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Article ; Online: Fixing the Huai River: Technology of Labor Formation in Maoist China, 1950-53.

Li, Yujie

2024 Volume 65, Issue 1, Page(s) 177–209

Abstract: This article contributes to the large-scale engineering scholarship by revealing the labor practices involved and the state's role in shaping them. It provides a history of labor formation through earthwork technology in China's 1950s Huai River Control ... ...

Abstract	This article contributes to the large-scale engineering scholarship by revealing the labor practices involved and the state's role in shaping them. It provides a history of labor formation through earthwork technology in China's 1950s Huai River Control Project. The Communist Party's approach to engineering and labor differed from its Nationalist predecessor's. The party mobilized millions of peasants to dig and move an astronomical amount of soil in a few years. This herculean feat was made possible by promoting "work methods" to encourage peasants' self-Taylorization. The campaign aimed to cultivate a habit to work efficiently in mass-scale collaboration under external instructions. Through promoting work methods, state-appointed cadres assumed a tutelage role that allowed them to replace labor foremen. A hierarchical cadre-laborer relationship emerged from the same labor process that changed the nation's landscape.
MeSH term(s)	China ; History, 20th Century ; Rivers ; Humans ; Technology/history ; Communism/history ; Engineering/history
Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Journal Article ; Historical Article
ZDB-ID	2021131-4
ISSN	1097-3729 ; 0040-165X
ISSN (online)	1097-3729
ISSN	0040-165X
DOI	10.1353/tech.2024.a920520
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Article: The effect of psychological distance on intertemporal choice of the reward processing: an eye-tracking investigation.

Li, Yujie / Chu, Xiaoyi

Frontiers in psychology

2024 Volume 15, Page(s) 1275484

Abstract: This study employed eye-tracking technology to investigate how varying dimensions of psychological distance-temporal, probability, and social-affect intertemporal choice. Across three experiments, participants were asked to select between two ... ...

Abstract	This study employed eye-tracking technology to investigate how varying dimensions of psychological distance-temporal, probability, and social-affect intertemporal choice. Across three experiments, participants were asked to select between two intertemporal options while their eye movements were monitored. Findings revealed inconsistent impacts of different psychological distances on intertemporal decision-making. Increased temporal and social distances led to a preference for larger delayed rewards (Studies 1 and 3), whereas an increase in probability distance did not significantly alter choice preferences (Study 2). The research also highlighted a general pattern in information processing; as psychological distance widened, participants showed a tendency toward dimension-specific processing in making intertemporal decisions.
Language	English
Publishing date	2024-01-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2024.1275484
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Article ; Online: Comparison of prophylactic ipsilateral and bilateral central lymph node dissection in papillary thyroid carcinoma: a meta-analysis.

Li, Yujie / Lao, Lingling

Brazilian journal of otorhinolaryngology

2023 Volume 89, Issue 6, Page(s) 101318

Abstract: Objective: The scope of surgical resection for paratracheal (level VI) lymph nodes in patients with Papillary Thyroid Carcinoma (PTC) remains debatable. The aim of our study was to evaluate the effectiveness and safety of prophylactic ipsilateral ... ...

Abstract	Objective: The scope of surgical resection for paratracheal (level VI) lymph nodes in patients with Papillary Thyroid Carcinoma (PTC) remains debatable. The aim of our study was to evaluate the effectiveness and safety of prophylactic ipsilateral Central Neck lymph node Dissection (CND) versus bilateral CND at the time of total thyroidectomy for Clinically Node-negative (cN0) unilateral PTC. Methods: A systematic retrieval of electronic databases, including Pubmed, Web of Science, and the China Journal Net, was conducted from January 1990 to September 2021. Outcome data of interest included transient hypoparathyroidism, permanent hypoparathyroidism, transient Recurrent Laryngeal Nerve (RLN) injury, permanent RLN injury and local recurrence. We constructed the summary Odds Ratios (ORs) and 95% Confidence Intervals (CIs) for every study with either fixed or random effect models. Results: A full total of 1792 patients from 6 studies were enrolled. Our meta-analysis showed that transient hypoparathyroidism was significantly more frequent in bilateral CND group (OR=0.58; 95% CI 0.44-0.76). The prevalence of permanent hypoparathyroidism was significantly higher in bilateral CND group patients compared to those in ipsilateral CND group (OR=0.26; 95% CI 0.15-0.45). On the other hand, our meta-analysis indicated that there were no significant differences in the incidence of transient RLN injury, permanent RLN injury and local recurrence. Conclusions: Compared with bilateral CND, the rate of temporary and permanent hypoparathyroidism in ipsilateral CND is lower, but the local recurrence is similar. It may be presumptuous to suggest that ipsilateral CND is an adequate treatment for cN0 unilateral PTC.
Language	English
Publishing date	2023-09-04
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	2428110-4
ISSN	1808-8686 ; 1808-8694
ISSN (online)	1808-8686
ISSN	1808-8694
DOI	10.1016/j.bjorl.2023.101318
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Article ; Online: Application of adoptive cell therapy in hepatocellular carcinoma.

Wu, Dengqiang / Li, Yujie

Immunology

2023 Volume 170, Issue 4, Page(s) 453–469

Abstract: Hepatocellular carcinoma (HCC) remains a global health challenge. Novel treatment modalities are urgently needed to extend the overall survival of patients. The liver plays an immunomodulatory function due to its unique physiological structural ... ...

Abstract	Hepatocellular carcinoma (HCC) remains a global health challenge. Novel treatment modalities are urgently needed to extend the overall survival of patients. The liver plays an immunomodulatory function due to its unique physiological structural characteristics. Therefore, following surgical resection and radiotherapy, immunotherapy regimens have shown great potential in the treatment of hepatocellular carcinoma. Adoptive cell immunotherapy is rapidly developing in the treatment of hepatocellular carcinoma. In this review, we summarize the latest research on adoptive immunotherapy for hepatocellular carcinoma. The focus is on chimeric antigen receptor (CAR)-T cells and T cell receptor (TCR) engineered T cells. Then tumour-infiltrating lymphocytes (TILs), natural killer (NK) cells, cytokine-induced killer (CIK) cells, and macrophages are briefly discussed. The main overview of the application and challenges of adoptive immunotherapy in hepatocellular carcinoma. It aims to provide the reader with a comprehensive understanding of the current status of HCC adoptive immunotherapy and offers some strategies. We hope to provide new ideas for the clinical treatment of hepatocellular carcinoma.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/therapy ; Carcinoma, Hepatocellular/pathology ; Immunotherapy, Adoptive ; Liver Neoplasms/therapy ; Liver Neoplasms/pathology ; T-Lymphocytes ; Receptors, Antigen, T-Cell/genetics
Chemical Substances	Receptors, Antigen, T-Cell
Language	English
Publishing date	2023-07-12
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	80124-0
ISSN	1365-2567 ; 0019-2805 ; 0953-4954
ISSN (online)	1365-2567
ISSN	0019-2805 ; 0953-4954
DOI	10.1111/imm.13677
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Article ; Online: Two-Way FDI assists agricultural sustainable development: Based on digitalization and greening perspectives.

Chen, Tingwei / Yang, Feng / Li, Yujie / Zhang, Zongbin

PloS one

2024 Volume 19, Issue 2, Page(s) e0296896

Abstract: With the new challenges and crises facing agriculture, digitalization and green transformation have become important ways to solve the problems. This paper uses an international economics perspective to chart a new path for sustainable agricultural ... ...

Abstract	With the new challenges and crises facing agriculture, digitalization and green transformation have become important ways to solve the problems. This paper uses an international economics perspective to chart a new path for sustainable agricultural development. Specifically, it analyzes whether two-way international direct investment (FDI) can facilitate agricultural digital-green fusion(DGF)? Using a sample of 31 provinces (autonomous regions) from 2012 to 2021, this study finds: (1) Two-way FDI can significantly contribute to agriculture's DGF. (2) In the mechanism test, it is proved that two-way FDI can promote agriculture's DGF level by promoting green technology innovation capacity and overall regional technology innovation capacity. (3) The positive effects of two-way FDI are prominent in the eastern and central regions, coastal regions, and economically developed areas. (4) In the spatial Durbin model, the local two-way FDI growth improves agriculture's DGF level in the surrounding areas to a certain extent. The government is advised to prioritize openness, foster an environment for technological innovation, leverage spatial radiation for agricultural DGF, and advance digitally empowered agricultural modernization.
MeSH term(s)	Agriculture ; Government ; Head ; Internationality ; Investments ; Economic Development ; China
Language	English
Publishing date	2024-02-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0296896
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Article ; Online: A numerical model of the MICP multi-process considering the scale size.

Zhu, Xianxian / Wang, Jianhua / Wang, Haili / Li, Yujie

PloS one

2024 Volume 19, Issue 1, Page(s) e0297195

Abstract: As an environmentally friendly and controllable technology, Microbially induced carbonate precipitation (MICP) has broad applications in geotechnical and environmental fields. However, the longitudinal dispersivity in MICP multi-process varies with the ... ...

Abstract	As an environmentally friendly and controllable technology, Microbially induced carbonate precipitation (MICP) has broad applications in geotechnical and environmental fields. However, the longitudinal dispersivity in MICP multi-process varies with the scale size. Ignoring the effect of the scale size of the research object on the dispersivity leads to the inaccuracy between the numerical model and the experiment data. Thus, this paper has established the relationship between the scale size and the dispersivity initially, and optimized the theoretical system of MICP multi-process reaction. When scale size increases logarithmically from 10-2 m to 105 m, longitudinal dispersivity shows a trend of increasing from 10-3 m to 104 m. The distribution of calcium carbonate is closer to the experimentally measured value when the size effect is considered. After considering the scale size, the suspended bacteria and attached bacteria are higher than the cased without considering the size effect, which leads to a higher calcium carbonate content. Scale has little effect on the penetration law of the suspended bacteria. The maximum carbonate content increases with the increase of the initial porosity, and the average carbonate shows a significant increasing trend with the increase of the bacterial injecting rate. In the simulation of the microbial mineralization kinetic model, it is recommended to consider the influence of the scale size on the MICP multi-process.
MeSH term(s)	Carbonates ; Calcium Carbonate ; Bacteria ; Porosity ; Chemical Precipitation
Chemical Substances	Carbonates ; Calcium Carbonate (H0G9379FGK)
Language	English
Publishing date	2024-01-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0297195
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Article: [Research progress on immunological properties of ESAT-6 secreted by Mycobacterium tuberculosis and its role in new vaccines].

Li, Yujie / Yu, Haiyan / Yang, Yuting / Yang, Guoping

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

2024 Volume 40, Issue 1, Page(s) 89–94

Abstract: Early secreted antigenic target of 6 kDa protein (ESAT-6) is the major virulence factor of Mycobacterium tuberculosis (MTB), which can resist the clearance of MTB in bodies by inhibiting macrophage phagocytosis and autophagy reaction, thus impeding the ... ...

Abstract	Early secreted antigenic target of 6 kDa protein (ESAT-6) is the major virulence factor of Mycobacterium tuberculosis (MTB), which can resist the clearance of MTB in bodies by inhibiting macrophage phagocytosis and autophagy reaction, thus impeding the immune defense function of the body against MTB infection. In addition, ESAT-6-induced apoptosis of macrophage and massive necrosis of innate immune cells can foster MTB proliferation and colonization, leading to systemic MTB infection. Moreover, ESAT-6 hampers the protective immune response of Th1 cells, reducing the secretion of pro-inflammatory cytokines and contributing to immune dysfunction, thus accelerating the course of MTB infection. During the process, the high immunogenicity of ESAT-6 can be leveraged as a dominant antigen in the development of new TB vaccines, making it a promising candidate with broad prospects for further development.
MeSH term(s)	Humans ; Mycobacterium tuberculosis ; Vaccines ; Cytokines ; Apoptosis ; Autophagy ; Sepsis
Chemical Substances	Vaccines ; Cytokines
Language	Chinese
Publishing date	2024-01-21
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	1007-8738
ISSN	1007-8738
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Article ; Online: Preparation and characterization of Antarctic krill oil/quercetin co-loaded liposomes and their protective effect on oleic acid-induced steatosis and oxidative stress

Li, Yu-Jie / Chi, Hai / Liu, Guo-Qin

Food & function

2024 Volume 15, Issue 4, Page(s) 2103–2114

Abstract: This study aims to introduce a new liposome to co-load Antarctic krill oil (AKO) and quercetin (QC) as a new delivery formulation to enrich the application of AKO and QC. The stability of liposomes could be increased by adding an appropriate quantity of ... ...

Abstract	This study aims to introduce a new liposome to co-load Antarctic krill oil (AKO) and quercetin (QC) as a new delivery formulation to enrich the application of AKO and QC. The stability of liposomes could be increased by adding an appropriate quantity of soy lecithin (SL). Changes in the composition of the phospholipid membrane were strongly correlated with the stability and release capacity of loaded nutrients. SL2@QC/AKO-lips displayed a nearly spherical shape with higher oxidative stability and controlled the
MeSH term(s)	Animals ; Liposomes/pharmacology ; Quercetin/pharmacology ; Oleic Acid/pharmacology ; Euphausiacea ; Oils/pharmacology ; Oxidative Stress ; Lecithins
Chemical Substances	Liposomes ; Quercetin (9IKM0I5T1E) ; Oleic Acid (2UMI9U37CP) ; Oils ; Lecithins
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d3fo04291j
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Article ; Online: The impact of population aging on FDI: A panel data analysis based on 27 segments in China's manufacturing industry.

Li, Yujie / Chen, Tingwei / Zhang, Zongbin

PloS one

2024 Volume 19, Issue 2, Page(s) e0297485

Abstract: Foreign Direct Investment (FDI) is an important part of China's new "double-cycle" development pattern. Among the many factors affecting FDI, will the aging population have an impact on manufacturing, the key industry for FDI? This paper examines the ... ...

Abstract	Foreign Direct Investment (FDI) is an important part of China's new "double-cycle" development pattern. Among the many factors affecting FDI, will the aging population have an impact on manufacturing, the key industry for FDI? This paper examines the direct and indirect effects of an aging population on FDI using panel data from 27 manufacturing sub-industries in China between 2005 and 2020. It is found that (1) the deepening of the population's aging negatively affects FDI inflows and this result continues to hold after a series of robustness tests. (2) Using labor quantity and labor cost as mediating variables, it is found that the population's aging indirectly affects FDI by reducing labor quantity and increasing labor cost. (3) The heterogeneity analysis study finds that the deepening of the population's aging significantly inhibits FDI in labor-intensive and capital-intensive industries among manufacturing sub-industries, and the inhibitory effect on FDI in technology-intensive industries is not significant. This study provides meso-evidence to support the findings of existing studies and provides suggestions and insights for the government to formulate relevant policies to actively cope with aging.
MeSH term(s)	Industry ; Commerce ; Manufacturing Industry ; Technology ; Investments ; Internationality ; China ; Economic Development
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0297485
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Article ; Online: Quercetin acts as a novel anti-cancer drug to suppress cancer aggressiveness and cisplatin-resistance in nasopharyngeal carcinoma (NPC) through regulating the yes-associated protein/Hippo signaling pathway.

Li, Tao / Li, Yujie

Immunobiology

2022 Volume 228, Issue 2, Page(s) 152324

Abstract: Background: Quercetin has been proven to be effective for cancer treatment, including nasopharyngeal carcinoma (NPC). Also, Quercetin sensitizes cancer cells to current chemical drugs to improve their therapeutic efficacy. However, up until now, the ... ...

Abstract	Background: Quercetin has been proven to be effective for cancer treatment, including nasopharyngeal carcinoma (NPC). Also, Quercetin sensitizes cancer cells to current chemical drugs to improve their therapeutic efficacy. However, up until now, the molecular mechanisms that quercetin exerted its therapeutic effects on NPC have not been fully delineated. Methods: Cell proliferation abilities were examined by CCK-8 assay and colony formation assay. Real-Time qPCR and Western Blot analysis were used to detect gene expressions at RNA and protein levels. Cell mobility was determined by wound scratch assay and transwell assay. Cell death was detected using flow cytometry (FCM). Tumorigenesis of the NPC cells was determined by in vivo tumor-bearing mice models. Hematoxylin and eosin (H&E) and TUNEL staining were used to detect the tumor metastasis to lung tissues and dead cells, respectively. Results: Here, we validated that quercetin exerted its anti-tumor effects and increased cisplatin-sensitivity in NPC in vitro and in vivo. Specifically, quercetin inhibited NPC cell proliferation, viability, mobility, epithelial-mesenchymal transition (EMT), and tumorigenesis, and induced cell death, resulting in the inhibition of NPC progression. In addition, the NPC cells were subjected to a continuously increasing doses of cisplatin to generate cisplatin-resistant NPC (NPC/CDDP) cells. Interestingly, quercetin significantly enhanced the cytotoxic effects of high-dose cisplatin on NPC/CDDP cells. Furthermore, the potential underlying mechanisms were uncovered, and the results evidenced that quercetin inhibited Yes-associated protein (YAP) expression and its translocation to the nucleus, leading to the recovery of the Hippo pathway, inhibition of cancer progression, and increase in cisplatin-resistance. Mechanistically, upregulation of YAP by its gene manipulating vectors abrogated the inhibiting effects of quercetin on NPC malignant phenotypes, which also made NCP/CDDP cells irresponsive to high-dose cisplatin-quercetin co-treatments. Conclusion: Collectively, our data evidenced that quercetin inhibited YAP to recover the Hippo pathway, which further inhibited NPC pathogenesis and increased susceptibility of NCP/CDDP cells to cisplatin treatment.
MeSH term(s)	Animals ; Mice ; Cisplatin/metabolism ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Nasopharyngeal Carcinoma/drug therapy ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Carcinoma/pathology ; Hippo Signaling Pathway ; YAP-Signaling Proteins ; Quercetin/pharmacology ; Nasopharyngeal Neoplasms/drug therapy ; Nasopharyngeal Neoplasms/genetics ; Nasopharyngeal Neoplasms/pathology ; Cell Line, Tumor ; Antineoplastic Agents/therapeutic use ; Carcinogenesis/genetics ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Cell Movement
Chemical Substances	Cisplatin (Q20Q21Q62J) ; YAP-Signaling Proteins ; Quercetin (9IKM0I5T1E) ; Antineoplastic Agents
Language	English
Publishing date	2022-12-30
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	563292-4
ISSN	1878-3279 ; 0171-2985
ISSN (online)	1878-3279
ISSN	0171-2985
DOI	10.1016/j.imbio.2022.152324
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