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  1. Article: Non-alcoholic fatty liver disease increases the risk of cardiovascular disease in young adults and children: a systematic review and meta-analysis of cohort studies.

    Liao, Yan-Lin / Zhu, Gen-Yuan / Chang, Cheng

    Frontiers in cardiovascular medicine

    2024  Volume 10, Page(s) 1291438

    Abstract: Background and aims: It is uncertain if there is a link between non-alcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVD) in young adults and children. To evaluate the potential link between these two conditions, we conducted a ... ...

    Abstract Background and aims: It is uncertain if there is a link between non-alcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVD) in young adults and children. To evaluate the potential link between these two conditions, we conducted a systematic review and meta-analysis of cohort studies.
    Methods: A comprehensive search was conducted in PubMed, Web of Science and Embase in order to locate all relevant cohort studies published until August 2023. Random effects meta-analyses were conducted using the generic inverse variance method, with additional subgroup and sensitivity analyses. The Newcastle-Ottawa Scale was employed to evaluate the methodological quality.
    Results: Four cohort studies (eleven datasets) involving 10,668,189 participants were included in this meta-analysis. This meta-analysis demonstrated that NAFLD increases the risk of CVD in young adults and children (HR = 1.63, 95% CI: 1.46-1.82,
    Conclusion: Current evidence reveals that NAFLD is linked to an increased risk of major CVD (including CHD, MI, AF, CHF and stroke) in young adults and children. Further research is needed to strengthen this association and provide stronger evidence for primary prevention of CVD in young adults and children with NAFLD.
    Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, PROSPERO registration number: CRD42023457817.
    Language English
    Publishing date 2024-01-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1291438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ultra-narrowband dielectric metamaterial absorber with ultra-sparse nanowire grids for sensing applications.

    Liao, Yan-Lin / Zhao, Yan

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 1480

    Abstract: Due to their low losses, dielectric metamaterials provide an ideal resolution to construct ultra-narrowband absorbers. To improve the sensing performance, we present numerically a near-infrared ultra-narrowband absorber by putting ultra-sparse dielectric ...

    Abstract Due to their low losses, dielectric metamaterials provide an ideal resolution to construct ultra-narrowband absorbers. To improve the sensing performance, we present numerically a near-infrared ultra-narrowband absorber by putting ultra-sparse dielectric nanowire grids on metal substrate in this paper. The simulation results show that the absorber has an absorption rate larger than 0.99 with full width at half-maximum (FWHM) of 0.38 nm. The simulation field distribution also indicates that the ultra-narrowband absorption is originated from the low loss in the guided-mode resonance. Thanks to the ultra-narrow absorption bandwidths and the electric field mainly distributed out of the ultra-sparse dielectric nanowire grids, our absorber has a high sensitivity S of 1052 nm/RIU and a large figure of merit (FOM) of 2768 which mean that this ultra-narrowband absorber can be applied as a high-performance refractive index sensor.
    Language English
    Publishing date 2020-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-58456-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Graphene-based tunable ultra-narrowband mid-infrared TE-polarization absorber.

    Liao, Yan-Lin / Zhao, Yan

    Optics express

    2017  Volume 25, Issue 25, Page(s) 32080–32089

    Abstract: A graphene-based tunable ultra-narrowband mid-infrared TE-polarization absorber is proposed. The simulation results show that, the absorption peak can be tuned from 5.43896µm to 5.41418µm, by tuning the Fermi level of graphene from 0.2eV to 1.0eV. The ... ...

    Abstract A graphene-based tunable ultra-narrowband mid-infrared TE-polarization absorber is proposed. The simulation results show that, the absorption peak can be tuned from 5.43896µm to 5.41418µm, by tuning the Fermi level of graphene from 0.2eV to 1.0eV. The simulation results also show that the absorption bandwidth is less than 1.0nm and the absorption rate is more than 0.99 for TE-polarization (electric field is parallel to grating grooves) in the tuning wavelength range. The ultra-narrowband absorption mechanism is originated from the low power loss in the guided-mode resonance. The tuning function is mainly attributed to the change of the real part of the graphene's permittivity. This tunable ultra-narrowband mid-infrared absorber has potential applications in the tunable filtering and tunable coherent emission of thermal source.
    Language English
    Publishing date 2017-12-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.25.032080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Lithography-free wide-angle polarization-independent ultra-broadband absorber based on anti-reflection effect.

    Liao, Yan-Lin / Zhou, Junjie / Chen, Xiang / Wu, Jin / Chen, Zhenggen / Wu, Shan / Zhao, Yan

    Optics express

    2022  Volume 30, Issue 10, Page(s) 16847–16855

    Abstract: We propose a lithography-free wide-angle polarization-insensitive ultra-broadband absorber by using three pairs of tungsten (W) and calcium fluoride ( ... ...

    Abstract We propose a lithography-free wide-angle polarization-insensitive ultra-broadband absorber by using three pairs of tungsten (W) and calcium fluoride (CaF
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.459025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Naked cuticle inhibits wingless signaling in Drosophila wing development

    Wang, Rui / Xie, Hao / Yang, Lin / Wang, Ping / Chen, Meng-Meng / Wu, Hong-Yan / Liao, Yan-Lin / Wang, Ming-Ying / Wang, Qiang / Gong, Xiao-Xia / Cheng, Qian / Cheng, Lin / Xie, Fei-Yan / Bi, Cai-Li / Fang, Ming

    Biochemical and biophysical research communications. 2021 Oct. 22, v. 576 p.1-6

    2021  

    Abstract: Wnt signaling is one of the major signaling pathways that regulate cell differentiation, tissue patterning and stem cell homeostasis and its dysfunction causes many human diseases, such as cancer. It is of tremendous interests to understand how Wnt ... ...

    Abstract Wnt signaling is one of the major signaling pathways that regulate cell differentiation, tissue patterning and stem cell homeostasis and its dysfunction causes many human diseases, such as cancer. It is of tremendous interests to understand how Wnt signaling is regulated in a precise manner both temporally and spatially. Naked cuticle (Nkd) acts as a negative-feedback inhibitor for Wingless (Wg, a fly Wnt) signaling in Drosophila embryonic development. However, the role of Nkd remains controversial in later fly development, particularly on the canonical Wg pathway. In the present study, we show that nkd is essential for wing pattern formation, such that both gain and loss of nkd result in the disruption of Wg target expression in larvae stage and abnormal adult wing morphologies. Furthermore, we demonstrate that a thirty amino acid fragment in Nkd, identified previously in Wharton lab, is critical for the canonical Wg signaling, but is dispensable for Wg/planar cell polarity pathway. Putting aside the pleiotropic nature of nkd function, i.e. its role in the Decapentaplegic signaling, we conclude that Nkd universally inhibits the canonical Wg pathway across a life span of Drosophila development.
    Keywords Drosophila ; abnormal development ; cell polarity ; embryogenesis ; gene expression regulation ; imagos ; insect development ; insect larvae ; insect proteins ; mothers against decapentaplegic homolog proteins ; signal transduction ; transforming growth factor beta ; wings ; wnt proteins ; Development ; Naked cuticle ; Wingless ; Wnt signaling
    Language English
    Dates of publication 2021-1022
    Size p. 1-6.
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2021.08.077
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 71/706: Show issues
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  6. Article ; Online: Naked cuticle inhibits wingless signaling in Drosophila wing development.

    Wang, Rui / Xie, Hao / Yang, Lin / Wang, Ping / Chen, Meng-Meng / Wu, Hong-Yan / Liao, Yan-Lin / Wang, Ming-Ying / Wang, Qiang / Gong, Xiao-Xia / Cheng, Qian / Cheng, Lin / Xie, Fei-Yan / Bi, Cai-Li / Fang, Ming

    Biochemical and biophysical research communications

    2021  Volume 576, Page(s) 1–6

    Abstract: Wnt signaling is one of the major signaling pathways that regulate cell differentiation, tissue patterning and stem cell homeostasis and its dysfunction causes many human diseases, such as cancer. It is of tremendous interests to understand how Wnt ... ...

    Abstract Wnt signaling is one of the major signaling pathways that regulate cell differentiation, tissue patterning and stem cell homeostasis and its dysfunction causes many human diseases, such as cancer. It is of tremendous interests to understand how Wnt signaling is regulated in a precise manner both temporally and spatially. Naked cuticle (Nkd) acts as a negative-feedback inhibitor for Wingless (Wg, a fly Wnt) signaling in Drosophila embryonic development. However, the role of Nkd remains controversial in later fly development, particularly on the canonical Wg pathway. In the present study, we show that nkd is essential for wing pattern formation, such that both gain and loss of nkd result in the disruption of Wg target expression in larvae stage and abnormal adult wing morphologies. Furthermore, we demonstrate that a thirty amino acid fragment in Nkd, identified previously in Wharton lab, is critical for the canonical Wg signaling, but is dispensable for Wg/planar cell polarity pathway. Putting aside the pleiotropic nature of nkd function, i.e. its role in the Decapentaplegic signaling, we conclude that Nkd universally inhibits the canonical Wg pathway across a life span of Drosophila development.
    MeSH term(s) Animals ; Drosophila/genetics ; Drosophila/growth & development ; Drosophila/metabolism ; Drosophila Proteins/antagonists & inhibitors ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Feedback, Physiological ; Gene Expression Regulation, Developmental ; Signal Transduction ; Wnt Signaling Pathway ; Wnt1 Protein/antagonists & inhibitors
    Chemical Substances Drosophila Proteins ; Wnt1 Protein ; nkd protein, Drosophila ; wg protein, Drosophila
    Language English
    Publishing date 2021-08-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2021.08.077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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