ; Enterovirus ; Vaccination ; China/epidemiology
    Chemical Substances Vaccines, Inactivated ; Viral Vaccines
    Language Chinese
    Publishing date 2023-05-06
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20220811-00704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Additive manufacturing of anti-bacterial and low-cost Ti–Mo(–Ag) alloys using elemental powders through in situ laser alloying

    Xu, J. Y. / Li, K. L. / Tang, J. C. / Zhou, Y. H. / Luo, J. P. / Tang, W. / Lai, Y. X. / Dargusch, M. S. / Yan, M.

    J Mater Sci. 2023 Feb., v. 58, no. 5, p. 2268-2293

    2023  , Page(s) 2268–2293

    Abstract: The Ti–15Mo alloy has become a widely recognized biomedical Ti alloy due to its excellent properties, including a low Young’s modulus that is close to that of a human bone. Selective laser melting (SLM) additive manufacturing (AM) offers both advanced ... ...

    Abstract The Ti–15Mo alloy has become a widely recognized biomedical Ti alloy due to its excellent properties, including a low Young’s modulus that is close to that of a human bone. Selective laser melting (SLM) additive manufacturing (AM) offers both advanced manufacturing capabilities to the processing of the alloy and the potential to make customized implants. The feedstock cost of pre-alloyed Ti–15Mo powder, however, is high, like that of many other Ti alloys, and can be a major obstacle to the wider application of the AM technique. This study focused on mitigating this problem by using an in situ laser alloying approach, wherein a low-cost hydride-dehydrate (HDH) Ti powder was mechanically mixed with elemental Mo powder to form a composite powder feedstock (i.e., Ti + Mo). The Ti–15Mo alloy could be printed with a high relative density (~ 99.76%). A finite element simulation was performed to study the melt pool during the SLM process with subsequent detailed discussions to understand the in situ alloying mechanism. Mechanical property indicates the as-printed Ti–15Mo has high strength (~ 1170 MPa) but low ductility, while the latter has been much improved by introducing a merely 0.2 wt% of yttrium (Y). Based on the optimized Ti–15Mo–0.2Y alloy with a strength of ~ 1300 MPa and a modulus of ~ 85 GPa, different amounts of elemental Ag powder were further alloyed in situ to acquire antibacterial properties. Compared with the antibacterial activity of the control group, that of the final material, i.e., in situ laser alloyed Ti–15Mo–0.2Y–2.5Ag, reached 92–95%; the addition of Ag had a minimal effect on the cell viability. In vivo experiments demonstrated the Ag-containing alloys to exhibit good biocompatibility.
    Keywords alloys ; antibacterial properties ; biocompatibility ; cell viability ; feedstocks ; finite element analysis ; humans ; mechanical properties ; yttrium
    Language English
    Dates of publication 2023-02
    Size p. 2268-2293
    Publishing place Springer US
    Document type Article ; Online
    ZDB-ID 2015305-3
    ISSN 1573-4803 ; 0022-2461
    ISSN (online) 1573-4803
    ISSN 0022-2461
    DOI 10.1007/s10853-022-08107-6
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: [A Meta-analysis of comparing effectiveness and safety between minimally invasive video-assisted thyroidectomy and conventional thyroidectomy in the treatment of papillary thyroid carcinoma without lymph node metastasis].

    Zhang, J / Yao, K / Li, K L

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2018  Volume 31, Issue 18, Page(s) 1435–1441

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Carcinoma, Papillary/surgery ; Humans ; Lymphatic Metastasis ; Minimally Invasive Surgical Procedures ; Thyroid Cancer, Papillary ; Thyroid Neoplasms/surgery ; Thyroidectomy/methods ; Video-Assisted Surgery
    Language Chinese
    Publishing date 2018-05-24
    Publishing country China
    Document type Journal Article ; Meta-Analysis
    ISSN 1001-1781
    ISSN 1001-1781
    DOI 10.13201/j.issn.1001-1781.2017.18.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Treatment effects of sandwich-shaped resection and cheiloplasty applied in macrocheilia secondary to arteriovenous malformations].

    Tai, M Z / Chen, T / Ge, C X / Xu, Z G / Li, K L / Qin, Z P

    Zhonghua yi xue za zhi

    2022  Volume 102, Issue 23, Page(s) 1771–1774

    Abstract: To summarize the clinical experience of sandwich-shaped resection and cheiloplasty in the treatment of macrocheilia secondary to arteriovenous malformation, and to observe its clinical efficacy and complications. The clinical data of 27 patients with ... ...

    Abstract To summarize the clinical experience of sandwich-shaped resection and cheiloplasty in the treatment of macrocheilia secondary to arteriovenous malformation, and to observe its clinical efficacy and complications. The clinical data of 27 patients with macrocheilia secondary to arteriovenous malformation who received surgical treatment from January 2018 to October 2020 in Linyi Cancer Hospital were retrospectively analyzed. There were 14 males and 13 females. The median age was 4.5 years (ranged from 2 to 57 years). There were 18 cases of upper lip and 9 cases of lower lip. All patients had received interventional embolization sclerotherapy for 5 to 10 times before surgery with unsatisfied effect. There was no obvious improvement in the appearance,whereas 3 cases progressed presenting as abnormal enlargement. Sandwich-shaped resection and cheiloplasty was performed in all the patients. Histopathological examinations confirmed arteriovenous malformations in all 27 cases. Twenty-six patients received one course of operation and one received two courses. Partial mucosal necrosis occurred in 1 case and healed after dressing change, while the rest healed by first intention. Local recurrence occurred in 2 cases within 6 months after operation. A four-level standard was used for long-term evaluation, and 24 cases got grade Ⅲ (good), three cases got grade Ⅱ (moderate) after 1 to 3 years of follow-up. Sandwich-shaped resection and cheiloplasty can achieve good long-term efficacy with excellent appearance and function. Due to its advantages of hidden incision and three-dimensional resection and reservation, it is worthy of further clinical promotion.
    MeSH term(s) Adolescent ; Adult ; Arteriovenous Malformations/therapy ; Child ; Child, Preschool ; Embolization, Therapeutic/methods ; Female ; Humans ; Lip ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; Young Adult
    Language Chinese
    Publishing date 2022-06-06
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20211231-02940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A likely inverse-Compton emission from the Type IIb SN 2013df.

    Li, K L / Kong, A K H

    Scientific reports

    2016  Volume 6, Page(s) 30638

    Abstract: The inverse-Compton X-ray emission model for supernovae has been well established to explain the X-ray properties of many supernovae for over 30 years. However, no observational case has yet been found to connect the X-rays with the optical lights as ... ...

    Abstract The inverse-Compton X-ray emission model for supernovae has been well established to explain the X-ray properties of many supernovae for over 30 years. However, no observational case has yet been found to connect the X-rays with the optical lights as they should be. Here, we report the discovery of a hard X-ray source that is associated with a Type II-b supernova. Simultaneous emission enhancements have been found in both the X-ray and optical light curves twenty days after the supernova explosion. While the enhanced X-rays are likely dominated by inverse-Compton scatterings of the supernova's lights from the Type II-b secondary peak, we propose a scenario of a high-speed supernova ejecta colliding with a low-density pre-supernova stellar wind that produces an optically thin and high-temperature electron gas for the Comptonization. The inferred stellar wind mass-loss rate is consistent with that of the supernova progenitor candidate as a yellow supergiant detected by the Hubble Space Telescope, providing an independent proof for the progenitor. This is also new evidence of the inverse-Compton emission during the early phase of a supernova.
    Language English
    Publishing date 2016-08-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep30638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Analysis of FBN1 genemutations in a pedigree with Marfan syndrome].

    Zheng, Q / Li, K L / Dai, G L / Xiong, D / Yao, M Y / Chen, X / Li, Y M / Zhang, Y Y / Li, H R / Cao, Y

    Zhonghua yi xue za zhi

    2022  Volume 102, Issue 34, Page(s) 2702–2706

    Abstract: Mutations in fibrillin-1 (FBN1) were detected in an autosomal dominant Marfan syndrome (MFS) pedigree. The related phenotypes and the significance of mutation screening were discussed. Complete medical and cardiovascular examinations for all pedigree ... ...

    Abstract Mutations in fibrillin-1 (FBN1) were detected in an autosomal dominant Marfan syndrome (MFS) pedigree. The related phenotypes and the significance of mutation screening were discussed. Complete medical and cardiovascular examinations for all pedigree members were performed. Whole exons sequencing (WES) was used to sequence the DNA of the patients and their relatives. The potential pathogenic mutation sites were screened by bioinformatics method. Sanger sequencing was used to verify the mutation sites in the pedigree. The results showed that FBN1 missense mutation was c.6806 T>C in exon 56, resulting in isoleucine being replaced by threonine (p. Ile2269Thr). This mutation has not been reported in Chinese Han population. The occurrence of the mutations strongly correlated with the phenotypes of the patients. The results expand the mutation spectrum of FBN1, and it is helpful to further explore the molecular pathogenesis of MFS and MFS related diseases.
    MeSH term(s) Exons ; Fibrillin-1/genetics ; Humans ; Marfan Syndrome/diagnosis ; Marfan Syndrome/genetics ; Marfan Syndrome/pathology ; Mutation, Missense ; Pedigree
    Chemical Substances FBN1 protein, human ; Fibrillin-1
    Language Chinese
    Publishing date 2022-09-12
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20220531-01200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Clinical research progress and implications of therapeutic vaccines for cervical cancer and precancerous lesions: a qualitative systematic review].

    Cai, S / Miao, K / Tan, X Y / Cheng, S / Li, D T / Zeng, X Y / Yang, Y / Meng, R R / Liu, Z K / Li, Y / Li, K L / Sun, F / Zhan, S Y

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2022  Volume 44, Issue 7, Page(s) 743–760

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Cancer Vaccines/therapeutic use ; Cervical Intraepithelial Neoplasia/prevention & control ; Female ; Humans ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines/therapeutic use ; Precancerous Conditions/therapy ; Uterine Cervical Neoplasms/prevention & control
    Chemical Substances Cancer Vaccines ; Papillomavirus Vaccines
    Language Chinese
    Publishing date 2022-07-20
    Publishing country China
    Document type Journal Article ; Systematic Review
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.cn112152-20210824-00638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Artificial intelligence-based literature data warehouse for vaccine safety].

    Yang, Y / Zeng, X Y / Liu, Z K / Li, Z X / Zhao, H Y / Liu, Z X / Li, P / Yao, X Y / He, B J / Li, K L / Li, Y / Sun, F / Zhan, Siyan

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2022  Volume 43, Issue 3, Page(s) 431–435

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Artificial Intelligence ; Data Warehousing ; Humans ; Tetanus ; Tetanus Toxoid ; Whooping Cough/prevention & control
    Chemical Substances Tetanus Toxoid
    Language Chinese
    Publishing date 2022-03-28
    Publishing country China
    Document type Journal Article ; Systematic Review
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20210407-00288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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