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  1. Article: The "dyadic dance": Exploring therapist-client dynamics and client symptom change using actor-partner interdependence modeling and multilevel mixture modeling.

    Li, Xu

    Journal of counseling psychology

    2021  Volume 69, Issue 4, Page(s) 474–489

    Abstract: Correction Notice: An Erratum for this article was reported in Vol 69(4) ... ...

    Abstract [Correction Notice: An Erratum for this article was reported in Vol 69(4) of
    MeSH term(s) China ; Counseling ; Humans ; Models, Psychological ; Professional-Patient Relations
    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2066555-6
    ISSN 1939-2168 ; 0022-0167
    ISSN (online) 1939-2168
    ISSN 0022-0167
    DOI 10.1037/cou0000599
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  2. Article ; Online: Yinchenhao Tang alleviates high fat diet induced NAFLD by increasing NR1H4 and APOA1 expression

    Li Xu / Hongliang Cui

    Journal of Traditional and Complementary Medicine, Vol 13, Iss 4, Pp 325-

    2023  Volume 336

    Abstract: Background and aim: Traditional Chinese medicine Yinchenhao Tang (YCHT) demonstrated benefits when treating nonalcoholic fatty liver disease (NAFLD), but the dose effects and potential targets are still ambiguous. In this study, different concentrations ... ...

    Abstract Background and aim: Traditional Chinese medicine Yinchenhao Tang (YCHT) demonstrated benefits when treating nonalcoholic fatty liver disease (NAFLD), but the dose effects and potential targets are still ambiguous. In this study, different concentrations of YCHT were employed to treat NAFLD and the underlying therapeutic targets were investigated. Experimental procedure: Kunming mice were fed with high fat diet (HFD) for 8 weeks to induce NAFLD, then treated with 3 different concentrations of YCHT. Hepatic pathological changes and serum lipid levels were examined. Network pharmacology was applied to screen the potential targets of YCHT for NAFLD modulation. NR1H4 and APOA1 expression was evaluated by QPCR and western blotting. Immunohistochemistry (IHC) staining was conducted to visualize the localization pattern of NR1H4 and APOA1 in the liver. Results: YCHT significantly reduced liver lipid storage and improved the liver pathological status of NAFLD mice. The serum lipid levels, as well as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, were remarkably reduced by the middle and high dose YCHT. There are 35 potential targets for YCHT to regulate NAFLD. HFD suppressed both RNA and protein expression of NR1H4 and APOA1, while YCHT elevated NR1H4 and APOA1 expression. IHC staining indicated that NR1H4 was mainly located in the cell nucleus and the APOA1 signal was observed at the liver sinusoid or cytoplasm. Conclusion: YCHT can effectively ameliorate HFD induced NAFLD by modulating the promising targets of NR1H4 and APOA1.
    Keywords NAFLD ; Yinchenhao tang ; Lipid metabolism ; NR1H4 ; APOA1 ; Medicine ; R
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Protocol for lentivirus-mediated delivery of genes to study neurogenesis and cognitive function in adult rodents

    Li Xu / Changyong Tang

    STAR Protocols, Vol 4, Iss 4, Pp 102761- (2023)

    2023  

    Abstract: Summary: Adult neurogenesis leads to the generation of functional neurons from neural stem cells, whereas impairment of adult hippocampal neurogenesis contributes to the pathophysiology of cognitive symptoms in neurodegenerative and neuropsychiatric ... ...

    Abstract Summary: Adult neurogenesis leads to the generation of functional neurons from neural stem cells, whereas impairment of adult hippocampal neurogenesis contributes to the pathophysiology of cognitive symptoms in neurodegenerative and neuropsychiatric diseases. Here, we present a protocol for a direct hippocampal injection of lentivirus-delivered gene in adult rodents to study the specific molecular mechanism underlying adult neurogenesis, including lentivirus packaging and stereotaxic injection, EdU and BrdU injections, tissue immunostaining and imaging analysis, and cognitive testing.For complete details on the use and execution of this protocol, please refer to Li et al. (2023).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.
    Keywords Cognitive Neuroscience ; Behavior ; Science (General) ; Q1-390
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Health poverty alleviation in China from the perspective of historical institutionalism

    Li Xu / Xiaojian You / Yinan Cui / Jiali You

    Frontiers in Public Health, Vol

    policy changes and driving factors

    2024  Volume 11

    Abstract: Health poverty alleviation is an effective tool for improving the living quality and developmental conditions of impoverished populations. Since 1978, China has been actively implementing health poverty alleviation projects, resulting in a more robust ... ...

    Abstract Health poverty alleviation is an effective tool for improving the living quality and developmental conditions of impoverished populations. Since 1978, China has been actively implementing health poverty alleviation projects, resulting in a more robust rural healthcare service network and increased convenience for the local population to access medical treatment. However, it is crucial to acknowledge that China still faces a complex situation with the simultaneous existence of multiple disease threats and the interweaving of various health influencing factors. Ongoing risks of emerging infectious diseases persist, and some previously controlled or eliminated infectious diseases are at risk of resurgence. The incidence of chronic diseases is on the rise and exhibits a trend toward affecting younger populations. Therefore, examining the successful experiences of China's health poverty alleviation over the past 40 years becomes a critically important issue. The study focuses on China's health poverty alleviation policies, employing historical institutionalism as a theoretical perspective to analyze the historical changes and evolutionary logic of health poverty alleviation policies. A historical institutionalist analytical framework for health poverty alleviation policies is constructed. The research findings reveal that China's health poverty alleviation policy has undergone three distinct periods since 1978: the initial phase (1978–2000), the exploratory phase (2000–2012), and the stable development phase (2013–present). At the macro level, the political, economic, and social contexts of different periods have influenced the evolution of health poverty alleviation policies. On the meso level, coordination effects and adaptive expectations have had an impact on China's health poverty alleviation policy. At the micro level, various actors, including the central government, local governments at different levels, social forces, and impoverished communities, interact during the evolution of health poverty alleviation ...
    Keywords health poverty alleviation ; policy changes ; historical review ; driving force ; framework of historical institutionalism ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Scalable, Flexible, and Cost-Effective Seedling Grafting.

    Yell, Victoria / Li, Xu

    Journal of visualized experiments : JoVE

    2023  , Issue 191

    Abstract: Early-stage seedling grafting has become a popular tool in molecular genetics to study root-shoot relationships within plants. Grafting early-stage seedlings of the small model plant, Arabidopsis thaliana, is technically challenging and time consuming ... ...

    Abstract Early-stage seedling grafting has become a popular tool in molecular genetics to study root-shoot relationships within plants. Grafting early-stage seedlings of the small model plant, Arabidopsis thaliana, is technically challenging and time consuming due to the size and fragility of its seedlings. A growing collection of published methods describe this technique with varying success rates, difficulty, and associated costs. This paper describes a simple procedure to make an in-house reusable grafting device using silicone elastomer mix, and how to use this device for seedling grafting. At the time of this publication, each reusable grafting device costs only $0.47 in consumable materials to produce. Using this method, beginners can have their first successfully grafted seedlings in less than 3 weeks from start to finish. This highly accessible procedure will allow plant molecular genetics labs to establish seedling grafting as a normal part of their experimental process. Due to the full control users have in the creation and design of these grafting devices, this technique could be easily adjusted for use in larger plants, such as tomato or tobacco, if desired.
    MeSH term(s) Seedlings ; Cost-Benefit Analysis ; Arabidopsis/genetics ; Plants ; Solanum lycopersicum ; Plant Roots
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/64519
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  6. Article ; Online: A Fusion Strategy for Vehicle Positioning at Intersections Utilizing UWB and Onboard Sensors.

    Gao, Huaikun / Li, Xu / Song, Xiang

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 2

    Abstract: For vehicle positioning applications in Intelligent Transportation Systems (ITS), lane-level or even more precise localization is desired in some typical urban scenarios. With the rapid development of wireless positioning technologies, ultrawide ... ...

    Abstract For vehicle positioning applications in Intelligent Transportation Systems (ITS), lane-level or even more precise localization is desired in some typical urban scenarios. With the rapid development of wireless positioning technologies, ultrawide bandwidth (UWB) has stood out and become a prominent approach for high-precision positioning. However, in traffic scenarios, the UWB-based positioning method may deteriorate because of not-line-of-sight (NLOS) propagation, multipath effect and other external interference. To overcome these problems, in this paper, a fusion strategy utilizing UWB and onboard sensors is developed to achieve reliable and precise vehicle positioning. It is a two-step approach, which includes the preprocessing of UWB raw measurements and the global estimation of vehicle position. Firstly, an ARIMA-GARCH model to address the NLOS problem of UWB at vehicular traffic scenarios is developed, and then the NLOS of UWB can be detected and corrected efficiently. Further, an adaptive IMM algorithm is developed to realize global fusion. Compared with traditional IMM, the proposed AIMM is capable of adjusting the model probabilities to make them better matching for current driving conditions, then positioning accuracy can be improved. Finally, the method is validated through experiments. Field test results verify the effectiveness and feasibility of the proposed strategy.
    Language English
    Publishing date 2024-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24020476
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  7. Article: Comparative study on curative effect and recurrence rate of chronic scapulohumeral periarthritis treated with different acupuncture techniques.

    Xu, Cheng-Chao / Li, Xu-Hao / Li, Jin-Ling

    Zhen ci yan jiu = Acupuncture research

    2024  Volume 49, Issue 2, Page(s) 164–170

    Abstract: Objectives: To observe the effects of the local stimulation with 3 acupuncture techniques, i.e. : Methods: A total of 108 patients with CSP were randomly divided into a manual acupuncture (MA) group (36 cases, one case dropped off), a WN group (36 ... ...

    Title translation 不同针法治疗慢性肩关节周围炎的疗效及复发率的对比研究.
    Abstract Objectives: To observe the effects of the local stimulation with 3 acupuncture techniques, i.e.
    Methods: A total of 108 patients with CSP were randomly divided into a manual acupuncture (MA) group (36 cases, one case dropped off), a WN group (36 cases, 3 cases dropped off) and an EA group (36 cases, 1 case dropped off). In the three groups, Jianqian (EX-UE12), Jianyu (LI15), Jianzhen (SI9), Ashi (Extra) and Yanglingquan (GB34) on the affected side were selected.
    Results: Compared with the scores before treatment, the scores of pain, joint function, and range of motion as well as the total score of Neer test were all increased after treatment in the three groups (
    Conclusions: In the treatment of CSP, the short-term effect is equivalent among EA, WN and MA. But, the analgesic effect is the best in the EA group, the treatment for anti-inflammation is the most effective in the MA and WN groups, and the needling technique of
    MeSH term(s) Humans ; Periarthritis/therapy ; Activities of Daily Living ; Dinoprostone ; Quality of Life ; Acupuncture Points ; Acupuncture Therapy ; Shoulder Pain/therapy ; Treatment Outcome
    Chemical Substances Dinoprostone (K7Q1JQR04M)
    Language Chinese
    Publishing date 2024-02-27
    Publishing country China
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1283179-7
    ISSN 1000-0607
    ISSN 1000-0607
    DOI 10.13702/j.1000-0607.20221004
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    Zs.A 4364: Show issues Location:
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  8. Article ; Online: Effects of Antibiotics on the DAMO Process and Microbes in Cattle Manure.

    He, Ting / Yin, Qidong / Li, Xu

    Environmental science & technology

    2024  Volume 58, Issue 8, Page(s) 3883–3894

    Abstract: Denitrifying anaerobic methane oxidation (DAMO) can mitigate methane emissions; however, this process has not been studied in cattle manure, an important source of methane emissions in animal agriculture. The objective of this study was to investigate ... ...

    Abstract Denitrifying anaerobic methane oxidation (DAMO) can mitigate methane emissions; however, this process has not been studied in cattle manure, an important source of methane emissions in animal agriculture. The objective of this study was to investigate the occurrence of DAMO microbes in cattle manure and examine the impacts of veterinary antibiotics on the DAMO process in cattle manure. Results show that DAMO archaea and bacteria consistently occur at high concentrations in beef cattle manure. During the long-term operation of a sequencing batch reactor seeded with beef cattle manure, the DAMO activities intensified, and DAMO microbial biomass increased. Exposure to chlortetracycline at initial concentrations up to 5000 μg L
    MeSH term(s) Cattle ; Animals ; Manure ; Methane ; Anti-Bacterial Agents/pharmacology ; RNA, Ribosomal, 16S/genetics ; Anaerobiosis ; Denitrification ; Bioreactors/microbiology ; Oxidation-Reduction ; Nitrites
    Chemical Substances Manure ; Methane (OP0UW79H66) ; Anti-Bacterial Agents ; RNA, Ribosomal, 16S ; Nitrites
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.3c07135
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  9. Article ; Online: Brain MRI and Histopathological Findings following a Heatstroke.

    Yang, Ting / Li, Xu / Li, Jun

    Neurology India

    2024  Volume 71, Issue 6, Page(s) 1288–1289

    MeSH term(s) Humans ; Heat Stroke/diagnostic imaging ; Brain/diagnostic imaging ; Brain/pathology ; Magnetic Resonance Imaging ; Brain Ischemia/pathology
    Language English
    Publishing date 2024-01-04
    Publishing country India
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.391355
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    Zs.A 698: Show issues Location:
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  10. Article ; Online: Pediatric Samples with Colorful Clues.

    Li, Xu / Interiano, Cristina / Leung-Pineda, Van

    Clinical chemistry

    2024  Volume 70, Issue 4, Page(s) 683–684

    MeSH term(s) Humans ; Child ; Excipients
    Chemical Substances Excipients
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1093/clinchem/hvae011
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