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Article: [Attach importance to the orderly development of different corneal transplant procedures].

Shi, W Y / Li, S X

Zhonghua yan ke za zhi] Chinese journal of ophthalmology

2024 Volume 60, Issue 2, Page(s) 109–112

Abstract: There are various surgical methods for corneal transplantation, each requiring precise treatment tailored to the characteristics and different layers of corneal opacity or lesions. These layers include the corneal epithelium, stroma (lamellar), and ... ...

Abstract	There are various surgical methods for corneal transplantation, each requiring precise treatment tailored to the characteristics and different layers of corneal opacity or lesions. These layers include the corneal epithelium, stroma (lamellar), and corneal endothelium, with options for full-thickness (penetrating) corneal transplantation or artificial corneal transplantation. However, a current issue in clinical practice is that, regardless of the degree of corneal disease, the availability of corresponding eye bank support, or surgical conditions, classic penetrating (full-thickness) corneal transplantation is universally performed. Alternatively, there is a trend toward adopting technically demanding procedures such as endothelial transplantation and artificial corneal transplantation. This trend has led to increased postoperative complications and the wastage of corneal donor materials. Choosing the appropriate corneal transplant procedure can offer advantages such as preserving more healthy corneal tissue, conserving corneal donors, facilitating rapid vision recovery, and minimizing the risk of immune rejection. Corneologists need to master the indications for various corneal transplant surgeries and systematically perform different corneal transplant procedures based on the surgeon's skills, hospital conditions, and eye bank conditions. This approach aims to enhance the success rate of the surgery.
MeSH term(s)	Humans ; Corneal Transplantation ; Cornea/surgery ; Corneal Diseases/surgery ; Endothelium, Corneal ; Eye Banks
Language	Chinese
Publishing date	2024-01-30
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604574-1
ISSN	0412-4081
ISSN	0412-4081
DOI	10.3760/cma.j.cn112142-20231113-00227
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Article: [Dissection borders of laparoscopic lower mediastinal lymphadenectomy for adenocarcinoma of esophagogastric junction and the quality control].

Li, S X / Li, Z Y

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

2022 Volume 25, Issue 2, Page(s) 120–123

Abstract: The lower mediastinal lymphadenectomy is indicated for adenocarcinoma of esophagogastric junction (AEG), while the laparoscopic procedure shows some advantages. According to previous studies and results of IDEAL phase 2a study in our institute, the ... ...

Abstract	The lower mediastinal lymphadenectomy is indicated for adenocarcinoma of esophagogastric junction (AEG), while the laparoscopic procedure shows some advantages. According to previous studies and results of IDEAL phase 2a study in our institute, the following structures are recommended as the dissection borders: the upper (cranial) is inferior wall of pericardium and pulmonary ligament; the lower (caudal) is diaphragm hiatus (esophagogastric junction); the front (ventral) is anterior inferior wall of pericardium and diaphragm; the back (dorsal) is anterior wall of aorta; the lateral is mediastinal pleura. The standard of quality control is still under investigation.
MeSH term(s)	Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophagogastric Junction/pathology ; Esophagogastric Junction/surgery ; Humans ; Laparoscopy/methods ; Lymph Node Excision/methods ; Quality Control ; Retrospective Studies ; Stomach Neoplasms/surgery
Language	Chinese
Publishing date	2022-02-17
Publishing country	China
Document type	Journal Article
ISSN	1671-0274
ISSN	1671-0274
DOI	10.3760/cma.j.cn441530-20211221-00518
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Article: [Surveys on diagnosis and treatment of esophagogastric junction adenocarcinoma by the Chinese Laparoscopic Gastrointestinal Surgery Study Group-10 Research Team].

Li, S X / Li, Z Y / Ji, J F

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

2023 Volume 26, Issue 8, Page(s) 773–779

Abstract: Objective: ...

Abstract	Objective:
Language	Chinese
Publishing date	2023-08-14
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	1671-0274
ISSN	1671-0274
DOI	10.3760/cma.j.cn441530-20221123-00490
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Article: [Intraoperative optical coherence tomography guided precise corneal suture in the treatment of acute keratoconus].

Li, S X / Wang, N / Su, M / Jiang, X Y / Gao, H / Shi, W Y

Zhonghua yan ke za zhi] Chinese journal of ophthalmology

2024 Volume 60, Issue 2, Page(s) 147–155

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Humans ; Male ; Female ; Adolescent ; Young Adult ; Adult ; Child ; Keratoconus/surgery ; Tomography, Optical Coherence/methods ; Corneal Edema/surgery ; Cornea/surgery ; Corneal Transplantation ; Sutures
Language	Chinese
Publishing date	2024-01-30
Publishing country	China
Document type	Controlled Clinical Trial ; English Abstract ; Journal Article
ZDB-ID	604574-1
ISSN	0412-4081
ISSN	0412-4081
DOI	10.3760/cma.j.cn112142-20231016-00145
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Article: [Studies on clinicopathological features of duodenal-type follicular lymphoma of 18 patients].

Du, Y R / Li, J / Li, S X / Guan, C Y / Li, H L / Gao, Z F / Li, X / Dong, G H

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

2024 Volume 45, Issue 1, Page(s) 94–97

Abstract: To investigate the clinical and pathological characteristics of duodenal-type follicular lymphoma (D-FL), and to deepen the understanding of Duodenal-type follicular lymphoma. The clinical symptoms, endoscopic features, pathologic features, ... ...

Abstract	To investigate the clinical and pathological characteristics of duodenal-type follicular lymphoma (D-FL), and to deepen the understanding of Duodenal-type follicular lymphoma. The clinical symptoms, endoscopic features, pathologic features, immunophenotype, molecular pathological features and treatment follow-up of 18 D-FL patients diagnosed in Department of Pathology, Beijing Tiantan Hospital affiliated to Capital Medical University between January 2020 and July 2023 were summarized. A total of 18 patients with D-FL were included, including 10 males and 8 females. The median age was 49 (32-69) years respectively. Most of the patients were found during gastroenteroscopy or presented with the common gastrointestinal symptoms of stomach pain, acid reflux, vomiting and diarrhea. Most endoscopic findings were multiple small gray and white polyposis. In the pathological morphology, the mucous layer and submucous layer showed lymphoid follicular structures with full and strained follicles. The immunophenotype showed that the tumor cells strongly expressed CD20 and BCL2 and had low proliferation activity. Immunoglobulin clonal analysis of 1 case showed IgK monoclonal rearrangement (1/1). FISH showed 1 case of BCL2 gene rearrangement (1/3). All patients did not receive targeted chemotherapy and adopted a wait-and-see strategy. Median follow-up was 12 (2-34) months. This study shows that D-FL is an indolent lymphoma, which tends to occur in the duodenum and has a good prognosis.
MeSH term(s)	Male ; Female ; Humans ; Middle Aged ; Lymphoma, Follicular/drug therapy ; Proto-Oncogene Proteins c-bcl-2
Chemical Substances	Proto-Oncogene Proteins c-bcl-2
Language	Chinese
Publishing date	2024-03-25
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2997162-7
ISSN	0253-2727 ; 0253-2727
ISSN (online)	0253-2727
ISSN	0253-2727
DOI	10.3760/cma.j.cn121090-20230915-00125
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Article: Application of Automatic Nucleic Acid Extractor Combined with Vacuum Concentrator in Forensic Science.

Li, S X / Shen, J J / Cao, P J / Li, Z C

Fa yi xue za zhi

2021 Volume 37, Issue 2, Page(s) 220–224

Abstract: Abstract: Objective To explore the application value of automatic nucleic acid extractor combined with vacuum concentrator in forensic DNA extraction. Methods Gradient samples of human peripheral venous blood were collected at 40, 80, 120, 160, 200, 240, ...

Abstract	Abstract: Objective To explore the application value of automatic nucleic acid extractor combined with vacuum concentrator in forensic DNA extraction. Methods Gradient samples of human peripheral venous blood were collected at 40, 80, 120, 160, 200, 240, 280 and 320 fold dilution. The samples of each gradient were treated with no inhibitor, black oil, rust, fruit acid, tin foil and indigo, respectively. The automatic nucleic acid extractor was used for DNA purification and extraction of the above samples. The extracted DNA eluent （6 μL） was taken for amplification directly, and the rest was concentrated by vacuum concentrator. DNA was amplified and examined using the Investigator 26plex QS kit before and after concentration. Results Only gradient samples treated with fruit acid obtained complete STR typing results at 40 fold dilution. The other 5 methods obtained complete STR typing results at 40-160 fold dilution. The results of STR typing after DNA concentration showed that the average peak height and detection rates of gene loci both increased to a certain extent, but the effect was not obvious. Conclusion The automatic nucleic acid extractor has an efficient inhibitor removal ability and high extracting efficiency of DNA. The vacuum concentrator can concentrate DNA samples to a certain extent. Combining the automatic nucleic acid extractor with the vacuum concentrator can improve the examination success rate of forensic materials.
MeSH term(s)	DNA/genetics ; DNA Fingerprinting ; Humans ; Microsatellite Repeats ; Nucleic Acids ; Vacuum
Chemical Substances	Nucleic Acids ; DNA (9007-49-2)
Language	Chinese
Publishing date	2021-06-17
Publishing country	China
Document type	Journal Article
ISSN	1004-5619
ISSN	1004-5619
DOI	10.12116/j.issn.1004-5619.2020.500604
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Article: [The 496th case:recurrent syncope for 8 years].

Tang, W T / You, Y / Li, S X / Zhang, S

Zhonghua nei ke za zhi

2021 Volume 61, Issue 6, Page(s) 708–710

Abstract: A 25-year-old women was admitted to the department of Neurology in Affiliated 2nd Hospital of Hainan Medical University due to recurrent syncope for 8 years and return for 2 months. She had multiple episodes of syncope at onset. She presented with the ... ...

Abstract	A 25-year-old women was admitted to the department of Neurology in Affiliated 2nd Hospital of Hainan Medical University due to recurrent syncope for 8 years and return for 2 months. She had multiple episodes of syncope at onset. She presented with the feeling of weakness in both lower limbs, and fatigue in the past year. She experienced pain in the waist and limbs joint in recent three months. Physical examination showed joint hyperactivity in metacarpophalangeal joints of both upper limbs, increased skin elasticity. Active-standing transcranial Doppler (TCD) test showed that the average heart rate (HR) and the average middle cerebral artery (MCA) blood flow velocity in the supine position were 79 beats/min and 62 cm/s, respectively; while the average HR and the average MCA blood flow velocity in the standing position were 126 beats/min, 47 cm/s. Meanwhile,the blood pressure was normal during the test of supine-to-standing TCD. Genetic testing indicated LDB3 transgenation. The patient was diagnosed as postural tachycardia syndrome (joint-hypermobility-related), Ehlers-Danlos syndrome, and relieved by fluid infusion and rehabilitation therapy.
MeSH term(s)	Adult ; Blood Flow Velocity ; Blood Pressure ; Female ; Humans ; Middle Cerebral Artery/diagnostic imaging ; Syncope ; Ultrasonography, Doppler, Transcranial
Language	Chinese
Publishing date	2021-11-03
Publishing country	China
Document type	Journal Article
ZDB-ID	754223-9
ISSN	0578-1426
ISSN	0578-1426
DOI	10.3760/cma.j.cn112138-20210607-00403
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Article: [The relationship between homocysteine, coagulation dysfunction and breast cancer risk].

Liu, Z H / Yan, W / Li, F X / Li, S X / Liu, J T

Zhonghua zhong liu za zhi [Chinese journal of oncology

2022 Volume 44, Issue 6, Page(s) 562–569

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Blood Coagulation Disorders ; Breast Neoplasms ; Female ; Fibrinogen/metabolism ; Homocysteine ; Humans ; Lymphatic Metastasis ; Prothrombin Time
Chemical Substances	Homocysteine (0LVT1QZ0BA) ; Fibrinogen (9001-32-5)
Language	Chinese
Publishing date	2022-06-27
Publishing country	China
Document type	Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
DOI	10.3760/cma.j.cn112152-20200709-00633
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Article ; Online: Effect of intravenous thrombolysis in acute ischemic stroke patients with cerebral microbleeds and analysis of risk factors for hemorrhagic transformation.

Lei, Y-S / Li, H / Lei, J-Y / Li, S-X / Li, D-F

European review for medical and pharmacological sciences

2022 Volume 26, Issue 3, Page(s) 779–786

Abstract: Objective: To investigate the safety and efficacy of intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) in patients with acute ischemic stroke (AIS) and cerebral microbleeds (CMBs) and analyze the risk factors for hemorrhagic ...

Abstract	Objective: To investigate the safety and efficacy of intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) in patients with acute ischemic stroke (AIS) and cerebral microbleeds (CMBs) and analyze the risk factors for hemorrhagic transformation (HT). Patients and methods: The clinical data of 220 patients with CMB within the first 4.5 h after the onset of acute ischemic stroke treated in our hospital from September 2018 to December 2019 were retrospectively analyzed. Then, these patients were evenly assigned into two groups based on whether the intravenous thrombolysis with rt-PA was adopted or not. Next, the neurological deficit was scored using the National Institute of Health stroke scale (NIHSS) before and after treatment, the modified Rankin scale (mRs) score of patients was recorded at 90 d after treatment, and the incidence rate and death rate of intracranial hemorrhage (ICH) after treatment were recorded and evaluated. Additionally, the univariate and logistic regression analyses were employed for the risk factors for HT in patients after thrombolysis. Results: The NIHSS score declined to (7.08±3.75) points and (7.83±4.22) points at 24 h after treatment and (3.67±3.63) points and (4.92±3.87) points at 7 d after treatment, respectively, in Thrombolysis group and Control group, which were significantly lower than those before treatment (p<0.05). The NIHSS score displayed no statistically significant difference between the two groups at 24 h after treatment (p=0.165), whereas it was markedly lower in Thrombolysis group than that in Control group at 7 d after treatment (p=0.015). At 90 d after treatment, there were 98 (89.1%) and 79 (71.8%) cases of good prognosis in Thrombolysis group and Control group, respectively, and the difference was statistically significant between the two groups (p=0.002). Besides, the number of patients with SICH and aSICH was 3 and 2 (2.7% vs. 1.8%, p=0.651) and 9 and 4 (8.2% vs. 3.6%, p=0.152) in Thrombolysis group and Control group, respectively, and the number of deaths was 7 and 5 (6.4% vs. 4.5%, p=0.553) in the two groups, showing no statistically significant difference. The results of univariate and multivariate analyses revealed that the time from stroke onset to thrombolysis, baseline NIHSS score, and history of atrial fibrillation were independent risk factors affecting the HT of patients undergoing intravenous thrombolysis [odds ratio (OR) =1.330, 95% confidence interval (95% CI) =1.079-1.851, p=0.019; OR=1.592, 95% CI=1.025-2.767, p=0.010; OR=2.428, 95% CI=1.814-3.643, p=0.016]. Conclusions: Compared with those undergoing no intravenous thrombolysis with rt-PA, patients with acute ischemic stroke and CMB who received intravenous thrombolysis with rt-PA exhibit significantly improved short-term neurological function recovery and long-term prognosis, but the incidence and mortality rates of ICH have no statistically significant differences. Moreover, the time from stroke onset to thrombolysis, baseline NIHSS score, and history of atrial fibrillation are independent risk factors affecting the HT of patients treated with intravenous thrombolysis.
MeSH term(s)	Brain Ischemia/complications ; Brain Ischemia/drug therapy ; Cerebral Hemorrhage/drug therapy ; Cerebral Hemorrhage/etiology ; Fibrinolytic Agents/adverse effects ; Humans ; Ischemic Stroke/drug therapy ; Retrospective Studies ; Risk Factors ; Stroke/complications ; Thrombolytic Therapy/adverse effects ; Thrombolytic Therapy/methods ; Tissue Plasminogen Activator/therapeutic use ; Treatment Outcome
Chemical Substances	Fibrinolytic Agents ; Tissue Plasminogen Activator (EC 3.4.21.68)
Language	English
Publishing date	2022-02-18
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_202202_27986
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Article: [Acute myeloid leukemia with increased eosinophils and PDGFRβ mutation in one case].

Guo, X / Li, S X

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

2017 Volume 38, Issue 7, Page(s) 596

Language	Chinese
Publishing date	2017-08-12
Publishing country	China
Document type	Journal Article
ISSN	0253-2727
ISSN	0253-2727
DOI	10.3760/cma.j.issn.0253-2727.2017.07.008
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