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  1. Book ; Online ; E-Book: Small animal ophthalmic atlas and guide

    Lim, Christine C.

    2023  

    Author's details Christine C. Lim
    Keywords Veterinary ophthalmology ; Eye/Diseases/Treatment ; Domestic animals/Diseases
    Subject code 636.08977
    Language English
    Size 1 online resource (259 pages)
    Edition Second edition.
    Publisher Wiley Blackwell
    Publishing place Hoboken, New Jersey
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-119-80428-0 ; 1-119-80426-4 ; 9781119804253 ; 978-1-119-80428-4 ; 978-1-119-80426-0 ; 1119804256
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article ; Online: Identification of phase separating proteins associated with human disease.

    Lim, Christine M / González Díaz, Alicia

    Nature reviews. Molecular cell biology

    2023  Volume 25, Issue 1, Page(s) 5

    Language English
    Publishing date 2023-06-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2031313-5
    ISSN 1471-0080 ; 1471-0072
    ISSN (online) 1471-0080
    ISSN 1471-0072
    DOI 10.1038/s41580-023-00672-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5446: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 26: Show issues

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  3. Article ; Online: An In-House Developed Probiotics Database E-Reference Information for Healthcare Professionals.

    Goh, Adison / Budijono, Brigitta / Lim, Christine / Chew, Eng Hui / Yap, Kevin

    Studies in health technology and informatics

    2024  Volume 310, Page(s) 239–243

    Abstract: Currently available references provide evidence on efficacy of probiotics strains but exclude product-specific information, making it challenging for healthcare professionals (HCPs) to provide suitable probiotic recommendations to consumers. This study ... ...

    Abstract Currently available references provide evidence on efficacy of probiotics strains but exclude product-specific information, making it challenging for healthcare professionals (HCPs) to provide suitable probiotic recommendations to consumers. This study describes the development and evaluation of an online probiotics e-reference database to assist HCPs in delivering evidence-based recommendations on probiotics to consumers. The database currently consists of 556 clinical studies collated through PubMed literature search, 753 probiotic products from multiple retail stores in Singapore and 5708 unique product-study links. Users can search for probiotics based on indication, product or strain. Based on a pilot evaluation by 25 pharmacists practising in hospital and retail settings, 84% agreed that the database helped in assessing the efficacy of probiotic products. All (100%) found the database easy to navigate and most (96%) would continue to use the database as an evidence-based e-reference for probiotic information.
    MeSH term(s) Humans ; Health Personnel ; Pharmacists ; Databases, Factual ; Probiotics/therapeutic use ; Delivery of Health Care
    Language English
    Publishing date 2024-01-25
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI230963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Multiomic prediction of therapeutic targets for human diseases associated with protein phase separation.

    Lim, Christine M / González Díaz, Alicia / Fuxreiter, Monika / Pun, Frank W / Zhavoronkov, Alex / Vendruscolo, Michele

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 40, Page(s) e2300215120

    Abstract: The phenomenon of protein phase separation (PPS) underlies a wide range of cellular functions. Correspondingly, the dysregulation of the PPS process has been associated with numerous human diseases. To enable therapeutic interventions based on the ... ...

    Abstract The phenomenon of protein phase separation (PPS) underlies a wide range of cellular functions. Correspondingly, the dysregulation of the PPS process has been associated with numerous human diseases. To enable therapeutic interventions based on the regulation of this association, possible targets should be identified. For this purpose, we present an approach that combines the multiomic PandaOmics platform with the FuzDrop method to identify PPS-prone disease-associated proteins. Using this approach, we prioritize candidates with high PandaOmics and FuzDrop scores using a profiling method that accounts for a wide range of parameters relevant for disease mechanism and pharmacological intervention. We validate the differential phase separation behaviors of three predicted Alzheimer's disease targets (MARCKS, CAMKK2, and p62) in two cell models of this disease. Overall, the approach that we present generates a list of possible therapeutic targets for human diseases associated with the dysregulation of the PPS process.
    MeSH term(s) Humans ; Multiomics ; Proteins ; Alzheimer Disease/drug therapy ; Alzheimer Disease/genetics ; Calcium-Calmodulin-Dependent Protein Kinase Kinase
    Chemical Substances Proteins ; CAMKK2 protein, human (EC 2.7.11.17) ; Calcium-Calmodulin-Dependent Protein Kinase Kinase (EC 2.7.11.17)
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2300215120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1148: Show issues Location:
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  5. Article: Evaluation and Management of Neurogenic Thoracic Outlet Syndrome with an Overview of Surgical Approaches: A Comprehensive Review.

    Lim, Christine / Kavousi, Yasaman / Lum, Ying Wei / Christo, Paul J

    Journal of pain research

    2021  Volume 14, Page(s) 3085–3095

    Abstract: Neurogenic thoracic outlet syndrome (NTOS) represents a disorder believed to involve compression of one or more neurovascular elements as they exit the thoracic outlet. This comprehensive literature review will focus on the occurrence, classification, ... ...

    Abstract Neurogenic thoracic outlet syndrome (NTOS) represents a disorder believed to involve compression of one or more neurovascular elements as they exit the thoracic outlet. This comprehensive literature review will focus on the occurrence, classification, etiology, clinical presentation, diagnostic measures, and both nonoperative and operative therapies for NTOS. NTOS represents the most common subtype of thoracic outlet syndrome and can significantly impair quality of life. Botulinum toxin injection into the anterior scalene muscle, or even the middle scalene or pectoralis minor muscles, can reduce the symptoms of this syndrome. The best available evidence for botulinum toxin therapy to the cervicothoracic muscles supports the value of this treatment for reducing pain in the affected extremity, and for an approximate duration of 2 months or more. Surgical approaches and newer minimally invasive surgical approaches offer high rates of improvement in select centers.
    Language English
    Publishing date 2021-10-05
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S282578
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Small animal ophthalmic atlas and guide

    Lim, Christine C

    2015  

    Author's details Christine C. Lim
    MeSH term(s) Eye Diseases/veterinary ; Eye Diseases/diagnosis ; Animals, Domestic
    Language English
    Size xiii, 151 pages :, illustrations
    Document type Book
    ISBN 9781118689769 ; 1118689763
    Database Catalogue of the US National Library of Medicine (NLM)

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    Inter-library loan at ZB MED

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  7. Book: Small animal ophthalmic atlas and guide

    Lim, Christine C

    2015  

    Author's details Christine C. Lim
    MeSH term(s) Animals, Domestic ; Eye Diseases/diagnosis ; Eye Diseases/veterinary
    Keywords Eye/Diseases/Treatment ; Veterinary ophthalmology
    Language English
    Size XIII, 151 S, zahlr. Ill
    Publisher Wiley-Blackwell
    Publishing place Ames, Iowa u.a.
    Document type Book
    Note Literaturangaben
    ISBN 9781118689769 ; 1118689763
    Database Special collection on veterinary medicine and general parasitology

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  8. Article: Dynamic heterogeneous panel data analysis of tourism demand for Singapore

    Lim, Christine / Zhu, Liang

    Journal of travel and tourism marketing Vol. 34, No. 9 , p. 1224-1234

    2017  Volume 34, Issue 9, Page(s) 1224–1234

    Author's details Christine Lim and Liang Zhu
    Keywords Tourism demand modeling ; dynamic heterogeneous panels ; pooled mean group estimation ; long-run equilibrium relationship
    Language English
    Publisher Haworth Press
    Publishing place Binghamton, NY
    Document type Article
    ZDB-ID 1408990-7
    ISSN 1054-8408
    Database ECONomics Information System

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  9. Article ; Online: Dural puncture during lumbar epidural access in the setting of degenerative spondylolisthesis: case series and risk mitigation strategies.

    Sindhi, Vivek / Lim, Christine G / Khan, Anver / Pino, Carlos / Cohen, Steven P

    Regional anesthesia and pain medicine

    2021  Volume 46, Issue 11, Page(s) 992–996

    Abstract: Degenerative spondylolisthesis is a common back pathology in the general adult population. Patients with this condition may present for epidural steroid injection, epidural blood patch, or epidural analgesia. We report five patients with degenerative ... ...

    Abstract Degenerative spondylolisthesis is a common back pathology in the general adult population. Patients with this condition may present for epidural steroid injection, epidural blood patch, or epidural analgesia. We report five patients with degenerative spondylolisthesis who experienced inadvertent dural puncture during interlaminar epidural steroid injection attempts: four with intrathecal contrast spread or cerebrospinal backflow into the epidural needle and one with subdural contrast spread. Patients with degenerative spondylolisthesis may be at higher risk for dural puncture due to stretching of the dura and contraction of the epidural space at the translated spinal level. In the following report, we summarize the cases and suggest risk mitigation strategies for both chronic and acute pain physicians.
    MeSH term(s) Adult ; Analgesia, Epidural/adverse effects ; Blood Patch, Epidural ; Dura Mater/diagnostic imaging ; Humans ; Spinal Puncture ; Spondylolisthesis/diagnostic imaging ; Spondylolisthesis/surgery
    Language English
    Publishing date 2021-07-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2021-102963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2399: Show issues Location:
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  10. Article ; Online: Pathology in Practice.

    Roberts, Jordan K / de Linde Henriksen, Michala / Sharkey, Leslie / Lim, Christine C / Reilly, Christopher M

    Journal of the American Veterinary Medical Association

    2021  Volume 258, Issue 3, Page(s) 265–268

    MeSH term(s) Animals
    Language English
    Publishing date 2021-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.258.3.265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 423: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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