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  1. Article ; Online: General autophagy-dependent and -independent lipophagic processes collaborate to regulate the overall level of lipophagy in yeast.

    Kang, Na / Tan, Jinling / Yan, Sisi / Lin, Leiying / Gao, Qiang

    Autophagy

    2024  

    Abstract: Lipophagy in the ... ...

    Abstract Lipophagy in the yeast
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2024.2325297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6741: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Fatty Acyl Coenzyme A Synthetase Fat1p Regulates Vacuolar Structure and Stationary-Phase Lipophagy in Saccharomyces cerevisiae.

    Qiu, Fan / Kang, Na / Tan, Jinling / Yan, Sisi / Lin, Leiying / Cai, Lipeng / Goodman, Joel M / Gao, Qiang

    Microbiology spectrum

    2023  Volume 11, Issue 1, Page(s) e0462522

    Abstract: During yeast stationary phase, a single spherical vacuole (lysosome) is created by the fusion of several small ones. Moreover, the vacuolar membrane is reconstructed into two distinct microdomains. Little is known, however, about how cells maintain ... ...

    Abstract During yeast stationary phase, a single spherical vacuole (lysosome) is created by the fusion of several small ones. Moreover, the vacuolar membrane is reconstructed into two distinct microdomains. Little is known, however, about how cells maintain vacuolar shape or regulate their microdomains. Here, we show that Fat1p, a fatty acyl coenzyme A (acyl-CoA) synthetase and fatty acid transporter, and not the synthetases Faa1p and Faa4p, is essential for vacuolar shape preservation, the development of vacuolar microdomains, and cell survival in stationary phase of the yeast Saccharomyces cerevisiae. Furthermore, Fat1p negatively regulates general autophagy in both log- and stationary-phase cells. In contrast, Fat1p promotes lipophagy, as the absence of
    MeSH term(s) Saccharomyces cerevisiae/metabolism ; Vacuoles/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Fatty Acids/metabolism ; Coenzyme A Ligases/genetics ; Coenzyme A Ligases/metabolism ; Autophagy ; Fatty Acid Transport Proteins/metabolism
    Chemical Substances Saccharomyces cerevisiae Proteins ; Fatty Acids ; Coenzyme A Ligases (EC 6.2.1.-) ; FAT1 protein, S cerevisiae ; Fatty Acid Transport Proteins
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.04625-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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