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Article ; Online: Epidemiology Evidence for Health Effects of 150 per- and Polyfluoroalkyl Substances: A Systematic Evidence Map.

Radke, Elizabeth G / Wright, J Michael / Christensen, Krista / Lin, Cynthia J / Goldstone, Alexandra E / Lemeris, Courtney / Thayer, Kristina A

Environmental health perspectives

2022 Volume 130, Issue 9, Page(s) 96003

Abstract: Background: Per- and polyfluoroalkyl substances (PFAS) comprise a large class of chemicals with widespread use and persistence in the environment and in humans; however, most of the epidemiology research has focused on a small subset.: Objectives: ... ...

Abstract	Background: Per- and polyfluoroalkyl substances (PFAS) comprise a large class of chemicals with widespread use and persistence in the environment and in humans; however, most of the epidemiology research has focused on a small subset. Objectives: The aim of this systematic evidence map (SEM) is to summarize the epidemiology evidence on approximately 150 lesser studied PFAS prioritized by the EPA for tiered toxicity testing, facilitating interpretation of those results as well as identification of priorities for risk assessment and data gaps for future research. Methods: The Populations, Exposure, Comparators, and Outcomes (PECO) criteria were intentionally broad to identify studies of any health effects in humans with information on associations with exposure to the identified PFAS. Systematic review methods were used to search for literature that was screened using machine-learning software and manual review. Studies meeting the PECO criteria underwent quantitative data extraction and evaluation for risk of bias and sensitivity using the Integrated Risk Information System approach. Results: 193 epidemiology studies were identified, which included information on 15 of the PFAS of interest. The most commonly studied health effect categories were metabolic ( Discussion: Most of the PFAS in this SEM have little to no epidemiology data available to inform evaluation of potential health effects. Although exposure to the 15 PFAS that had data was fairly low in most studies, these less-studied PFAS may be used as replacements for "legacy" PFAS, leading to potentially greater exposure. It is impractical to generate epidemiology evidence to fill the existing gaps for all potentially relevant PFAS. This SEM highlights some of the important research gaps that currently exist. https://doi.org/10.1289/EHP11185.
MeSH term(s)	Female ; Fluorocarbons/chemistry ; Fluorocarbons/toxicity ; Humans ; Male ; Reproduction
Chemical Substances	Fluorocarbons
Language	English
Publishing date	2022-09-30
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	195189-0
ISSN	1552-9924 ; 0091-6765 ; 1078-0475
ISSN (online)	1552-9924
ISSN	0091-6765 ; 1078-0475
DOI	10.1289/EHP11185
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Article ; Online: Acute health effects associated with satellite-determined cyanobacterial blooms in a drinking water source in Massachusetts.

Wu, Jianyong / Hilborn, Elizabeth D / Schaeffer, Blake A / Urquhart, Erin / Coffer, Megan M / Lin, Cynthia J / Egorov, Andrey I

Environmental health : a global access science source

2021 Volume 20, Issue 1, Page(s) 83

Abstract: Background: The occurrence of cyanobacterial blooms in freshwater presents a threat to human health. However, epidemiological studies on the association between cyanobacterial blooms in drinking water sources and human health outcomes are scarce. The ... ...

Abstract	Background: The occurrence of cyanobacterial blooms in freshwater presents a threat to human health. However, epidemiological studies on the association between cyanobacterial blooms in drinking water sources and human health outcomes are scarce. The objective of this study was to evaluate if cyanobacterial blooms were associated with increased emergency room visits for gastrointestinal (GI), respiratory and dermal illnesses. Methods: Satellite-derived cyanobacteria cell concentrations were estimated in the source of drinking water for the Greater Boston area, during 2008-2011. Daily counts of hospital emergency room visits for GI, respiratory and dermal illnesses among drinking water recipients were obtained from an administrative record database. A two-stage model was used to analyze time-series data for an association between cyanobacterial blooms and the occurrence of illnesses. At the first stage, predictive autoregressive generalized additive models for Poisson-distributed outcomes were fitted to daily illness count data and daily predictive variables. At the second stage, residuals from the first stage models were regressed against lagged categorized cyanobacteria concentration estimates. Results: The highest cyanobacteria concentration (above the 75th percentile) was associated with an additional 4.3 cases of respiratory illness (95% confidence interval: 0.7, 8.0, p = 0.02, n = 268) compared to cyanobacteria concentrations below the 50th percentile in a two-day lag. There were no significant associations between satellite derived cyanobacterial concentrations and lagged data on GI or dermal illnesses. Conclusion: The study demonstrated a significant positive association between satellite-derived cyanobacteria concentrations in source water and respiratory illness occurring 2 days later. Future studies will require direct measures of cyanotoxins and health effects associated with exposure to cyanobacteria-impacted drinking water sources.
MeSH term(s)	Acute Disease ; Air Pollutants/analysis ; Cyanobacteria ; Drinking Water/microbiology ; Emergency Service, Hospital/statistics & numerical data ; Environmental Monitoring ; Eutrophication ; Gastrointestinal Diseases/epidemiology ; Humans ; Massachusetts/epidemiology ; Respiratory Tract Diseases/epidemiology ; Satellite Imagery ; Skin Diseases/epidemiology ; Water Pollutants
Chemical Substances	Air Pollutants ; Drinking Water ; Water Pollutants
Language	English
Publishing date	2021-07-16
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2092232-2
ISSN	1476-069X ; 1476-069X
ISSN (online)	1476-069X
ISSN	1476-069X
DOI	10.1186/s12940-021-00755-6
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Article ; Online: Flooding and Clostridium difficile Infection: A Case-Crossover Analysis.

Lin, Cynthia J / Wade, Timothy J / Hilborn, Elizabeth D

International journal of environmental research and public health

2015 Volume 12, Issue 6, Page(s) 6948–6964

Abstract: Clostridium difficile is a bacterium that can spread by water. It often causes acute gastrointestinal illness in older adults who are hospitalized and/or receiving antibiotics; however, community-associated infections affecting otherwise healthy ... ...

Abstract	Clostridium difficile is a bacterium that can spread by water. It often causes acute gastrointestinal illness in older adults who are hospitalized and/or receiving antibiotics; however, community-associated infections affecting otherwise healthy individuals have become more commonly reported. A case-crossover study was used to assess emergency room (ER) and outpatient visits for C. difficile infection following flood events in Massachusetts from 2003 through 2007. Exposure status was based on whether or not a flood occurred prior to the case/control date during the following risk periods: 0-6 days, 7-13 days, 14-20 days, and 21-27 days. Fixed-effects logistic regression was used to estimate the risk of diagnosis with C. difficile infection following a flood. There were 129 flood events and 1575 diagnoses of C. difficile infection. Among working age adults (19-64 years), ER and outpatient visits for C. difficile infection were elevated during the 7-13 days following a flood (Odds Ratio, OR = 1.69; 95% Confidence Interval, CI: 0.84, 3.37). This association was more substantial among males (OR = 3.21; 95% CI: 1.01-10.19). Associations during other risk periods were not observed (p < 0.05). Although we were unable to differentiate community-associated versus nosocomial infections, a potential increase in C. difficile infections should be considered as more flooding is projected due to climate change.
MeSH term(s)	Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Antibiotics, Antitubercular ; Climate Change ; Clostridium Infections/drug therapy ; Clostridium Infections/epidemiology ; Clostridium difficile/isolation & purification ; Cross-Over Studies ; Female ; Floods ; Humans ; Logistic Models ; Male ; Massachusetts/epidemiology ; Middle Aged ; Odds Ratio ; Sex Distribution ; Young Adult
Chemical Substances	Anti-Bacterial Agents ; Antibiotics, Antitubercular
Language	English
Publishing date	2015-06-17
Publishing country	Switzerland
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph120606948
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Article ; Online: Sanitary Sewer Overflows and Emergency Room Visits for Gastrointestinal Illness: Analysis of Massachusetts Data, 2006-2007.

Jagai, Jyotsna S / DeFlorio-Barker, Stephanie / Lin, Cynthia J / Hilborn, Elizabeth D / Wade, Timothy J

Environmental health perspectives

2017 Volume 125, Issue 11, Page(s) 117007

Abstract: Background: Sanitary sewer overflows (SSOs) occur when untreated sewage is discharged into water sources before reaching the treatment facility, potentially contaminating the water source with gastrointestinal pathogens.: Objectives: The objective of ...

Abstract	Background: Sanitary sewer overflows (SSOs) occur when untreated sewage is discharged into water sources before reaching the treatment facility, potentially contaminating the water source with gastrointestinal pathogens. Objectives: The objective of this paper is to assess associations between SSO events and rates of gastrointestinal (GI) illness in Massachusetts. Methods: A case-crossover study design was used to investigate association between SSO events and emergency room (ER) visits with a primary diagnosis of gastrointestinal (GI) illness in Massachusetts for 2006-2007. ER visits for GI were considered exposed if an SSO event occurred in the county of residence within three hazard periods, 0-4 d, 5-9 d, or 10-14 d, before the visit. A time-stratified bidirectional design was used to select control days for each ER visit on the same day of the week during the same month. Fixed effect logistic regression models were used to estimate the risk of ER visits following the SSO event. Results: During the study period, there were 270 SSO events for northeastern Massachusetts and 66,460 ER admissions with GI illness listed as the primary diagnostic code. The overall odds ratio (OR) for ER visits for GI illness was 1.09 [95% confidence interval (CI): 1.03, 1.16] in the 10-14 d period following an SSO event, with positive ORs for all age groups and for three of the four counties. The 0-4 d and 5-9 d periods following an SSO event were not associated with ER visits for GI illness overall, and associations by county or age were inconsistent. Conclusions: We demonstrated an association between SSO events and ER visits for GI illness using a case-crossover study design. In light of the aging water infrastructure in the United States and the expected increase in heavy rainfall events, our findings suggest a potential health impact associated with sewage overflows. https://doi.org/10.1289/EHP2048.
MeSH term(s)	Drainage, Sanitary/statistics & numerical data ; Emergency Service, Hospital ; Gastrointestinal Diseases/epidemiology ; Hospitalization/statistics & numerical data ; Humans ; Logistic Models ; Massachusetts/epidemiology ; Sewage ; Waste Disposal, Fluid
Chemical Substances	Sewage
Language	English
Publishing date	2017-11-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	195189-0
ISSN	1552-9924 ; 0091-6765 ; 1078-0475
ISSN (online)	1552-9924
ISSN	0091-6765 ; 1078-0475
DOI	10.1289/EHP2048
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Article ; Online: Emergency Department Visits for Acute Gastrointestinal Illness After a Major Water Pipe Break in 2010.

Lin, Cynthia J / Richardson, David B / Hilborn, Elizabeth D / Weinberg, Howard / Engel, Larry S / Wade, Timothy J

Epidemiology (Cambridge, Mass.)

2019 Volume 30, Issue 6, Page(s) 893–900

Abstract: Background: When a water pipe breaks, contaminants can enter the drinking water system and cause waterborne illnesses such as acute gastrointestinal illness. In May 2010, a major water pipe broke near Boston, MA, and a boil water order was issued to ... ...

Abstract	Background: When a water pipe breaks, contaminants can enter the drinking water system and cause waterborne illnesses such as acute gastrointestinal illness. In May 2010, a major water pipe broke near Boston, MA, and a boil water order was issued to nearly two million residents. Methods: Using a case-crossover study design, we examined the association between the water pipe break and subsequent emergency department visits for acute gastrointestinal illness. We identified cases of illness according to ICD-9-CM diagnosis codes and selected control dates 2 weeks before and after each case. We estimated the risk of visiting the emergency department during the 0-3 and 4-7 days after the water pipe break using conditional logistic regression models. Results: Our analysis included 5,726 emergency department visits for acute gastrointestinal illness from 3 April 2010 to 5 June 2010. Overall, there was a 1.3-fold increased odds for visiting the emergency department for acute gastrointestinal illness during the 0-3 days after the water pipe break (odds ratio [OR] = 1.3; 95% confidence interval [CI] = 1.1, 1.4) compared with referent dates selected 2 weeks before and after. During the 4-7 days after the break, the association diminished overall (OR = 1.1; 95% CI = 0.96, 1.2). However, in communities over 12 miles from the break, the 4- to 7-day association was elevated (OR = 1.4; 95% CI = 1.1, 1.8). Conclusions: This study suggests that a major water pipe break was associated with emergency department visits for acute gastrointestinal illness, particularly during the 0-3 days after the break, when a boil water order was in effect.
MeSH term(s)	Acute Disease ; Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Colitis/epidemiology ; Diarrhea/epidemiology ; Drinking Water ; Emergency Service, Hospital/statistics & numerical data ; Female ; Gastroenteritis/epidemiology ; Gastrointestinal Diseases/epidemiology ; Humans ; Infant ; Male ; Massachusetts/epidemiology ; Middle Aged ; Nausea/epidemiology ; Odds Ratio ; Vomiting/epidemiology ; Water Supply/statistics & numerical data ; Young Adult
Chemical Substances	Drinking Water
Language	English
Publishing date	2019-08-19
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1053263-8
ISSN	1531-5487 ; 1044-3983
ISSN (online)	1531-5487
ISSN	1044-3983
DOI	10.1097/EDE.0000000000001083
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Article ; Online: Erratum: "Sanitary Sewer Overflows and Emergency Room Visits for Gastrointestinal Illness: Analysis of Massachusetts Data, 2006-2007".

Jagai, Jyotsna S / DeFlorio-Barker, Stephanie / Lin, Cynthia J / Hilborn, Elizabeth D / Wade, Timothy J

Environmental health perspectives

2017 Volume 125, Issue 12, Page(s) 129003

Abstract: This corrects the article DOI: 10.1289/EHP2048.]. ...

Abstract	[This corrects the article DOI: 10.1289/EHP2048.].
Language	English
Publishing date	2017-12-19
Publishing country	United States
Document type	Journal Article ; Published Erratum
ZDB-ID	195189-0
ISSN	1552-9924 ; 0091-6765 ; 1078-0475
ISSN (online)	1552-9924
ISSN	0091-6765 ; 1078-0475
DOI	10.1289/EHP3143
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Article ; Online: Flooding and emergency room visits for gastrointestinal illness in Massachusetts: a case-crossover study.

Wade, Timothy J / Lin, Cynthia J / Jagai, Jyotsna S / Hilborn, Elizabeth D

PloS one

2014 Volume 9, Issue 10, Page(s) e110474

Abstract: Introduction: Floods and other severe weather events are anticipated to increase as a result of global climate change. Floods can lead to outbreaks of gastroenteritis and other infectious diseases due to disruption of sewage and water infrastructure and ...

Abstract	Introduction: Floods and other severe weather events are anticipated to increase as a result of global climate change. Floods can lead to outbreaks of gastroenteritis and other infectious diseases due to disruption of sewage and water infrastructure and impacts on sanitation and hygiene. Floods have also been indirectly associated with outbreaks through population displacement and crowding. Methods: We conducted a case-crossover study to investigate the association between flooding and emergency room visits for gastrointestinal illness (ER-GI) in Massachusetts for the years 2003 through 2007. We obtained ER-GI visits from the State of Massachusetts and records of floods from the National Oceanic and Atmospheric Association's Storm Events Database. ER-GI visits were considered exposed if a flood occurred in the town of residence within three hazard periods of the visit: 0-4 days; 5-9 days; and 10-14 days. A time-stratified bi-directional design was used for control selection, matching on day of the week with two weeks lead or lag time from the ER-GI visit. Fixed effect logistic regression models were used to estimate the risk of ER-GI visits following the flood. Results and conclusions: A total of 270,457 ER-GI visits and 129 floods occurred in Massachusetts over the study period. Across all counties, flooding was associated with an increased risk for ER-GI in the 0-4 day period after flooding (Odds Ratio: 1.08; 95% Confidence Interval: 1.03-1.12); but not the 5-9 days (Odds Ratio: 0.995; 95% Confidence Interval: 0.955-1.04) or the 10-14 days after (Odds Ratio: 0.966, 95% Confidence Interval: 0.927-1.01). Similar results were observed for different definitions of ER-GI. The effect differed across counties, suggesting local differences in the risk and impact of flooding. Statewide, across the study period, an estimated 7% of ER-GI visits in the 0-4 days after a flood event were attributable to flooding.
MeSH term(s)	Cross-Over Studies ; Emergency Treatment/statistics & numerical data ; Floods/history ; Floods/statistics & numerical data ; Gastrointestinal Diseases/epidemiology ; Gastrointestinal Diseases/etiology ; History, 21st Century ; Humans ; Logistic Models ; Massachusetts/epidemiology ; Odds Ratio
Language	English
Publishing date	2014-10-17
Publishing country	United States
Document type	Historical Article ; Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0110474
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Extreme precipitation and emergency room visits for influenza in Massachusetts: a case-crossover analysis.

Smith, Genee S / Messier, Kyle P / Crooks, James L / Wade, Timothy J / Lin, Cynthia J / Hilborn, Elizabeth D

Environmental health : a global access science source

2017 Volume 16, Issue 1, Page(s) 108

Abstract: Background: Influenza peaks during the wintertime in temperate regions and during the annual rainy season in tropical regions - however reasons for the observed differences in disease ecology are poorly understood. We hypothesize that episodes of ... ...

Abstract	Background: Influenza peaks during the wintertime in temperate regions and during the annual rainy season in tropical regions - however reasons for the observed differences in disease ecology are poorly understood. We hypothesize that episodes of extreme precipitation also result in increased influenza in the Northeastern United States, but this association is not readily apparent, as no defined 'rainy season' occurs. Our objective was to evaluate the association between extreme precipitation (≥ 99th percentile) events and risk of emergency room (ER) visit for influenza in Massachusetts during 2002-2008. Methods: A case-crossover analysis of extreme precipitation events and influenza ER visits was conducted using hospital administrative data including patient town of residence, date of visit, age, sex, and associated diagnostic codes. Daily precipitation estimates were generated for each town based upon data from the National Oceanic and Atmospheric Administration. Odds ratio (OR) and 95% confidence intervals (CI) for associations between extreme precipitation and ER visits for influenza were estimated using conditional logistic regression. Results: Extreme precipitation events were associated with an OR = 1.23 (95%CI: 1.16, 1.30) for ER visits for influenza at lag days 0-6. There was significant effect modification by race, with the strongest association observed among Blacks (OR = 1.48 (1.30, 1.68)). Conclusions: We observed a positive association between extreme precipitation events and ER visits for influenza, particularly among Blacks. Our results suggest that influenza is associated with extreme precipitation in a temperate area; this association could be a result of disease ecology, behavioral changes such as indoor crowding, or both. Extreme precipitation events are expected to increase in the Northeastern United States as climate change progresses. Additional research exploring the basis of this association can inform potential interventions for extreme weather events and influenza transmission.
Language	English
Publishing date	2017-10-17
Publishing country	England
Document type	Journal Article
ISSN	1476-069X
ISSN (online)	1476-069X
DOI	10.1186/s12940-017-0312-7
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Article ; Online: A Prospective Study of Marine Phytoplankton and Reported Illness Among Recreational Beachgoers in Puerto Rico, 2009.

Lin, Cynthia J / Wade, Timothy J / Sams, Elizabeth A / Dufour, Alfred P / Chapman, Andrew D / Hilborn, Elizabeth D

Environmental health perspectives

2016 Volume 124, Issue 4, Page(s) 477–483

Abstract: Background: Blooms of marine phytoplankton may adversely affect human health. The potential public health impact of low-level exposures is not well established, and few prospective cohort studies of recreational exposures to marine phytoplankton have ... ...

Abstract	Background: Blooms of marine phytoplankton may adversely affect human health. The potential public health impact of low-level exposures is not well established, and few prospective cohort studies of recreational exposures to marine phytoplankton have been conducted. Objective: We evaluated the association between phytoplankton cell counts and subsequent illness among recreational beachgoers. Methods: We recruited beachgoers at Boquerón Beach, Puerto Rico, during the summer of 2009. We conducted interviews at three time points to assess baseline health, water activities, and subsequent illness. Daily water samples were quantitatively assayed for phytoplankton cell count. Logistic regression models, adjusted for age and sex, were used to assess the association between exposure to three categories of phytoplankton concentration and subsequent illness. Results: During 26 study days, 15,726 individuals successfully completed all three interviews. Daily total phytoplankton cell counts ranged from 346 to 2,012 cells/mL (median, 712 cells/mL). The category with the highest (≥ 75th percentile) total phytoplankton cell count was associated with eye irritation [adjusted odds ratio (OR) = 1.30; 95% confidence interval (CI): 1.01, 1.66], rash (OR = 1.27; 95% CI: 1.02, 1.57), and earache (OR = 1.25; 95% CI: 0.88, 1.77). In phytoplankton group-specific analyses, the category with the highest Cyanobacteria counts was associated with respiratory illness (OR = 1.37; 95% CI: 1.12, 1.67), rash (OR = 1.32; 95% CI: 1.05, 1.66), eye irritation (OR = 1.25; 95% CI: 0.97, 1.62), and earache (OR = 1.35; 95% CI: 0.95, 1.93). Conclusions: We found associations between recreational exposure to marine phytoplankton and reports of eye irritation, respiratory illness, and rash. We also found that associations varied by phytoplankton group, with Cyanobacteria having the strongest and most consistent associations. Citation: Lin CJ, Wade TJ, Sams EA, Dufour AP, Chapman AD, Hilborn ED. 2016. A prospective study of marine phytoplankton and reported illness among recreational beachgoers in Puerto Rico, 2009. Environ Health Perspect 124:477-483; http://dx.doi.org/10.1289/ehp.1409558.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bathing Beaches/statistics & numerical data ; Child ; Child, Preschool ; Cohort Studies ; Cyanobacteria/isolation & purification ; Environmental Exposure/statistics & numerical data ; Exanthema/microbiology ; Eye Diseases/microbiology ; Female ; Humans ; Infant ; Male ; Middle Aged ; Phytoplankton/isolation & purification ; Prospective Studies ; Puerto Rico ; Recreation ; Respiratory Tract Diseases/microbiology ; Seawater/adverse effects ; Seawater/microbiology
Language	English
Publishing date	2016-04
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	195189-0
ISSN	1552-9924 ; 0091-6765 ; 1078-0475
ISSN (online)	1552-9924
ISSN	0091-6765 ; 1078-0475
DOI	10.1289/ehp.1409558
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Article ; Online: Accuracy and reliability of self-reported weight and height in the Sister Study.

Lin, Cynthia J / DeRoo, Lisa A / Jacobs, Sara R / Sandler, Dale P

Public health nutrition

2011 Volume 15, Issue 6, Page(s) 989–999

Abstract: Objective: To assess the accuracy and reliability of self-reported weight and height and identify the factors associated with reporting accuracy.: Design: Analysis of self-reported and measured weight and height from participants in the Sister Study ( ...

Abstract	Objective: To assess the accuracy and reliability of self-reported weight and height and identify the factors associated with reporting accuracy. Design: Analysis of self-reported and measured weight and height from participants in the Sister Study (2003-2009), a nationwide cohort of 50 884 women aged 35-74 years in the USA with a sister with breast cancer. Setting: Weight and height were reported via computer-assisted telephone interview (CATI) and self-administered questionnaires, and measured by examiners. Subjects: Early enrolees in the Sister Study. There were 18 639 women available for the accuracy analyses and 13 316 for the reliability analyses. Results: Using weighted kappa statistics, comparisons were made between CATI responses and examiner measures to assess accuracy and CATI and questionnaire responses to assess reliability. Polytomous logistic regression evaluated factors associated with over- or under-reporting. Compared with measured values, agreement was 96 % for reported height (±1 inch (±2·5 cm); weighted κ = 0·84) and 67 % for weight (±3 lb (±1·36 kg); weighted κ = 0·92). Obese women (BMI ≥ 30 kg/m2) were more likely than normal-weight women to under-report weight by ≥5 % and underweight women (BMI < 18·5 kg/m2) were more likely to over-report. Among normal-weight and overweight women (18·5 kg/m2 ≤ BMI < 30 kg/m2), weight cycling and lifetime weight difference ≥50 lb (≥22·68 kg) were associated with over-reporting. Conclusions: US women in the Sister Study were reasonably reliable and accurate in reporting weight and height. Women with normal-range BMI reported most accurately. Overweight and obese women and those with weight fluctuations were less accurate, but even among obese women, few under-reported their weight by >10 %.
MeSH term(s)	Adult ; Aged ; Body Height ; Body Mass Index ; Body Weight ; Cohort Studies ; Female ; Health Surveys/methods ; Humans ; Interviews as Topic ; Logistic Models ; Middle Aged ; Obesity ; Reference Values ; Reproducibility of Results ; Self Report ; Siblings ; Surveys and Questionnaires ; Thinness ; United States
Language	English
Publishing date	2011-12-09
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Intramural ; Validation Study
ZDB-ID	1436024-x
ISSN	1475-2727 ; 1368-9800
ISSN (online)	1475-2727
ISSN	1368-9800
DOI	10.1017/S1368980011003193
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