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  1. Article ; Online: Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants.

    Licul-Kucera, Viktória / Frömel, Tobias / Kruså, Martin / van Wezel, Annemarie P / Knepper, Thomas P

    Chemosphere

    2023  Volume 339, Page(s) 139563

    Abstract: In this study the environmental fate of two novel trifluoromethoxy-substituted surfactants with respectively an ether or thioether linkage were investigated, of which the design aimed for less persistency and complete mineralization. Long-term microbial ... ...

    Abstract In this study the environmental fate of two novel trifluoromethoxy-substituted surfactants with respectively an ether or thioether linkage were investigated, of which the design aimed for less persistency and complete mineralization. Long-term microbial transformation studies under aerobic conditions in activated sludge-wastewater medium were performed for 126 days. A semi-closed experimental system with a trapping sorbent was selected to avoid losses of possible volatile transformation products (TPs). The changes in the concentration of the surfactants and their expected TPs were monitored by target analysis using liquid chromatography-tandem mass spectrometry. Significant decrease in the concentration of the surfactants was observed over the incubation period. The main detected TPs were short-chained carboxylic acids (CAs), including a CA with two fluorinated carbon atoms representing the last product prior to mineralization. High stability of these CAs and lack in the formation of inorganic fluoride over the incubation time was however observed. Consequently, unequivocal final mineralization of the investigated surfactants could not be confirmed. Regarding the mass balance, the total amount of detected substances achieved only 30-37% of the expected concentration at the end of the incubation time. The reason of the incomplete mass balance should be further investigated.
    MeSH term(s) Surface-Active Agents ; Biotransformation ; Mass Spectrometry ; Wastewater ; Sewage/chemistry ; Carboxylic Acids ; Water Pollutants, Chemical/analysis
    Chemical Substances Surface-Active Agents ; Wastewater ; Sewage ; Carboxylic Acids ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-07-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.139563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  2. Article ; Online: Interspecies comparison of metabolism of two novel prototype PFAS.

    Licul-Kucera, Viktória / Ragnarsdóttir, Oddný / Frömel, Tobias / van Wezel, Annemarie P / Knepper, Thomas P / Harrad, Stuart / Abou-Elwafa Abdallah, Mohamed

    Chemosphere

    2024  Volume 351, Page(s) 141237

    Abstract: As a result of proposed global restrictions and regulations on current-use per-and polyfluoroalkyl substances (PFAS), research on possible alternatives is highly required. In this study, phase I in vitro metabolism of two novel prototype PFAS in human ... ...

    Abstract As a result of proposed global restrictions and regulations on current-use per-and polyfluoroalkyl substances (PFAS), research on possible alternatives is highly required. In this study, phase I in vitro metabolism of two novel prototype PFAS in human and rat was investigated. These prototype chemicals are intended to be safer-by-design and expected to mineralize completely, and thus be less persistent in the environment compared to the PFAS available on the market. Following incubation with rat liver S9 (RL-S9) fractions, two main metabolites per initial substance were produced, namely an alcohol and a short-chain carboxylic acid. While with human liver S9 (HL-S9) fractions, only the short-chain carboxylic acid was detected. Beyond these major metabolites, two and five additional metabolites were identified at very low levels by non-targeted screening for the ether- and thioether-linked prototype chemicals, respectively. Overall, complete mineralization during the in vitro hepatic metabolism of these novel PFAS by HL-S9 and RL-S9 fractions was not observed. The reaction kinetics of the surfactants was determined by using the metabolite formation, rather than the substrate depletion approach. With rat liver enzymes, the formation rates of primary metabolite alcohols were at least two orders of magnitude higher than those of secondary metabolite carboxylic acids. When incubating with human liver enzymes, the formation rates of single metabolite carboxylic acids, were similar or smaller than those experienced in rat. It also indicates that the overall metabolic rate and clearance of surfactants are significantly higher in rat liver than in human liver. The maximum formation rate of the thioether congener exceeded 10-fold that of the ether in humans but were similar in rats. Overall, the results suggest that metabolism of the prototype chemicals followed a similar trend to those reported in studies of fluorotelomer alcohols.
    MeSH term(s) Rats ; Humans ; Animals ; Liver/metabolism ; Ethers ; Carboxylic Acids/metabolism ; Sulfides/metabolism ; Surface-Active Agents/metabolism ; Fluorocarbons/metabolism
    Chemical Substances Ethers ; Carboxylic Acids ; Sulfides ; Surface-Active Agents ; Fluorocarbons
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141237
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: The decomposition and emission factors of a wide range of PFAS in diverse, contaminated organic waste fractions undergoing dry pyrolysis.

    Sørmo, Erlend / Castro, Gabriela / Hubert, Michel / Licul-Kucera, Viktória / Quintanilla, Marjorie / Asimakopoulos, Alexandros G / Cornelissen, Gerard / Arp, Hans Peter H

    Journal of hazardous materials

    2023  Volume 454, Page(s) 131447

    Abstract: Current treatment options for organic waste contaminated with per- and polyfluoroalkyl substances (PFAS) are generally limited to incineration, composting or landfilling, all resulting in emissions. Dry pyrolysis is a promising emerging alternative to ... ...

    Abstract Current treatment options for organic waste contaminated with per- and polyfluoroalkyl substances (PFAS) are generally limited to incineration, composting or landfilling, all resulting in emissions. Dry pyrolysis is a promising emerging alternative to these practices, but there is uncertainty related to the fate of PFAS during this process. The present work first developed a robust method for the determination of PFAS in complex matrices, such as sewage sludge and biochar. Then, a mass balance was established for 56 different PFAS during full-scale pyrolysis (2-10 kg biochar hr
    Language English
    Publishing date 2023-04-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.131447
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  4. Article ; Online: The decomposition and emission factors of a wide range of PFAS in diverse, contaminated organic waste fractions undergoing dry pyrolysis

    Sørmo, Erlend / Castro, Gabriela / Hubert, Michel / Licul-Kucera, Viktória / Quintanilla, Marjorie / Asimakopoulos, Alexandros G. / Cornelissen, Gerard / Arp, Hans Peter H.

    Journal of Hazardous Materials. 2023 July 15, v. 454, p. 131447

    2023  , Page(s) 131447

    Abstract: Current treatment options for organic waste contaminated with per- and polyfluoroalkyl substances (PFAS) are generally limited to incineration, composting or landfilling, all resulting in emissions. Dry pyrolysis is a promising emerging alternative to ... ...

    Abstract Current treatment options for organic waste contaminated with per- and polyfluoroalkyl substances (PFAS) are generally limited to incineration, composting or landfilling, all resulting in emissions. Dry pyrolysis is a promising emerging alternative to these practices, but there is uncertainty related to the fate of PFAS during this process. The present work first developed a robust method for the determination of PFAS in complex matrices, such as sewage sludge and biochar. Then, a mass balance was established for 56 different PFAS during full-scale pyrolysis (2-10kg biochar hr⁻¹, 500-800 °C) of sewage sludges, food waste reject, garden waste and waste timber. PFAS were found in all wastes (56 to 3651ngg⁻¹), but pyrolysis resulted in a ≥96.9% removal. Residual PFAS (0.1-3.4ngg⁻¹) were detected in biochars obtained at temperatures up to 750 °C and were dominated by long chain PFAS. Emitted PFAS loads ranged from 0.01 to 3.1mg tonne⁻¹ of biochar produced and were dominated by short chain PFAS. Emissions made up <3% of total PFAS-mass in the wastes. Remaining uncertainties are mainly related to the presence of thermal degradation products in flue gas and condensation oils.
    Keywords biochar ; flue gas ; food waste ; garden residues ; pyrolysis ; sewage ; sewage sludge ; uncertainty ; organic waste ; PFAS ; method development ; emission factors ; mass balance
    Language English
    Dates of publication 2023-0418
    Size p. 131447
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version ; Use and reproduction
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.131447
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  5. Article ; Online: Application of (V)UV/O

    Krakkó, Dániel / Illés, Ádám / Licul-Kucera, Viktória / Dávid, Bence / Dobosy, Péter / Pogonyi, Andrea / Demeter, Attila / Mihucz, Victor G / Dóbé, Sándor / Záray, Gyula

    Chemosphere

    2021  Volume 275, Page(s) 130080

    Abstract: For the first time, high energy VUV photons and generation of ... ...

    Abstract For the first time, high energy VUV photons and generation of O
    MeSH term(s) Oxidation-Reduction ; Technology ; Ultraviolet Rays ; Waste Water ; Water Pollutants, Chemical/analysis ; Water Purification
    Chemical Substances Waste Water ; Water Pollutants, Chemical
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2021.130080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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