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  1. Book ; Online: The Neural Basis of Human Prosocial Behavior

    Chen, Yefeng / Ye, Hang / Liu, Chao / Li, Qi

    2019  

    Keywords Science: general issues ; Psychology ; Neural Basis ; Prosocial Behavior ; neural mechanisms ; neural imaging ; Brain
    Size 1 electronic resource (161 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021229922
    ISBN 9782889632183 ; 2889632180
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: [Interpretation of the 2019 American Academy of Audiology "Clinical Cochlear Implantation Clinical Practice Guide": patient selection and indications].

    Li, Qi

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2021  Volume 35, Issue 6, Page(s) 491–494

    Abstract: In 2019, American Academy of Audiology published the clinical practice guideline for cochlear implant based on evidence-based methodology. The primary purposes of this guideline were to provide a set of statements, recommendations, and strategies for ... ...

    Abstract In 2019, American Academy of Audiology published the clinical practice guideline for cochlear implant based on evidence-based methodology. The primary purposes of this guideline were to provide a set of statements, recommendations, and strategies for cochlear implant. This paper aimed at interpreting the guideline with a focus on patient selection and indications sections. The determination of candidacy for a cochlear implant involves a series of tests, including audiometric testing, electrophysiology, fitting and verification of amplification, speech perception, and a solid understanding of the impact of hearing loss on educational, vocational, and psychosocial outcomes, as well as speech and language skills. The aspects of the pre-operative process for determining candidacy for a cochlear implant are described in this paper.
    MeSH term(s) Audiology ; Cochlear Implantation ; Cochlear Implants ; Hearing Loss/surgery ; Humans ; Patient Selection ; Speech Perception ; United States
    Language Chinese
    Publishing date 2021-07-14
    Publishing country China
    Document type Journal Article
    ISSN 2096-7993
    ISSN 2096-7993
    DOI 10.13201/j.issn.2096-7993.2021.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Genistein loaded by PRF improved bone healing in obese mice].

    Zhang, Xue-Bing / Li, Qi

    Shanghai kou qiang yi xue = Shanghai journal of stomatology

    2024  Volume 33, Issue 1, Page(s) 13–21

    Abstract: Purpose: To clarify the effect of genistein(GEN) on osteogenic differentiation and explore the effect of GEN loaded by platelet-rich fibrin (PRF) on the repair process of bone defects in obese mice.: Methods: In in vitro experiments, the effect of ... ...

    Abstract Purpose: To clarify the effect of genistein(GEN) on osteogenic differentiation and explore the effect of GEN loaded by platelet-rich fibrin (PRF) on the repair process of bone defects in obese mice.
    Methods: In in vitro experiments, the effect of GEN(0, 0.1, 1, 10, 50 μmol/L) on the proliferation of mouse embryonic osteoblast precursor cells (MC3T3-E1) was determined by CCK 8. Alkaline phosphatase(ALP) staining and quantitative detection of ALP activity were performed to determine the changes of ALP activity in cells; RNA and protein expression levels of ALP, osteopontin (OPN) and osteocalcin (OCN) were detected by quantitative real-time PCR(qRT-PCR) and Western blot. Alizarin red staining was used to define the effect of GEN on mineralization of MC3T3-E1. To verify the feasibility of the PRF drug loading, the ultrastructure of PRF was subsequently observed under SEM. In in vivo experiments, obese C57 mouse models were established by high-fat diet feeding. On this basis, skull defect models with a diameter of 2.8 mm were established, and the prepared GEN/PRF complexes were placed into the bone defect area. The effects of GEN on skull defect repair in obese mice were evaluated by Micro-CT scanning and hematoxylin-eosin(H-E) staining. Statistical analysis was performed with GraphPad Prism 5.0 software package.
    Results: CCK 8 results showed that 0.1, 1 μmol/L GEN promoted cell proliferation within 7 days(P<0.05); 10 μmol/L GEN had no significant effect on the process of cell proliferation. From the second day, 50 μmol/L GEN significantly inhibited cell growth and showed cytotoxicity(P<0.05). These two concentrations had similar effects in promoting cellular osteogenic differentiation. SEM results showed that PRF presented a 3-dimensional network structure, providing space for loading drug molecules. In in vivo experiments, the body weight of mice in the high-fat diet (HFD) group was 27.7% greater than that in the normal diet group(P<0.05) and had abnormal glucose tolerance (P<0.05). Micro-CT showed that compared with the normal diet group, the number of bone trabeculae in the femur of obese mice was decreased(P<0.05), the distance between bone trabeculae was widened(P<0.05), and the bone density was decreased (P<0.05). In addition, GEN (0.1, 1.0 μmol/L) loaded by PRF increased bone volume fraction in the skull of obese mice (P<0.05). H-E results showed that GEN/PRF promoted the healing of the bone defects.
    Conclusions: GEN promotes osteogenic differentiation of MC3T3-E1, and it can effectively accelerate the healing of cranial bone defects after loading with PRF in obese mice.
    MeSH term(s) Animals ; Mice ; Osteogenesis/genetics ; Genistein/pharmacology ; Mice, Obese ; Platelet-Rich Fibrin ; Sincalide/pharmacology ; Cell Differentiation/genetics ; Osteoblasts
    Chemical Substances Genistein (DH2M523P0H) ; Sincalide (M03GIQ7Z6P)
    Language Chinese
    Publishing date 2024-04-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2269714-7
    ISSN 1006-7248
    ISSN 1006-7248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Trend of global oil supply chain change:Comparison based on physical and virtual oil trade

    LI Qi, ZHENG Minggui, ZENG Jianlin

    Ziyuan Kexue, Vol 45, Iss 8, Pp 1497-

    2023  Volume 1514

    Abstract: Objective] This study analyzed the trend of change of global oil supply chain from the perspective of comparing physical and virtual oil trade, so as to reveal the important role of virtual oil. [Methods] Based on the traditional multi-regional input- ... ...

    Abstract [Objective] This study analyzed the trend of change of global oil supply chain from the perspective of comparing physical and virtual oil trade, so as to reveal the important role of virtual oil. [Methods] Based on the traditional multi-regional input-output table, this study constructed a multi-regional input-output model of oil, calculated virtual oil in oil trade from 2000 to 2016, and comprehensively examined the main countries of oil production, consumption, and trade and their flow relations from the dual perspectives of physical and virtual oil. The heterogeneity of oil trade in 189 countries (regions) and 26 sectors was discussed by distinguishing intermediate and final product. The trade balance and external dependence of physical and virtual oil were further analyzed, and the global implicit oil demand before 2030 was predicted according to the accelerated energy transformation scenario. [Results] The study found that: (1) Virtual oil production accounted for more than one-third of the total global oil production. Virtual oil production and consumption are mainly concentrated in countries (regions) with higher economic development levels, while physical oil production and consumption are mainly distributed in countries (regions) with abundant oil resources; (2) The total amount of virtual oil trade flowing to countries (regions) with higher levels of industrialization and economic development is greater than the corresponding amount of physical oil trade. The virtual oil trade played a positive role in promoting the global oil trade balance and supply security; (3) The pattern of oil trade between final products and intermediate products is opposite, and the exporting country (region) in intermediate product trade is transformed into the importing country (region) in final product trade; (4) From 2017 to 2030, the oil demand of most developed countries showed a significant downward trend, and the implied oil demand steadily decreased after reaching its peak in different years, maintaining around ...
    Keywords |oil supply chain|virtual oil|trade balance|physical trade|multi-region input and output method|energy transition ; Environmental sciences ; GE1-350 ; Biology (General) ; QH301-705.5
    Subject code 381
    Language Chinese
    Publishing date 2023-08-01T00:00:00Z
    Publisher Science Press, PR China
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Application of acquiring region of interest based on the YOLOv5 model in terahertz digital holography.

    Cheng, Keyang / Li, Qi

    Applied optics

    2023  Volume 62, Issue 14, Page(s) 3589–3597

    Abstract: The imaging process of terahertz in-line digital holography is susceptible to environmental interference, and it is difficult to obtain high-quality images and image segmentation results. The challenge can be better handled by using the region of ... ...

    Abstract The imaging process of terahertz in-line digital holography is susceptible to environmental interference, and it is difficult to obtain high-quality images and image segmentation results. The challenge can be better handled by using the region of interest (ROI) condition to improve the image quality of the object region and reduce the interference of peripheral noise. In this paper, for two-dimensional 2.52 THz in-line digital holography, a method to add a variety of real backgrounds in the simulation scene is proposed, and through this method, a sufficient amount of close-to-real-scene images are produced to train the YOLOv5 model. The object ROI is extracted by the YOLOv5 model (YOLOv5-ROI). Based on the region, a new, to the best of our knowledge, support-domain-constrained phase retrieval algorithm (YOLOv5-ROI-SPRA) and an image segmentation method combined with the Otsu method (YOLOv5-ROI-Otsu) are proposed, respectively. The better results show that the expected purpose is achieved.
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.484993
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mitf involved in shell pigmentation by activating tyrosinase-mediated melanin synthesis in Pacific oyster (Crassostrea gigas).

    Zhu, Yijing / Li, Qi

    Gene

    2023  Volume 897, Page(s) 148086

    Abstract: Pigmentation is frequently observed in the molluscan shells, whereas the molecular regulation about these shell pigments formation is not clear. The microphthalmia-associated transcription factor (Mitf) is an important transactivator in melanin synthesis ...

    Abstract Pigmentation is frequently observed in the molluscan shells, whereas the molecular regulation about these shell pigments formation is not clear. The microphthalmia-associated transcription factor (Mitf) is an important transactivator in melanin synthesis in vertebrates. Here, the Mitf containing a highly conserved basic helix-loop-helixleucine zipper (bHLH-LZ) domain was identified in an economically important marine bivalve Pacific oyster Crassostrea gigas. The Mitf was found to widespread tissue distribution and the expression was higher in the marginal mantle than in the central mantle. Particularly, the expression level of Mitf was high in black shell color oysters compared with white shell oysters. After injecting siRNA, the expression of Mitf decreased significantly, and the efficiency of RNA interference reached 53%. Besides, knockdown Mitf obviously decreased expression of tyrosinase family genes and tyrosinase activity of mantles, indicating a potential regulatory relationship between Mitf and Tyr or Typs. Simultaneously, there was a sharply reduce in the number of the melanosomes in the outer fold of mantle by silencing of Mitf. Luciferase assays in cell culture further verified that Mitf was involved in transcriptional regulation of Typ-2 and Typ-3 genes through binding to their specific promoter regions. These data argue that Mitf is involved in shell pigmentation through activating tyrosinase-mediated melanin synthesis in C. gigas.
    MeSH term(s) Animals ; Crassostrea/genetics ; Crassostrea/metabolism ; Melanins ; Microphthalmia-Associated Transcription Factor/genetics ; Monophenol Monooxygenase/genetics ; Pigmentation/genetics
    Chemical Substances Melanins ; Microphthalmia-Associated Transcription Factor ; Monophenol Monooxygenase (EC 1.14.18.1)
    Language English
    Publishing date 2023-12-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2023.148086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Sinicization Innovation of Marxist Humanistic Theory in Colleges and Universities Under the Background of Innovative Thinking.

    Li, Qi / Ma, Yan

    Psychology research and behavior management

    2023  Volume 16, Page(s) 1897–1909

    Abstract: Introduction: It is urgent to explore and solve the problems in China's current Marxist psychological education. The main goal of the research is to promote the sinicization innovation of Marxist humanistic theory in colleges and universities.: ... ...

    Abstract Introduction: It is urgent to explore and solve the problems in China's current Marxist psychological education. The main goal of the research is to promote the sinicization innovation of Marxist humanistic theory in colleges and universities.
    Methods: Combined with Marxist humanist theory, this paper designs a science, technology, engineering, and mathematics teaching mode for cultivating innovative thinking in an attempt to change the way college students cultivate innovative thinking. The research method is to discuss the status, problems, causes, and countermeasures of the sinicization innovation of Marxist humanistic theory in colleges and universities through literature research, logical analysis, and empirical research.
    Results: The progress and existing problems of college students' current psychological education logic are summarized based on empirical research. The research results show that the innovation of Marxist humanistic theory in colleges and universities needs to be innovated in terms of theory, method, content, and form and integrated into the development needs and innovation requirements of contemporary Chinese society. The countermeasures implemented include promoting the intersectionality, interdisciplinarity, and innovation of Marxist humanistic theory research in colleges and universities, strengthening the close integration of Marxist humanistic theory education and practice in colleges and universities, and enhancing the effectiveness and orientation of Marxist humanistic theory education in colleges and universities.
    Discussion: In the context of innovative thinking, the effectiveness of psychological logic education should be further improved through innovative research on the sinicization of Marxist humanistic theory in colleges and universities.
    Language English
    Publishing date 2023-05-24
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2495093-2
    ISSN 1179-1578
    ISSN 1179-1578
    DOI 10.2147/PRBM.S405168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comparative Transcriptome and WGCNA Analysis Reveal Molecular Responses to Salinity Change in Larvae of the Iwagaki Oyster Crassostrea Nippona.

    Gong, Jianwen / Li, Qi

    Marine biotechnology (New York, N.Y.)

    2023  Volume 25, Issue 6, Page(s) 1031–1042

    Abstract: The Iwagaki oyster Crassostrea nippona is an important aquaculture species with significant potential for large-scale oyster farming. It is susceptible to the fluctuated salinity in the coastal area. In this study, we compared the transcriptome of ... ...

    Abstract The Iwagaki oyster Crassostrea nippona is an important aquaculture species with significant potential for large-scale oyster farming. It is susceptible to the fluctuated salinity in the coastal area. In this study, we compared the transcriptome of Crassostrea nippona larvae under variant conditions with low-salinity stress (28, 20, 15, 10, and 5 practical salinity units (psu)) for 24 h. KEGG enrichment analysis of differentially expressed genes (DEGs) from pairwise comparisons identified several free amino acid metabolism pathway (taurine and hypotaurine, arginine and proline, glycine, and beta-alanine) contributing to the salinity change adaptation and activated "lysosome" and "apoptosis" pathway in response to the low-salinity stress (10 and 5 psu). Trend analysis revealed sustained upregulation of transmembrane transport-related genes (such as SLC family) and downregulation of ribosomal protein synthesis genes faced with decreasing salinities. In addition, 9 biomarkers in response to low-salinity stress were identified through weighted gene co-expression network analysis (WGCNA) and validated by qRT-PCR. Our transcriptome analysis provides a comprehensive view of the molecular mechanisms and regulatory networks underlying the adaptive responses of oyster larvae to hypo-salinity conditions. These findings contribute to our understanding of the complex biological processes involved in oyster resilience and adaptation to changing environmental conditions.
    MeSH term(s) Animals ; Transcriptome ; Crassostrea/metabolism ; Salinity ; Larva/genetics ; Gene Expression Profiling
    Language English
    Publishing date 2023-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1479877-3
    ISSN 1436-2236 ; 1436-2228
    ISSN (online) 1436-2236
    ISSN 1436-2228
    DOI 10.1007/s10126-023-10257-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Comparative Transcriptome Analysis Reveals the Role of Ribosome Reduction in Impeding Oogenesis in Female Triploid Crassostrea Gigas.

    Yang, Qiong / Yu, Hong / Li, Qi

    Marine biotechnology (New York, N.Y.)

    2024  Volume 26, Issue 1, Page(s) 125–135

    Abstract: The fecundity of triploid female Crassostrea gigas exhibited significant variation and was lower compared to diploid individuals. Previous studies categorized mature stage triploid female C. gigas into two groups: female α, characterized by a high number ...

    Abstract The fecundity of triploid female Crassostrea gigas exhibited significant variation and was lower compared to diploid individuals. Previous studies categorized mature stage triploid female C. gigas into two groups: female α, characterized by a high number of oocytes, and female β, displaying few or no oocytes. To investigate the molecular mechanisms underlying irregular oogenesis and fecundity differences in triploid C. gigas, we performed a comparative analysis of gonad transcriptomes at different stages of gonadal development, including female α, female β, and diploids. During early oogenesis, functional enrichment analysis between female diploids and putative female β triploids revealed differently expressed genes (DEGs) in the ribosome and ribosome biogenesis pathways. Expression levels of DEGs in these pathways were significantly decreased in the putative female β triploid, suggesting a potential role of reduced ribosome levels in obstructing triploid oogenesis. Moreover, to identify regulatory pathways in gonad development, female oysters at the early and mature stages were compared. The DNA repair and recombination proteins pathways were enriched in female diploids and female α triploids but absent in female β triploids. Overall, we propose that decreased ribosome biogenesis in female triploids hinders the differentiation of germ stem cells, leading to the formation of a large number of abnormal germ cells and ultimately resulting in reduced fecundity. The variation in fertility among triploids appeared to be related to the degree of DNA damage repair during female gonad development. This study offers valuable insights into the oogenesis process in female triploid C. gigas.
    MeSH term(s) Animals ; Female ; Humans ; Triploidy ; Crassostrea/genetics ; Transcriptome ; Oogenesis/genetics ; Gene Expression Profiling ; Ribosomes/genetics
    Language English
    Publishing date 2024-01-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1479877-3
    ISSN 1436-2236 ; 1436-2228
    ISSN (online) 1436-2236
    ISSN 1436-2228
    DOI 10.1007/s10126-024-10283-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Analysis of nasal flora composition in children with perennial allergic rhinitis].

    Shen, Xiaofei / Teng, Zhipan / Li, Qi / Yu, Zhenkun

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2024  Volume 38, Issue 2, Page(s) 127–132;139

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Child ; Humans ; Rhinitis, Allergic, Perennial ; Rhinitis, Allergic/diagnosis
    Language Chinese
    Publishing date 2024-02-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 2096-7993
    ISSN 2096-7993
    DOI 10.13201/j.issn.2096-7993.2024.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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