LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 885

Search options

  1. Article ; Online: Letter on "Achalasia is Strongly Associated With Eosinophilic Esophagitis and Other Allergic Disorders".

    Li, Yun-Feng / Gau, Shuo-Yan

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2023  Volume 22, Issue 5, Page(s) 1144–1145

    MeSH term(s) Humans ; Esophageal Achalasia/complications ; Esophageal Achalasia/diagnosis ; Eosinophilic Esophagitis/complications ; Eosinophilic Esophagitis/diagnosis ; Hypersensitivity/complications
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2023.08.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: A hypothesis of monoamine (5-HT) - Glutamate/GABA long neural circuit: Aiming for fast-onset antidepressant discovery.

    Li, Yun-Feng

    Pharmacology & therapeutics

    2020  Volume 208, Page(s) 107494

    Abstract: Major depressive disorder has become a global public health problem of serious concern. Most of the clinical antidepressants are developed under the classic "monoamine hypothesis (strategy)". These drugs generally have such deficiencies including slow ... ...

    Abstract Major depressive disorder has become a global public health problem of serious concern. Most of the clinical antidepressants are developed under the classic "monoamine hypothesis (strategy)". These drugs generally have such deficiencies including slow onset and limited efficiency, cognitive impairment and suicidal tendency. Therefore, it is the direction to break through the classic monoamine strategy framework for developing antidepressants that have fast-acting, lower side effects, and cognitive enhancement, to satisfy the major clinical needs. In 2019, the launch of fast-acting antidepressants such as S-ketamine(S-Ket) and brexanolone into market by FDA has opened up new prospects for non-monoamine strategy mainly based on the N-methyl-d-aspartate (NMDA) and γ-aminobutyric acid type A (GABA
    MeSH term(s) Animals ; Antidepressive Agents/therapeutic use ; Depressive Disorder, Major/drug therapy ; Depressive Disorder, Major/physiopathology ; Drug Discovery ; Glutamic Acid/physiology ; Humans ; Neurons/physiology ; Serotonin/physiology ; gamma-Aminobutyric Acid/physiology
    Chemical Substances Antidepressive Agents ; Serotonin (333DO1RDJY) ; Glutamic Acid (3KX376GY7L) ; gamma-Aminobutyric Acid (56-12-2)
    Language English
    Publishing date 2020-01-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 194735-7
    ISSN 1879-016X ; 0163-7258
    ISSN (online) 1879-016X
    ISSN 0163-7258
    DOI 10.1016/j.pharmthera.2020.107494
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: BSSRO Improves Mandibular Morphology Mainly through Correction of Body Length and Volume in Patients with Asymmetric Mandibular Prognathism.

    Liu, Yanfei / Li, Yunfeng

    Journal of clinical medicine

    2022  Volume 11, Issue 23

    Abstract: Purpose: The purpose of this study is to analyze the change and stability of mandibular morphology in patients with asymmetric mandibular prognathism after bilateral sagittal split ramus osteotomy (BSSRO). Methods: We retrospectively analyzed fifty ... ...

    Abstract Purpose: The purpose of this study is to analyze the change and stability of mandibular morphology in patients with asymmetric mandibular prognathism after bilateral sagittal split ramus osteotomy (BSSRO). Methods: We retrospectively analyzed fifty patients with asymmetric mandibular prognathism from the West China Hospital of Stomatology, Sichuan University, between January 2018 to March 2021. The spiral CT data before surgery, within two weeks after surgery, and at more than six months after surgery of each patient were collected. According to the deflection direction of the chin, the bilateral mandibles were defined as the long side and the short side. The morphological data of the bilateral condyle, the mandibular ramus, and the mandibular body were analyzed to determine the effect and stability of BSSRO on asymmetric mandibular prognathism. Results: It was found that the long-side mandible had greater condylar volume and diameter, mandibular ramus height and volume, and mandibular body length and volume (p < 0.05) before surgery. After surgery, the volume of the mandibular ramus increased, while the length and volume of the mandibular body decreased (p < 0.05) at the long side of the mandible; the morphological changes of the mandibular ramus and body at the short side of the mandible were not statistically significant (p > 0.05). When comparing the long and short sides of the mandible, the long side still had greater height and volume of the mandibular ramus (p < 0.01). The volume difference of the mandibular body from the two sides was corrected (p > 0.05), and the length difference of the mandibular body from the two sides was overcorrected (p < 0.05). At more than six months after surgery, the volume of the mandibular ramus and body increased, while their height decreased at the long side of the mandible (p < 0.05). For the other side, or the short side, the volume of the ramus and body increased, too. However, their height decreased (p < 0.01). Conclusion: The results of this study suggested good effect and stability of BSSRO on asymmetric mandibular prognathism, except for the correction of ramus height and volume.
    Language English
    Publishing date 2022-11-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11237131
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Static hand gesture recognition based on hierarchical decision and classification of finger features.

    Li, Yunfeng / Zhang, Pengyue

    Science progress

    2022  Volume 105, Issue 1, Page(s) 368504221086362

    Abstract: ... ...

    Abstract Abstract
    MeSH term(s) Algorithms ; Fingers ; Gestures ; Pattern Recognition, Automated/methods ; Recognition, Psychology
    Language English
    Publishing date 2022-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504221086362
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Calculation method for the static carrying curve of double-row different-diameter ball slewing bearings.

    Li, Yunfeng / Wang, Rundong / Mao, Feiran

    Science progress

    2023  Volume 106, Issue 2, Page(s) 368504231180026

    Abstract: A method for calculating the static carrying curve of a double-row different-diameter ball slewing bearing was proposed. The relationship between the internal maximum rolling element load of each row and the combined external axial load and tilting ... ...

    Abstract A method for calculating the static carrying curve of a double-row different-diameter ball slewing bearing was proposed. The relationship between the internal maximum rolling element load of each row and the combined external axial load and tilting moment load of the slewing bearing was established using the deformation compatibility and force equilibrium conditions. The rolling element load distribution range parameters of the main and auxiliary raceways of the double-row different-diameter ball slewing bearing were used as input invariables, and the corresponding external load combinations of the axial and tilting moment loads of the slewing bearing were obtained. These external load combinations were plotted in the coordinate system to obtain the static carrying curve of the slewing bearing. The obtained static carrying curve was compared with that calculated using the finite element method for verification. Finally, the influences of detailed design parameters such as the raceway groove radius coefficient, raceway contact angle, and rolling element diameter on the carrying capacity of the double-row different-diameter ball slewing bearing were analyzed based on the carrying curves. As the groove radius coefficient increases from 0.515 to 0.530, or the contact angle increases from 50° to 65°, the carrying capacity of the slewing bearing decreases. As the rolling element diameter increases from 0.90 times the initial diameter to 1.05 times the initial diameter, the carrying capacity of the slewing bearing increases.
    Language English
    Publishing date 2023-06-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504231180026
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Comprehensive correction of maxillofacial bone deformity-consideration and combined application of orthognathic surgery and facial contouring surgery.

    Zhu, Song-Song / Li, Yun-Feng

    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

    2021  Volume 39, Issue 3, Page(s) 255–259

    Abstract: The maxillofacial skeleton is the basis of the contour of the face. Orthognathic surgery and facial contouring surgery change jaw tissue and affect facial appearance in different manners. Orthognathic surgery is the main method to correct dental and ... ...

    Abstract The maxillofacial skeleton is the basis of the contour of the face. Orthognathic surgery and facial contouring surgery change jaw tissue and affect facial appearance in different manners. Orthognathic surgery is the main method to correct dental and maxillofacial deformities. It changes the shape of the jaw and improves the occlusal relationship by changing the three-dimensional position of the jaw. Facial contouring surgery mainly adopts the method of "bone reduction", which changes the "amount"of the jawbone by cutting a part of the bone tissue to improve the facial appearance, generally without changing oral function. The combined use of orthognathic surgery and facial contouring surgery is becoming increasingly common in clinical practice. This also requires oral and maxillofacial surgeons to have a holistic consideration of the comprehensive correction of maxillofacial bone deformity, and to perform comprehensive analysis of jaw deformities and jaw plastic surgery to achieve the most ideal results. The author's team has been engaged in the clinical work of orthognathic surgery and facial contouring surgery and accumulated rich clinical experience in the comprehensive correction of maxillofacial bone deformity. In this article, the indications, treatment goals, treatment modes, treatment methods, and key points in the surgical operations of comprehensive maxillofacial bone surgery were summarized.
    MeSH term(s) Face/surgery ; Facial Bones ; Humans ; Maxillofacial Abnormalities ; Orthognathic Surgery ; Orthognathic Surgical Procedures
    Language Chinese
    Publishing date 2021-05-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 1202342-5
    ISSN 2618-0456 ; 1000-1182
    ISSN (online) 2618-0456
    ISSN 1000-1182
    DOI 10.7518/hxkq.2021.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Simulation of Daily Transpiration of Tomatoes Grown in Venlo-Type Greenhouse Substrates.

    Yi, Ping / Qiang, Xiaoman / Liu, Shengxing / Han, Yang / Li, Yunfeng / Liu, Hao / Wang, Jinglei

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: An appropriate water supply strategy is imperative for obtaining tomatoes of a high yield and quality; the lack of one has caused resource wastage and quality deterioration. To determine the suitable irrigation amount and simulate daily transpiration ... ...

    Abstract An appropriate water supply strategy is imperative for obtaining tomatoes of a high yield and quality; the lack of one has caused resource wastage and quality deterioration. To determine the suitable irrigation amount and simulate daily transpiration under these optimal irrigation conditions, a two-year greenhouse cultivation experiment was conducted over 2022-2023. Commencing at anthesis, three distinct irrigation gradients were triggered and designated as irrigation controls with the lower limits set at 80% (T1), 70% (T2), and 60% (T3) of the substrate water-holding capacity. We determined the optimal irrigation amount by ranking the treatments using the TOPSIS method, balancing the tomato yield and quality. A segmented daily transpiration model under optimal irrigation conditions driven by crop and environmental factors was established using the Marquardt method and data from 2022, and the model was validated using data from 2023. The results indicated that T2 was the optimal irrigation amount, with the water use efficiency increased by 18.0%, but with a 10.9% decrease in yield, while the quality indices improved significantly. The
    Language English
    Publishing date 2024-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13030374
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: The Role of Neuromodulation and Potential Mechanism in Regulating Heterotopic Ossification.

    Li, Dengju / Liu, Changxing / Wang, Haojue / Li, Yunfeng / Wang, Yaqi / An, Senbo / Sun, Shui

    Neurochemical research

    2024  

    Abstract: Heterotopic ossification (HO) is a pathological process characterized by the aberrant formation of bone in muscles and soft tissues. It is commonly triggered by traumatic brain injury, spinal cord injury, and burns. Despite a wide range of evidence ... ...

    Abstract Heterotopic ossification (HO) is a pathological process characterized by the aberrant formation of bone in muscles and soft tissues. It is commonly triggered by traumatic brain injury, spinal cord injury, and burns. Despite a wide range of evidence underscoring the significance of neurogenic signals in proper bone remodeling, a clear understanding of HO induced by nerve injury remains rudimentary. Recent studies suggest that injury to the nervous system can activate various signaling pathways, such as TGF-β, leading to neurogenic HO through the release of neurotrophins. These pathophysiological changes lay a robust groundwork for the prevention and treatment of HO. In this review, we collected evidence to elucidate the mechanisms underlying the pathogenesis of HO related to nerve injury, aiming to enhance our understanding of how neurological repair processes can culminate in HO.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-024-04118-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Spatial distribution dynamics for

    Li, Yunfeng / Wang, Yan / Du, Xiaojuan / Zhao, Chunying / He, Ping / Meng, Fanyun

    Ecology and evolution

    2024  Volume 14, Issue 2, Page(s) e11010

    Abstract: At different time scales, a species will experience diverse distribution changes. ... ...

    Abstract At different time scales, a species will experience diverse distribution changes. For
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.11010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Adult classic Bartter syndrome: a case report with 5-year follow-up and literature review.

    Jiang, Le / Li, Dongmei / Guo, Qiansha / Li, Yunfeng / Zan, Lei / Ao, Rihan

    Endocrine journal

    2024  

    Abstract: Bartter syndrome (BS) is a rare, inherited salt-losing renal tubular disorder characterized by secondary hyperaldosteronism, hypokalemia, hypochloremia, metabolic alkalosis, and low-to-normal blood pressure. Classic BS, or BS Type 3, the most common ... ...

    Abstract Bartter syndrome (BS) is a rare, inherited salt-losing renal tubular disorder characterized by secondary hyperaldosteronism, hypokalemia, hypochloremia, metabolic alkalosis, and low-to-normal blood pressure. Classic BS, or BS Type 3, the most common subtype in the Asian population, is caused by a molecular defect in ClC-Kb, a voltage-gated chloride channel in renal tubules, due to CLCNKB gene mutation. Because the onset of BS is more common in children than in adults, the diagnosis, treatment outcomes, genotype/phenotype association, and follow-up of adult-onset BS Type 3 are limited. This case report describes the findings in a 20-year-old man who was admitted with hypokalemic paralysis, with clinical manifestations were similar to those of Gitelman syndrome (GS); however, the patient was later diagnosed to have BS Type 3 through genetic testing (NM_000085.4 (CLCNKB): c.1052G>T). A literature review showed that no homozygous mutations have been reported to date. After 5 years of treatment and follow-up, we found that this genotype requires high levels of potassium and is prone to urinary protein and metabolic syndrome. Distinguishing adult-onset BS from GS is challenging in clinical practice. However, genetic diagnosis can help solve this problem effectively, and genotypes play a guiding role in treatment planning.
    Language English
    Publishing date 2024-03-19
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1151918-6
    ISSN 1348-4540 ; 0918-8959
    ISSN (online) 1348-4540
    ISSN 0918-8959
    DOI 10.1507/endocrj.EJ23-0631
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top