Article ; Online: Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow
Chemical communications. 2018 May 29, v. 54, no. 44 p.5606-5609
2018
Abstract: We report an acridium-based organic photocatalyst as an efficient replacement for iridium-based photocatalysts to oxidise boronic acid derivatives by a single electron process. Furthermore, we applied the developed catalytic system to the synthesis of ... ...
| Abstract | We report an acridium-based organic photocatalyst as an efficient replacement for iridium-based photocatalysts to oxidise boronic acid derivatives by a single electron process. Furthermore, we applied the developed catalytic system to the synthesis of four active pharmaceutical ingredients (APIs). A straightforward scale up approach using continuous flow photoreactors is also reported affording gram an hour throughput. |
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| Keywords | active pharmaceutical ingredients ; boronic acids ; photocatalysis ; photocatalysts |
| Language | English |
| Dates of publication | 2018-0529 |
| Size | p. 5606-5609. |
| Publishing place | The Royal Society of Chemistry |
| Document type | Article ; Online |
| ZDB-ID | 1472881-3 |
| ISSN | 1364-548X ; 1359-7345 ; 0009-241X |
| ISSN (online) | 1364-548X |
| ISSN | 1359-7345 ; 0009-241X |
| DOI | 10.1039/c8cc02169d |
| Database | NAL-Catalogue (AGRICOLA) |
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