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  1. Book ; Thesis: Overexpression of eukaryotic initiation factor 4F

    Li, Mao Liang

    a therapeutic target in cholangiocarcinoma

    2018  

    Institution Universität Heidelberg
    Author's details vorgelegt von Mao Li
    Language English
    Size viii, 65 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2019
    HBZ-ID HT020361004
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 E 139 order for loan Magazin

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  2. Article ; Online: Acupuncture for the treatment of vestibular migraine: a case report.

    Li, Mao / Xu, Jin

    Acupuncture in medicine : journal of the British Medical Acupuncture Society

    2024  , Page(s) 9645284231215800

    Language English
    Publishing date 2024-01-20
    Publishing country England
    Document type Letter
    ZDB-ID 1360533-1
    ISSN 1759-9873 ; 0964-5284
    ISSN (online) 1759-9873
    ISSN 0964-5284
    DOI 10.1177/09645284231215800
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Solid-Phase Electrosynthesis.

    Li, Mao / Li, Yongfang

    Accounts of chemical research

    2023  Volume 56, Issue 24, Page(s) 3694–3703

    Abstract: ConspectusThe significance of the new synthetic approach is that it can overcome the limitations of conventional methods and produce previously inaccessible polymer structures and materials. The solid-phase synthesis developed by Merrifield in 1964 is ... ...

    Abstract ConspectusThe significance of the new synthetic approach is that it can overcome the limitations of conventional methods and produce previously inaccessible polymer structures and materials. The solid-phase synthesis developed by Merrifield in 1964 is widely employed for the synthesis of biological molecules, such as peptides, nucleic acids, and oligosaccharides. Although the variety of iterative reactions available is theoretically implemented for most organic synthesis protocols, they are usually required to have high efficiency against sluggish reaction kinetics at the solid-liquid interface and process with protection and deprotection steps. Generally, unsatisfied reaction dynamics at the solid-liquid interface cannot statistically permit accurate and uniform polymer synthesis of sophisticated structures and functions within an acceptable time scale. To address this challenge, we propose the concept of solid-phase electrosynthesis, which simultaneously enables rapidly surface-initiated uniform electrosynthesis and unidirectional assembly of metallopolymers via kinetically accelerated and statistically allowed iterative growth. In particular, on a self-assembled monolayer (SAM) of the metal complex with electroactive unit A, the iterative monomer with two electroactive units A and B can be alternatively activated by oxidative and reductive potentials for A-A and B-B covalent couplings with the SAM, respectively. This enables topochemical one-by-one additions of the iterative monomers to end-on-oriented self-assembled molecules through alternative redox reactions. Each iterative step is purified by washing. Repeating the same iterative reaction enables further reaction of the unreactive sites on the SAMs and repairs the morphology defects, thereby ensuring the statistically allowed uniform synthesis and fabrication of polymer monolayers. The resulting monolayers exhibit subnanometer-uniform morphology over centimeter-sized areas with crystalline states and show thicknesses similar to theoretical molecular lengths. This demonstrates the unidirectional formation of polymer assemblies, providing a pathway for obtaining highly ordered formation of noncrystalline polymers. The length-controlled electrosynthesis of metallopolymers can be generalized for many types of organic ligands and metal species, enabling quantitative design of the composition and sequence-controlled metallopolymers with the precise relationships of structures and properties. Solid-phase electrosynthesis offers a unique approach to synthesize polymer structures and monolayers with enhanced functionality and superior physical properties, including physical density, modulus, and conductance. Through the utilization of precise and efficient iterative growth, this predictable electrosynthesis, coupled with optical and electrical monitoring, not only expands the scope of current synthetic chemistry but also paves a potential way for the automated generation of optoelectric molecular monolayers with large-area dimensional consistency and enhanced physical performance.
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1483291-4
    ISSN 1520-4898 ; 0001-4842
    ISSN (online) 1520-4898
    ISSN 0001-4842
    DOI 10.1021/acs.accounts.3c00620
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  4. Article ; Online: Assessment of college students' mental health status based on temporal perception and hybrid clustering algorithm under the impact of public health events.

    Li, Mao / Li, Fanfan

    PeerJ. Computer science

    2023  Volume 9, Page(s) e1586

    Abstract: The dynamic landscape of public health occurrences presents a formidable challenge to the emotional well-being of college students, necessitating a precise appraisal of their mental health (MH) status. A pivotal metric in this realm is the Mental Health ... ...

    Abstract The dynamic landscape of public health occurrences presents a formidable challenge to the emotional well-being of college students, necessitating a precise appraisal of their mental health (MH) status. A pivotal metric in this realm is the Mental Health Assessment Index, a prevalent gauge utilized to ascertain an individual's psychological well-being. However, prevailing indices predominantly stem from a physical vantage point, neglecting the intricate psychological dimensions. In pursuit of a judicious evaluation of college students' mental health within the crucible of public health vicissitudes, we have pioneered an innovative metric, underscored by temporal perception, in concert with a hybrid clustering algorithm. This augmentation stands poised to enrich the extant psychological assessment index framework. Our approach hinges on the transmutation of temporal perception into a quantifiable measure, harmoniously interwoven with established evaluative metrics, thereby forging a novel composite evaluation metric. This composite metric serves as the fulcrum upon which we have conceived a pioneering clustering algorithm, seamlessly fusing the fireworks algorithm with K-means clustering. The strategic integration of the fireworks algorithm addresses a noteworthy vulnerability inherent to K-means-its susceptibility to converging onto local optima. Empirical validation of our paradigm attests to its efficacy. The proposed hybrid clustering algorithm aptly captures the dynamic nuances characterizing college students' mental health trajectories. Across diverse assessment stages, our model consistently attains an accuracy threshold surpassing 90%, thus outshining existing evaluation techniques in both precision and simplicity. In summation, this innovative amalgamation presents a formidable stride toward an augmented understanding of college students' mental well-being during times of fluctuating public health dynamics.
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.1586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: C3-C3' and C6-C6' Oxidative Couplings of Carbazoles.

    Li, Mao

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2018  Volume 25, Issue 5, Page(s) 1142–1151

    Abstract: 9-Substituted carbazoles are widely used units in materials science, and their oxidative reactions have been utilized for the synthesis and characterization of polymers. Though the oxidative mechanism of carbazoles has been known for a few decades, ... ...

    Abstract 9-Substituted carbazoles are widely used units in materials science, and their oxidative reactions have been utilized for the synthesis and characterization of polymers. Though the oxidative mechanism of carbazoles has been known for a few decades, structural definition has remained difficult, because their polymers are generally insoluble with incomplete characterization and unknown dependence of the electrochemical potentials. The oxidative reactions of 9-substituted carbazoles should be carefully considered under specific oxidative conditions; otherwise, structure definitions could be wrong, because the IR and NMR spectra used previously cannot quantitatively analyze 3,3'-coupling and 6,6'-coupling of carbazoles. In this review, the best understanding of the C3-C3' and C6-C6' oxidative couplings of 9-substituted carbazoles is presented, and the benefit of these oxidative reactions from the viewpoints of electrochemical synthesis, film engineering, and the synthesis and processing of polymers is highlighted.
    Language English
    Publishing date 2018-11-19
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478547-x
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.201803246
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  6. Article ; Online: Responses of photosynthesis to NaCl in gametophytes of Acrostichum aureum.

    Li, Mao-Ping / Ong, Bee-Lian

    Physiologia plantarum

    2022  Volume 102, Issue 1, Page(s) 119–127

    Abstract: Gametophytes of Acrostichum aureum were cultured in 0.0 to 1.0% NaCl solutions or in NaCl-free solution and then transferred to 1.0% NaCl solution. Photosynthetic light-response curves, efficiency of the primary photochemical reaction, relative electron ... ...

    Abstract Gametophytes of Acrostichum aureum were cultured in 0.0 to 1.0% NaCl solutions or in NaCl-free solution and then transferred to 1.0% NaCl solution. Photosynthetic light-response curves, efficiency of the primary photochemical reaction, relative electron transport rate, and photochemical and non-photochemical quenching at steady state were determined by photosynthetic O
    Language English
    Publishing date 2022-03-09
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 2020837-6
    ISSN 1399-3054 ; 0031-9317
    ISSN (online) 1399-3054
    ISSN 0031-9317
    DOI 10.1034/j.1399-3054.1998.1020116.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Carcinoma within a lymphoepithelial cyst: a case report.

    Jiang, Hongjie / Li, Mao / Tang, Yueyang / Tang, Yaling

    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

    2023  Volume 41, Issue 2, Page(s) 237–242

    Abstract: Malignant transformation arising in benign lymphoepithelial cysts is a complex and rare occurrence, and related research is limited. This study presents a case of the malignant degeneration of lymphoepithelial cyst in parapharyngeal space. ... ...

    Abstract Malignant transformation arising in benign lymphoepithelial cysts is a complex and rare occurrence, and related research is limited. This study presents a case of the malignant degeneration of lymphoepithelial cyst in parapharyngeal space. Clinicopathological features and differential diagnosis are discussed with literature review to provide reference for clinical diagnosis and treatment management.
    MeSH term(s) Humans ; Carcinoma ; Diagnosis, Differential ; Cysts
    Language Chinese
    Publishing date 2023-04-14
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 1202342-5
    ISSN 2618-0456 ; 1000-1182
    ISSN (online) 2618-0456
    ISSN 1000-1182
    DOI 10.7518/hxkq.2023.2022395
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    Zs.A 4073: Show issues Location:
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  8. Article ; Online: Acupuncture for the treatment of constipation in Parkinson's disease: a case report.

    Wang, Wujun / Jiang, Lianyan / Feng, Xianrong / Li, Mao

    Acupuncture in medicine : journal of the British Medical Acupuncture Society

    2023  Volume 41, Issue 2, Page(s) 112–113

    MeSH term(s) Humans ; Parkinson Disease/complications ; Parkinson Disease/therapy ; Acupuncture Therapy/adverse effects ; Constipation/etiology ; Constipation/therapy
    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1360533-1
    ISSN 1759-9873 ; 0964-5284
    ISSN (online) 1759-9873
    ISSN 0964-5284
    DOI 10.1177/09645284221146200
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4628: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Preliminary application of artificial intelligence in the pathological diagnosis of periapical cysts

    HAO Yihang / HUANG Meichang / LI Mao / TANG Yaling / LIANG Xinhua

    口腔疾病防治, Vol 31, Iss 9, Pp 641-

    2023  Volume 646

    Abstract: Objective To study the effect of artificial intelligence in the pathological diagnosis of periapical cysts and to explore the application of artificial intelligence in the field of oral pathology. Methods Pathological images of eighty-seven periapical ... ...

    Abstract Objective To study the effect of artificial intelligence in the pathological diagnosis of periapical cysts and to explore the application of artificial intelligence in the field of oral pathology. Methods Pathological images of eighty-seven periapical cysts were selected as subjects to read, and a neural network with a U-net structure was constructed. The 87 HE images and labeled images of periapical cysts were divided into a training set (72 images) and a test set (15 images), which were used in the training model and test model, respectively. Finally, the target level index F1 score, pixel level index Dice coefficient and receiver operating characteristic (ROC) curve were used to evaluate the ability of the U-net model to recognize periapical cyst epithelium. Results The F1 score of the U-net network model for recognizing periapical cyst epithelium was 0.75, and the Dice index and the areas under the ROC curve were 0.685 and 0.878, respectively. Conclusion The U-net network model constructed by artificial intelligence has a good segmentation result in identifying periapical cyst epithelium, which can be preliminarily applied in the pathological diagnosis of periapical cysts and is expected to be gradually popularized in clinical practice after further verification with large samples.
    Keywords periapical cyst ， ; pathological diagnosis ， ; radiological diagnosis ， ; artificial intelligence ， ; oral pathology， ; u-net network， ; dice coefficient ， ; receiver operating characteristic curve， ; Medicine ; R
    Language Chinese
    Publishing date 2023-09-01T00:00:00Z
    Publisher Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Cost-Effective Calculation of Collective Electronic Excitations in Graphite Intercalated Compounds

    Pengfei Suo / Li Mao / Jing Shi / Hongxing Xu

    Nanomaterials, Vol 12, Iss 1746, p

    2022  Volume 1746

    Abstract: Graphite/graphene intercalation compounds with good and improving electrical transport properties, optical properties, magnetic properties and even superconductivity are widely used in battery, capacitors and so on. Computational simulation helps with ... ...

    Abstract Graphite/graphene intercalation compounds with good and improving electrical transport properties, optical properties, magnetic properties and even superconductivity are widely used in battery, capacitors and so on. Computational simulation helps with predicting important properties and exploring unknown functions, while it is restricted by limited computing resources and insufficient precision. Here, we present a cost-effective study on graphite/graphene intercalation compounds properties with sufficient precision. The calculation of electronic collective excitations in AA-stacking graphite based on the tight-binding model within the random phase approximation framework agrees quite well with previous experimental and calculation work, such as effects of doping level, interlayer distance, and interlayer hopping on 2D <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>π</mi></semantics></math> plasmon and 3D intraband plasmon modes. This cost-effective simulation method can be extended to other intercalation compounds with unlimited intercalation species.
    Keywords intercalation ; plasmon ; tight-binding model ; local-field effects ; Chemistry ; QD1-999
    Subject code 690
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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