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  1. Article ; Online: Correlation of

    Li, L-J / Xuan, J-Z / Zheng, H-N

    Clinical radiology

    2023  Volume 78, Issue 7, Page(s) e502–e509

    Abstract: Aim: To explore the association between metabolic parameters evaluated by integrated 2-[: Materials and methods: This study included 134 patients. Metabolic parameters were obtained by PET/CT. Immunohistochemistry analysis was used for FOXP3-TILs ( ... ...

    Abstract Aim: To explore the association between metabolic parameters evaluated by integrated 2-[
    Materials and methods: This study included 134 patients. Metabolic parameters were obtained by PET/CT. Immunohistochemistry analysis was used for FOXP3-TILs (transcription factor forkhead box protein 3 tumour-infiltrating lymphocytes), CD8-TILs, CD4-TILs, CD68-TAMs (tumour-associated macrophages) and galectin-1 (Gal-1) tumour expression.
    Results: There were significant positive associations between FDG PET metabolic parameters and the median percentage of immune reactive areas (IRA%) covered by FOXP3-TILs and CD68-TAMs. Negative associations with the median IRA% covered by CD4-TILs and CD8-TILs were observed: maximal standardised uptake value (SUV
    Conclusion: FDG PET may facilitate a comprehensive evaluation of the tumour microenvironment and predict response to immunotherapy.
    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Fluorodeoxyglucose F18 ; Radiopharmaceuticals ; Tumor Microenvironment ; Prognosis ; Positron-Emission Tomography/methods ; Adenocarcinoma of Lung/diagnostic imaging ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Biomarkers ; Retrospective Studies ; Tumor Burden
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Radiopharmaceuticals ; 1-nitrohydroxyphenyl-N-benzoylalanine (59921-69-6) ; Biomarkers
    Language English
    Publishing date 2023-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 391227-9
    ISSN 1365-229X ; 0009-9260
    ISSN (online) 1365-229X
    ISSN 0009-9260
    DOI 10.1016/j.crad.2023.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Considerations on the standardized diagnosis and treatment of iron-deficiency anemia].

    Li, L J / Zhang, L S

    Zhonghua yi xue za zhi

    2021  Volume 101, Issue 40, Page(s) 3266–3270

    Abstract: The prevalence of iron-deficiency anemia (IDA) is high in China, especially among children, the elderly and pregnant women. It can be associated with a variety of diseases involving major systems, and even cause irreversible damage to the immune and ... ...

    Abstract The prevalence of iron-deficiency anemia (IDA) is high in China, especially among children, the elderly and pregnant women. It can be associated with a variety of diseases involving major systems, and even cause irreversible damage to the immune and nervous system. It is noteworthy that only less than 20% of the IDA population have access to timely treatment. This requires attention towards the standardized diagnosis and treatment of IDA with multidisciplinary collaboration. This article reviews the recent research updates of IDA, revealing the new findings in the harms of IDA, current challenges in the treatment of IDA, and the latest research and development progress of intravenous iron. The aim is to provide guidance and suggestions on timely diagnosis and proper treatment of IDA.
    MeSH term(s) Administration, Intravenous ; Aged ; Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/therapy ; Child ; China ; Female ; Humans ; Iron ; Pregnancy ; Prevalence
    Chemical Substances Iron (E1UOL152H7)
    Language Chinese
    Publishing date 2021-11-10
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20210609-01319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [The role of narrow band imaging laryngoscope in the examination of esophageal cancer with multiple primary laryngeal cancer].

    Li, L J / Ni, X G

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2021  Volume 56, Issue 5, Page(s) 546–547

    MeSH term(s) Esophageal Neoplasms/diagnostic imaging ; Humans ; Laryngeal Neoplasms/diagnostic imaging ; Laryngoscopes ; Narrow Band Imaging ; Neoplasms, Multiple Primary
    Language Chinese
    Publishing date 2021-05-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20201215-00922
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  4. Article: [Holistic view of surgery based on membrane anatomy for gastrointestinal tumor].

    Xi, H / Li, L J / Sun, L Y

    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

    2021  Volume 24, Issue 7, Page(s) 560–566

    Abstract: The mesentery is a continuous unity and the operation of digestive carcinoma is the process of mesenteric resection. This paper attempts to simplify the formation process of all kinds of fusion fascia in the process of digestive tract embryogenesis, and ... ...

    Abstract The mesentery is a continuous unity and the operation of digestive carcinoma is the process of mesenteric resection. This paper attempts to simplify the formation process of all kinds of fusion fascia in the process of digestive tract embryogenesis, and to illuminate the continuity of fusion fascia with a holistic concept. This is helpful for beginners to reversely dissect the fusion fascia and maintain the correct surgical plane during operation, and to achieve the purpose of complete mesenteric resection.
    MeSH term(s) Colonic Neoplasms/surgery ; Gastrointestinal Neoplasms/surgery ; Humans ; Laparoscopy ; Mesentery/surgery ; Mesocolon
    Language Chinese
    Publishing date 2021-07-21
    Publishing country China
    Document type Journal Article
    ISSN 1671-0274
    ISSN 1671-0274
    DOI 10.3760/cma.j.cn.441530-20210413-00161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Postauricular hairline plus temporal approach gasless full-endoscopic parotidectomy for tumors in deep lobe of parotid gland: a 16-case report].

    Wei, H X / Chen, S / Yang, F / Wang, X Y / Li, C J / Li, L J / Zhu, G Q

    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

    2024  Volume 59, Issue 2, Page(s) 173–177

    Abstract: To investigate the safety and feasibility of gasless total endoscopic resection of deep lobe parotid gland tumors via a postauricular hairline plus temporal approach. The approach was designed as: a 4 to 5 cm main incision was designed at the ... ...

    Abstract To investigate the safety and feasibility of gasless total endoscopic resection of deep lobe parotid gland tumors via a postauricular hairline plus temporal approach. The approach was designed as: a 4 to 5 cm main incision was designed at the postauricular hairline, and a 0.5 cm auxiliary incision was designed in the temporal hairline. The operating cavity was established with the assistance of a special retractor. "Anterograde" dissection of the facial nerve was performed throughout the procedure, along with partial or total gland removal of the tumor. All 16 operations were successfully completed without conversion to open surgery. During the operation, the trunk and branches of the facial nerve were completely preserved, the tumor was completely removed, and the incision healed. Six patients had mild facial paralysis after operation, and recovered completely after 3 to 6 months. There was no salivary fistula, Frey syndrome, infection, or other complications. The postoperative incision was concealed and the aesthetic effect was good. The postauricular hairline plus temporal approach gasless total endoscopic parotidectomy is safe and feasible. This technique can achieve the complete dissection of the total trunk to the branches of the facial nerve, and has good access to the tumors located in any part of the parotid gland region. On the basis of radical resection of the tumor, it achieves minimally invasive and aesthetic improvement.
    MeSH term(s) Humans ; Parotid Gland/surgery ; Esthetics, Dental ; Parotid Neoplasms/surgery ; Endoscopy/methods ; Facial Paralysis/etiology ; Postoperative Complications
    Language Chinese
    Publishing date 2024-01-25
    Publishing country China
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 1027950-7
    ISSN 1002-0098
    ISSN 1002-0098
    DOI 10.3760/cma.j.cn112144-20231025-00218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Research progress in mitochondrial transfer mediated by tunneling nanotube in the field of tumor].

    Huang, N W / Qiao, X H / Li, L J

    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

    2021  Volume 56, Issue 10, Page(s) 1045–1049

    Abstract: Mitochondria, as the main site of cell metabolism and energy generation, contains the genome encoding the respiratory chain-associated complexes. Deletions or mutations of mitochondria will lead to mitochondrial respiratory chain deficiencies and these ... ...

    Abstract Mitochondria, as the main site of cell metabolism and energy generation, contains the genome encoding the respiratory chain-associated complexes. Deletions or mutations of mitochondria will lead to mitochondrial respiratory chain deficiencies and these deficiencies play an important role in metabolic reprogramming which is considered as one of the important features of tumorigenesis and development. Many studies have found that tunneling nanotube (TNT), a well-established mitochondrial transfer pathway, is able to restore mitochondrial respiratory deficiencies. This review article focuses on the occurrence of mitochondrial transfer, the mechanism of TNT formation and the promising therapeutic targets acting on mitochondrial transfer.
    MeSH term(s) Humans ; Mitochondria ; Mutation ; Nanotubes ; Neoplasms
    Language Chinese
    Publishing date 2021-09-30
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 1027950-7
    ISSN 1002-0098
    ISSN 1002-0098
    DOI 10.3760/cma.j.cn112144-20210320-00131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Hemophagocytic syndrome with elevated alpha-fetoprotein: 3 cases report and literature review].

    Liu, Y M / Zhang, W / Cao, Q Y / Xie, X Y / Li, L J / Fu, R / Shao, Z H / Song, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2024  Volume 44, Issue 12, Page(s) 1038–1040

    MeSH term(s) Humans ; Lymphohistiocytosis, Hemophagocytic ; alpha-Fetoproteins
    Chemical Substances alpha-Fetoproteins
    Language Chinese
    Publishing date 2024-03-19
    Publishing country China
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.12.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Use of antidepressants following hysterectomy with or without oophorectomy: A national sample in the US.

    Li, L J / Chen, Q / Zhang, N / Yao, X / Wang, C X

    Maturitas

    2022  Volume 167, Page(s) 32–38

    Abstract: Objective: Hysterectomy is one of the most common gynecological surgeries conducted around the world. Previous studies reported inconsistent results on depressive symptoms experienced after hysterectomy. This study explored the association between ... ...

    Abstract Objective: Hysterectomy is one of the most common gynecological surgeries conducted around the world. Previous studies reported inconsistent results on depressive symptoms experienced after hysterectomy. This study explored the association between hysterectomy with or without oophorectomy and the use of antidepressants.
    Study design: This cross-sectional study included 4888 subjects between 20 and 80 years old who participated in the US National Health and Nutrition Examination Survey (NHANES) between 2015 and 2018. The associations between hysterectomy with or without oophorectomy and the use of antidepressants were estimated using multivariable logistic regression models.
    Main outcome measures: There was a positive relationship between hysterectomy, both with and without oophorectomy, and the use of antidepressants after adjusting for all potential confounders (OR = 2.13, 95 % CI = 1.43-3.17, p = 0.000; OR = 2.04, 95 % CI = 1.35-3.06 p = 0.001). In the subgroup analysis stratified by race, a positive association between hysterectomy without oophorectomy was found among non-Hispanic white women (OR = 1.89, 95 % CI = 1.04-3.44, p = 0.038) and women of other races (OR = 3.14, 95 % CI = 1.30-7.56, p = 0.010), and a positive association between hysterectomy with oophorectomy was found among non-Hispanic black women (OR = 3.09, 95 % CI = 1.15-8.27, p = 0.024). However, no association was found among non-Hispanic black and Mexican American women who had undergone hysterectomy with oophorectomy, and it was not reported in women of non-Hispanic white, Mexican American or other race who underwent hysterectomy with oophorectomy.
    Conclusion: This study suggested that hysterectomy was significantly associated with antidepressant use, but the extent of the associations may vary by race.
    MeSH term(s) Female ; Humans ; Aged ; Aged, 80 and over ; Nutrition Surveys ; Cross-Sectional Studies ; Ovariectomy/adverse effects ; Hysterectomy/adverse effects ; Hysterectomy/methods ; Antidepressive Agents/therapeutic use
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2022-09-30
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 80460-5
    ISSN 1873-4111 ; 0378-5122
    ISSN (online) 1873-4111
    ISSN 0378-5122
    DOI 10.1016/j.maturitas.2022.09.010
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  9. Article: [Analysis on epidemiological characteristics of allergens with allergic skin diseases in a hospital in Beijing City from 2017 to 2021].

    Li, L J / Peng, C Y / Li, Z Y / Liu, P / Yan, C L / Zhao, Z T

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2023  Volume 57, Issue 12, Page(s) 2188–2195

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Adult ; Animals ; Dogs ; Humans ; Female ; Male ; Adolescent ; Child, Preschool ; Child ; Allergens ; Dermatitis, Atopic/epidemiology ; Retrospective Studies ; Hospitals ; Immunoglobulin E
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0)
    Language Chinese
    Publishing date 2023-12-28
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20230825-00122
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  10. Article: [Factors associated with malnutrition in infants with congenital heart disease within one year after surgery].

    Li, L J / Hu, C M / Gong, T / Zhang, L F / Li, X W / Xiao, X W / Cui, Y Q

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2023  Volume 61, Issue 5, Page(s) 440–445

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Humans ; Female ; Cardiac Surgical Procedures ; Retrospective Studies ; Malnutrition/complications ; Heart Defects, Congenital/surgery ; Risk Factors ; Length of Stay ; Infant Nutrition Disorders/complications
    Language Chinese
    Publishing date 2023-04-24
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20220909-00794
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