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  1. Book ; Conference proceedings: Special issue hydropedology: Fundamental issues and practical applications

    Lin, Henry

    [selected papers from the Hydropedology Symposium held at the 18th World Congress of Soil Science in July 9 - 15, 2006 in Philadelphia, PA, USA]

    (Catena ; 73,2)

    2008  

    Title variant Hydropedology: Fundamental issues and practical applications
    Event/congress Hydropedology Symposium (2006, PhiladelphiaPa.) ; World Congress of Soil Science (18, 2006, PhiladelphiaPa.)
    Author's details ed. by: H. Lin
    Series title Catena ; 73,2
    Collection
    Keywords Boden ; Hydrologie
    Subject Gewässerkunde ; Hydrographie ; Hydrografie ; Gewässerforschung ; Wasserforschung ; Böden ; Erdboden ; Erde ; Erdreich
    Language English
    Size S. [151] - 224 : Ill., graph. Darst., Kt.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT015518528
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Book ; Conference proceedings: Special issue Hydropedology

    Lin, Henry

    bridging disciplines, scales and data ; [was held during the annual meeting of the Soil Science Society of America (SSSA) in Nov. 3 - 5, 2003 Denver Colorado]

    (Geoderma ; 131,3/4)

    2005  

    Title variant Hydropedology
    Event/congress Symposium on Hydropedology: Bridging Disciplines, Scales, and Data (2003, DenverColo.)
    Author's details [Symposium on Hydropedology: Bridging Disciplines, Scales, and Data]. Ed. by H. Lin
    Series title Geoderma ; 131,3/4
    Collection
    Language English
    Size 108 S. : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT014694851
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Article ; Online: Alagille syndrome: understanding the genotype-phenotype relationship and its potential therapeutic impact.

    Halma, Jennifer / Lin, Henry C

    Expert review of gastroenterology & hepatology

    2023  Volume 17, Issue 9, Page(s) 883–892

    Abstract: Introduction: Alagille syndrome (ALGS) is an autosomal dominant, multisystem genetic disorder with wide phenotypic variability caused by mutations in the Notch signaling pathway, specifically from mutations in either the Jagged1 (JAG1) or NOTCH2 gene. ... ...

    Abstract Introduction: Alagille syndrome (ALGS) is an autosomal dominant, multisystem genetic disorder with wide phenotypic variability caused by mutations in the Notch signaling pathway, specifically from mutations in either the Jagged1 (JAG1) or NOTCH2 gene. The range of clinical features in ALGS can involve various organ systems including the liver, heart, eyes, skeleton, kidney, and vasculature. Despite the genetic mutations being well-defined, there is variable expressivity and individuals with the same mutation may have different clinical phenotypes.
    Areas covered: While no clear genotype-phenotype correlation has been identified in ALGS, this review will summarize what is currently known about the genotype-phenotype relationship and how this relationship influences the treatment of the multisystemic disorder. This review includes discussion of numerous studies which have focused on describing the genotype-phenotype relationship of different organ systems in ALGS as well as relevant basic science and population studies of ALGS. A thorough literature search was completed via the PubMed and National Library of Medicine GeneReviews databases including dates from 1969, when ALGS was first identified, to February 2023.
    Expert opinion: The genetics of ALGS are well defined; however, ongoing investigation to identify genotype-phenotype relationships as well as genetic modifiers as potential therapeutic targets is needed. Clinicians and patients alike would benefit from identification of a correlation to aid in diagnostic evaluation and management.
    MeSH term(s) Humans ; Alagille Syndrome/diagnosis ; Alagille Syndrome/genetics ; Alagille Syndrome/therapy ; Mutation ; Phenotype ; Genotype
    Language English
    Publishing date 2023-09-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2481021-6
    ISSN 1747-4132 ; 1747-4124
    ISSN (online) 1747-4132
    ISSN 1747-4124
    DOI 10.1080/17474124.2023.2255518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Assessment of dietary interventions including low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet as management for fructose intolerance.

    Lin, Henry C / Batiuk, Elizabeth / Hunter, Anna K

    Journal of pediatric gastroenterology and nutrition

    2024  Volume 78, Issue 3, Page(s) 548–554

    Abstract: Objectives: Abdominal pain remains one of the most common referral reasons to pediatric gastroenterology. Dietary intolerances are often considered but due to various factors are hardly pursued. We observed that diet review in large number of children ... ...

    Abstract Objectives: Abdominal pain remains one of the most common referral reasons to pediatric gastroenterology. Dietary intolerances are often considered but due to various factors are hardly pursued. We observed that diet review in large number of children with abdominal pain was high in sugary foods which led to food intolerance investigation and dietary intervention.
    Methods: A retrospective review was conducted of patients presenting with abdominal pain, diarrhea, or vomiting and negative GI evaluation, who underwent fructose breath testing. Patients younger than 20 years old who were seen between June 1, 2018 and March 1, 2021 were included. Statistical analysis was performed in R.
    Results: There were 110 pediatric patients during the study period who underwent fructose breath testing, with 31% male and 69% female. The average age was 12.14 ± 4.01 years, and the average BMI was 21.21 ± 6.12. Abdominal pain was the most common presenting symptom (74.5%) followed by diarrhea and vomiting. Seventy-seven patients (70%) had a positive fructose breath test and were diagnosed with dietary intolerance to fructose. The 56 (67.5%) of those patients experienced symptoms during the breath test. Forty-three patients improved with dietary intervention. Twenty-seven on low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet and 16 on other diets.
    Conclusions: Based on analysis of our cohort of children with abdominal pain and high incidence of fructose intolerance as well as improvement in symptoms, following dietary changes, this condition should be considered and treated. Further investigation is needed to improve diagnostic testing but also into understanding mechanisms behind symptom presentation in this population.
    MeSH term(s) Humans ; Male ; Female ; Child ; Adolescent ; Young Adult ; Adult ; Disaccharides ; Fructose Intolerance/diagnosis ; Fructose Intolerance/therapy ; Fructose Intolerance/complications ; Monosaccharides ; Irritable Bowel Syndrome/complications ; Diet ; Oligosaccharides ; Abdominal Pain/complications ; Diarrhea/etiology ; Fructose ; Vomiting/complications ; Fermentation ; Polymers
    Chemical Substances Disaccharides ; polyol ; Monosaccharides ; Oligosaccharides ; Fructose (30237-26-4) ; Polymers
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1002/jpn3.12113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Design and Implementation of a Program Development Practicum for Faculty Education and Advancement of Clinical Programs.

    Ward, Pam / Lin, Henry C

    Pediatric reports

    2022  Volume 14, Issue 4, Page(s) 457–463

    Abstract: Physicians are often tasked to develop and lead collaborative, program development efforts but many have limited formal training. We designed and evaluated a professional development workshop series to provide our faculty members with a framework and ... ...

    Abstract Physicians are often tasked to develop and lead collaborative, program development efforts but many have limited formal training. We designed and evaluated a professional development workshop series to provide our faculty members with a framework and tools for the development of clinical programs: the Program Development Practicum (PDP). Faculty identified a clinical program of focus and for each clinical program identified, a program proposal, SBAR communication (situation, background, assessment, recommendation), executive summary, 1-min elevator pitch, and budget was developed. Five clinical programs were identified for improvement including: Inflammatory Bowel Disease, Celiac Disease, Transition of Care, Integrative Health Clinic, and Endoscopic Procedures. At the conclusion of the PDP, these programs were presented to key hospital leaders and resulted in an investment of resource support. Faculty also reported increased understanding of overall program development with the largest gains in knowledge in proposal writing and marketing. Overall, the PDP allowed for a revamp of key clinical services and faculty clarity on resource availability and expectations. We plan to continue with annual engagement of hospital leaders to share updates.
    Language English
    Publishing date 2022-10-31
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2036-749X
    ISSN 2036-749X
    DOI 10.3390/pediatric14040054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Desulfovibrio

    Singh, Sudha B / Carroll-Portillo, Amanda / Lin, Henry C

    Microorganisms

    2023  Volume 11, Issue 7

    Abstract: ... ...

    Abstract Desulfovibrio
    Language English
    Publishing date 2023-07-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11071772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Diversity of Bacteriophages in the Human Gut.

    Carroll-Portillo, Amanda / Lin, Derek M / Lin, Henry C

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2738, Page(s) 17–30

    Abstract: Bacteriophages, commonly referred to as phages, are viruses that infect bacteria and are among the most numerous microorganisms on the planet. They occur throughout nature occupying every habitat where their bacterial hosts can be found. Within these ... ...

    Abstract Bacteriophages, commonly referred to as phages, are viruses that infect bacteria and are among the most numerous microorganisms on the planet. They occur throughout nature occupying every habitat where their bacterial hosts can be found. Within these communities, phages are responsible for shaping the bacterial community structure and function through their interactions. Phages shape the community structure and function within the human gut but are also able to influence the human host. As such, there is increased interest in understanding the composition and activity of the gastrointestinal phages, although these studies have been hindered by the difficulties accompanying the study of the human gut. Here, we summarize the methods and findings pertaining to the diversity of the human gastrointestinal phages.
    MeSH term(s) Humans ; Bacteriophages/genetics ; Gastrointestinal Tract/virology
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3549-0_2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Resolution of Anastomotic Ulceration and Profound Bleeding by Endoscopic Cauterization and Oral Budesonide.

    Xi, Dong / Hakar, Melanie / Davis, Jessica / Lin, Henry

    JPGN reports

    2023  Volume 4, Issue 3, Page(s) e328

    Abstract: Anastomotic ulceration is a known complication of short gut syndrome, which can be complicated by concurrent iron deficiency and chronic bleeding. Diagnosis is confirmed through endoscopy, typically performed for the investigation of severe anemia. ... ...

    Abstract Anastomotic ulceration is a known complication of short gut syndrome, which can be complicated by concurrent iron deficiency and chronic bleeding. Diagnosis is confirmed through endoscopy, typically performed for the investigation of severe anemia. Inflammatory colitis in short gut syndrome has been previously reported; therefore, it is important to treat both ulceration and inflammation. Currently, no effective therapies are available. Herein, we describe the case of a child with short gut syndrome who subsequently developed anastomotic ulcers with recurrent severe bleeding and was successfully treated with endoscopic argon plasma cauterization for circumferential ulcerations, followed by a prolonged course of oral enteric budesonide. This intervention could be a potential and beneficial nonsurgical treatment for anastomotic ulceration.
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Case Reports
    ISSN 2691-171X
    ISSN (online) 2691-171X
    DOI 10.1097/PG9.0000000000000328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Resolution of Pruritus in a Child With Alagille Syndrome Treated With Maralixibat for Seven Years: Durable Response and Discontinuation of Other Medications.

    Garcia, Amy / Hsu, Evelyn / Lin, Henry C

    JPGN reports

    2023  Volume 4, Issue 3, Page(s) e335

    Abstract: Intractable pruritus is one of the most prominent and debilitating features of Alagille syndrome. Maralixibat is the first US Food and Drug Administration-approved drug for the treatment of cholestatic pruritus in children with Alagille syndrome aged 3 ... ...

    Abstract Intractable pruritus is one of the most prominent and debilitating features of Alagille syndrome. Maralixibat is the first US Food and Drug Administration-approved drug for the treatment of cholestatic pruritus in children with Alagille syndrome aged 3 months and older. Clinical trials of maralixibat have reported follow-up to 4 years and reported a ≥1-pt reduction using the Itch-Reported Outcome (Observer) (ItchRO[Obs]) instrument (0-4 scale), as this decrease was previously defined as a clinically meaningful improvement in pruritus; participants in clinical trials were expected to be maintained on stable doses of antipruritic agents. We report on a patient with 3 notable features: (1) complete resolution of her pruritus; (2) durability of this response for over 7 years; and (3) ability to discontinue all other antipruritic medications.
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Case Reports
    ISSN 2691-171X
    ISSN (online) 2691-171X
    DOI 10.1097/PG9.0000000000000335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Possible Hepatic Torsion, a Pediatric Patient With Polycystic Kidney Disease.

    Diefendorf, Caitlin M / Phelps, Andrew S / Lin, Henry C

    Clinical pediatrics

    2023  Volume 63, Issue 4, Page(s) 568–572

    MeSH term(s) Humans ; Child ; Polycystic Kidney Diseases/complications ; Polycystic Kidney Diseases/diagnosis ; Liver ; Liver Diseases/diagnosis ; Liver Diseases/diagnostic imaging ; Kidney
    Language English
    Publishing date 2023-06-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231180180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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