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  1. Article ; Online: The eQTL analysis to discover unique eGFR-related SNPs for the Taiwanese population.

    Wu, Ping-Hsun / Lin, Johnathan / Kuo, Mei-Chuan / Yu, Sung-Huan

    Journal of nephrology

    2023  Volume 37, Issue 1, Page(s) 249–252

    MeSH term(s) Humans ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Genome-Wide Association Study
    Language English
    Publishing date 2023-10-19
    Publishing country Italy
    Document type Letter
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-023-01793-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3369: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Benchmarking differential expression, imputation and quantification methods for proteomics data.

    Lin, Miao-Hsia / Wu, Pei-Shan / Wong, Tzu-Hsuan / Lin, I-Ying / Lin, Johnathan / Cox, Jürgen / Yu, Sung-Huan

    Briefings in bioinformatics

    2022  Volume 23, Issue 3

    Abstract: Data analysis is a critical part of quantitative proteomics studies in interpreting biological questions. Numerous computational tools for protein quantification, imputation and differential expression (DE) analysis were generated in the past decade and ... ...

    Abstract Data analysis is a critical part of quantitative proteomics studies in interpreting biological questions. Numerous computational tools for protein quantification, imputation and differential expression (DE) analysis were generated in the past decade and the search for optimal tools is still going on. Moreover, due to the rapid development of RNA sequencing (RNA-seq) technology, a vast number of DE analysis methods were created for that purpose. The applicability of these newly developed RNA-seq-oriented tools to proteomics data remains in doubt. In order to benchmark these analysis methods, a proteomics dataset consisting of proteins derived from humans, yeast and drosophila, in defined ratios, was generated in this study. Based on this dataset, DE analysis tools, including microarray- and RNA-seq-based ones, imputation algorithms and protein quantification methods were compared and benchmarked. Furthermore, applying these approaches to two public datasets showed that RNA-seq-based DE tools achieved higher accuracy (ACC) in identifying DEPs. This study provides useful guidelines for analyzing quantitative proteomics datasets. All the methods used in this study were integrated into the Perseus software, version 2.0.3.0, which is available at https://www.maxquant.org/perseus.
    MeSH term(s) Algorithms ; Benchmarking ; Proteins ; Proteomics/methods ; Sequence Analysis, RNA ; Software
    Chemical Substances Proteins
    Language English
    Publishing date 2022-04-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2068142-2
    ISSN 1477-4054 ; 1467-5463
    ISSN (online) 1477-4054
    ISSN 1467-5463
    DOI 10.1093/bib/bbac138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6262: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  3. Article ; Online: Large benign de novo conjunctival hemangioma in an 11-year-old boy: case report and literature review.

    Godfrey, Kyle J / Kinori, Michael / Lin, Johnathan H / Snyder, Vivian S / Granet, David B / Heichel, Christopher W / Robbins, Shira L

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus

    2016  Volume 20, Issue 5, Page(s) 462–464

    Abstract: Benign hemangiomas are rare vascular tumors of the conjunctiva that typically present clinically in the first few weeks of life and resolve spontaneously. De novo presentation later in childhood has not been well documented. We present the unusual case ... ...

    Abstract Benign hemangiomas are rare vascular tumors of the conjunctiva that typically present clinically in the first few weeks of life and resolve spontaneously. De novo presentation later in childhood has not been well documented. We present the unusual case of an 11-year-old boy with a rapidly growing benign de novo conjunctival hemangioma that was treated with surgical excision.
    MeSH term(s) Biomarkers, Tumor/metabolism ; Child ; Conjunctival Neoplasms/metabolism ; Conjunctival Neoplasms/pathology ; Conjunctival Neoplasms/surgery ; Hemangioma/metabolism ; Hemangioma/pathology ; Hemangioma/surgery ; Humans ; Male ; Neoplasm Proteins/metabolism ; Ophthalmologic Surgical Procedures
    Chemical Substances Biomarkers, Tumor ; Neoplasm Proteins
    Language English
    Publishing date 2016-09-16
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1412476-2
    ISSN 1528-3933 ; 1091-8531
    ISSN (online) 1528-3933
    ISSN 1091-8531
    DOI 10.1016/j.jaapos.2016.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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