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  1. Article: Corrigendum: A Paradigm for Matching Waking Events Into Dream Reports.

    Wang, JiaXi / He, JingYu / Bin, Ting / Ma, HuiYing / Wan, Jing / Li, XinQuan / Feng, XiaoLing / Shen, HeYong

    Frontiers in psychology

    2021  Volume 12, Page(s) 702950

    Abstract: This corrects the article DOI: 10.3389/fpsyg.2020.01430.]. ...

    Abstract [This corrects the article DOI: 10.3389/fpsyg.2020.01430.].
    Language English
    Publishing date 2021-06-04
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2021.702950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Paradigm for Matching Waking Events Into Dream Reports.

    Wang, JiaXi / He, JingYu / Bin, Ting / Ma, HuiYing / Wan, Jing / Li, XinQuan / Feng, XiaoLing / Shen, HeYong

    Frontiers in psychology

    2020  Volume 11, Page(s) 1430

    Abstract: In this study, participants recorded their waking events (Personal significant events, PSEs/Major concerns, MCs) and dream reports for 7 days. These events and dreams were paired by the same day (216 PSEs-dreams pairs and 215 MCs-dreams pairs). Then ... ...

    Abstract In this study, participants recorded their waking events (Personal significant events, PSEs/Major concerns, MCs) and dream reports for 7 days. These events and dreams were paired by the same day (216 PSEs-dreams pairs and 215 MCs-dreams pairs). Then participants were instructed to both find similar features (characters, objects, locations, actions, emotions, and themes) of their events-dreams pairs and give a match score of their events-dreams pairs. Besides, we proposed a method for independent judges to match waking events into dreams (the external ratings). The rating standard of the external-ratings was to look for similar behaviors between events and dreams. Based on this rating standard, three independent judges were instructed to rate participants' events-dreams pairs. Firstly, we compared the two kinds of methods of self-ratings. Spearman correlations showed that the two methods were significantly correlated with each other. These results suggested that the sum of different kinds of similar features could be used to represent self-ratings reported of the degree of the correlation between a waking event and a dream. Regression correlations showed that for PSEs-dreams pairs, characters, actions, emotions, and themes were similar features that affected the degree of the correlation between an event and a dream of the same day, and for MCs-dreams pairs, characters, locations, emotions, and themes were similar features that affected the degree of the correlation between an event and a dream of the same day. These results suggested that different kinds of similar features had different influence on the self-ratings' evaluation for the degree of matching between waking event and dream. Secondly, we compared the rating results of the self-ratings and the rating results of the external-ratings. Spearman correlations showed that the results of the self-ratings were significantly correlated with the results of the external-ratings. So this study's method for the external ratings may be suitable for future studies. Besides, as the external ratings of this study can rate dream metaphors, we also made a short discussion on dream metaphors. Future studies can use the method to explore dream metaphors.
    Language English
    Publishing date 2020-07-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2020.01430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Integration of waking experience through dreams considered in light of individual differences in implicit learning ability.

    Wang, JiaXi / Li, XinQuan / He, JingYu / Ma, HuiYing / Bin, Ting / Wan, Jing / Feng, XiaoLing / Zemmelman, Steve / Shen, HeYong

    Journal of sleep research

    2020  Volume 30, Issue 3, Page(s) e13171

    Abstract: The present study explored whether individual differences in implicit learning were related to the incorporation of waking events into dreams. Participants (N = 60) took part in a sequence learning task, a measure of implicit learning ability. They were ... ...

    Abstract The present study explored whether individual differences in implicit learning were related to the incorporation of waking events into dreams. Participants (N = 60) took part in a sequence learning task, a measure of implicit learning ability. They were then asked to keep a record of their waking experiences (personally significant events [PSEs]/major concerns), as well as their nightly dreams for a week. Of these, the responses of 51 participants were suitable for further analysis in which participants themselves and three independent judges rated the correlation between waking events and dreams of the same day. Implicit learning ability was found to significantly correlate with the incorporation of PSEs into dreams. The present results may lend support to the Horton and Malinowski autobiographical memory (AM) model, which accounts for the activation of memories in dreams as a reflection of sleep-dependent memory consolidation processes that focusses in particular on the hyperassociative nature of AM during sleep.
    MeSH term(s) Adult ; Dreams/physiology ; Female ; Humans ; Individuality ; Learning/physiology ; Male ; Wakefulness/physiology
    Language English
    Publishing date 2020-09-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1122722-9
    ISSN 1365-2869 ; 0962-1105
    ISSN (online) 1365-2869
    ISSN 0962-1105
    DOI 10.1111/jsr.13171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 343: Show issues

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  4. Article ; Online: The Regulating Mechanism of Chrysophanol on Protein Level of CaM-CaMKIV to Protect PC12 Cells Against Aβ

    Ye, Ting / Gao, Hua-Wu / Xuan, Wei-Ting / Ye, Shu / Zhou, Peng / Li, Xin-Quan / Wang, Yan / Song, Hang / Liu, Yan-Yan / Cai, Biao

    Drug design, development and therapy

    2020  Volume 14, Page(s) 2715–2723

    Abstract: Objective: To investigate the neuroprotective effect of chrysophanol (CHR) on PC12 treated with Aβ: Methods: After the establishment of an AD cell model induced by Aβ: Results: When pretreated with CHR before exposure to Aβ: Conclusion: CHR ... ...

    Abstract Objective: To investigate the neuroprotective effect of chrysophanol (CHR) on PC12 treated with Aβ
    Methods: After the establishment of an AD cell model induced by Aβ
    Results: When pretreated with CHR before exposure to Aβ
    Conclusion: CHR plays a neuroprotective role in AD though decreasing the protein level of CaM-CaMKK-CaMKIV and the expression of p-tau downstream.
    MeSH term(s) Amyloid beta-Peptides/antagonists & inhibitors ; Amyloid beta-Peptides/metabolism ; Animals ; Anthraquinones/metabolism ; Anthraquinones/pharmacology ; Apoptosis/drug effects ; Calcium-Calmodulin-Dependent Protein Kinase Type 4/antagonists & inhibitors ; Calcium-Calmodulin-Dependent Protein Kinase Type 4/genetics ; Calcium-Calmodulin-Dependent Protein Kinase Type 4/metabolism ; Calmodulin/antagonists & inhibitors ; Calmodulin/genetics ; Calmodulin/metabolism ; Cell Survival/drug effects ; Neuroprotective Agents/metabolism ; Neuroprotective Agents/pharmacology ; PC12 Cells ; Peptide Fragments/antagonists & inhibitors ; Peptide Fragments/metabolism ; Rats ; Tumor Cells, Cultured
    Chemical Substances Amyloid beta-Peptides ; Anthraquinones ; Calmodulin ; Neuroprotective Agents ; Peptide Fragments ; amyloid beta-protein (25-35) ; Calcium-Calmodulin-Dependent Protein Kinase Type 4 (EC 2.7.11.17) ; chrysophanic acid (N1ST8V8RR2)
    Language English
    Publishing date 2020-07-13
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2451346-5
    ISSN 1177-8881 ; 1177-8881
    ISSN (online) 1177-8881
    ISSN 1177-8881
    DOI 10.2147/DDDT.S245128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway.

    Ye, Shu / Xie, Dao-Jun / Zhou, Peng / Gao, Hua-Wu / Zhang, Meng-Ting / Chen, Da-Bao / Qin, Yun-Peng / Lei, Xin / Li, Xin-Quan / Liu, Juan / Cheng, Ya-Xun / Yao, Yong-Chuan / Cai, Biao / Shen, Guo-Ming

    Evidence-based complementary and alternative medicine : eCAM

    2021  Volume 2021, Page(s) 5514175

    Abstract: Background: Huang-Pu-Tong-Qiao formula (HPTQ), a traditional Chinese medicine (TCM) formula used to improve cognitive impairment. However, the underlying neuroprotective mechanism of HPTQ treated for diabetic cognitive dysfunction (DCD) remains unclear. ...

    Abstract Background: Huang-Pu-Tong-Qiao formula (HPTQ), a traditional Chinese medicine (TCM) formula used to improve cognitive impairment. However, the underlying neuroprotective mechanism of HPTQ treated for diabetic cognitive dysfunction (DCD) remains unclear. The purpose of this study was to investigate the neuroprotective mechanism of HPTQ in DCD mice based on molecular docking.
    Methods: To investigate the neuroprotective effect of HPTQ in DCD, the Morris water maze (MWM), novel object recognition (NOR) test was used to detect the learning and memory changes of mice; hematoxylin-eosin (HE) staining was used to investigate the damage of hippocampal neurons; the western blot (WB) was used to examine the level of brain-derived neurotrophic factor (BDNF) of hippocampus. To investigate the neuroprotective mechanism of HPTQ in DCD, molecular docking was used to predict the possible target proteins of different active components in HPTQ and then the WB was used to verify the expression of key target proteins in the hippocampus of mice.
    Results: HPTQ improved the learning and memory ability, hippocampal neuron damage, and the level of BDNF in the hippocampus of the DCD model treated with HFD/STZ for 12 weeks. Besides, the results of molecular docking showed that the main chemical components of HPTQ could be well combined with the targets of Bcl-2-associated X (Bax) and B-cell lymphoma2 (Bcl-2) and caspase-3. The levels of Bax/Bcl-2 protein ratio and caspase-3 increased in the DCD model while the HPTQ inhibited it. In addition, HPTQ restored DCD-induced decline of p-CREB, BDNF, TrkB, and p-Akt in the hippocampus.
    Conclusions: These data indicated that HPTQ ameliorates the hippocampus apoptosis in diabetic cognitive dysfunction mice by activating CREB/BDNF/TrkB signaling pathway.
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2021/5514175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article: [Metabonomic study of blood plasma in the assessment of liver graft function].

    Zhang, Qi / Gao, Jing / Li, Ling / Chen, He-Bing / Li, Xin-Quan / Yan, Xian-Zhong

    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

    2007  Volume 29, Issue 6, Page(s) 725–729

    Abstract: Objective: To access the capability of 1H nuclear magnetic resonance (NMR) -based metabonomics in the evaluation of graft function in the perioperation period of liver transplantation.: Methods: Plasma samples of 15 male primary hepatic carcinoma ... ...

    Abstract Objective: To access the capability of 1H nuclear magnetic resonance (NMR) -based metabonomics in the evaluation of graft function in the perioperation period of liver transplantation.
    Methods: Plasma samples of 15 male primary hepatic carcinoma patients were collected for clinical biochemical analysis and 1H NMR spectroscopy 1 day before operation, 1 day and 1 week after the operation. The NMR data were analyzed using principal component analysis.
    Results: Metabonomic analysis indicated that, compared with those before operation, blood concentrations of valine, alanine, acetone, succinic acid, glutamine, choline, lactate, and glucose increased significantly 1 day after transplantation. One week later, the levels of lipids and choline increased notably, while those of glucose and amino acids decreased. Principal component analysis showed significant difference between metabolic profiles of plasma samples of variant periods of liver transplantation, due to the variation of the levels of glucose, lipids, lactate, and choline. A good agreement was observed between clinical chemistry and metabonomic data.
    Conclusions: Metabonomic analysis can clearly identify the difference between the plasma samples of primary hepatic carcinoma patients at different time during the perioperation period of liver transplantation. It therefore may be a promising new technology in predicting the outcomes of liver transplantation.
    MeSH term(s) Acetone/blood ; Acetone/chemistry ; Alanine/blood ; Alanine/chemistry ; Biomarkers/blood ; Biomarkers/chemistry ; Blood Glucose/chemistry ; Blood Glucose/metabolism ; Carcinoma/blood ; Carcinoma/chemistry ; Carcinoma/surgery ; Choline/blood ; Choline/chemistry ; Glutamine/blood ; Glutamine/chemistry ; Humans ; Lactic Acid/blood ; Lactic Acid/chemistry ; Liver/metabolism ; Liver Neoplasms/blood ; Liver Neoplasms/chemistry ; Liver Neoplasms/surgery ; Liver Transplantation/physiology ; Magnetic Resonance Spectroscopy ; Male ; Metabolome ; Succinic Acid/blood ; Succinic Acid/chemistry ; Treatment Outcome ; Valine/blood ; Valine/chemistry
    Chemical Substances Biomarkers ; Blood Glucose ; Glutamine (0RH81L854J) ; Acetone (1364PS73AF) ; Lactic Acid (33X04XA5AT) ; Succinic Acid (AB6MNQ6J6L) ; Valine (HG18B9YRS7) ; Choline (N91BDP6H0X) ; Alanine (OF5P57N2ZX)
    Language Chinese
    Publishing date 2007-12
    Publishing country China
    Document type English Abstract ; Evaluation Studies ; Journal Article
    ZDB-ID 604853-5
    ISSN 1000-503X
    ISSN 1000-503X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2554: Show issues Location:
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  7. Article: [Inhibiting effect of arsenic trioxide on telomerase activity of NB4 and Jurkat cell lines].

    Wang, Yun-Fang / Sun, Hong-Yan / Wang, Quan-Li / Li, Xin-Quan

    Zhongguo shi yan xue ye xue za zhi

    2003  Volume 11, Issue 4, Page(s) 359–362

    Abstract: To investigate the inhibiting effect of arsenic trioxide (As(2)O(3)) on the telomerase activity of leukemia cell lines NB4 and Jurkat cells, MTT assay, electrophoresis of genomic DNA, protein/DNA dual parameter flow cytometry as well as a semi- ... ...

    Abstract To investigate the inhibiting effect of arsenic trioxide (As(2)O(3)) on the telomerase activity of leukemia cell lines NB4 and Jurkat cells, MTT assay, electrophoresis of genomic DNA, protein/DNA dual parameter flow cytometry as well as a semi-quantitative telomeric repeat amplification protocol (TRAP) assay and RT-PCR were used to examine the effect of As(2)O(3) on cell proliferation, telomerase activity and expression of cell cycle regulatory proteins. The results showed that cell proliferation and telomerase activity were significantly inhibited and apoptosis was induced in these cells after exposure to As(2)O(3). Furthermore, the expression of some cell cycle and apoptosis related proteins, such as Bcl-2, Rb, P16, caspase-3, cyclin A and cyclin E, was altered in As(2)O(3) treated NB4 cells. Cell cycle was arrested at G(1) and G(2)/M phases in both cells. It is concluded that the change of cell cycle regulatory proteins plays an important role in decline of the telomerase activity during the proliferation inhibition and apoptosis of NB4 and Jurkat cells induced by As(2)O(3).
    MeSH term(s) Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Arsenicals/pharmacology ; Cell Cycle/drug effects ; Cell Division/drug effects ; DNA-Binding Proteins ; Enzyme Inhibitors/pharmacology ; Humans ; Jurkat Cells ; Oxides/pharmacology ; RNA, Messenger/analysis ; Telomerase/antagonists & inhibitors ; Telomerase/genetics
    Chemical Substances Antineoplastic Agents ; Arsenicals ; DNA-Binding Proteins ; Enzyme Inhibitors ; Oxides ; RNA, Messenger ; Telomerase (EC 2.7.7.49) ; arsenic trioxide (S7V92P67HO)
    Language Chinese
    Publishing date 2003-09-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 2404306-0
    ISSN 1009-2137
    ISSN 1009-2137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6603: Show issues Location:
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