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Article ; Online: Prevalence of Malnutrition in Patients with Hepatocellular Carcinoma: A Comparative Study of GLIM Criteria, NRS2002, and PG-SGA, and Identification of Independent Risk Factors.

Tan, Shengqiang / Jiang, Jie / Qiu, Liulin / Liang, Yaohao / Meng, Jianyi / Tan, Ning / Xiang, Bangde

Nutrition and cancer

2024  Volume 76, Issue 4, Page(s) 335–344

Abstract: Aim: Malnutrition is prevalent in hepatocellular carcinoma (HCC) patients, linked to poor outcomes, necessitating early intervention. This study aimed to investigate malnutrition in HCC patients, assess Nutrition Risk Screening 2002 (NRS-2002) and ... ...

Abstract Aim: Malnutrition is prevalent in hepatocellular carcinoma (HCC) patients, linked to poor outcomes, necessitating early intervention. This study aimed to investigate malnutrition in HCC patients, assess Nutrition Risk Screening 2002 (NRS-2002) and Patient-Generated Subjective Global Assessment (PG-SGA)
Method: A cross-sectional retrospective study was conducted on 207 patients with HCC. Nutritional screening/assessment results and blood samples were collected within 72 h of admission. This study assessed the prevalence of malnutrition using the NRS-2002 and PG-SGA and retrospectively using the GLIM criteria. The performance of the screening tools was evaluated using kappa (
Results: Of the participants, 30.4% were at risk of malnutrition according to NRS-2002. The agreement between the NRS-2002 and GLIM criteria was substantial. The GLIM criteria and PG-SGA diagnosed malnutrition in 43 and 54.6% of the participants, respectively. Age, anemia, and ascites correlated with malnutrition in regression.
Conclusion: The GLIM criteria, along with NRS-2002 and PG-SGA, aid in diagnosing malnutrition in HCC patients. Recognizing risk factors improves accuracy, enabling timely interventions for better outcomes.
MeSH term(s) Humans ; Nutritional Status ; Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/epidemiology ; Prevalence ; Retrospective Studies ; Cross-Sectional Studies ; Leadership ; Nutrition Assessment ; Liver Neoplasms/complications ; Liver Neoplasms/epidemiology ; Malnutrition/diagnosis ; Malnutrition/epidemiology ; Malnutrition/etiology ; Risk Factors
Language English
Publishing date 2024-02-20
Publishing country United States
Document type Journal Article
ZDB-ID 424433-3
ISSN 1532-7914 ; 0163-5581
ISSN (online) 1532-7914
ISSN 0163-5581
DOI 10.1080/01635581.2024.2314317
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