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  1. Article ; Online: Kaposi's sarcoma of the palate.

    Sakina, G / Liew, Y T

    QJM : monthly journal of the Association of Physicians

    2021  Volume 114, Issue 12, Page(s) 896–897

    MeSH term(s) Acquired Immunodeficiency Syndrome ; Humans ; Palate ; Sarcoma, Kaposi/diagnosis
    Language English
    Publishing date 2021-11-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcab264
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  2. Article ; Online: Cimetidine for recurrent respiratory papillomatosis in pregnancy as an alternative adjuvant treatment.

    Tan, Sien Hui / Ghauth, Sakina / Liew, Yew Toong / Abu Bakar, Zulkiflee

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 281, Issue 2, Page(s) 1053–1055

    Abstract: Background: We report the first case of cimetidine as an alternative adjuvant therapy in a pregnant woman with recurrent respiratory papillomatosis (RRP). A 40 year old woman at 19 week gestation presented with progressive hoarseness and shortness of ... ...

    Abstract Background: We report the first case of cimetidine as an alternative adjuvant therapy in a pregnant woman with recurrent respiratory papillomatosis (RRP). A 40 year old woman at 19 week gestation presented with progressive hoarseness and shortness of breath for 1 month. Flexible nasopharyngolaryngoscopy revealed multiple papillomatous lesions over both vocal cords and subglottic area obstructing 60% of her airway. She had previously been diagnosed with juvenile onset RRP at the age of 5 and underwent endoscopic clearance regularly every 6 months.
    Method: The patient was started on a trial of oral cimetidine at a dose of 30 mg/kg and responded well, eventually requiring endoscopic excision only after 2 years. Subsequently, she underwent in vitro fertilisation treatment and stopped taking her cimetidine. After undergoing endoscopic clearance of her papillomata under general anaesthesia, she restarted on cimetidine during her 2nd and 3rd trimester.
    Results: Ensuing follow-up demonstrated stable minimal papillomata lesions on her right inferior surface of her vocal cord with no recurrence on her left vocal cord and subglottic area.
    Conclusion: Cimetidine is generally safe and not known to be associated with any major teratogenic risks during pregnancy. RRP is postulated to worsen in pregnant women due to the increase in oestrogen levels during pregnancy. Hence, adjuvant therapy was imperative for our patient to reduce recurrent papillomata formation during her pregnancy. Larger scale studies are warranted to assess the use of long-term high-dose cimetidine in terms of efficacy and safety in pregnancy.
    MeSH term(s) Adult ; Female ; Humans ; Pregnancy ; Adjuvants, Immunologic/therapeutic use ; Cimetidine/therapeutic use ; Papillomavirus Infections/diagnosis ; Respiratory Tract Infections/diagnosis
    Chemical Substances Adjuvants, Immunologic ; Cimetidine (80061L1WGD)
    Language English
    Publishing date 2023-12-11
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08364-4
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  3. Article: Floor of Mouth Squamous Cell Carcinoma Presenting as an Abscess.

    Mohd Afandi, Mohd Farhan / Liew, Yew Toong

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2022  Volume 75, Issue 2, Page(s) 902–904

    Abstract: Oral squamous cell carcinoma (OSCC) is the most common malignancy encountered in oral cavity. Etiology is often multifactorial but strongly associated with chronic tobacco smoking, excessive alcohol consumption and tobacco chewing. Factors such as poor ... ...

    Abstract Oral squamous cell carcinoma (OSCC) is the most common malignancy encountered in oral cavity. Etiology is often multifactorial but strongly associated with chronic tobacco smoking, excessive alcohol consumption and tobacco chewing. Factors such as poor oral hygiene, ill-fitting dentures causing chronic mucosal irritation can also contribute to the cancer development. In recent years, studies shown association of HPV infections, especially subtypes 16 and 18 in malignant transformation of head and neck squamous cell carcinoma, as it present may change prognosis, outcomes and management strategies from HPV-negative OSCC. OSCC have variable presentation, and most of the patients tend to seek treatment at later stage of disease. The lesion may present as leukoplakia or erythroplakia and may be ulcerated with indurated base and rolled out edges. We describe an uncommon presentation of floor of mouth squamous cell carcinoma which presented as localized abscess.
    Language English
    Publishing date 2022-08-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-022-03128-8
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  4. Article ; Online: Laryngeal amyloidosis: a rare etiology of hoarseness.

    Ghauth, S / Toong, L Y / Sakina, G / Liew, Y T

    QJM : monthly journal of the Association of Physicians

    2022  Volume 114, Issue 12, Page(s) 889–890

    MeSH term(s) Amyloidosis/complications ; Amyloidosis/diagnosis ; Hoarseness/etiology ; Humans ; Laryngeal Diseases/complications ; Laryngeal Diseases/diagnosis
    Language English
    Publishing date 2022-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcab256
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  5. Article ; Online: Isolated cervical lymph node sarcoidosis: a diagnostic challenge of a case report.

    Lim, Chee Chean / Ghauth, Sakina / Liew, Yew Toong / Bakar, Mohd Zukiflee Bin Abu / Narayanan, Prepageran A L

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 280, Issue 2, Page(s) 925–927

    Abstract: Background: Sarcoidosis is a granulomatous disorder involving multi-systemic organs. Patients invariably have lung involvement but some may have extrapulmonary disease. Rarely, cervical lymphadenopathy is the only sign without mediastinal or pulmonary ... ...

    Abstract Background: Sarcoidosis is a granulomatous disorder involving multi-systemic organs. Patients invariably have lung involvement but some may have extrapulmonary disease. Rarely, cervical lymphadenopathy is the only sign without mediastinal or pulmonary abnormalities.
    Case presentation: We report a Malay male who complained of neck swelling exclusively. On imaging, multiple enlarged cervical lymph nodes deep to the sternocleidomastoid muscle were seen. An excision biopsy revealed non-caseating granulomas with epithelioid macrophages. Extensive investigations led to the diagnosis of isolated cervical lymph node sarcoidosis.
    Conclusions: Sarcoidosis can present as cervical lymphadenopathy alone, without mediastinal or lung disease. The presence of epithelioid granulomas on histopathology warrants the exclusion of other granulomatous diseases. Isolated cervical lymph node sarcoidosis is only diagnosed in the presence of consistent clinical and radiological findings. In this case, close monitoring for systemic sarcoidosis is important as it can manifest later in life.
    MeSH term(s) Humans ; Male ; Sarcoidosis/diagnosis ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/pathology ; Granuloma/diagnosis ; Granuloma/pathology ; Neck/pathology ; Lymphadenopathy/diagnostic imaging ; Lymphadenopathy/pathology
    Language English
    Publishing date 2023-01-02
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07808-7
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    Ul II Zs.50: Show issues Location:
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  6. Article: A Novel Methylene Blue Guided Neopharynx Closure and a Review of Essential Applications in Otolaryngology.

    Lim, Chee Chean / Liew, Yew Toong / Ghauth, Sakina / Bakar, Mohd Zukiflee Bin Abu / Narayanan, Prepageran

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2022  Volume 75, Issue 2, Page(s) 1255–1258

    Abstract: Methylene blue has many usages in the field of otolaryngology. We describe a preliminary finding of methylene blue guided neopharynx closure after total laryngectomy. This technique can potentially reduce the risk of pharyngocutaneous fistula and has not ...

    Abstract Methylene blue has many usages in the field of otolaryngology. We describe a preliminary finding of methylene blue guided neopharynx closure after total laryngectomy. This technique can potentially reduce the risk of pharyngocutaneous fistula and has not been described in the literature. It is also handy in assisting junior surgeons to perform modified Connell suture during neopharynx reconstruction. Concurrently, we reviewed other essential applications of methylene blue in otolaryngology.
    Language English
    Publishing date 2022-12-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-022-03192-0
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  7. Article: A Single Institution Cadaveric Study on Anatomical Variation of the Sublingual Gland Duct.

    Ab Rahim, Nurul Asma Che / Liew, Yew Toong / Ghauth, Sakina / Narayanan, Prepageran / Abu Bakar, Zulkiflee

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2022  Volume 75, Issue 2, Page(s) 347–351

    Abstract: The purpose of this study was to conduct a cadaveric dissection study on the anatomical variation of the sublingual (SLG) excretory ducts and dictate an improved understanding of the anatomical communication between the SLG duct and submandibular (SMG) ... ...

    Abstract The purpose of this study was to conduct a cadaveric dissection study on the anatomical variation of the sublingual (SLG) excretory ducts and dictate an improved understanding of the anatomical communication between the SLG duct and submandibular (SMG) ducts. This study is carried out by standardized dissection of anterior floor of mouth in 6 formalin-fixed adult cadavers in Silent Mentor Workshop University Malaya in August 2020. The cadavers had no trace of scars, adhesions, signs of trauma or operation. SMG duct opening was identified lateral to the lingual frenulum through a papilla in the floor of mouth behind the lower incisor tooth. A horizontal incision line was done over floor of mouth just lateral to the opening. SMG duct and SLG was traced and skeletonized. Any presence of major duct arising from the SLG and its communication with SMG duct were investigated. We found there are 3 patterns of SLG excretory duct variants; (1) One major (Bartholin's) duct which open independently at its own orifice adjacent to the orifice of the Wharton's duct of SMG. (2) One major (Bartholin's) duct which joined into the Wharton's duct of SMG. (3) Absent of a major duct arising from SLG. The overall mean diameter of SLG ducts were 1.3 ± 0.41 and the mean length of SLG ducts were 18.5 ± 6.55. The overall mean diameter of SMG ducts was 2.6 ± 0.74 and the mean length of SMG ducts were 46.5 ± 6.57. Excretory ductal system of SLG showed great variations, not only between the different cadavers but also within the different sides of the same cadaver. Awareness of potential anatomical variations can aid in the accurate diagnosis and treatment of patients with salivary gland pathology as well as help surgeons reveal potential risk factor and avoid complications during surgical procedures in the floor of mouth.
    Language English
    Publishing date 2022-11-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-022-03261-4
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  8. Article ; Online: Spontaneous Thyroid Haemorrhage: A Cause of Upper Airway Obstruction.

    Wong, Msl / Kanapaty, Y / Liew, Y T / Bakri, A

    Acute medicine

    2020  Volume 18, Issue 4, Page(s) 248–250

    Abstract: Background: Spontaneous thyroid haemorrhage is a very rare condition that is potentially life-threatening. We report an unusual case of spontaneous thyroid haemorrhage leading to airway compromise requiring urgent intervention. We highlight key clinical ...

    Abstract Background: Spontaneous thyroid haemorrhage is a very rare condition that is potentially life-threatening. We report an unusual case of spontaneous thyroid haemorrhage leading to airway compromise requiring urgent intervention. We highlight key clinical findings and management steps with comparison to similar cases in the literature.
    Case summary: An adult male presented with sudden anterior neck swelling and bruises on his neck and chest with hoarseness and dysphagia. Clinical assessment and CT scan revealed a thyroid haemorrhage with laryngopharyngeal, neck and chest haematoma. He was intubated for airway protection and given intravenous steroids and antibiotics. He was extubated well after 3 days.
    Conclusion: Careful prompt management of the patient's airway is of vital importance as worsening haematoma can lead to rapid airway compromise. Acute physicians should be aware of the clinical signs of thyroid haemorrhage, as this rare condition may present to the acute medical take.
    MeSH term(s) Adult ; Airway Obstruction/etiology ; Hematoma/complications ; Hematoma/diagnostic imaging ; Hemorrhage/complications ; Hemorrhage/diagnostic imaging ; Humans ; Male ; Thyroid Diseases/complications ; Thyroid Diseases/diagnosis ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-01-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1747-4892
    ISSN (online) 1747-4892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Dancing pharynx.

    Liew, Yew Toong / Junior, Andrew Charles Gomez / Bakri, Adzreil / Narayanan, Prepageran

    Ci ji yi xue za zhi = Tzu-chi medical journal

    2020  Volume 32, Issue 3, Page(s) 303–304

    Language English
    Publishing date 2020-04-01
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 2452925-4
    ISSN 1016-3190
    ISSN 1016-3190
    DOI 10.4103/tcmj.tcmj_245_19
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  10. Article ; Online: Acoustic neuroma with orofacial paresthesia: description of an atypical presentation.

    Lim, Chee Chean / Misron, Khairunnisak / Liew, Yew Toong / Wong, Eugene Hung Chih

    BMJ case reports

    2019  Volume 12, Issue 11

    Abstract: Acoustic neuroma (AN) usually manifests with asymmetric hearing loss, tinnitus, dizziness and sense of disequilibrium. About 10% of patients complain of atypical symptoms, which include facial numbness or pain and sudden onset of hearing loss. Patients ... ...

    Abstract Acoustic neuroma (AN) usually manifests with asymmetric hearing loss, tinnitus, dizziness and sense of disequilibrium. About 10% of patients complain of atypical symptoms, which include facial numbness or pain and sudden onset of hearing loss. Patients with atypical symptoms also tend to have larger tumours due to the delay in investigation. We report a particularly interesting case of a patient presented to us with numbness over her right hemifacial region after a dental procedure without significant acoustic and vestibular symptoms. Physical examination and pure tone audiometry revealed no significant findings but further imaging revealed a cerebellopontine angle mass. The changing trends with easier access to further imaging indicate that the presentation of patients with AN are also changing. Atypical symptoms which are persistent should raise clinical suspicion of this pathology among clinicians.
    MeSH term(s) Audiometry, Pure-Tone ; Cerebellar Neoplasms/complications ; Cerebellar Neoplasms/pathology ; Cerebellar Neoplasms/surgery ; Cerebellopontine Angle/pathology ; Facial Pain/etiology ; Facial Pain/physiopathology ; Female ; Hearing Loss/etiology ; Hearing Loss/physiopathology ; Humans ; Middle Aged ; Neuroma, Acoustic/complications ; Neuroma, Acoustic/pathology ; Neuroma, Acoustic/surgery ; Postoperative Period ; Treatment Outcome
    Language English
    Publishing date 2019-11-04
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-232275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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