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Article ; Online: Modified pedicle screw fixation under guidance of stress analysis for cervicothoracic junction: Surgical technique and outcomes.

Jiang, Chuanjie / Yang, Yongjun / Yu, Jianlin / Zhou, Jiping / Lin, Haipeng / Duan, Xiuyang / Li, Jinjian

Journal of back and musculoskeletal rehabilitation

2023 Volume 36, Issue 5, Page(s) 1087–1094

Abstract: Background: In cervicothoracic junction, the use of strong fixation device such as pedicle screw placement is often needed.: Objective: The current study aimed to evaluate the accuracy and safety of pedicle screw placement using stress conduction ... ...

Abstract	Background: In cervicothoracic junction, the use of strong fixation device such as pedicle screw placement is often needed. Objective: The current study aimed to evaluate the accuracy and safety of pedicle screw placement using stress conduction analysis in the clinical application. Methods: We retrospectively collected patients who underwent pedicle screw internal fixation in cervicothoracic junction. Patients were divided into conventional nail placement (Group A) and modified pedicle screw implantation under guidance of stress analysis (Group B) according to the methods of pedicle screw placement. The accuracy of pedicle screw placement was assessed by computed tomography (CT) examination, and the success rate was calculated. Results: A total of 80 patients who underwent pedicle screw internal fixation in cervicothoracic junction were included. There were no obvious differences in baseline characteristics between two groups. The success rate of total screw placement, cervical spine screw placement and upper thoracic spine screw placement in Group B was higher than those in Group A (P< 0.001, P= 0.005, P= 0.008). Additionally, Heary Grade I in the Group B was higher than Group A (P= 0.001). Conclusion: Stress analysis-guided technique can increase the accuracy of pedicle screw placement. Importantly, it meets the requirements of internal fixation of the cervicothoracic junction.
MeSH term(s)	Humans ; Pedicle Screws ; Retrospective Studies ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Tomography, X-Ray Computed ; Spinal Fusion/methods
Language	English
Publishing date	2023-05-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1184721-9
ISSN	1878-6324 ; 1053-8127
ISSN (online)	1878-6324
ISSN	1053-8127
DOI	10.3233/BMR-220154
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Investigation of Exfoliation Efficiency of 6H-SiC Implanted Sequentially with He

You, Guoqiang / Lin, Haipeng / Qu, Yanfeng / Hao, Jie / You, Suyuan / Li, Bingsheng

Materials (Basel, Switzerland)

2022 Volume 15, Issue 8

Abstract: Silicon carbide (SiC) is a promising material used in the advanced semiconductor industry. Fabricating SiC-on-insulator via H implantation is a good method. He and H co-implantation into Si can efficiently enhance exfoliation efficiency compared to only ... ...

Abstract	Silicon carbide (SiC) is a promising material used in the advanced semiconductor industry. Fabricating SiC-on-insulator via H implantation is a good method. He and H co-implantation into Si can efficiently enhance exfoliation efficiency compared to only H implantation. In this study, 6H-SiC single crystals were implanted with He
Language	English
Publishing date	2022-04-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma15082941
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Temperature-Dependent Evaporative Anthropogenic VOC Emissions Significantly Exacerbate Regional Ozone Pollution.

Environmental science & technology

2024 Volume 58, Issue 12, Page(s) 5430–5441

Abstract: The evaporative emissions of anthropogenic volatile organic compounds (AVOCs) are sensitive to ambient temperature. This sensitivity forms an air pollution-meteorology connection that has not been assessed on a regional scale. We parametrized the ... ...

Abstract	The evaporative emissions of anthropogenic volatile organic compounds (AVOCs) are sensitive to ambient temperature. This sensitivity forms an air pollution-meteorology connection that has not been assessed on a regional scale. We parametrized the temperature dependence of evaporative AVOC fluxes in a regional air quality model and evaluated the impacts on surface ozone in the Beijing-Tianjin-Hebei (BTH) area of China during the summer of 2017. The temperature dependency of AVOC emissions drove an enhanced simulated ozone-temperature sensitivity of 1.0 to 1.8 μg m
MeSH term(s)	Ozone/analysis ; Air Pollutants/analysis ; Volatile Organic Compounds/analysis ; Temperature ; Environmental Monitoring/methods ; Air Pollution ; China
Chemical Substances	Ozone (66H7ZZK23N) ; Air Pollutants ; Volatile Organic Compounds
Language	English
Publishing date	2024-03-12
Publishing country	United States
Document type	Journal Article
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.3c09122
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Impacts of Ship Emissions on Air Quality in Southern China: Opportunistic Insights from the Abrupt Emission Changes in Early 2020.

Feng, Xu / Ma, Yaping / Lin, Haipeng / Fu, Tzung-May / Zhang, Yan / Wang, Xiaolin / Zhang, Aoxing / Yuan, Yupeng / Han, Zimin / Mao, Jingbo / Wang, Dakang / Zhu, Lei / Wu, Yujie / Li, Ying / Yang, Xin

Environmental science & technology

2023 Volume 57, Issue 44, Page(s) 16999–17010

Abstract: In early 2020, two unique events perturbed ship emissions of pollutants around Southern China, proffering insights into the impacts of ship emissions on regional air quality: the decline of ship activities due to COVID-19 and the global enforcement of ... ...

Abstract	In early 2020, two unique events perturbed ship emissions of pollutants around Southern China, proffering insights into the impacts of ship emissions on regional air quality: the decline of ship activities due to COVID-19 and the global enforcement of low-sulfur (<0.5%) fuel oil for ships. In January and February 2020, estimated ship emissions of NO
MeSH term(s)	Air Pollutants/analysis ; Ships ; Vehicle Emissions/analysis ; Particulate Matter/analysis ; Fuel Oils ; Nitrogen Dioxide ; Air Pollution/analysis ; China ; Ozone/analysis ; Sulfur ; Environmental Monitoring/methods
Chemical Substances	Air Pollutants ; Vehicle Emissions ; Particulate Matter ; Fuel Oils ; Nitrogen Dioxide (S7G510RUBH) ; Ozone (66H7ZZK23N) ; Sulfur (70FD1KFU70)
Language	English
Publishing date	2023-10-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.3c04155
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Modeling the high-mercury wet deposition in the southeastern US with WRF-GC-Hg v1.0

Xu, Xiaotian / Feng, Xu / Lin, Haipeng / Zhang, Peng / Huang, Shaojian / Song, Zhengcheng / Peng, Yiming / Fu, Tzung-May / Zhang, Yanxu

eISSN: 1991-9603

2022

Abstract: High-mercury wet deposition in the southeastern United States has been noticed for many years. Previous studies came up with a theory that it was associated with high-altitude divalent mercury scavenged by convective precipitation. Given the coarse ... ...

Abstract	High-mercury wet deposition in the southeastern United States has been noticed for many years. Previous studies came up with a theory that it was associated with high-altitude divalent mercury scavenged by convective precipitation. Given the coarse resolution of previous models (e.g., GEOS-Chem), this theory is still not fully tested. Here we employed a newly developed WRF-GEOS-Chem (WRF-GC; WRF: Weather Research Forecasting) model implemented with mercury simulation (WRF-GC-Hg v1.0). We conduct extensive model benchmarking by comparing WRF-GC with different resolutions (from 50 to 25 km) to GEOS-Chem output (4 ∘ × 5 ∘ ) and data from the Mercury Deposition Network (MDN) in July–September 2013. The comparison of mercury wet deposition from two models presents high-mercury wet deposition in the southeastern United States. We divided simulation results by heights (2, 4, 6, 8 km), different types of precipitation (large-scale and convective), and combinations of these two variations together and find most mercury wet deposition concentrates on higher level and is caused by convective precipitation. Therefore, we conclude that it is the deep convection that caused enhanced mercury wet deposition in the southeastern United States.
Subject code	333
Language	English
Publishing date	2022-05-12
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: MicroRNA profiling in BEAS-2B cells exposed to alpha radiation reveals potential biomarkers for malignant cellular transformation.

Dang, Xuhong / Lin, Haipeng / Li, Youchen / Guo, Xiuli / Yuan, Yayi / Zhang, Ruifeng / Li, Xiaozhen / Chai, Dongliang / Zuo, Yahui

Toxicology research

2020 Volume 9, Issue 6, Page(s) 834–844

Abstract: The carcinogenicity of radon has been convincingly documented through epidemiological studies of underground miners. The risk of lung cancer from radon exposure is due to the continuous radioactive decay of this gas and subsequent emission of high-energy ...

Abstract	The carcinogenicity of radon has been convincingly documented through epidemiological studies of underground miners. The risk of lung cancer from radon exposure is due to the continuous radioactive decay of this gas and subsequent emission of high-energy alpha decay particles. And the bronchial epithelial cells are the main targets of radon exposure. However, there is a lack of early warning indicators of lung cancer caused by radon in the physical examination of populations involved in occupations with higher exposure to radon. To assess the potential of a molecular-based marker approach for the early detection of human lung cancer induced by radon, human bronchial epithelial cell injury models induced by alpha-particle irradiation were constructed. The results of transwell migration assay, transwell invasion assay, and the expression of the epithelial-mesenchymal transition-related proteins showed that malignant cell transformation could be triggered by alpha irradiation. Potential microRNAs (miRNAs) (hsa-miR-3907, hsa-miR-6732-3p, hsa-miR-4788, hsa-miR-5001-5p, and hsa-miR-4257) were screened using miRNA chips in cell models. The pathway analyses of miRNAs selected using DIANA-miRPath v3.0 showed that miRNAs involved in malignant cell transformation were associated with cell adhesion molecules, extracellular matrix receptor interaction, and proteoglycans in cancer, among others, which are closely related to the occurrence and development of carcinogenesis. Reverse Transcription Quantitative Real-Time PCR (RT-qPCR) assay showed that five screened miRNAs were up-regulated in five lung cancer tissue samples. In conclusion, the results indicated that hsa-miR-3907, hsa-miR-6732-3p, hsa-miR-4788, hsa-miR-5001-5p, and hsa-miR-4257 may be potential early markers of the malignant transformation of bronchial epithelial cells induced by alpha-particle irradiation.
Language	English
Publishing date	2020-12-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2684701-2
ISSN	2045-4538 ; 2045-452X
ISSN (online)	2045-4538
ISSN	2045-452X
DOI	10.1093/toxres/tfaa094
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: NOx emission reduction and recovery during COVID-19 in East China

Zhang, Ruixiong / Zhang, Yuzhong / Lin, Haipeng / Feng, Xu / Fu, Tzung-May / Wang, Yuhang

Atmosphere

Abstract: Since its first confirmed case at the end of 2019, COVID-19 has become a global pandemic in three months with more than 1.4 million confirmed cases worldwide, as of early April 2020. Quantifying the changes of pollutant emissions due to COVID-19 and ... ...

Abstract	Since its first confirmed case at the end of 2019, COVID-19 has become a global pandemic in three months with more than 1.4 million confirmed cases worldwide, as of early April 2020. Quantifying the changes of pollutant emissions due to COVID-19 and associated governmental control measures is crucial to understand its impacts on economy, air pollution, and society. We used the WRF-GC model and the tropospheric NO2 column observations retrieved by the TROPOMI instrument to derive the top-down NOx emission change estimation between the three periods: P1 (January 1st to January 22nd, 2020), P2 (January 23rd, Wuhan lockdown, to February 9th, 2020), and P3 (February 10th, back-to-work day, to March 12th, 2020). We found that NOx emissions in East China averaged during P2 decreased by 50% compared to those averaged during P1. The NOx emissions averaged during P3 increased by 26% compared to those during P2. Most provinces in East China gradually regained some of their NOx emissions after February 10, the official back-to-work day, but NOx emissions in most provinces have not yet to return to their previous levels in early January. NOx emissions in Wuhan, the first epicenter of COVID-19, had no sign of emission recovering by March 12. A few provinces, such as Zhejiang and Shanxi, have recovered fast, with their averaged NOx emissions during P3 almost back to pre-lockdown levels.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #635556
Database	COVID19

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Article ; Online: Top-down NOx emission changes in China using TROPOMI NO2 data from Jan 1 to Mar 12, 2020

Zhang, Ruixiong / Zhang, Yuzhong / Lin, Haipeng / Feng, Xu / Fu, Tzung-May / Wang, Yuhang

2020

Abstract: This datasets contains the top-down NOx emission data during Jan 1 - Mar 12, 2020, derived in the paper NOx emission reduction and recovery during COVID-19 in East China (https://www.mdpi.com/2073-4433/11/4/433). The top-down NOx emission changes can be ... ...

Abstract	This datasets contains the top-down NOx emission data during Jan 1 - Mar 12, 2020, derived in the paper NOx emission reduction and recovery during COVID-19 in East China (https://www.mdpi.com/2073-4433/11/4/433). The top-down NOx emission changes can be used as a measure to assess the socioeconomic activity changes due to COVID-19 control measures. Data Description: regional_emission_changes_TableS1.xlsx: The derived NOx emission changes in China at regional (East China), provincial, and city (Wuhan) levels. regional_emission_timeseries.zip: The timeseries plots of NOx emission changes in the mentioned regions NO2_VCD_NOx_emission.nc: This contains data used to derive the top-down NOx emissions (at 0.05 degree resolution): NO2 data from TROPOMI and WRF-GC; NOx emissions from MEIC emission inventory. How to Cite: Please cite both the Zenodo dataset and the paper (https://www.mdpi.com/2073-4433/11/4/433, Zhang, R.; Zhang, Y.; Lin, H.; Feng, X.; Fu, T.-M.; Wang, Y. NOx Emission Reduction and Recovery during COVID-19 in East China. Atmosphere 2020, 11, 433.). Contact: If you have questions, please contact the corresponding authors Drs. Ruixiong Zhang (zhangruixiong@gmail.com) and Yuzhong Zhang (zhangyuzhong@westlake.edu.cn). Paper Abstract: Since its first confirmed case at the end of 2019, COVID-19 has become a global pandemic in three months with more than 1.4 million confirmed cases worldwide, as of early April 2020. Quantifying the changes of pollutant emissions due to COVID-19 and associated governmental control measures is crucial to understand its impacts on economy, air pollution, and society. We used the WRF-GC model and the tropospheric NO2 column observations retrieved by the TROPOMI instrument to derive the top-down NOx emission change estimation between the three periods: P1 (January 1st – January 22nd, 2020), P2 (January 23rd, Wuhan lockdown – February 9th, 2020), and P3 (February 10th, back-to-work day – March 12th, 2020). We found that NOx emissions in East China averaged during P2 decreased by 50% compared to those averaged during P1. The NOx emissions averaged during P3 increased by 26% compared to those during P2. Most provinces in East China gradually regained some of their NOx emissions after February 10, the official back-to-work day, but NOx emissions in most provinces has not yet to return to their previous levels in early January. NOx emissions in Wuhan, the first epicenter of COVID-19, had no sign of emission recovering by March 12. A few provinces, such as Zhejiang and Shanxi, have recovered fast, with their averaged NOx emissions during P3 almost back to pre-lockdown levels.
Keywords	NOx emission ; TROPOMI ; China ; COVID-19 ; Environment ; Air quality ; covid19
Subject code	950
Publishing date	2020-04-22
Publishing country	eu
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Ryanodine receptor antagonism alleviates skeletal muscle ischemia reperfusion injury by modulating TNF-α and IL-10.

Lin, Hai-Peng / Zheng, Yan-Qing / Zhou, Zhi-Ping / Wang, Gao-Xiong / Guo, Ping-Fan

Clinical hemorheology and microcirculation

2018 Volume 70, Issue 1, Page(s) 51–58

Abstract: Background: Intracellular calcium overload has been implicated in various pathological conditions including ischemia reperfusion injury. This study aims to explore the effect and probable mechanism of dantrolene, a ryanodine receptor and intracellular ... ...

Abstract	Background: Intracellular calcium overload has been implicated in various pathological conditions including ischemia reperfusion injury. This study aims to explore the effect and probable mechanism of dantrolene, a ryanodine receptor and intracellular calcium antagonist, on the skeletal muscle ischemia reperfusion injury. Materials and methods: SD rats were randomly divided into three groups: sham group which underwent anaesthesia and exposure of femoral vein, reperfusion group that received 2 h ischemia and the amount of diluent via femoral vein before 4 h reperfusion, dantrolene group that underwent 2 h ischemia and was given 2 mg/kg dantrolene via femoral vein before 4 h reperfusion. The parameters measured at the end of reperfusion included serum maleic dialdehyde (MDA), tissue myeloperoxidase (MPO) and muscle histology, as well as serum TNF-α and IL-10. Results: Levels of MDA, MPO and TNF-α increased in the reperfusion group, whereas the relevant expressions in the dantrolene group decreased significantly. Histological examination demonstrated significant improvements between the same both groups. IL-10 reflected the protection observed above with a significant up-regulation of expression after dantrolene administration. Conclusion: Ryanodine receptor antagonist dantrolene exerted a significant protective effect against the inflammatory injury of skeletal muscle ischemia reperfusion. The underlying molecular mechanism is probably related to the suppression of TNF-α levels and the increment of IL-10 expression.
MeSH term(s)	Animals ; Humans ; Interleukin-10/metabolism ; Male ; Muscle, Skeletal/metabolism ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Ryanodine Receptor Calcium Release Channel/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	Ryanodine Receptor Calcium Release Channel ; Tumor Necrosis Factor-alpha ; Interleukin-10 (130068-27-8)
Language	English
Publishing date	2018-04-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1381750-4
ISSN	1875-8622 ; 1386-0291
ISSN (online)	1875-8622
ISSN	1386-0291
DOI	10.3233/CH-170276
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Quantitative Proteomics Analysis of Differentially Expressed Proteins in Serum of Former Uranium Miners by Isobaric Tags for the Relative and Absolute Quantitation.

Dang, Xuhong / Lin, Haipeng / Yuan, Yayi / Yang, Biao / Dong, Juancong / Zhang, Zhongxin / Yang, Kai / Li, Youchen / Li, Xiaozhen / Chai, Dongliang / Zuo, Yahui

Dose-response : a publication of International Hormesis Society

2021 Volume 19, Issue 4, Page(s) 15593258211056190

Abstract: The carcinogenicity of radon has been convincingly documented through epidemiological studies of underground miners. However, there is a lack of early warning indicators for radon radiation damage. In this study, mixed serum samples of 3 groups were ... ...

Abstract	The carcinogenicity of radon has been convincingly documented through epidemiological studies of underground miners. However, there is a lack of early warning indicators for radon radiation damage. In this study, mixed serum samples of 3 groups were collected from 27 underground uranium miners and seven aboveground miners according to the radiation exposure dose. The differentially expressed proteins in the serum were identified using the isobaric tags for the relative and absolute quantitation (iTRAQ)-based method. Some differentially expressed proteins were validated by enzyme-linked immunosorbent assay (ELISA) in 84 underground and 32 aboveground miners. A total of 25 co-differentially expressed proteins in 2 underground miner groups were screened, of which 9 were downregulated and 13 were upregulated. Biological process analysis of these proteins using Metascape showed that 5 GO terms were enriched, such as negative regulation of very-low-density lipoprotein particle clearance, endocytosis, and regulated exocytosis. The results of the ELISA for the expression levels of GCN1, CIP2A, and IGHV1-24 in the serum of 116 miners' serum showed that the levels of GCN1 and CIP2A were consistent with the iTRAQ results. In conclusion, APOC1, APOC2, APOC3, ORM1, ORM2, ANTXR1, GCN1, and CIP2A may be potential early markers of radon radiation damage.
Language	English
Publishing date	2021-11-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2440820-7
ISSN	1559-3258 ; 1559-3258
ISSN (online)	1559-3258
ISSN	1559-3258
DOI	10.1177/15593258211056190
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