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  1. AU="Lin, Xianyao"
  2. AU="Chronister, A"
  3. AU="Noble, Andrew"
  4. AU="Mondal, M M" AU="Mondal, M M"
  5. AU="Julio César García Casallas"
  6. AU="Kerstin Vehring"
  7. AU="Oishi, Hisashi"
  8. AU="Qin, Jiong"
  9. AU="Dumbleton, Jennifer S"
  10. AU="Le Cam Bouveret, Nancy"
  11. AU="Shetty, Sharanya B"
  12. AU="Paten, Benedict"
  13. AU="Molokhia, Ashraf"
  14. AU="Zirone, Eleonora"
  15. AU="Tong, Wenxia"
  16. AU="Chalira, Davie"
  17. AU="Hodane Yonis"
  18. AU="Boggiano, César"
  19. AU="Gainor, Justin F"
  20. AU="Scurr, David J"
  21. AU="Mahuran, Don J"
  22. AU="Dominguez, Dana A"
  23. AU=Mota Gustavo R
  24. AU="Pandey, Gayathri"
  25. AU=Kiesslich Ralf
  26. AU="Wiskar, Katie"
  27. AU=Bennett Kaila M.
  28. AU=Bacci Jennifer L
  29. AU="Wildman, Ricky D."
  30. AU="Alshibani, Nouf"
  31. AU="Loens, Christopher"
  32. AU="Friedman, Lawrence M."
  33. AU="Johnstone, Damian"
  34. AU="Maleki, Shayan"
  35. AU="G. E-S. Batiha"
  36. AU=Johnson Guyla G
  37. AU="Patel, Parth H"
  38. AU="Manassero, Carlo"
  39. AU="Kirk, Tom"
  40. AU="Bezabih, Yihienew Mequanint"
  41. AU="Hirsinger, Estelle"
  42. AU="Robles-Musso Castillo, Emilio"
  43. AU="Vahdatihassani, Faezeh"
  44. AU="Maria Pala"
  45. AU=Singh Indra
  46. AU="Gallacher, Nicola"
  47. AU="Chen, Pei-Min"
  48. AU=Andre L
  49. AU="Aleksandra I. Pivovarova"
  50. AU="Cruz, Thainá Gabriele Camargo da"
  51. AU="Atkins, Peter"

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  1. Artikel ; Online: Clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in children in China.

    Song, Wen / Shan, Qingwen / Qiu, Yue / Lin, Xianyao / Zhu, Chunhui / Zhuo, Zhiqiang / Wang, Caihong / Tong, Jianning / Li, Rui / Wan, Chaomin / Zhu, Yu / Chen, Minxia / Xu, Yi / Lin, Daojiong / Wu, Shouye / Jia, Chunmei / Gao, Huiling / Yang, Junwen / Zhao, Shiyong /
    Zeng, Mei

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

    2022  Band 41, Heft 10, Seite(n) 1215–1225

    Abstract: Invasive Salmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoid Salmonella infections is increasingly recognized with ...

    Abstract Invasive Salmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoid Salmonella infections is increasingly recognized with the improvement of laboratory detection capacity and techniques. A retrospective multicenter study was conducted to analyze the clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in hospitalized children in China during 2016-2018. A total of 130 children with invasive Salmonella infections were included with the median age of 12 months (range: 1-144 months). Seventy-nine percent of cases occurred between May and October. Pneumonia was the most common comorbidity in 33 (25.4%) patients. Meningitis and septic arthritis caused by nontyphoidal Salmonella (NTS) infections occurred in 12 (9.2%) patients and 5 (3.8%) patients. Patients < 12 months (OR: 16.04) and with septic shock (OR: 23.4), vomit (OR: 13.33), convulsion (OR: 15.86), C-reactive protein (CRP) ≥ 40 g/L (OR: 5.56), and a higher level of procalcitonin (PCT) (OR: 1.05) on admission were statistically associated to an increased risk of developing meningitis. Compared to 114 patients with NTS infections, 16 patients with typhoid fever presented with higher levels of CRP and PCT (P < 0.05). The rates of resistance to ampicillin, sulfamethoxazole/trimethoprim, ciprofloxacin, and ceftriaxone among Salmonella Typhi and NTS isolates were 50% vs 57.3%, 9.1% vs 24.8%, 0% vs 11.2%, and 0% vs 9.9%, respectively. NTS has been the major cause of invasive Salmonella infections in Chinese children and can result in severe diseases. Antimicrobial resistance among NTS was more common.
    Mesh-Begriff(e) Ampicillin ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; C-Reactive Protein ; Ceftriaxone ; Child ; Child, Preschool ; China/epidemiology ; Ciprofloxacin ; Drug Resistance, Bacterial ; Humans ; Infant ; Microbial Sensitivity Tests ; Procalcitonin ; Salmonella ; Salmonella Infections/epidemiology ; Salmonella Infections/microbiology ; Trimethoprim, Sulfamethoxazole Drug Combination ; Typhoid Fever/drug therapy
    Chemische Substanzen Anti-Bacterial Agents ; Procalcitonin ; Ciprofloxacin (5E8K9I0O4U) ; Ceftriaxone (75J73V1629) ; Ampicillin (7C782967RD) ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2) ; C-Reactive Protein (9007-41-4)
    Sprache Englisch
    Erscheinungsdatum 2022-08-30
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Multicenter Study
    ZDB-ID 603155-9
    ISSN 1435-4373 ; 0934-9723 ; 0722-2211
    ISSN (online) 1435-4373
    ISSN 0934-9723 ; 0722-2211
    DOI 10.1007/s10096-022-04476-7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1732: Hefte anzeigen Standort:
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  2. Artikel ; Online: Intestinal detoxification time of hand-foot-and-mouth disease in children with EV71 infection and the related factors.

    Teng, Shu / Wei, Yi / Zhao, Shi-Yong / Lin, Xian-Yao / Shao, Qi-Min / Wang, Juan

    World journal of pediatrics : WJP

    2015  Band 11, Heft 4, Seite(n) 380–385

    Abstract: Background: Hand-foot-and-mouth disease (HFMD) is a common pediatric infectious disease caused by a variety of intestinal viruses. Enterovirus 71 (EV71) is the primary pathogen that might cause severe symptoms and even death in children with HFMD. This ... ...

    Abstract Background: Hand-foot-and-mouth disease (HFMD) is a common pediatric infectious disease caused by a variety of intestinal viruses. Enterovirus 71 (EV71) is the primary pathogen that might cause severe symptoms and even death in children with HFMD. This study aimed to investigate the intestinal detoxification time of HFMD children with EV71 infection and its related factors.
    Methods: Sixty-five HFMD children with EV71 infection were followed up. Their stool samples were collected once every 4 to 7 days. Viral nucleic acids were detected by fluorescent polymerase chain reaction until the results became negative. The positive rates of viral nucleic acids were analyzed by the Kaplan-Meier method. The Log-rank test and Cox-Mantel test were used to analyze factors affecting the HFMD children with EV71 infection.
    Results: On the 2nd, 4th, 6th and 10th week, the positive rates of viral nucleic acids in stool samples of the 65 children were 94.6%, 48.1%, 17.2% and 0, respectively. Univariate analysis showed that the intestinal detoxification time of the children were related to gender, pre-admission disease course, severity of disease, and use of steroids or gamma globulin (P<0.05). Multivariate analysis showed that the severity of disease was an independent factor affecting the intestinal detoxification time (P<0.05), with a relative risk of 2.418.
    Conclusions: The longest intestinal detoxification time of HFMD children with EV71 infection was 10 weeks. The severity of disease was an important factor affecting the intestinal detoxification time of HFMD children with EV71 infection. Severe HFMD children with EV71 infection had a longer intestinal detoxification time.
    Mesh-Begriff(e) Child ; Child, Preschool ; China/epidemiology ; Enterovirus A, Human/pathogenicity ; Feces/virology ; Female ; Hand, Foot and Mouth Disease/epidemiology ; Hand, Foot and Mouth Disease/virology ; Humans ; Infant ; Male ; Polymerase Chain Reaction ; Virus Shedding
    Sprache Englisch
    Erscheinungsdatum 2015-11
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2236681-7
    ISSN 1867-0687 ; 1708-8569
    ISSN (online) 1867-0687
    ISSN 1708-8569
    DOI 10.1007/s12519-015-0045-z
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6309: Hefte anzeigen Standort:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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