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Article ; Online: Coupling analysis of crane accident risks based on Bayesian network and the N-K model.

Wu, Bang-Jie / Jin, Liang-Hai / Zheng, Xia-Zhong / Chen, Shu

2024 Volume 14, Issue 1, Page(s) 1133

Abstract: Crane usage is pervasive on construction sites, however, it is associated with a notably high accident rate. The analyzing of crane accident risks is essential for accident prevention, control, and ensuring the safety of lifting operations. Hence, ... ...

Abstract	Crane usage is pervasive on construction sites, however, it is associated with a notably high accident rate. The analyzing of crane accident risks is essential for accident prevention, control, and ensuring the safety of lifting operations. Hence, significant emphasis should be placed on understanding the interaction among various risk factors. This paper proposes a quantitative coupling method for human, machine, management, and environmental risk factors in crane accidents, leveraging Bayesian networks (BN) and the N-K model. Firstly, text mining technology and fault tree analysis are employed to analyze the causes of crane accidents and categorize the associate risk factors. Secondly, the types of risk coupling resulting from human, machine, management, and environmental risk factors are defined. Thirdly, the BN model is developed based on the analysis of crane accident risksand its N-K model. Fourthly, the parameters of the risk coupling nodes in the developed BN are determined based on the calculation results of the N-K model. Finally, for the risk coupling types with high coupling values and the first-level node and second-level node, the failure probability is analyzed through posterior probability and sensitivity analysis. The results indicate that factors related to man and management significantly impact crane accidents and warrant enhanced attention. The interplay among multiple risk factors significantly influences the probability of crane accidents, necessitating careful attention.
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-51425-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Coupling analysis of crane accident risks based on Bayesian network and the N-K model

Bang-Jie Wu / Liang-Hai Jin / Xia-Zhong Zheng / Shu Chen

Scientific Reports, Vol 14, Iss 1, Pp 1-

2024 Volume 13

Abstract: Abstract Crane usage is pervasive on construction sites, however, it is associated with a notably high accident rate. The analyzing of crane accident risks is essential for accident prevention, control, and ensuring the safety of lifting operations. ... ...

Abstract	Abstract Crane usage is pervasive on construction sites, however, it is associated with a notably high accident rate. The analyzing of crane accident risks is essential for accident prevention, control, and ensuring the safety of lifting operations. Hence, significant emphasis should be placed on understanding the interaction among various risk factors. This paper proposes a quantitative coupling method for human, machine, management, and environmental risk factors in crane accidents, leveraging Bayesian networks (BN) and the N-K model. Firstly, text mining technology and fault tree analysis are employed to analyze the causes of crane accidents and categorize the associate risk factors. Secondly, the types of risk coupling resulting from human, machine, management, and environmental risk factors are defined. Thirdly, the BN model is developed based on the analysis of crane accident risksand its N-K model. Fourthly, the parameters of the risk coupling nodes in the developed BN are determined based on the calculation results of the N-K model. Finally, for the risk coupling types with high coupling values and the first-level node and second-level node, the failure probability is analyzed through posterior probability and sensitivity analysis. The results indicate that factors related to man and management significantly impact crane accidents and warrant enhanced attention. The interplay among multiple risk factors significantly influences the probability of crane accidents, necessitating careful attention.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Strong Metal-Support Interactions through Sulfur-Anchoring of Metal Catalysts on Carbon Supports.

Yin, Peng / Yan, Qiang-Qiang / Liang, Hai-Wei

Angewandte Chemie (International ed. in English)

2023 Volume 62, Issue 24, Page(s) e202302819

Abstract: In supported metal catalysts, the supports would strongly interact with the metal components instead of just acting as a carrier, which greatly affects both of their synthesis and catalytic activity, selectivity, and stability. Carbon is considered as ... ...

Abstract	In supported metal catalysts, the supports would strongly interact with the metal components instead of just acting as a carrier, which greatly affects both of their synthesis and catalytic activity, selectivity, and stability. Carbon is considered as very important but inert support and thus hard to induce strong metal-support interaction (SMSI). This mini-review highlights that sulfur-a documented poison reagent for metal catalysts-when doped in a carbon supports can induce diverse SMSI phenomenon, including electronic metal-support interaction (EMSI), classic SMSI, and reactive metal-support interaction (RMSI). These SMSI between metal and sulfur-doped carbon (S-C) supports enables the catalysts with extraordinary resistance to sintering at high temperatures of up to 1100 °C, which allows the general synthesis of single-atom, alloy cluster, and intermetallic compound catalysts with high dispersion and metal loading for a variety of applications.
Language	English
Publishing date	2023-04-19
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2011836-3
ISSN	1521-3773 ; 1433-7851
ISSN (online)	1521-3773
ISSN	1433-7851
DOI	10.1002/anie.202302819
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Article ; Online: Inhibition of HOXD11 promotes cartilage degradation and induces osteoarthritis development.

Hong, Quan / Liu, Zhong-Xun / Liang, Hai-Feng / Wu, De-Guang / Chen, Yan / Yu, Bo

Journal of orthopaedic surgery and research

2024 Volume 19, Issue 1, Page(s) 111

Abstract: The 5'-HOXD genes are important for chondrogenesis in vertebrates, but their roles in osteoarthritis (OA) are still ambiguous. In our study, 5'-HOXD genes involvement contributing to cartilage degradation and OA was investigated. In bioinformatics ... ...

Abstract	The 5'-HOXD genes are important for chondrogenesis in vertebrates, but their roles in osteoarthritis (OA) are still ambiguous. In our study, 5'-HOXD genes involvement contributing to cartilage degradation and OA was investigated. In bioinformatics analysis of 5'-HOXD genes, we obtained the GSE169077 data set related to OA in the GEO and analyzed DEGs using the GEO2R tool attached to the GEO. Then, we screened the mRNA levels of 5'-HOXD genes by quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR). We discovered that OA chondrocyte proliferation was inhibited, and apoptosis was increased. Moreover, it was discovered that SOX9 and COL2A1 were downregulated at mRNA and protein levels, while matrix metalloproteinases (MMPs) and a disintegrin-like and metalloproteinase with thrombospondin motifs (ADAMTSs) were upregulated. According to the results of differentially expressed genes (DEGs) and qRT-PCR, we evaluated the protein level of HOXD11 and found that the expression of HOXD11 was downregulated, reversed to MMPs and ADAMTSs but consistent with the cartilage-specific factors, SOX9 and COL2A1. In the lentivirus transfection experiments, HOXD11 overexpression reversed the effects in OA chondrocytes. In human OA articular cartilage, aberrant subchondral bone was formed in hematoxylin-eosin (H&E) and Safranin O and fast green (SOFG) staining results. Furthermore, according to immunohistochemistry findings, SOX9 and HOXD11 expression was inhibited. The results of this study established that HOXD11 was downregulated in OA cartilage and that overexpression of HOXD11 could prevent cartilage degradation in OA.
MeSH term(s)	Animals ; Humans ; Cartilage, Articular/metabolism ; Chondrocytes/metabolism ; Matrix Metalloproteinases/metabolism ; Osteoarthritis/genetics ; Osteoarthritis/metabolism ; RNA, Messenger/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
Chemical Substances	Matrix Metalloproteinases (EC 3.4.24.-) ; RNA, Messenger ; Transcription Factors ; HOXD11 protein, human
Language	English
Publishing date	2024-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2252548-8
ISSN	1749-799X ; 1749-799X
ISSN (online)	1749-799X
ISSN	1749-799X
DOI	10.1186/s13018-024-04573-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Omnidirectional Virtual Visual Acuity: A User-Centric Visual Clarity Metric for Virtual Reality Head-Mounted Displays and Environments.

Wang, Jialin / Shi, Rongkai / Li, Xiaodong / Wei, Yushi / Liang, Hai-Ning

IEEE transactions on visualization and computer graphics

2024 Volume 30, Issue 5, Page(s) 2033–2043

Abstract: Users' perceived image quality of virtual reality head-mounted displays (VR HMDs) is determined by multiple factors, including the HMD's structure, optical system, display and render resolution, and users' visual acuity (VA). Existing metrics such as ... ...

Abstract	Users' perceived image quality of virtual reality head-mounted displays (VR HMDs) is determined by multiple factors, including the HMD's structure, optical system, display and render resolution, and users' visual acuity (VA). Existing metrics such as pixels per degree (PPD) have limitations that prevent accurate comparison of different VR HMDs. One of the main limitations is that not all VR HMD manufacturers released the official PPD or details of their HMDs' optical systems. Without these details, developers and users cannot know the precise PPD or calculate it for a given HMD. The other issue is that the visual clarity varies with the VR environment. Our work has identified a gap in having a feasible metric that can measure the visual clarity of VR HMDs. To address this gap, we present an end-to-end and user-centric visual clarity metric, omnidirectional virtual visual acuity (OVVA), for VR HMDs. OVVA extends the physical visual acuity chart into a virtual format to measure the virtual visual acuity of an HMD's central focal area and its degradation in its noncentral area. OVVA provides a new perspective to measure visual clarity and can serve as an intuitive and accurate reference for VR applications sensitive to visual accuracy. Our results show that OVVA is a simple yet effective metric for comparing VR HMDs and environments.
MeSH term(s)	Computer Graphics ; Virtual Reality ; Visual Acuity ; Smart Glasses
Language	English
Publishing date	2024-04-19
Publishing country	United States
Document type	Journal Article
ISSN	1941-0506
ISSN (online)	1941-0506
DOI	10.1109/TVCG.2024.3372127
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Chemokine CXCL7 is Correlated with LDH-A and Predicts the Prognosis of Patients with Colorectal Cancer.

Liang, Hai / Li, Longhai / Huang, Baoyu / Cheng, Gang / Ao, Jiafu / Hao, Shuli

Frontiers in bioscience (Landmark edition)

2024 Volume 29, Issue 4, Page(s) 166

Abstract: Objective: The aims of this study were to evaluate the correlation between chemokine (C-X-C) ligand 7 (CXCL7) expression and glycolysis and to explore the prognostic significance of CXCL7 in colorectal cancer (CRC).: Methods: The expression of CXCL7 ... ...

Abstract	Objective: The aims of this study were to evaluate the correlation between chemokine (C-X-C) ligand 7 (CXCL7) expression and glycolysis and to explore the prognostic significance of CXCL7 in colorectal cancer (CRC). Methods: The expression of CXCL7 and lactate dehydrogenase A (LDH-A) was measured by immunohistochemistry in tissue from 158 CRC patients. Patients were divided into high expression and low expression groups based on receiver operating characteristic curves and a cut-off value. The correlation between CXCL7 and LDH-A expression was evaluated. The overall survival (OS) times of CRC patients were explored. The risk factors related to prognosis were assessed. Results: Significantly higher expression of CXCL7 and LDH-A was detected in CRC tissue than in non-CRC tissue, and was associated with N stage and tumor-node-metastasis (TNM) stage. CXCL7 expression was strongly correlated with LDH-A expression in CRC tissue. High expression of CXCL7 was validated as an independent risk factor for OS. Conclusion: Increased expression of CXCL7 was positively correlated with LDH-A expression and was an independent risk factor for CRC prognosis.
MeSH term(s)	Humans ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/genetics ; Female ; Male ; Prognosis ; Middle Aged ; Aged ; L-Lactate Dehydrogenase/metabolism ; beta-Thromboglobulin/metabolism ; Biomarkers, Tumor/metabolism ; Adult ; Immunohistochemistry ; Risk Factors
Chemical Substances	L-Lactate Dehydrogenase (EC 1.1.1.27) ; beta-Thromboglobulin ; Biomarkers, Tumor ; LDHA protein, human (EC 1.1.1.27)
Language	English
Publishing date	2024-04-29
Publishing country	Singapore
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2704569-9
ISSN	2768-6698 ; 2768-6698
ISSN (online)	2768-6698
ISSN	2768-6698
DOI	10.31083/j.fbl2904166
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Article: A complete chloroplast genome of a traditional Chinese medicine herb,

Zhao, Shu-Ying / Muchuku, John K / Liang, Hai-Ying / Wang, Qing-Feng

Physiology and molecular biology of plants : an international journal of functional plant biology

2023 Volume 29, Issue 6, Page(s) 843–853

Abstract: Rubia podantha: Supplementary information: The online version contains supplementary material available at 10.1007/s12298-023-01302-y. ...

Abstract	Rubia podantha Supplementary information: The online version contains supplementary material available at 10.1007/s12298-023-01302-y.
Language	English
Publishing date	2023-06-20
Publishing country	India
Document type	Journal Article
ZDB-ID	2487126-6
ISSN	0974-0430 ; 0971-5894
ISSN (online)	0974-0430
ISSN	0971-5894
DOI	10.1007/s12298-023-01302-y
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Article ; Online: Development and Field Application of an Automated Pipe Jacking Friction Resistance Identification and Warning System in Construction

Liang-Hai Jin / Bang-Jie Wu / Xia-Zhong Zheng / Shu Chen

Applied Sciences, Vol 13, Iss 23, p

2023 Volume 12814

Abstract: Minimizing frictional resistance is crucial for ensuring the safety and smooth progress of pipe jacking construction. However, due to the unpredictability of geological conditions, it is difficult to grasp the frictional resistance during construction, ... ...

Abstract	Minimizing frictional resistance is crucial for ensuring the safety and smooth progress of pipe jacking construction. However, due to the unpredictability of geological conditions, it is difficult to grasp the frictional resistance during construction, which poses challenges to safe and smooth construction. In order to reduce the frictional resistance during the process of pipe jacking, an automated pipe jacking friction resistance identification and warning system is thus innovatively proposed. This system uses jacking resistance sensors to identify resistance during the jacking process. When the jacking resistance exceeds a certain threshold, the system will send alerts, which could prompt construction workers to adjust the rheological slurry ratio according to the on-site soil conditions. This system includes the following major components: (1) an analysis of primary factors influencing pipe frictional resistance and a model for resistance calculation, (2) the examination of forces exerted on disturbed soil during pipe jacking construction to determine the optimal placement of resistance sensors, (3) the design and operational principles for an automated resistance identification and warning system, and (4) the application of a slurry shield construction method for resistance reduction. The research has practical significance in providing a reference for developing intelligent pipe jacking and contributing to the improvement in construction safety levels.
Keywords	slurry pipe jacking ; construction ; friction resistance ; sensors ; geology conditions ; early warning ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	690
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: MiR-873, as a suppressor in cervical cancer, inhibits cells proliferation, invasion and migration via negatively regulating ULBP2.

Liang, Hai-Xia / Li, Yu-Hong

Genes & genomics

2020 Volume 42, Issue 4, Page(s) 371–382

Abstract: Background: Cervical cancer (CC) remains a large burden in the developing countries. The tumor inhibitory role of miR-873 has been verified in a variety of cancers, however, whether miR-873 has a suppressive effect on CC remains unclear.: Objective: ... ...

Abstract	Background: Cervical cancer (CC) remains a large burden in the developing countries. The tumor inhibitory role of miR-873 has been verified in a variety of cancers, however, whether miR-873 has a suppressive effect on CC remains unclear. Objective: The purpose of this study was to investigate the functional role of miR-873 in CC, as well as explore the underlying molecular mechanism. Methods: The prognostic values of miR-873 were assessed by Kaplan-Meier methods and cox regression models using the data which were downloaded from TCGA database. The expression of miR-873 was measured by RT-qPCR. Cell counting Kit-8, clone formation, and Transwell assays were used to assess the cell viability and metastasis, appropriately. The targeting relationship between miR-873 and ULBP2 was predicted by biological software and confirmed by dual luciferase reporter assay. Rescue assays were conducted to investigate whether miR-873 affects the phenotype of CC cells via regulating ULBP2. Results: We observed that miR-873 was low-expressed in CC. Up-regulation of miR-873 notably restrained the proliferation, invasion and migration of C33a cells. Meanwhile, down-regulation of miR-873 in SiHa cells presented the opposite outcomes. ULBP2 was forecasted and certified as a target of miR-873. The results of rescue assays showed that overexpression of ULBP2 could restore the proliferation and motility of CC cells that inhibited by miR-873. Conclusion: MiR-873 suppressed the CC cells proliferation, invasion and migration via negatively regulating ULBP2, suggesting that miR-873 could serve as a valuable therapeutic target for CC therapy.
MeSH term(s)	Cell Line ; Cell Movement ; Cell Proliferation ; Female ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; Gene Expression Regulation, Neoplastic ; HeLa Cells ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/metabolism
Chemical Substances	GPI-Linked Proteins ; Intercellular Signaling Peptides and Proteins ; MIRN873 microRNA, human ; MicroRNAs ; ULBP2 protein, human
Language	English
Publishing date	2020-01-04
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2504587-8
ISSN	2092-9293 ; 1976-9571
ISSN (online)	2092-9293
ISSN	1976-9571
DOI	10.1007/s13258-019-00905-8
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Article ; Online: Breaking trade-off between particle size and ordering degree of intermetallic catalysts for fuel cells

Song, Tian-Wei / Zuo, Lu-Jie / Zuo, Ming / Liang, Hai-Wei

Journal of Catalysis. 2023 Mar., v. 419 p.19-25

2023

Abstract: Atomically ordered intermetallic catalysts exhibit superior intrinsic activity over their disordered alloy counterparts for oxygen-reduction reaction in proton-exchange-membrane fuel cells. However, in traditional wet-impregnation method, the synthesis ... ...

Abstract	Atomically ordered intermetallic catalysts exhibit superior intrinsic activity over their disordered alloy counterparts for oxygen-reduction reaction in proton-exchange-membrane fuel cells. However, in traditional wet-impregnation method, the synthesis conditions for intermetallic catalysts such as high-temperature annealing inevitably accelerate metal sintering that leads to larger particles and thus lower mass-based activity. Herein, we quantitatively analyze the particle size, alloying degree, and ordering degree of a family of PtFe and PtCo catalysts with varied metal loading, annealing temperature, and carbon supports. We identify the trade-off between particle size and alloying/ordering degree is dependent on the inter-particle distance and annealing temperature. Accordingly, we achieve the optimal balance to prepare intermetallic PtFe catalysts with a small average particle size of 2.65 nm and a high ordering degree of 73 % simultaneously. The optimal PtFe catalyst exhibits a high mass activity of 2.1 and 0.78 A mgPₜ–¹ at 0.9 VᵢR₋cₒᵣᵣₑcₜₑd in half-cell and single-cell tests, respectively.
Keywords	alloys ; carbon ; catalysts ; catalytic activity ; fuels ; particle size ; temperature ; Intermetallic catalysts ; Trade-off ; Ordering degree ; Fuel cells
Language	English
Dates of publication	2023-03
Size	p. 19-25.
Publishing place	Elsevier Inc.
Document type	Article ; Online
ZDB-ID	1468993-5
ISSN	1090-2694 ; 0021-9517
ISSN (online)	1090-2694
ISSN	0021-9517
DOI	10.1016/j.jcat.2023.01.026
Database	NAL-Catalogue (AGRICOLA)

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