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  1. Article ; Online: Defining the cell of origin for diffuse midline gliomas.

    Li, Xiao-Nan

    Nature genetics

    2022  Volume 54, Issue 12, Page(s) 1770–1771

    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1108734-1
    ISSN 1546-1718 ; 1061-4036
    ISSN (online) 1546-1718
    ISSN 1061-4036
    DOI 10.1038/s41588-022-01231-8
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  2. Article ; Online: Zinc tungstate encapsulated into a scarce Zn(II)-viologen framework with photochromic, electrochromic and chemochromic properties.

    Huang, Li / Li, Xiao-Nan / Shen, Yuan / Song, Run-Hong / Cui, Wen-Bo / Zhang, Hong

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 11, Page(s) 5192–5201

    Abstract: Smart chromic materials reacting to physicochemical stimuli are widely applied in optical switches, smart windows, and chemical sensors. Currently, most materials only respond to a single stimulus, but those that respond to multiple external stimuli are ... ...

    Abstract Smart chromic materials reacting to physicochemical stimuli are widely applied in optical switches, smart windows, and chemical sensors. Currently, most materials only respond to a single stimulus, but those that respond to multiple external stimuli are still in the minority. Herein, we report a novel porous zinc tungstate@metaloxoviologen framework [Zn
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt03647b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical study of suture anchors in the treatment of radial head fractures.

    Li, Xiao-Nan / Li, Yuan-Shen / Chen, Jun-Lin / Li, Qing-Shan / Suo, Yan-Hui

    BMC musculoskeletal disorders

    2023  Volume 24, Issue 1, Page(s) 117

    Abstract: Background: This study aimed to analyze and study the clinical effect of suture anchors in the treatment of radial head fractures (RHFs).: Methods: A total of 11 patients (five male and six female) with RHFs who were treated from March 2016 to June ... ...

    Abstract Background: This study aimed to analyze and study the clinical effect of suture anchors in the treatment of radial head fractures (RHFs).
    Methods: A total of 11 patients (five male and six female) with RHFs who were treated from March 2016 to June 2021 were included in this study. They were 17-61 (average 38.5) years old. In terms of the Johnston-Mason classification, two cases were type II, seven cases were type III, and two cases were type IV. All patients were treated with open reduction and anchor internal fixation.
    Results: All 11 patients were followed up, all incisions healed by first intention, and the duration of follow-up was 14-20 months. The average operation time was 40 ± 15 min. The clinical healing time was 4-6 (average 5) weeks. No patients had any complications, such as traumatic arthritis, malunion, nerve injury, joint stiffness, or incision infection. The clinical effects were evaluated according to the Mayo Elbow Performance Score. The scores of all 11 cases were 90-95, all excellent.
    Conclusion: The application of suture anchor internal fixation in the treatment of RHFs has the advantages of accurate reduction, no need for a secondary operation to remove the fixation materials, less trauma, fewer complications, good fracture healing, and good recovery of elbow extension, flexion, and rotation functions.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Suture Anchors ; Treatment Outcome ; Radial Head and Neck Fractures ; Radius Fractures/diagnostic imaging ; Radius Fractures/surgery ; Radius Fractures/etiology ; Elbow Joint/diagnostic imaging ; Elbow Joint/surgery ; Fracture Fixation, Internal/adverse effects ; Range of Motion, Articular/physiology ; Retrospective Studies
    Language English
    Publishing date 2023-02-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-023-06188-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Diagnosis and genetic analysis of a case with mandibuloacral dysplasia type B due to compound heterozygous mutations of the

    Wu, Dan-Dan / Li, Rong / Li, Xiao-Nan / Liu, Qian-Qi / Dou, Li-Hua

    Yi chuan = Hereditas

    2023  Volume 44, Issue 12, Page(s) 1167–1174

    Abstract: Mandibuloacral dysplasia (MAD) is a rare autosomal recessive disorder, mainly caused by pathogenic variants of ... ...

    Abstract Mandibuloacral dysplasia (MAD) is a rare autosomal recessive disorder, mainly caused by pathogenic variants of the
    MeSH term(s) Humans ; Metalloendopeptidases/genetics ; Lamin Type A/genetics ; Mutation ; Lipodystrophy/genetics ; Phenotype ; Membrane Proteins/genetics
    Chemical Substances Metalloendopeptidases (EC 3.4.24.-) ; Lamin Type A ; ZMPSTE24 protein, human (EC 3.4.24.84) ; Membrane Proteins
    Language English
    Publishing date 2023-03-16
    Publishing country China
    Document type Case Reports ; Journal Article
    ISSN 0253-9772
    ISSN 0253-9772
    DOI 10.16288/j.yczz.22-117
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  5. Article: 注意缺陷多动障碍儿童的体格生长和膳食特征：一项横断面研究.

    Lin, Shuang / Wu, Dan-Dan / Chen, Shu-Jin / Yan, Wu / Dou, Li-Hua / Li, Xiao-Nan

    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

    2023  Volume 25, Issue 7, Page(s) 711–717

    Abstract: Objectives: To investigate the physical growth and dietary characteristics of children with attention deficit hyperactivity disorder (ADHD), and to analyze their relationship with core symptoms of ADHD.: Methods: A total of 268 children who were ... ...

    Title translation Physical growth and dietary characteristics of children with attention deficit hyperactivity disorder: a cross-sectional study.
    Abstract Objectives: To investigate the physical growth and dietary characteristics of children with attention deficit hyperactivity disorder (ADHD), and to analyze their relationship with core symptoms of ADHD.
    Methods: A total of 268 children who were newly diagnosed with ADHD in Children's Hospital of Nanjing Medical University from June to December 2020 were included in the ADHD group, and 102 healthy children who underwent physical examination during the same period were selected as the control group. Physical evaluations and dietary surveys were conducted for both groups. ADHD diagnosis and scoring were performed according to the Diagnostic and Statistical Manual of Mental Disorders (5th edition). Factor analysis, Spearman correlation analysis, and mediation analysis were used to study the relationship between core symptoms of ADHD, dietary patterns, and physical growth.
    Results: The rate of overweight/obesity in the ADHD group was significantly higher than that in the control group (35.8% vs 21.6%,
    Conclusions: The rate of overweight/obesity in children with ADHD is higher than that in non-ADHD children. Core symptoms of ADHD are related to dietary patterns and physical growth, with the snack/fast food pattern playing a partial mediating role in the relationship between core symptoms of ADHD and physical growth.
    MeSH term(s) Humans ; Child ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Cross-Sectional Studies ; Overweight ; Pediatric Obesity ; Diet
    Language Chinese
    Publishing date 2023-08-02
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1008-8830
    ISSN 1008-8830
    DOI 10.7499/j.issn.1008-8830.2301052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Different adipose tissue depots and metabolic syndrome in human].

    Wang, Ran / Li, Xiao-Nan

    Sheng li xue bao : [Acta physiologica Sinica

    2017  Volume 69, Issue 3, Page(s) 357–365

    Abstract: Obesity is characterized by abnormal and excessive adipose tissue accumulated in the body. Compared with peripheral obesity (the accumulation of subcutaneous adipose tissue), abdominal obesity (the accumulation of visceral adipose tissue) is associated ... ...

    Abstract Obesity is characterized by abnormal and excessive adipose tissue accumulated in the body. Compared with peripheral obesity (the accumulation of subcutaneous adipose tissue), abdominal obesity (the accumulation of visceral adipose tissue) is associated with increased risk of the metabolic syndrome, such as diabetes, hypertension, atherosclerosis, and dyslipidemia. Adipose tissue is a highly heterogeneous endocrine organ. Adipose tissue depots differ significantly in anatomy, cell biology, glucose and lipid metabolism as well as in endocrine regulation. Visceral adipose tissue has a stronger metabolic activity and secrets a larger amount of free fat acids, adipocytokines, hormones and inflammatory factors, which flux into the liver directly via the hepatic portal vein. These characteristics indicate that visceral adiposity may lead to the metabolic syndrome and thus visceral adipose tissue might be the clinical target for the prevention and treatment of obesity.
    MeSH term(s) Adipose Tissue/pathology ; Humans ; Intra-Abdominal Fat/pathology ; Lipid Metabolism ; Metabolic Syndrome/physiopathology ; Obesity/physiopathology ; Obesity, Abdominal/physiopathology ; Subcutaneous Fat/pathology
    Language Chinese
    Publishing date 2017-06-25
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 604308-2
    ISSN 0371-0874
    ISSN 0371-0874
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  7. Article: [Research progress of neuregulin 4 biological function].

    Yang, Fan / Li, Xiao-Nan

    Sheng li xue bao : [Acta physiologica Sinica

    2017  Volume 69, Issue 3, Page(s) 351–356

    Abstract: Neuregulin 4 (NRG4) is a kind of protein containing epidermal growth factor (EGF)-like domains, mainly expressed and secreted by brown adipocytes. It specifically activates EGF receptor ErbB4 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog ...

    Abstract Neuregulin 4 (NRG4) is a kind of protein containing epidermal growth factor (EGF)-like domains, mainly expressed and secreted by brown adipocytes. It specifically activates EGF receptor ErbB4 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4) to stimulate cell proliferation, inhibit apoptosis and improve energy metabolism of cells. Increasing evidence has shown that NRG4 plays an important role in epithelial cell-related diseases, cardiovascular diseases, tumors and glycolipid metabolic diseases, and therefore it could be a potential therapeutic target of some diseases.
    MeSH term(s) Animals ; Apoptosis ; Cardiovascular Diseases ; Cell Proliferation ; Energy Metabolism ; Humans ; Metabolic Diseases ; Neoplasms ; Neuregulins/physiology ; Receptor, ErbB-4/physiology ; Signal Transduction
    Chemical Substances Neuregulins ; neuregulin-4 ; Receptor, ErbB-4 (EC 2.7.10.1)
    Language Chinese
    Publishing date 2017-06-25
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 604308-2
    ISSN 0371-0874
    ISSN 0371-0874
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  8. Article ; Online: Treatment of Hoffa fracture of femoral condyle with anchor combined with auxiliary fixation.

    Suo, Yan-Hui / Chen, Jun-Lin / Li, Qing-Shan / Chen, Xuan / Xie, Yan-Ping / Gu, Pei-Feng / Li, Xiao-Nan / Li, Yuan-Shen

    Journal of back and musculoskeletal rehabilitation

    2023  Volume 36, Issue 5, Page(s) 1185–1192

    Abstract: Background: A Hoffa fracture is an unstable intra-articular break that is generally treated with surgery.: Objective: To evaluate the feasibility and clinical outcomes of using a suture anchor combined with auxiliary fixation for the treatment of a ... ...

    Abstract Background: A Hoffa fracture is an unstable intra-articular break that is generally treated with surgery.
    Objective: To evaluate the feasibility and clinical outcomes of using a suture anchor combined with auxiliary fixation for the treatment of a lateral femoral condyle Hoffa fracture.
    Methods: The study retrospectively reviewed 8 patients (5 males and 3 females) with a lateral femoral condyle Hoffa fracture who had been treated by combining a suture anchor with auxiliary fixation between January 2016 and April 2020. The mean age of patients was 37.5 years (ranging from 23 to 45). According to Letenneur's classification, there were 4 cases of type I, 2 cases of type II, and 2 cases of type III fractures. The clinical outcomes were assessed using Letenneur's functional assessment.
    Results: The follow-up duration ranged between 14-24 months. All patients achieved primary healing of the incision and fracture union, as well as normal flexion and extension of the knee joint, with 7 cases showing excellent outcomes and 1 case showing a good outcome. No postoperative complications, such as fracture displacement, anchor loosening, or fracture malunion, occurred in this series.
    Conclusion: Our results indicated that a suture anchor, combined with external fixation, was an effective treatment for a lateral femoral condyle Hoffa fracture. Accordingly, this procedure is worthy of wider clinical application.
    MeSH term(s) Male ; Female ; Humans ; Adult ; Femoral Fractures/surgery ; Hoffa Fracture ; Retrospective Studies ; Fracture Fixation, Internal/methods ; Bone Screws ; Femur ; Treatment Outcome ; Knee Joint
    Language English
    Publishing date 2023-07-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1184721-9
    ISSN 1878-6324 ; 1053-8127
    ISSN (online) 1878-6324
    ISSN 1053-8127
    DOI 10.3233/BMR-220378
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  9. Article: [Progress in development and regulatory of brown adipose tissue].

    Chen, Ran / Li, Xiao-Nan

    Sheng li ke xue jin zhan [Progress in physiology

    2016  Volume 47, Issue 1, Page(s) 38–42

    MeSH term(s) Adipose Tissue, Brown/physiology ; Energy Metabolism ; Humans
    Language Chinese
    Publishing date 2016-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 259864-4
    ISSN 0559-7765
    ISSN 0559-7765
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  10. Article: [The Progress of Research About Pancreatic Lipase].

    Zhou, Shan-shan / Li, Xiao-Nan

    Sheng li ke xue jin zhan [Progress in physiology

    2015  Volume 46, Issue 1, Page(s) 6–10

    Abstract: During the digestive procedure, pancreatic lipase is known as the main enzyme in vivo for digestion and absorption of dietary fat, consisting of pancreatic triglyceride lipase, pancreatic lipase related proteins 1 and 2, bile salt - stimulated Lipase and ...

    Abstract During the digestive procedure, pancreatic lipase is known as the main enzyme in vivo for digestion and absorption of dietary fat, consisting of pancreatic triglyceride lipase, pancreatic lipase related proteins 1 and 2, bile salt - stimulated Lipase and phospholipase A2. The changes of the development pattern of pancreatic lipase have confirmed associations with metabolic diseases such as obesity, not only because age is connected with the development of pancreatic lipase, but also pancreatic lipase itself is regulated by the dietary structure and endocrine hormone.
    MeSH term(s) Animals ; Dietary Fats/metabolism ; Digestion ; Humans ; Lipase/metabolism ; Obesity/metabolism ; Phospholipases A2/metabolism ; Sterol Esterase/metabolism
    Chemical Substances Dietary Fats ; bile salt-stimulated lipase (EC 3.1.1.-) ; Sterol Esterase (EC 3.1.1.13) ; Lipase (EC 3.1.1.3) ; pancreatic lipase-related protein 1 (EC 3.1.1.3) ; Phospholipases A2 (EC 3.1.1.4)
    Language Chinese
    Publishing date 2015-06-19
    Publishing country China
    Document type Journal Article
    ZDB-ID 259864-4
    ISSN 0559-7765
    ISSN 0559-7765
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