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Article ; Online: A Case Study of Edge Computing Implementations

Liang Tian / Xiaorou Zhong

Journal of Computing and Information Technology, Vol 30, Iss 3, Pp 139-

Multi-access Edge Computing, Fog Computing and Cloudlet

2022 Volume 159

Abstract: With the explosive growth of intelligent and mobile devices, the current centralized cloud computing paradigm is encountering difficult challenges. Since the primary requirements have shifted towards implementing real-time response and supporting context ...

Abstract	With the explosive growth of intelligent and mobile devices, the current centralized cloud computing paradigm is encountering difficult challenges. Since the primary requirements have shifted towards implementing real-time response and supporting context awareness and mobility, there is an urgent need to bring resources and functions of centralized clouds to the edge of networks, which has led to the emergence of the edge computing paradigm. Edge computing increases the responsibilities of network edges by hosting computation and services, therefore enhancing performances and improving quality of experience (QoE). Fog computing, multi-access edge computing (MEC), and cloudlet are three typical and promising implementations of edge computing. Fog computing aims to build a system that enables cloud-to-thing service connectivity and works in concert with clouds, MEC is seen as a key technology of the fifth generation (5G) system, and Cloudlet is a micro-data center deployed in close proximity. In terms of deployment scenarios, Fog computing focuses on the Internet of Things (IoT), MEC mainly provides mobile RAN application solutions for 5G systems, and cloudlet offloads computing power at the network edge. In this paper, we present a comprehensive case study on these three edge computing implementations, including their architectures, differences, and their respective application scenario in IoT, 5G wireless systems, and smart edge. We discuss the requirements, benefits, and mechanisms of typical co-deployment cases for each paradigm and identify challenges and future directions in edge computing.
Keywords	multi-access edge computing ; cloudlet ; 5G ; fog computing ; cloud computing ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	303
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	University of Zagreb Faculty of Electrical Engineering and Computing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Intestine proteomic and metabolomic alterations in dogs infected with Toxocara canis.

Wang, Na / Sieng, Soben / Liang, Tian / Xu, Jingyun / Han, Qian

Acta tropica

2024 Volume 252, Page(s) 107140

Abstract: Toxocariasis is an important zoonotic parasitic disease. Toxocaris canis adults live and reproduce in the intestinal tract of dogs and other canine hosts, and the infectious eggs are continuously excreted in feces, which causes environmental ... ...

Abstract	Toxocariasis is an important zoonotic parasitic disease. Toxocaris canis adults live and reproduce in the intestinal tract of dogs and other canine hosts, and the infectious eggs are continuously excreted in feces, which causes environmental contamination and has an important public health significance. In this study, TMT proteomic and untargeted metabolomic methods were used to explore the physiological and pathological effects on the intestinal tract of dogs which infected with T. canis, and a series of bioinformatics analyses were conducted to identify differentially expressed proteins (DEPs) and differentially expressed metabolites (DEMs). The proteomics results showed that 198 DEPs were mainly enriched in the immune system and signal transduction pathway, and involved in the regulation of the occurrence and development of cancer and infectious diseases. T. canis could disrupt intestinal permeability by increasing the expression of proteins such as zinc finger protein DZIP1L and myosin heavy chain 10. Additionally, T. canis infection could also inhibit the host immune response by decreasing the expression of MHC-II, NF-κB, DLA and other immune-related molecules. While, the metabolomics results revealed that the expression of oxoglutaric acid, glutamate, d-aspartate, arginine, taurochenodeoxycholic acid and taurocholic acid which participated in tricarboxylic acid (TCA) cycle, glycolysis/gluconeogenesis, bile secretion, biosynthesis of amino acids pathway were significantly decreased. The correlation results of proteomics and metabolomics showed that DEPs and DEMs were mainly co-enriched in bile secretion pathway to regulate intestinal peristalsis. Analyzing DEPs and DEMs will not only provide insights into the mechanisms of host parasite interaction, but also aid in identifying potential targets for therapy and diagnosis, thus setting the groundwork for effectively preventing and managing toxocariasis.
MeSH term(s)	Animals ; Dogs ; Toxocara canis ; Toxocariasis ; Proteomics ; Dog Diseases/epidemiology ; Zoonoses ; Intestines
Language	English
Publishing date	2024-02-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	210415-5
ISSN	1873-6254 ; 0001-706X
ISSN (online)	1873-6254
ISSN	0001-706X
DOI	10.1016/j.actatropica.2024.107140
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Article ; Online: Can Sugarcane Yield and Health Be Altered with Fully Mechanized Management?

Xiao, Jian / Liang, Tian / Yang, Shangdong / Tan, Hongwei

Agronomy. 2023 Jan. 03, v. 13, no. 1

2023

Abstract: At present, fully mechanized cultivation (FMC) has begun to be utilized in commercial sugarcane production in China. To provide new insights into whether cane yield and health are altered by fully mechanized cultivations, the cane yield and endophytic ... ...

Abstract	At present, fully mechanized cultivation (FMC) has begun to be utilized in commercial sugarcane production in China. To provide new insights into whether cane yield and health are altered by fully mechanized cultivations, the cane yield and endophytic microbial community structure in stems of sugarcane that underwent fully mechanized cultivation (FMC) and conventional artificial cultivation (CAC) were compared. The results showed that the diversity and richness of endophytic microorganisms, except for the bacterial richness in the stems of sugarcane, could be significantly increased by using FMC. Meanwhile, in comparison with CAC, the relative abundance of Proteobacteria and Ascomycota increased under FMC. Moreover, some dominant endophytic bacterial genera, such as Acidovorax, Microbacterium, and Paenibacillus, and some dominant endophytic fungal genera, such as Scleroramularia, Tetraplosphaeria, and Dinemasporium, were found to be significantly enriched in cane stems under FMC treatments. Additionally, the endophytic microbial functions in sugarcane stems were not significantly altered by FMC treatments. Our results suggest that cane growth, yield, and health are not significantly altered by FMC. The results also indicate that fully mechanized management can be developed as a sustainable method in sugarcane production.
Keywords	Acidovorax ; Ascomycota ; Microbacterium ; Paenibacillus ; agronomy ; community structure ; endophytes ; fungi ; mechanization ; microbial communities ; sugarcane ; China
Language	English
Dates of publication	2023-0103
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2607043-1
ISSN	2073-4395
ISSN	2073-4395
DOI	10.3390/agronomy13010153
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Do full mechanized management strategies destroy soil health and fertility in sugarcane fields?

Xiao, Jian / Liang, Tian / Yang, Shangdong / Tan, Hongwei

Catena. 2023 May, v. 224 p.107000-

2023

Abstract: To provide new insights into whether soil health and fertility in realistic sugarcane production are destroyed by full mechanized cultivation (FMC), we investigated the differential structures and functions of soil bacterial and fungal communities by FMC ...

Abstract	To provide new insights into whether soil health and fertility in realistic sugarcane production are destroyed by full mechanized cultivation (FMC), we investigated the differential structures and functions of soil bacterial and fungal communities by FMC and conventional artificial cultivation (CAC) treatments in sugarcane fields. The results showed that the soil water, total phosphorus, available nitrogen, phosphorus, and potassium contents significantly increased, but soil bulk density and pH significantly decreased in the FMC treatment compared with the CAC treatment. The activities of soil enzymes such as β-glucosidase, aminopeptidase, and acid phosphatase changed irregularly. Compared with the CAC treatment, significantly higher β-glucosidase activity and significantly lower aminopeptidase and acid phosphatase activities were detected in the FMC treatment. The soil microbial biomass carbon and microbial biomass phosphorus (MBP) increased; in particular, significant increases in MBP were observed in the FMC treatment. In contrast, soil microbial biomass nitrogen significantly decreased in the FMC treatment. In addition, mechanized cultivation altered soil microbial community structures and their metabolite profiles in sugarcane fields. Although soil bacterial diversity and abundance were significantly reduced, fungal abundance was not significantly different in the FMC treatment. Moreover, compared with CAC treatments, Actinobacteria, Proteobacteria, Firmicutes, Acidothermus, Chujaibacter, Conexibacter, and Longimycelium, were significantly enriched in the FMC treatments. In addition, fungal community composition, only Gymnopilus at the genus level was significantly enriched in the FMC treatment. Eight differential metabolites were detected in soils of sugarcane fields between the FMC and CAC treatments and were also found in background (BG) soil. Among them, only organic acids and sugars were positively or negatively correlated with the abundance of different bacteria. Starch and sucrose metabolism were the most differentially expressed metabolic pathways between the FMC and CAC treatments. These results suggest that FMC did not destroy soil health and fertility in sugarcane fields.
Keywords	Acidothermus ; Firmicutes ; Gymnopilus ; Proteobacteria ; acid phosphatase ; aminopeptidases ; catenas ; community structure ; fungal communities ; fungi ; mechanization ; metabolism ; metabolites ; microbial biomass ; microbial carbon ; microbial nitrogen ; pH ; phosphorus ; potassium ; soil bacteria ; soil density ; soil quality ; soil water ; starch ; sucrose ; sugarcane ; total phosphorus ; Microbial community structure
Language	English
Dates of publication	2023-05
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	519608-5
ISSN	1872-6887 ; 0008-7769 ; 0341-8162
ISSN (online)	1872-6887 ; 0008-7769
ISSN	0341-8162
DOI	10.1016/j.catena.2023.107000
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Microtubule Affinity-Regulating Kinase 4 Promotes Oxidative Stress and Mitochondrial Dysfunction by Activating NF-κB and Inhibiting AMPK Pathways in Porcine Placental Trophoblasts

Liang Tian / Guangfan Liu / Ziqi Kang / Peishi Yan

Biomedicines, Vol 10, Iss 165, p

2022 Volume 165

Abstract: The aim of this investigation was to evaluate the role of MARK4 in the regulation of oxidative stress and mitochondrial dysfunction in pig placental trophoblasts and analyze the signaling pathways involved. In this study, we found that enhanced MARK4 ... ...

Abstract	The aim of this investigation was to evaluate the role of MARK4 in the regulation of oxidative stress and mitochondrial dysfunction in pig placental trophoblasts and analyze the signaling pathways involved. In this study, we found that enhanced MARK4 contributed to augmented oxidative stress in pig trophoblasts, as evidenced by decreased total antioxidant capacity (TAC); higher production of reactive oxygen species (ROS); elevated protein carbonylation; and reduced SOD, CAT, and GSH-PX activities. Further analyses revealed MARK4 impaired mitochondrial oxidative respiration in cultured trophoblasts, which was associated with reduced ATP content, decreased mitochondrial membrane potential, lower mitochondrial Complexes I and III activities, and down-regulated protein contents of subunits of complexes I, II, and V. At same time, mitochondrial biogenesis and structure were negatively altered by elevated MARK4. By antioxidant treatment with vitamin E (VE), oxidative stress along with impaired mitochondrial function induced by enhanced MARK4 were blocked. Furthermore, we found activation of AMPK signaling prevented MARK4 from blocking mitochondrial biogenesis and function in pig trophoblast cells. Finally, we demonstrated that the IKKα/NF-κB signal pathway was involved in MARK4 activated oxidative stress and mitochondrial dysfunction. Thus, these data suggest that MARK4 promotes oxidative stress and mitochondrial injury in porcine placental trophoblasts and can contribute to the developing of knowledge of pathological processes leading to mitochondrial dysfunction associated with excessive back-fat in the pig placenta and to the obesity-associated pregnant syndrome.
Keywords	MARK4 ; oxidative stress ; mitochondria ; NF-κB ; placenta ; AMPK ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preparation and sustained release of diatomite incorporated and Eudragit L100 coated hydroxypropyl cellulose/chitosan aerogel microspheres.

Sang, Yanan / Gao, Jie / Han, Xiaobing / Liang, Tian / Chen, Tao / Zhao, Yuan

International journal of biological macromolecules

2024 Volume 267, Issue Pt 1, Page(s) 131447

Abstract: The drug encapsulation efficiency, release rate and time, sustained release, and stimulus-response of carriers are very important for drug delivery. However, these always cannot obtained for the carrier with a single component. To improve the ... ...

Abstract	The drug encapsulation efficiency, release rate and time, sustained release, and stimulus-response of carriers are very important for drug delivery. However, these always cannot obtained for the carrier with a single component. To improve the comprehensive performance of chitosan-based carriers for 5-Fu delivery, diatomite-incorporated hydroxypropyl cellulose/chitosan (DE/HPC/CS) composite aerogel microspheres were fabricated for the release of 5-fluorouracil (5-Fu), and the release performance was regulated with the content of diatomite, pH value, and external coating material. Firstly, the 5-Fu loaded DE/HPC/CS composite aerogel microspheres and Eudragit L100 coated microspheres were prepared with cross-linking followed by freeze-drying, and characterized by SEM, EDS, FTIR, XRD, DSC, TG, and swelling. The obtained aerogel microspheres have a diameter of about 0.5 mm, the weight percentage of F and Si elements on the surface are 0.55 % and 0.78 % respectively. The glass transition temperature increased from 179 °C to 181 °C and 185 °C with the incorporation of DE and coating of Eudragit, and the equilibrium swelling percentage of DE/HPC/CS (1.5:3:2) carriers are 101.52 %, 45.27 %, 67.32 % at pH 1.2, 5.0, 7.4, respectively. Then, the effect of DE content on the drug loading efficiency of DE/HPC/CS@5-Fu was investigated, with the increase of DE content, the highest encapsulation efficiency was 82.6 %. Finally, the release behavior of DE incorporated and Eudragit L100 Coated microspheres were investigated under different pH values, and evaluated with four kinetic models. The results revealed that the release rate of 5-Fu decreased with the increase of DE content, sustained release with extending time and pH-responsive were observed for the Eudragit-coated aerogel microspheres.
MeSH term(s)	Chitosan/chemistry ; Microspheres ; Cellulose/chemistry ; Cellulose/analogs & derivatives ; Delayed-Action Preparations ; Fluorouracil/chemistry ; Fluorouracil/administration & dosage ; Drug Liberation ; Diatomaceous Earth/chemistry ; Polymethacrylic Acids/chemistry ; Drug Carriers/chemistry ; Hydrogen-Ion Concentration ; Gels/chemistry
Chemical Substances	Chitosan (9012-76-4) ; Cellulose (9004-34-6) ; methylmethacrylate-methacrylic acid copolymer (25086-15-1) ; Delayed-Action Preparations ; Fluorouracil (U3P01618RT) ; hydroxypropylcellulose (9XZ8H6N6OH) ; diatomite (68855-54-9) ; Diatomaceous Earth (61790-53-2) ; Polymethacrylic Acids ; Drug Carriers ; Gels
Language	English
Publishing date	2024-04-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.131447
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Article ; Online: Dynamics of Rabies Epidemics in Vampire Bats

Liang Tian / Juping Zhang

Complexity, Vol

2020 Volume 2020

Abstract: In order to study the transmission of rabies epidemics in vampire bats, we propose a mathematical model for vampire bat rabies virus. A threshold R0 is identified which determines the outcome of the disease. If R0<1, the disease-free equilibrium is ... ...

Abstract	In order to study the transmission of rabies epidemics in vampire bats, we propose a mathematical model for vampire bat rabies virus. A threshold R0 is identified which determines the outcome of the disease. If R0<1, the disease-free equilibrium is globally asymptotically stable, and if R0>1, the endemic equilibrium is globally asymptotically stable with certain conditions. Through the numerical simulation, the correctness of the theoretical results is verified. We carry out the sensitivity analysis of the parameters which provide a theoretical basis for preventing and controlling the transmission of bat rabies.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Detection of opinion leaders: Static vs. dynamic evaluation in online learning communities.

Kang, Min / Liang, Tian / Sun, Bing / Mao, Hong-Ying

Heliyon

2023 Volume 9, Issue 4, Page(s) e14844

Abstract: Opinion leaders play a critical role in maintaining the functioning of online communities. This study aims to detect opinion leaders in online learning communities by evaluating the influence of users within the community. We use Baidu Post Bar's Python ... ...

Abstract	Opinion leaders play a critical role in maintaining the functioning of online communities. This study aims to detect opinion leaders in online learning communities by evaluating the influence of users within the community. We use Baidu Post Bar's Python learning community as an example and employ the catastrophe progression method to statically evaluate the influence of users in three dimensions: user creativity, user posting quality, and user online interaction. Based on this, we introduce the dual-incentive control line to dynamically evaluate users' influence from 2016 to 2020 regarding speed change characteristics, thus scientifically detecting opinion leaders in online learning communities. Compared to the static evaluation method, the results show that our proposed dynamic evaluation method can more effectively reveal the dynamic development trend of users' influence, thus accurately detecting opinion leaders. Moreover, this "invisible" development trend is fully reflected in the setting of the dual-incentive control line.
Language	English
Publishing date	2023-03-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e14844
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Article ; Online: Impact of digital finance on energy-based carbon intensity: Evidence from mediating effects perspective.

Sun, Bing / Li, Jian / Zhong, Shen / Liang, Tian

Journal of environmental management

2022 Volume 327, Page(s) 116832

Abstract: This research measures energy-based carbon intensity based on energy consumption of 30 Chinese provinces and investigates the impact of digital finance. First, the baseline results were examined through panel data model. Second, we reveal the "black box" ...

Abstract	This research measures energy-based carbon intensity based on energy consumption of 30 Chinese provinces and investigates the impact of digital finance. First, the baseline results were examined through panel data model. Second, we reveal the "black box" system of digital finance and energy-based carbon intensity through mediating effects model. Third, by employed panel quantile regression model, we examine the heterogeneity of the effects of various factors under different carbon intensity quantile. The main quantitative results are as follows: (1) Digital finance shows significant sustainable effect, and its growth of 1% will reduce the carbon intensity by about 0.092%. (2) The intermediary effects of technological innovation and energy structure are -0.0663 and 0.007, respectively, accounting for 41.88% and 19.36% of the total effects. Both are significant transmission mechanisms. (3) When the carbon intensity in >0.9 quantile, digital finance shows a positive coefficient. On the contrary, the coefficient at <0.75 quantile is negative and its absolute value increases with the decrease of quantile. It shows that with the reduction of carbon intensity, the positive impact of digital finance gradually increases. (4) In the eastern, central and western regions, a 1% increase in digital finance will reduce the carbon intensity by 0.147%, 0.096% and 0.089% respectively. This research provides a reference for regional governments to use digital finance tools to promote sustainable development.
Language	English
Publishing date	2022-11-30
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2022.116832
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Article ; Online: Cement kiln co-processing promotes the redevelopment of industrially contaminated land in China: Spatio-temporal features and efficiency analysis.

Liang, Tian / Yang, Feihua / Ding, Aizhong / Li, Fasheng

The Science of the total environment

2022 Volume 817, Page(s) 152788

Abstract: The cleanup and redevelopment of industrially contaminated land are essential for sustainable urban development, both from economic and environmental perspectives. Remediation efforts in developed countries have incurred high decontamination costs and ... ...

Abstract	The cleanup and redevelopment of industrially contaminated land are essential for sustainable urban development, both from economic and environmental perspectives. Remediation efforts in developed countries have incurred high decontamination costs and administrative, monitoring, and enforcement requirements that are beyond the capabilities of many developing nations. Here, we reviewed the development of cement kiln co-processing of contaminated soils, a commonly used remediation strategy in China, and discussed the spatio-temporal features, benefits and efficiency of co-processing. Our results show that urbanization, the real estate market, and policies have impacts on the development of technology. By June 2021, cement kiln co-processing has disposed of approximately 2,633, 823 m
MeSH term(s)	China ; Environmental Pollutants/analysis ; Environmental Pollution/analysis ; India ; Metals, Heavy/analysis ; Soil ; Soil Pollutants/analysis
Chemical Substances	Environmental Pollutants ; Metals, Heavy ; Soil ; Soil Pollutants
Language	English
Publishing date	2022-01-04
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.152788
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