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Article ; Online: The Association of Malnutrition and Health-Related Factors among 474,467 Older Community-Dwellers: A Population-Based Data Mining Study in Guangzhou, China.

Lin, Wei-Quan / Xiao, Ting / Fang, Ying-Ying / Sun, Min-Ying / Yang, Yun-Ou / Chen, Jia-Min / Ou, Chun-Quan / Liu, Hui

2024 Volume 16, Issue 9

Abstract: Background: This study aimed to examine the prevalence and associated factors of malnutrition in older community-dwellers and explore the interaction between associated factors.: Methods: A total of 474,467 older community-dwellers aged 65 or above ... ...

Abstract	Background: This study aimed to examine the prevalence and associated factors of malnutrition in older community-dwellers and explore the interaction between associated factors. Methods: A total of 474,467 older community-dwellers aged 65 or above were selected in Guangzhou, China. We used a two-step methodology to detect the associated factors of malnutrition and constructed logistic regression models to explore the influencing factors and interactive effects on three patterns of malnutrition. Results: The prevalence of malnutrition was 22.28%. Older adults with both hypertension and diabetes (RERI = 0.13), both meat or fish diet and hypertension (RERI = 0.79), and both meat or fish diet and diabetes (RERI = 0.81) had positive additive interaction effects on the risk of obesity, whereas those on a vegetarian diet with hypertension (RERI = -0.25) or diabetes (RERI = -0.19) had negative additive interaction effects. Moreover, the interactions of physical activity with a meat or fish diet (RERI = -0.84) or dyslipidemia (RERI = -0.09) could lower the risk of obesity. Conclusions: Malnutrition was influenced by different health factors, and there were interactions between these influencing factors. Pertinent dietary instruction should be given according to different nutritional status indexes and the prevalence of metabolic diseases to avoid the occurrences of malnutrition among older adults.
MeSH term(s)	Humans ; Aged ; China/epidemiology ; Male ; Female ; Malnutrition/epidemiology ; Prevalence ; Hypertension/epidemiology ; Risk Factors ; Data Mining ; Aged, 80 and over ; Independent Living ; Nutritional Status ; Diabetes Mellitus/epidemiology ; Obesity/epidemiology ; Diet ; Exercise ; Logistic Models ; Dyslipidemias/epidemiology
Language	English
Publishing date	2024-04-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16091338
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Mononuclear Iron(II) Spin-Crossover Molecule Decorated by Photochromic Azobenzene Group.

Qiu, Jiang-Zhen / You, Yong / Yu, Ye / Chen, Zhuo-Fan / Guo, Cheng-Jie / Zhong, Yi-Ling / Lin, Wei-Quan / Shu, Xu-Gang

Molecules (Basel, Switzerland)

2022 Volume 27, Issue 5

Abstract: Aiming at constructing photoresponsive spin crossover (SCO) behavior, herein we designed a new ligand Abtz (Abtz = ( ...

Abstract	Aiming at constructing photoresponsive spin crossover (SCO) behavior, herein we designed a new ligand Abtz (Abtz = (
Language	English
Publishing date	2022-02-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules27051571
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Article ; Online: Stereoisomeric coordination polymers based on facial and meridional six-coordinate dysprosium(III ).

Lin, Wei-Quan / Wang, Dan-Ru / Long, Wei-Jian / Lin, Li-Shan / Tao, Ze-Xian / Liu, Jun-Liang / Liu, Zhao-Qing / Leng, Ji-Dong

Dalton transactions (Cambridge, England : 2003)

2022 Volume 51, Issue 13, Page(s) 5195–5202

Abstract: Due to the small differences in the chemical properties ... ...

Abstract	Due to the small differences in the chemical properties of
MeSH term(s)	Crystallography, X-Ray ; Dysprosium/chemistry ; Lanthanoid Series Elements/chemistry ; Polymers/chemistry ; Stereoisomerism
Chemical Substances	Lanthanoid Series Elements ; Polymers ; Dysprosium (1D4N45714Q)
Language	English
Publishing date	2022-03-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/d2dt00334a
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Article ; Online: Slow magnetic relaxation of mononuclear complexes based on uncommon Kramers lanthanide ions Ce

Leng, Ji-Dong / Hua, Qiu-Yan / Liu, Wen-Ting / Tao, Ze-Xian / Tan, Nai-Wen / Wang, Yu-Fei / Lin, Wei-Quan

Dalton transactions (Cambridge, England : 2003)

2022 Volume 51, Issue 33, Page(s) 12661–12669

Abstract: Based on the uncommon Kramers ions ... ...

Abstract	Based on the uncommon Kramers ions Ce
Language	English
Publishing date	2022-08-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/d2dt00766e
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Article ; Online: Prevalence, distribution, accumulation, and risk of environmental corticosteroids and estrogens in biofilms from the Pearl River Delta

Gong, Jian / Yang, Ke-Xin / Lin, Can-Yuan / Li, Qiang / Han, Chŏng / Tao, Wei / Huang, Ying / Lin, Wei-Quan / Wu, Cui-Qin / Zhang, Shu-Han / Wang, De-Xin

Environmental Pollution. 2023 Oct., v. 334 p.122192-

2023

Abstract: Biofilms play a significant role in the biogeochemical processing of organic matter and the environmental fate of emerging pollutants. In this study, we investigated the occurrence and distribution of 32 endocrine-disrupting chemicals (EDCs), including ... ...

Abstract	Biofilms play a significant role in the biogeochemical processing of organic matter and the environmental fate of emerging pollutants. In this study, we investigated the occurrence and distribution of 32 endocrine-disrupting chemicals (EDCs), including 24 environmental corticosteroids (ECs) and 8 environmental estrogens (EEs), in natural biofilms from the Pearl River system. Their association between biofilms and water and environmental risk were assessed. The ECs and EEs ubiquitously occurred in the biofilms, ranging from <0.61–6.57 ng/g and <0.8–2535 ng/g, respectively. Temporally, there was no obvious variance in either ECs or EEs in the biofilms during the winter and summer, and their concentrations exhibited a spatial trend of upward to midstream, descending downstream, and then seaward attenuation at the estuary. For ECs and EEs, the similar levels of field-derived bioconcentration factors (BCFs) (logarithm values: 2.42–2.86 and 2.72–2.98, respectively) and biofilm organic carbon-normalized partitioning coefficients (Kbₒc) (3.39–3.69 and 3.35–3.95) suggest the comparable potential of accumulation and sorption by biofilms between these two classes of EDCs. In addition, higher values of BCF and Kbₒc for the EEs were found in winter and were correspondingly comparable to their distribution coefficients (Kd) and Kₒc derived from suspended particles and sediment, revealing that biofilms are a competitive environmental compartment for capturing EDCs, particularly during the mature period. A positive logKbₒc-logKₒw relationship suggests hydrophobic partitioning as a primary interaction mechanism between the biofilm and EEs. Moreover, high risks from biofilm-associated ECs and EEs might have posed to the fluvial ecosystem. This study provides original insights into the occurrence, fate, and risk of ECs in natural biofilms for the first time and demonstrates that biofilms may not only serve as reservoirs but also serve as sentinels for fluvial EDC contamination. These results contribute to the further understanding of the behavior and fate of EDCs in aquatic environments.
Keywords	adrenal cortex hormones ; bioaccumulation ; biofilm ; ecosystems ; environmental fate ; estuaries ; hydrophobicity ; organic matter ; pollution ; risk ; river deltas ; rivers ; sediments ; sorption ; summer ; variance ; winter ; Corticosteroid ; Endocrine-disrupting chemicals (EDCs) ; Distribution ; Partition ; River ; ADS ; AM ; BC ; BCF ; BDN ; BET ; BPA ; CBB ; CBP ; COR ; CORT ; CRL ; DC ; DCA ; DES ; DEX ; DO ; DR ; ECs ; E1 ; E2 ; E3 ; EE2 ; EDCs ; EEs ; EPS ; FCA ; FLA ; FML ; FMS ; FN ; FTP ; GCs ; HOCs ; HQ ; Kd ; Koc ; Kow ; LOD ; LOQ ; MCs ; MEC ; MPNL ; MSTFA ; NP ; OP ; OC ; PEs ; PNEC ; PNL ; PNS ; PRD ; QSAR ; RSDs ; SEs ; SPM ; SW ; TCA ; TOC ; TRI ; WWTP ; ZR
Language	English
Dates of publication	2023-10
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2023.122192
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Article ; Online: A Layered Aluminophosphate [C

Qiu, Jiang-Zhen / Guo, Cheng-Jie / Wu, Qinwu / Liao, Pei-Yu / Deng, Jinyu / Chen, Zhuo-Fan / Yao, Suyang / Lin, Wei-Quan / Jiang, Jiuxing

Inorganic chemistry

2023 Volume 62, Issue 42, Page(s) 17052–17056

Abstract: Designing and innovating organic structure-directing agents is the key to synthesizing novel molecular sieve structures. Herein, we design a novel carbazolyl-modified template and further synthesize a two-dimensional layered aluminophosphate with [ ... ...

Abstract	Designing and innovating organic structure-directing agents is the key to synthesizing novel molecular sieve structures. Herein, we design a novel carbazolyl-modified template and further synthesize a two-dimensional layered aluminophosphate with [C
Language	English
Publishing date	2023-10-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1484438-2
ISSN	1520-510X ; 0020-1669
ISSN (online)	1520-510X
ISSN	0020-1669
DOI	10.1021/acs.inorgchem.3c02837
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Article ; Online: Prevalence of falls, injury from falls and associations with chronic diseases among community-dwelling older adults in Guangzhou, China: a cross-sectional study.

Lin, Wei-Quan / Lin, Lin / Sun, Si-Yu / Yuan, Le-Xin / Sun, Min-Ying / Wang, Chang / Chen, Jia-Min / Li, Yao-Hui / Zhou, Qin / Wu, Di / Huang, Ting-Yuan / Liang, Bo-Heng / Liu, Hui

Frontiers in public health

2023 Volume 11, Page(s) 1251858

Abstract: Introduction: As a developing country with the largest older adult population in the world, strengthening the research on falls among the older adults is undoubtedly an urgent item in China. This study aimed to explore the prevalence and risk factors ... ...

Abstract	Introduction: As a developing country with the largest older adult population in the world, strengthening the research on falls among the older adults is undoubtedly an urgent item in China. This study aimed to explore the prevalence and risk factors associated with falls and injury from falls among community-dwelling older adults in Guangzhou, China, particularly focusing on their associations with chronic diseases. Methods: A total of 1,629 participants aged 65 years and above were selected from 11 counties in Guangzhou by the multi-stage stratified random sampling method in 2021. Socio-demographic characteristics, health and lifestyle factors, the status of falls, and injury from falls were measured by structured questionnaires through face-to-face interviews. Chi-square tests and logistic regression analysis were used to identify factors associated with falls and injury from falls. Chord diagrams were used to explore their associations with chronic diseases. Results: A total of 251 participants (15.41%, 95% CI: 13.98%-17.25%) reported falls, and 162 participants (9.46%, 95% CI:7.72%-11.55%) indicated an injury from falls. Logistic regression analysis showed the results as follows: female patients (adjusted OR = 1.721, 95% CI: 1.681-1.761) aged ≥80 years (1.910, 1.847-1.975), unemployed (1.226, 1.171-1.284), uninsured (1.555, 1.448-1.671), average monthly household income of 2,001-4,000 CNY (1.878, 1.827-1.930), number of services provided by the community health center ≥13 times per year (1.428, 1.383-1.475), illness within 2 weeks (1.633, 1.595-1.672), high-intensity physical activity (2.254, 2.191-2.32), sedentary (1.094, 1.070-1.117), and number of chronic disease illnesses ≥3 (1.930, 1.870-1.993). Meanwhile, those risk factors were also associated with injury from falls. The older adults with medium-intensity physical activity were at lower risk (0.721, 0.705-0.737) of falls and higher risk (1.086, 1.057-1.117) of being injured from falls. Chord diagrams showed the correlations between chronic diseases and falls and injury from falls among community-dwelling older adults in Guangzhou, China. Conclusion: The high prevalence of falls is found among community-dwelling older adults in Guangzhou, China, which is related to multiple factors such as demographic variables, lifestyle, and health status, especially for chronic diseases. Therefore, targeted interventions should be developed and implemented urgently.
MeSH term(s)	Humans ; Female ; Aged ; Independent Living ; Cross-Sectional Studies ; Prevalence ; China/epidemiology ; Chronic Disease
Language	English
Publishing date	2023-09-15
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1251858
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Article ; Online: Suspended particulate matter-associated environmental corticosteroids in the Pearl River, China: Occurrence, distribution, and partitioning.

Gong, Jian / Zhou, Yong-Shun / Lin, Can-Yuan / Li, Qiang / Han, Chong / Yang, Ke-Xin / Huang, Ying / Lin, Wei-Quan / Wu, Cui-Qin / Zhang, Shu-Han / Huang, Jia-Yu

The Science of the total environment

2023 Volume 884, Page(s) 163701

Abstract: Suspended particulate matter (SPM) plays an important role in the geochemical behavior and fate of organic micropollutants in aquatic environments. However, the presence of trace emerging endocrine disruptors such as environmental corticosteroids (ECs) ... ...

Abstract	Suspended particulate matter (SPM) plays an important role in the geochemical behavior and fate of organic micropollutants in aquatic environments. However, the presence of trace emerging endocrine disruptors such as environmental corticosteroids (ECs) in SPM is less well understood. This study focused on the occurrence, distribution, and partitioning of SPM-associated ECs in the Pearl River system, China. Ubiquitous particulate ECs were found in the surface water of the rivers at average concentrations (dry weight) between 0.46 ng/g (flumethasone) and 8.83 ng/g (clobetasone butyrate). The total EC (∑ECs) concentrations of the 24 selected target compounds varied from <1.03 ng/g to 62.3 ng/g, with an average and median of 17.6 ng/g and 13.7 ng/g, respectively. Higher SPM-bound EC levels were commonly observed in winter (dry season), and spatially, their relatively high contamination in urban tributary networks decreased while flowing to mainstreams and then gradually attenuated from upstream to the estuary. Despite the approximately 90 % mass distribution of ∑ECs in the aqueous phase, approximately 50 % of their effect burden was derived from the suspended particulate fractions. For the first time, in situ SPM-water partitioning coefficients (K
MeSH term(s)	Rivers/chemistry ; Water Pollutants, Chemical/analysis ; Particulate Matter/analysis ; Adrenal Cortex Hormones ; Water ; China ; Dust ; Environmental Monitoring ; Geologic Sediments/chemistry
Chemical Substances	Water Pollutants, Chemical ; Particulate Matter ; Adrenal Cortex Hormones ; Water (059QF0KO0R) ; Dust
Language	English
Publishing date	2023-04-25
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.163701
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Article ; Online: Prevalence, distribution, accumulation, and risk of environmental corticosteroids and estrogens in biofilms from the Pearl River Delta.

Gong, Jian / Yang, Ke-Xin / Lin, Can-Yuan / Li, Qiang / Han, Chong / Tao, Wei / Huang, Ying / Lin, Wei-Quan / Wu, Cui-Qin / Zhang, Shu-Han / Wang, De-Xin

Environmental pollution (Barking, Essex : 1987)

2023 Volume 334, Page(s) 122192

Abstract	Biofilms play a significant role in the biogeochemical processing of organic matter and the environmental fate of emerging pollutants. In this study, we investigated the occurrence and distribution of 32 endocrine-disrupting chemicals (EDCs), including 24 environmental corticosteroids (ECs) and 8 environmental estrogens (EEs), in natural biofilms from the Pearl River system. Their association between biofilms and water and environmental risk were assessed. The ECs and EEs ubiquitously occurred in the biofilms, ranging from <0.61-6.57 ng/g and <0.8-2535 ng/g, respectively. Temporally, there was no obvious variance in either ECs or EEs in the biofilms during the winter and summer, and their concentrations exhibited a spatial trend of upward to midstream, descending downstream, and then seaward attenuation at the estuary. For ECs and EEs, the similar levels of field-derived bioconcentration factors (BCFs) (logarithm values: 2.42-2.86 and 2.72-2.98, respectively) and biofilm organic carbon-normalized partitioning coefficients (K
MeSH term(s)	Estrogens ; Prevalence ; Ecosystem ; Water Pollutants, Chemical/analysis ; Environmental Monitoring/methods ; Adrenal Cortex Hormones ; Endocrine Disruptors/analysis ; Biofilms ; China
Chemical Substances	Estrogens ; Water Pollutants, Chemical ; Adrenal Cortex Hormones ; Endocrine Disruptors
Language	English
Publishing date	2023-07-12
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2023.122192
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Article ; Online: Targeted Next-Generation Sequencing of Circulating Tumor DNA Mutations among Metastatic Breast Cancer Patients.

Sun, Min-Ying / Lin, Fang-Qin / Chen, Lu-Jia / Li, Hong / Lin, Wei-Quan / Du, Hong-Yan / Yang, Xue-Xi / Li, Ming

Current oncology (Toronto, Ont.)

2021 Volume 28, Issue 4, Page(s) 2326–2336

Abstract: Liquid biopsy through the detection of circulating tumor DNA (ctDNA) has potential advantages in cancer monitoring and prediction. However, most previous studies in this area were performed with a few hotspot genes, single time point detection, or ... ...

Abstract	Liquid biopsy through the detection of circulating tumor DNA (ctDNA) has potential advantages in cancer monitoring and prediction. However, most previous studies in this area were performed with a few hotspot genes, single time point detection, or insufficient sequencing depth. In this study, we performed targeted next-generation sequencing (NGS) with a customized panel in metastatic breast cancer (MBC) patients. Fifty-four plasma samples were taken before chemotherapy and after the third course of treatment for detection and analysis. Paired lymphocytes were also included to eliminate clonal hematopoiesis (CH)-related alternatives. A total of 1182 nonsynonymous mutations in 419 genes were identified. More ctDNA mutations were detected in patients with tumors > 3 cm (
MeSH term(s)	Biomarkers, Tumor/genetics ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Circulating Tumor DNA/genetics ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation
Chemical Substances	Biomarkers, Tumor ; Circulating Tumor DNA
Language	English
Publishing date	2021-06-24
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1236972-x
ISSN	1718-7729 ; 1198-0052
ISSN (online)	1718-7729
ISSN	1198-0052
DOI	10.3390/curroncol28040214
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