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  1. Article ; Online: Cardiac events after using clarithromycin for anti-Helicobacter pylori therapy in patients with coronary artery disease.

    Lin, Cheng-Kuan / Lee, Tzong-Hsi / Liao, Pen-Chih / Lin, Cheng-Lu

    Medicine

    2023  Volume 102, Issue 45, Page(s) e35922

    Abstract: Clarithromycin is an antibiotic commonly used to treat Helicobacter pylori infections. The US Food and Drug Administration (FDA) advises caution before prescribing clarithromycin to patients with cardiac diseases. This study aimed to evaluate cardiac ... ...

    Abstract Clarithromycin is an antibiotic commonly used to treat Helicobacter pylori infections. The US Food and Drug Administration (FDA) advises caution before prescribing clarithromycin to patients with cardiac diseases. This study aimed to evaluate cardiac events after anti-H pylori treatment in patients with coronary artery disease. A retrospective 5-year study was conducted on outpatients who received anti-H pylori therapy. Among the 7855 patients receiving therapy, 228 patients (2.9%) underwent angiography with coronary artery disease before therapy, and 193 patients received clarithromycin. Clarithromycin users seemed not to be at risk for cardiac events as compared with non-clarithromycin users at 3 months (4.7% vs 2.9%, P = .63) and 1 year (10.9% vs 5.7%, P = .35). Neither life-threatening dysrhythmia nor cardiac death was noted. The risk factors for cardiac events within 3 months after therapy were smoker (OR:5.38, 95% CI:1.39-20.78), and events within 1 year were smoker (OR:3.8, 95% CI:1.41-10.22), and diabetes mellitus (OR:5.68, 95% CI:1.9-16.98). Among patients with coronary artery disease who received anti-H pylori therapy, short-term cardiac events did not increase in clarithromycin users but should be considered in diabetic and smoking patients.
    MeSH term(s) Humans ; Anti-Bacterial Agents/adverse effects ; Clarithromycin/adverse effects ; Coronary Artery Disease/etiology ; Drug Therapy, Combination ; Helicobacter Infections/complications ; Helicobacter Infections/drug therapy ; Helicobacter pylori ; Retrospective Studies
    Chemical Substances Anti-Bacterial Agents ; Clarithromycin (H1250JIK0A)
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Gastric peroral endoscopic pyloromyotomy for refractory diabetic gastroparesis: First case report in Taiwan.

    Lin, Cheng-Lu / Chen, Kuan-Chih / Wu, Jiann-Ming / Chung, Chen-Shuan

    Asian journal of surgery

    2019  Volume 42, Issue 5, Page(s) 641–643

    MeSH term(s) Adult ; Diabetes Complications ; Female ; Gastroparesis/etiology ; Gastroparesis/surgery ; Gastroscopy/methods ; Humans ; Pyloromyotomy/methods ; Taiwan ; Treatment Outcome
    Language English
    Publishing date 2019-02-23
    Publishing country China
    Document type Case Reports ; Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2019.01.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
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  3. Article: Efficacy and safety of gastric peroral endoscopic myotomy (G-POEM) for refractory gastroparesis: 3-year follow up results.

    Chung, Chen-Shuan / Huang, Tien-Yu / Lin, Cheng-Lu / Chiang, Chen-Han / Chen, Kuan-Chih / Wu, Jiann-Ming / Chen, Kuo-Hsin / Lee, Tzong-Hsi / Lin, Cheng-Kuan / Wang, Hisu-Po

    Journal of the Formosan Medical Association = Taiwan yi zhi

    2021  Volume 121, Issue 7, Page(s) 1334–1341

    Abstract: Background/purpose: Gastroparesis is a common but easily overlooked disease. Gastric peroral endoscopic myotomy (G-POEM) is one of the third-space endoscopy techniques to treat gastroparesis. In this study, we aimed to evaluate the efficacy and safety ... ...

    Abstract Background/purpose: Gastroparesis is a common but easily overlooked disease. Gastric peroral endoscopic myotomy (G-POEM) is one of the third-space endoscopy techniques to treat gastroparesis. In this study, we aimed to evaluate the efficacy and safety of G-POEM for patients with refractory gastroparesis.
    Methods: Between December 2017 and 2020, we consecutively enrolled patients with gastroparesis who failed after the administration of several kinds of medication and repeated admission for nutritional support. All patients underwent gastric emptying scintigraphy and answered a questionnaire on Gastroparesis Cardinal Symptom Index (GCSI). Demographic data, endoscopic procedure, and post procedural outcome were analyzed.
    Results: A total of 11 (9 women and 2 men) patients with refractory gastroparesis (nine with diabetes mellitus, one systemic lupus erythematosus, and one idiopathic) were enrolled. The mean (±standard deviation (SD)) procedure time was 61.82 (±18.99) min with technical and clinical success rates of 100% and 81.82%, respectively. A statistically significant improvement was observed in the clinical severity (mean GCSI score 36.00 vs. 14.73, p < 0.0001) and gastric emptying time (mean T
    Conclusion: G-POEM is an efficient and safe pylorus-directed endoscopic therapy for refractory gastroparesis with promising results.
    MeSH term(s) Esophageal Achalasia/complications ; Esophageal Sphincter, Lower ; Female ; Follow-Up Studies ; Gastroparesis/diagnosis ; Gastroparesis/etiology ; Gastroparesis/surgery ; Humans ; Male ; Pyloromyotomy/adverse effects ; Pyloromyotomy/methods ; Pylorus/surgery ; Treatment Outcome
    Language English
    Publishing date 2021-10-19
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2096659-3
    ISSN 1876-0821 ; 0929-6646
    ISSN (online) 1876-0821
    ISSN 0929-6646
    DOI 10.1016/j.jfma.2021.08.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1041: Show issues Location:
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  4. Article ; Online: Importance of tissue acquisition in gastric submucosal tumor with unusual EUS features.

    Lin, Cheng-Lu / Chen, Kuan-Chih / Lin, Cheng-Kuan / Tsai, Chien-Chen / Lee, Tzong-Hsi / Chung, Chen-Shuan

    Gastrointestinal endoscopy

    2019  Volume 89, Issue 6, Page(s) 1252–1254

    MeSH term(s) Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/secondary ; Aged ; Cecal Neoplasms/pathology ; Cecal Neoplasms/surgery ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery ; Endosonography ; Female ; Humans ; Pyloric Antrum/diagnostic imaging ; Pyloric Antrum/pathology ; Sigmoid Neoplasms/diagnostic imaging ; Sigmoid Neoplasms/secondary ; Stomach Neoplasms/diagnostic imaging ; Stomach Neoplasms/secondary
    Language English
    Publishing date 2019-02-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2019.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 283: Show issues Location:
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    Zs.MO 519: Show issues

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  5. Article ; Online: Clinical benefits from endoscopy screening of esophageal second primary tumor for head and neck cancer patients: Analysis of a hospital-based registry.

    Chung, Chen-Shuan / Lo, Wu-Chia / Chen, Kuan-Chih / Lin, Cheng-Lu / Wen, Ming-Hsun / Hsieh, Chen-Hsi / Lin, Shih-Chiang / Liao, Li-Jen

    Oral oncology

    2019  Volume 96, Page(s) 27–33

    Abstract: Objectives: Esophageal second primary tumors (SPTs) in head and neck cancer (HNC) patients is not uncommon. The impact of image-enhanced endoscopy (IEE) screening for esophageal SPT on the outcome of HNC patients has not been well clarified.: Methods ... ...

    Abstract Objectives: Esophageal second primary tumors (SPTs) in head and neck cancer (HNC) patients is not uncommon. The impact of image-enhanced endoscopy (IEE) screening for esophageal SPT on the outcome of HNC patients has not been well clarified.
    Methods and methods: Patients with malignancies of the head and neck region and esophagus were recruited from a hospital-based cancer registry between July 2000-December 2016. IEE screening included magnifying endoscopy with narrow-band imaging and chromoendoscopy with Lugol's solution. Biopsied specimens with revised Vienna classification categories 1 and 2 were defined as group I, and those with categories 3 to 5 were defined as group II. The Kaplan-Meier estimate and Cox regression model were used for survival analysis.
    Results: Totally 1577 HNC and 501 esophageal cancer patients were enrolled. The 5-year overall survival (OS) rates of stage I/II HNC, stage III/IV HNC and esophageal cancer patients were 58%, 29%, and 8%, respectively (p < 0.01). The 5-year OS rate of HNC patients with negative IEE results was higher than that of HNC patients without IEE screening, followed by IEE screening groups I, II and esophageal cancer patients (44% vs. 39% vs. 35% vs. 11% vs. 8%, respectively, p for trend <0.01). Among advanced HNC patients, those who received IEE screening had a trend of better prognosis than those without screening (5-year OS rate of 31% vs. 28%, p = 0.17).
    Conclusions: IEE screening for esophageal SPTs is helpful in risk stratification and prognosis prediction for HNC patients. Routine IEE screening is recommended in HNC patients.
    MeSH term(s) Early Detection of Cancer ; Endoscopy/methods ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/secondary ; Female ; Head and Neck Neoplasms/complications ; Head and Neck Neoplasms/mortality ; Humans ; Male ; Middle Aged ; Neoplasms, Second Primary ; Registries ; Survival Analysis
    Language English
    Publishing date 2019-07-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2019.06.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4869: Show issues Location:
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    Zs.A 456: Show issues Location:
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  6. Article: Investigation of silicon on insulator fabricated by two-step O+ implantation

    Wei, Xing / Xue, ZhongYing / Wu, AiMin / Wang, Xiang / Li, XianYuan / Ye, Fei / Chen, Jie / Chen, Meng / Zhang, Bo / Lin, ChengLu / Zhang, Miao / Wang, Xi

    Chinese science bulletin Kexue tongbao.. 2011 Feb., v. 56, no. 4-5

    2011  

    Abstract: In this paper, we investigated the dose window of forming a continuous buried oxide (BOX) layer by single implantation at the implantation energy of 200 keV. Then, an improved two-step implantation process with second implantation dose of 3×1015 cm−2 was ...

    Abstract In this paper, we investigated the dose window of forming a continuous buried oxide (BOX) layer by single implantation at the implantation energy of 200 keV. Then, an improved two-step implantation process with second implantation dose of 3×1015 cm−2 was developed to fabricate high quality separation by implanted oxygen (SIMOX) silicon on insulator (SOI) wafers. Compared with traditional single implantation, the implantation dose is reduced by 18.2%. In addition, the thickness and uniformity of the BOX layers were evaluated by spectroscopic ellipsometry. Defect-free top Si as well as atomic-scale sharp top Si/buried oxide interfaces were observed by transmission electron microscopy, indicating a high crystal quality and a perfect structure of the SOI fabricated by two step implantation. The top Si/BOX interface morphology of the SOI wafers fabricated by single or two-step implantation was also investigated by atomic force microscopy.
    Keywords atomic force microscopy ; energy ; oxygen ; silicon ; transmission electron microscopy
    Language English
    Dates of publication 2011-02
    Size p. 444-448.
    Publishing place Springer-Verlag
    Document type Article
    ZDB-ID 1021576-1
    ISSN 1861-9541 ; 1001-6538 ; 0250-7862
    ISSN (online) 1861-9541
    ISSN 1001-6538 ; 0250-7862
    DOI 10.1007/s11434-011-4382-6
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Investigation of silicon on insulator fabricated by two-step O+ implantation

    Wei, Xing / Xue, ZhongYing / Wu, AiMin / Wang, Xiang / Li, XianYuan / Ye, Fei / Chen, Jie / Chen, Meng / Zhang, Bo / Lin, ChengLu / Zhang, Miao / Wang, Xi

    Chinese science bulletin Kexue tongbao

    Volume v. 56,, Issue no. 4

    Abstract: In this paper, we investigated the dose window of forming a continuous buried oxide (BOX) layer by single implantation at the implantation energy of 200 keV. Then, an improved two-step implantation process with second implantation dose of 3×1015 cm−2 was ...

    Abstract In this paper, we investigated the dose window of forming a continuous buried oxide (BOX) layer by single implantation at the implantation energy of 200 keV. Then, an improved two-step implantation process with second implantation dose of 3×1015 cm−2 was developed to fabricate high quality separation by implanted oxygen (SIMOX) silicon on insulator (SOI) wafers. Compared with traditional single implantation, the implantation dose is reduced by 18.2%. In addition, the thickness and uniformity of the BOX layers were evaluated by spectroscopic ellipsometry. Defect-free top Si as well as atomic-scale sharp top Si/buried oxide interfaces were observed by transmission electron microscopy, indicating a high crystal quality and a perfect structure of the SOI fabricated by two step implantation. The top Si/BOX interface morphology of the SOI wafers fabricated by single or two-step implantation was also investigated by atomic force microscopy.
    Keywords transmission electron microscopy ; oxygen ; atomic force microscopy ; silicon ; energy
    Language English
    Document type Article
    ISSN 1001-6538
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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