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  1. Article: Four kinds of capping materials for controlling phosphorus and nitrogen release from contaminated sediment using a static simulation experiment

    Zhou, Zhenming / Lin, Canyang / Li, Shuwen / Liu, Shupo / Li, Fei / Yuan, Baoling

    Frontiers of environmental science & engineering. 2022 Mar., v. 16, no. 3

    2022  

    Abstract: We determined the effects of quartz sand (QS), water treatment plant sludge (WTPS), aluminum-based P-inactivation agent (Al-PIA), and lanthanum-modified bentonite (LMB) thin-layer capping on controlling phosphorus and nitrogen release from the sediment, ... ...

    Abstract We determined the effects of quartz sand (QS), water treatment plant sludge (WTPS), aluminum-based P-inactivation agent (Al-PIA), and lanthanum-modified bentonite (LMB) thin-layer capping on controlling phosphorus and nitrogen release from the sediment, using a static simulation experiment. The sediment in the experiment was sampled from Yundang Lagoon (Xiamen, Fujian Province, China), which is a eutrophic waterbody. The total phosphorus (TP), ammonium nitrogen (NH ₄⁺ -N), and total organic carbon (TOC) levels in the overlying water were measured at regular intervals, and the changes of different P forms in WTPS, Al-PIA, and sediment of each system were analyzed before and after the test. The average TP reduction rates of LMB, Al-PIA, WTPS, and QS were 94.82, 92.14, 86.88, and 10.68%, respectively, when the release strength of sediment TP was 2.26–9.19 mg/(m²·d) and the capping strength of the materials was 2 kg/m². Thin-layer capping of LMB, WTPS, and Al-PIA could effectively control P release from the sediment (P < 0.05). However, thin-layer capping of LMB, Al-PIA, and QS did not significantly reduce the release of ammonium N and organic matter (P > 0.05). Based on our results, LMB, Al-PIA, and WTPS thin-layer capping promoted the migration and transformation of easily released P in sediment. The P adsorbed by WTPS and Al-PIA mainly occurred in the form of NAIP.
    Keywords ammonium nitrogen ; bentonite ; eutrophication ; nitrogen ; phosphorus ; quartz ; sand ; sediment contamination ; sludge ; surface water ; total organic carbon ; total phosphorus ; water treatment ; China
    Language English
    Dates of publication 2022-03
    Size p. 29.
    Publishing place Higher Education Press
    Document type Article
    ZDB-ID 2662203-8
    ISSN 2095-221X ; 2095-2201
    ISSN (online) 2095-221X
    ISSN 2095-2201
    DOI 10.1007/s11783-021-1463-x
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7938: Show issues

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  2. Article: Development of a combined model incorporating clinical characteristics and magnetic resonance imaging features to enhance the predictive value of a prognostic model for locally advanced cervical cancer.

    Lin, Canyang / Yang, Fengling / Guo, Baoling / Xiao, Nan / Liao, Dongxia / Liu, Pengfei / Jiang, Yunshan / Li, Jiancheng / Ni, Xiaolei

    Frontiers in oncology

    2023  Volume 13, Page(s) 1284493

    Abstract: Objective: This study aimed to develop non-invasive predictive tools based on clinical characteristics and magnetic resonance imaging (MRI) features to predict survival in patients with locally advanced cervical cancer (LACC), thereby facilitating ... ...

    Abstract Objective: This study aimed to develop non-invasive predictive tools based on clinical characteristics and magnetic resonance imaging (MRI) features to predict survival in patients with locally advanced cervical cancer (LACC), thereby facilitating clinical decision-making.
    Methods: We conducted a retrospective analysis of clinical and MRI data from LACC patients who underwent radical radiotherapy at our center between September 2012 and May 2020. Prognostic predictors were identified using single-factor and multifactor Cox analyses. Clinical and MRI models were established based on relevant features, and combined models were created by incorporating MRI factors into the clinical model. The predictive performance of the models was evaluated using the area under the curve (AUC), consistency index (C-index), and decision curve analysis (DCA).
    Results: The study included 175 LACC patients. Multivariate Cox analysis revealed that patients with FIGO IIA-IIB stage, ECOG score 0-1, CYFRA 21-1<7.7 ng/ml, ADC ≥ 0.79 mm^2/s, and Kep ≥ 4.23 minutes had a more favorable survival prognosis. The clinical models, incorporating ECOG, FIGO staging, and CYFRA21-1, outperformed individual prognostic factors in predicting 5-year overall survival (AUC: 0.803) and 5-year progression-free survival (AUC: 0.807). The addition of MRI factors to the clinical model (AUC: 0.803 for 5-year overall survival) increased the AUC of the combined model to 0.858 (P=0.011). Similarly, the combined model demonstrated a superior predictive ability for 5-year progression-free survival, with an AUC of 0.849, compared to the clinical model (AUC: 0.807) and the MRI model (AUC: 0.673). Furthermore, the C-index of the clinical models for overall survival and progression-free survival were 0.763 and 0.800, respectively. Upon incorporating MRI factors, the C-index of the combined model increased to 0.826 for overall survival and 0.843 for progression-free survival. The DCA further supported the superior prognostic performance of the combined model.
    Conclusion: Our findings indicate that ECOG, FIGO staging, and CYFRA21-1 in clinical characteristics, as well as ADC and Kep values in MRI features, are independent prognostic factors for LACC patients undergoing radical radiotherapy. The combined models provide enhanced predictive ability in assessing the risk of patient mortality and disease progression.
    Language English
    Publishing date 2023-11-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1284493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Al-PHOSLOCK thin-layer capping to control phosphorus release from sediment: effect of hydraulic retention time and phosphorus migration/transformation mechanism

    Lin, Canyang / Li, Shuwen / Zhu, Bolin / Liu, Shupo / Li, Fei / Zhou, Zhenming / Li, Tao

    Journal of soils and sediments. 2021 June, v. 21, no. 6

    2021  

    Abstract: PURPOSE: This work aimed to (i) investigate the effect of hydraulic retention time (HRT) on controlling the release of phosphorus from sediment and (ii) interpret the phosphorus migration and transformation mechanism in the Al-PHOSLOCK thin-layer capping ...

    Abstract PURPOSE: This work aimed to (i) investigate the effect of hydraulic retention time (HRT) on controlling the release of phosphorus from sediment and (ii) interpret the phosphorus migration and transformation mechanism in the Al-PHOSLOCK thin-layer capping system. METHODS: A 35-day laboratory dynamic simulation experiment was conducted by applying the Al-PHOSLOCK thin-layer capping to evaluate the effect of HRT on interrupting the release of phosphorus from contaminated sediments. The total phosphorus (TP), inorganic phosphorus (IP), organic phosphorus (OP), non-apatite inorganic phosphorus (NAIP), and apatite phosphorus (AP) were identified as different phosphorus species and analyzed during the experiment to further elucidate the migration and transformation of phosphorus. RESULTS AND DISCUSSION: The release of phosphorus from contaminated sediment was successfully suppressed by the Al-PHOSLOCK capping layer with an efficiency of higher than 90%. The HRT exerted a dual role on phosphorus controlling: at low HRT, slight water flow facilitated phosphorus migrating out from sediment and diffusing to the overlying water; at high HRT, the migration of phosphorus from overlying water back to sediment was strengthened. It was demonstrated that the phosphorus release was effectively controlled by the Al-PHOSLOCK thin-layer capping under different HRT conditions (static, 0.5 d, 1.0 d, and 3.0 d). The mechanism of phosphorus migration and transformation in the Al-PHOSLOCK thin-layer capping system was elucidated, including three significant stages of physical interception, adsorption, and capture/hold/transform process. CONCLUSION: This study verified the good capacity of the Al-PHOSLOCK capping system for controlling the release of sediment phosphorus under different HRT. Therefore, it was expected to be a promising approach in the handling of water eutrophication.
    Keywords adsorption ; apatite ; eutrophication ; inorganic phosphorus ; organic phosphorus ; sediment contamination ; sediments ; total phosphorus ; water flow
    Language English
    Dates of publication 2021-06
    Size p. 2474-2482.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2050898-0
    ISSN 1614-7480 ; 1439-0108
    ISSN (online) 1614-7480
    ISSN 1439-0108
    DOI 10.1007/s11368-021-02958-3
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7702: Show issues

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  4. Article ; Online: The effect of secondary capping on the control of phosphorus release from sediment by activated thin-layer capping with Al-PIA.

    Zhu, Bolin / Li, Shuwen / Lin, Canyang / Liu, Shupo / Li, Fei / Zhou, Zhenming

    Environmental science and pollution research international

    2021  Volume 28, Issue 14, Page(s) 18062–18069

    Abstract: It is well-known that the activated thin-layer capping covering by secondary capping of contaminated sediment poses a threat to the inactivation of activated material. In this study, the static simulation experiment was conducted to study the effect of ... ...

    Abstract It is well-known that the activated thin-layer capping covering by secondary capping of contaminated sediment poses a threat to the inactivation of activated material. In this study, the static simulation experiment was conducted to study the effect of secondary capping thickness by sediment on the control of TP release from the sediment by aluminum-based P-inactivation agent (Al-PIA), and to propose the phosphorus adsorption pathway of Al-PIA. The results showed that Al-PIA could effectively reduce the release of phosphorus pollutants from the sediment at the capping intensity of 2 kg/m
    MeSH term(s) Adsorption ; Aluminum ; Geologic Sediments ; Phosphorus ; Water Pollutants, Chemical/analysis
    Chemical Substances Water Pollutants, Chemical ; Phosphorus (27YLU75U4W) ; Aluminum (CPD4NFA903)
    Language English
    Publishing date 2021-01-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-020-11828-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  5. Article ; Online: SEC61G overexpression and DNA amplification correlates with prognosis and immune cell infiltration in head and neck squamous cell carcinoma.

    Lu, Tianzhu / Chen, Yiping / Gong, Xiaochang / Guo, Qiaojuan / Lin, Canyang / Luo, Qingfeng / Tu, Ziwei / Pan, Jianji / Li, Jingao

    Cancer medicine

    2021  Volume 10, Issue 21, Page(s) 7847–7862

    Abstract: Background: The SEC61 translocon gamma subunit (SEC61G) is a component of the SEC61 complex, which import protein into the endoplasmic reticulum. However, the correlation between SEC61G and disease prognosis in head and neck squamous cell carcinoma ( ... ...

    Abstract Background: The SEC61 translocon gamma subunit (SEC61G) is a component of the SEC61 complex, which import protein into the endoplasmic reticulum. However, the correlation between SEC61G and disease prognosis in head and neck squamous cell carcinoma (HNSCC) remains unclear.
    Methods: SEC61G expression was analyzed using publicly available datasets. The association between SEC61G and disease prognosis was evaluated. SEC61G methylation and copy number variation were investigated and gene set enrichment analysis and gene ontology analyses identified SEC61G-associated functions. We also investigated the correlation between SEC61G and immune cell infiltration. Finally, immunohistochemistry was used to detect SEC61G expression in oropharyngeal carcinoma.
    Results: SEC61G was overexpressed in pan-cancers, including HNSCC, and negatively correlated with overall survival (OS) (p < 0.001 for TCGA-HNSCC and p = 0.019 for GSE65858). Moreover, SEC61G was an independent prognostic factor for OS in TCGA and GSE65858 [hazard ratio (HR) = 1.80, 95% CI: 1.35-2.39, p < 0.001; HR = 1.87, 95% CI: 1.14-3.07, p = 0.013, respectively). SEC61G DNA amplification (9.66% of patients) was significantly associated with poor OS (p = 0.034). SEC61G overexpression and DNA amplification negatively correlated with B cell (p < 0.001), CD8
    Conclusions: SEC61G is overexpressed in HNSCC and is an independent prognostic factor for OS. SEC61G DNA amplification contributes to overexpression and poor outcome. Interestingly, SEC61G correlates with immune cell infiltration in HNSCC. These findings suggest that SEC61G is a potential broad-spectrum biomarker for prognosis in HNSCC.
    MeSH term(s) DNA Copy Number Variations ; DNA Methylation ; Female ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/genetics ; Head and Neck Neoplasms/immunology ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Immunohistochemistry ; Male ; Middle Aged ; Nucleic Acid Amplification Techniques ; Prognosis ; Progression-Free Survival ; SEC Translocation Channels/genetics ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Squamous Cell Carcinoma of Head and Neck/genetics ; Squamous Cell Carcinoma of Head and Neck/immunology ; Up-Regulation
    Chemical Substances Immune Checkpoint Inhibitors ; SEC Translocation Channels ; SEC61G protein, human
    Language English
    Publishing date 2021-09-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.4301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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