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  1. Article ; Online: Cold-stored Platelets for Bleeding Patients: Comment.

    Choi, Warren / Liang, Yafen

    Anesthesiology

    2022  Volume 138, Issue 2, Page(s) 218–219

    MeSH term(s) Humans ; Blood Platelets ; Hemorrhage ; Platelet Transfusion ; Blood Preservation ; Cold Temperature
    Language English
    Publishing date 2022-12-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004448
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  2. Article ; Online: Anesthesia management for total endovascular aortic arch repair: A case series.

    An, Sin Yeong / Webster, Tyler / Liang, Yafen

    Journal of clinical anesthesia

    2023  Volume 91, Page(s) 111261

    MeSH term(s) Humans ; Aorta, Thoracic/surgery ; Aortic Aneurysm, Thoracic/surgery ; Blood Vessel Prosthesis Implantation ; Endovascular Aneurysm Repair ; Anesthesia ; Endovascular Procedures/adverse effects ; Treatment Outcome ; Stents ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Letter
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2023.111261
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    Zs.A 2622: Show issues Location:
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  3. Article ; Online: Avoiding inadvertent subclavian artery puncture during central venous catheter placement.

    Nwokolo, OmoneleO / Liang, Yafen

    Journal of clinical anesthesia

    2021  Volume 75, Page(s) 110428

    MeSH term(s) Catheterization, Central Venous/adverse effects ; Central Venous Catheters/adverse effects ; Humans ; Punctures/adverse effects ; Subclavian Artery/diagnostic imaging ; Subclavian Artery/surgery
    Language English
    Publishing date 2021-07-30
    Publishing country United States
    Document type Letter
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2021.110428
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    Zs.A 2622: Show issues Location:
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  4. Article ; Online: Auto-triggering phenomenon secondary to the artificial pulsatility of continuous-Flow left ventricular assist device.

    Acosta, Ana / Obanor, Osamudiamen O / Liang, Yafen

    Journal of clinical anesthesia

    2022  Volume 80, Page(s) 110798

    MeSH term(s) Heart Failure/therapy ; Heart Ventricles ; Heart-Assist Devices/adverse effects ; Humans
    Language English
    Publishing date 2022-05-07
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2022.110798
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  5. Article ; Online: Current Concepts of Mechanical Circulatory Support: Are We Ready to Unload?

    Liang, Yafen / Gregoric, Igor / Kar, Biswajit / Eltzschig, Holger K

    Journal of the American College of Cardiology

    2022  Volume 80, Issue 18, Page(s) e155

    MeSH term(s) Humans ; Heart-Assist Devices ; Extracorporeal Membrane Oxygenation ; Cardiovascular System
    Language English
    Publishing date 2022-10-24
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.04.070
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    Zs.MO 196: Show issues

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  6. Article ; Online: Hypotension Prediction Index Guidance: Comment.

    Koepke, Elena / Liang, Yafen / Nwokolo, Omonele O

    Anesthesiology

    2021  Volume 134, Issue 6, Page(s) 972–973

    MeSH term(s) Arterial Pressure ; Humans ; Hypotension
    Language English
    Publishing date 2021-03-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000003758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Interplay of hypoxia-inducible factors and oxygen therapy in cardiovascular medicine.

    Liang, Yafen / Ruan, Wei / Jiang, Yandong / Smalling, Richard / Yuan, Xiaoyi / Eltzschig, Holger K

    Nature reviews. Cardiology

    2023  Volume 20, Issue 11, Page(s) 723–737

    Abstract: Mammals have evolved to adapt to differences in oxygen availability. Although systemic oxygen homeostasis relies on respiratory and circulatory responses, cellular adaptation to hypoxia involves the transcription factor hypoxia-inducible factor (HIF). ... ...

    Abstract Mammals have evolved to adapt to differences in oxygen availability. Although systemic oxygen homeostasis relies on respiratory and circulatory responses, cellular adaptation to hypoxia involves the transcription factor hypoxia-inducible factor (HIF). Given that many cardiovascular diseases involve some degree of systemic or local tissue hypoxia, oxygen therapy has been used liberally over many decades for the treatment of cardiovascular disorders. However, preclinical research has revealed the detrimental effects of excessive use of oxygen therapy, including the generation of toxic oxygen radicals or attenuation of endogenous protection by HIFs. In addition, investigators in clinical trials conducted in the past decade have questioned the excessive use of oxygen therapy and have identified specific cardiovascular diseases in which a more conservative approach to oxygen therapy could be beneficial compared with a more liberal approach. In this Review, we provide numerous perspectives on systemic and molecular oxygen homeostasis and the pathophysiological consequences of excessive oxygen use. In addition, we provide an overview of findings from clinical studies on oxygen therapy for myocardial ischaemia, cardiac arrest, heart failure and cardiac surgery. These clinical studies have prompted a shift from liberal oxygen supplementation to a more conservative and vigilant approach to oxygen therapy. Furthermore, we discuss the alternative therapeutic strategies that target oxygen-sensing pathways, including various preconditioning approaches and pharmacological HIF activators, that can be used regardless of the level of oxygen therapy that a patient is already receiving.
    MeSH term(s) Animals ; Humans ; Cardiovascular Diseases/drug therapy ; Hypoxia/therapy ; Oxygen/therapeutic use ; Oxygen/metabolism ; Oxygen Inhalation Therapy ; Gene Expression Regulation ; Mammals/metabolism
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-06-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2490375-9
    ISSN 1759-5010 ; 1759-5002
    ISSN (online) 1759-5010
    ISSN 1759-5002
    DOI 10.1038/s41569-023-00886-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6019: Show issues Location:
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    Zs.MG 98: Show issues

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  8. Article ; Online: Extending Our Role as Perioperative Physician in the Care of Undiagnosed Hypertensive Patients.

    Nwokolo, Omonele O / Patterson, Velvet / Liang, Yafen

    Anesthesia and analgesia

    2021  Volume 132, Issue 4, Page(s) e59–e60

    MeSH term(s) Anesthesiologists ; Cross-Sectional Studies ; Humans ; Hypertension/diagnosis ; Hypertension/epidemiology ; Quality Improvement
    Language English
    Publishing date 2021-03-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005400
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    Zs.MO 149: Show issues

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  9. Article ; Online: Cardiac ERAS Studies: Importance of Blinding.

    Markham, Travis H / Liang, Yafen / Zaki, John F

    Anesthesia and analgesia

    2021  Volume 132, Issue 5, Page(s) e79

    MeSH term(s) Analgesics, Opioid ; Anesthesia, Cardiac Procedures ; Cardiac Surgical Procedures ; Enhanced Recovery After Surgery
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2021-05-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005451
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  10. Article ; Online: Hypoxemia secondary to acute mitral regurgitation induced by systolic anterior motion of the mitral valve during lung transplantation.

    Morcous, Shaker / Kumar, Rishi / Patel, Manish / Liang, Yafen

    Journal of clinical anesthesia

    2021  Volume 75, Page(s) 110520

    MeSH term(s) Humans ; Hypoxia/etiology ; Lung Transplantation/adverse effects ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/surgery ; Systole
    Language English
    Publishing date 2021-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2021.110520
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