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  1. Article ; Online: Seeking a fine balance between effective antithrombotic prophylaxis and safety drug profile in the elderly population: the special case of traumatic brain injury.

    Ganau, Laura / Syrmos, Nikolaos / Ligarotti, Gianfranco K I / Ganau, Mario

    Acta neurochirurgica

    2023  Volume 165, Issue 8, Page(s) 2215–2218

    MeSH term(s) Humans ; Aged ; Fibrinolytic Agents/adverse effects ; Brain Injuries, Traumatic/drug therapy ; Brain Injuries
    Chemical Substances Fibrinolytic Agents
    Language English
    Publishing date 2023-07-07
    Publishing country Austria
    Document type Letter
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05699-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.180: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Neurological recovery rate and minimal clinically important difference as metrics for assessing outcomes of decompressive surgery in patients with degenerative cervical myelopathy.

    Ganau, Laura / Ligarotti, Gianfranco K I / Ganau, Mario

    Acta neurochirurgica

    2022  Volume 164, Issue 12, Page(s) 3181–3183

    MeSH term(s) Humans ; Minimal Clinically Important Difference ; Benchmarking ; Spinal Cord Diseases/surgery ; Spondylosis/surgery ; Cervical Vertebrae/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-09-22
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05364-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.180: Show issues Location:
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  3. Article ; Online: Letter to the Editor Regarding "Burnout Among Neurosurgeons and Residents in Neurosurgery: A Systematic Review and Meta-Analysis of the Literature".

    Ganau, Laura / Ligarotti, Gianfranco K I / Ganau, Mario

    World neurosurgery

    2022  Volume 165, Page(s) 205

    MeSH term(s) Burnout, Professional ; Burnout, Psychological ; Humans ; Neurosurgeons ; Neurosurgery ; Neurosurgical Procedures
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review ; Comment
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2022.06.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article: The role of genetic and epigenetic factors in determining the risk of spinal fragility fractures: new insights in the management of spinal osteoporosis.

    Himič, Vratko / Syrmos, Nikolaos / Ligarotti, Gianfranco K I / Kato, So / Fehlings, Michael G / Ganau, Mario

    Quantitative imaging in medicine and surgery

    2023  Volume 13, Issue 11, Page(s) 7632–7645

    Abstract: Osteoporosis predisposes patients to spinal fragility fractures. Imaging plays a key role in the diagnosis and prognostication of these osteoporotic vertebral fractures (OVF). However, the current imaging knowledge base for OVF is lacking sufficient ... ...

    Abstract Osteoporosis predisposes patients to spinal fragility fractures. Imaging plays a key role in the diagnosis and prognostication of these osteoporotic vertebral fractures (OVF). However, the current imaging knowledge base for OVF is lacking sufficient standardisation to enable effective risk prognostication. OVF have been shown to be more prevalent in Caucasian patient cohorts in comparison to the Eastern Asian population. These population-based differences in risk for developing OVF suggest that there could be genetic and epigenetic factors that drive the pathogenesis of osteoporosis, low bone mineral density (BMD) and OVF. Several genetic loci have been associated with a higher vertebral fracture risk, although at varying degrees of significance. The present challenge is clarifying whether these associations are specific to vertebral fractures or osteoporosis more generally. Furthermore, these factors could be exploited for diagnostic interpretation as biomarkers [including novel long non-coding (lnc)RNAs, micro (mi)RNAs and circular (circ)RNAs]. The extent of methylation of genes, alongside post-translational histone modifications, have shown to affect several interlinked pathways that converge on the regulation of bone deposition and resorption, partially through their influence on osteoblast and osteoclast differentiation. Lastly, in addition to biomarkers, several exciting new imaging modalities could add to the established dual-energy X-ray absorptiometry (DXA) method used for BMD assessment. New technologies, and novel sequences within existing imaging modalities, may be able to quantify the quality of bone in addition to the BMD and bone structure; these are making progress through various stages of development from the pre-clinical sphere through to deployment in the clinical setting. In this mini review, we explore the literature to clarify the genetic and epigenetic factors associated with spinal fragility fractures and delineate the causal genes, pathways and interactions which could drive different risk profiles. We also outline the cutting-edge imaging modalities which could transform diagnostic protocols for OVF.
    Language English
    Publishing date 2023-10-08
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-23-513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Letter: A Scoping Review of Registered Clinical Studies on Mild Traumatic Brain Injury and Concussion (2000-2019).

    Ganau, Laura / Ligarotti, Gianfranco K I / Prisco, Lara / Ganau, Mario

    Neurosurgery

    2021  Volume 89, Issue 3, Page(s) E178–E179

    MeSH term(s) Brain Concussion/therapy ; Humans
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyab188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1424: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 539: Show issues

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  6. Article ; Online: Letter to the Editor. Randomized controlled trials on anterior versus posterior surgical decompression for degenerative cervical myelopathy.

    Ganau, Mario / Iqbal, Mohammad / Ligarotti, Gianfranco K I / Kato, So

    Journal of neurosurgery. Spine

    2021  Volume 34, Issue 6, Page(s) 957–958

    Language English
    Publishing date 2021-02-05
    Publishing country United States
    Document type Journal Article ; Letter
    ZDB-ID 2158643-3
    ISSN 1547-5646 ; 1547-5654
    ISSN (online) 1547-5646
    ISSN 1547-5654
    DOI 10.3171/2020.10.SPINE201895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.135 -Spine-: Show issues Location:
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  7. Article: Breakthrough in the assessment of cerebral perfusion and vascular permeability after brain trauma through the adoption of dynamic indocyanine green-enhanced near-infrared spectroscopy.

    Ganau, Mario / Iqbal, Mohammad / Ligarotti, Gianfranco K I / Syrmos, Nikolaos

    Quantitative imaging in medicine and surgery

    2020  Volume 10, Issue 11, Page(s) 2081–2084

    Language English
    Publishing date 2020-08-09
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-20-905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Efficacy and safety profiles of mechanical and pharmacological thromboprophylaxis.

    Ganau, Mario / Ligarotti, Gianfranco K I / Meloni, Marco / Chibbaro, Salvatore

    Annals of translational medicine

    2019  Volume 7, Issue Suppl 6, Page(s) S224

    Language English
    Publishing date 2019-10-11
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2019.08.44
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Predicting complexity of tumor removal and postoperative outcome in patients with high-grade gliomas.

    Ganau, Laura / Ligarotti, Gianfranco K I / Ganau, Mario

    Neurosurgical review

    2017  Volume 41, Issue 1, Page(s) 371–373

    MeSH term(s) Glioblastoma ; Glioma ; Humans ; Magnetic Resonance Spectroscopy ; Postoperative Period ; Treatment Outcome
    Language English
    Publishing date 2017-10-18
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-017-0921-1
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    Zs.A 1445: Show issues Location:
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  10. Article ; Online: Letter: Early Cranioplasty is Associated With Greater Neurological Improvement: A Systematic Review and Meta-Analysis.

    Ganau, Mario / Ligarotti, Gianfranco K I / Ganau, Laura / Prisco, Lara

    Neurosurgery

    2018  Volume 83, Issue 2, Page(s) E87–E89

    MeSH term(s) Decompressive Craniectomy ; Skull/surgery
    Language English
    Publishing date 2018-05-30
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyy205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1424: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 539: Show issues

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